Abstract：
:Chylous effusions frequently occur after cardiac surgery due to severe damage to the lymphatic system, thus indicating that the insertion of a chest tube may be necessary. Factor XIII (FXIII) is discussed as being essential for wound healing. The aim of this retrospective study was to evaluate whether the application of a single dose of FXIII results in a reduced amount of pleural effusion, leading to an earlier release of patients from the hospital. The cases of 40 children with severe chylous effusions after open-heart surgery were examined. Twenty patients received FXIII and were compared to 20 age- and weight-matched patients who did not receive FXIII. Major parameters included the amount of effusion before and 1 and 3 days after the application of FXIII; the duration of chest tubes; the total amount of fluid loss via drainage; and the period of hospitalization. FXIII levels in plasma showed an inverse correlation with fluid loss. After application of a single dose of FXIII, a significant reduction of pleural effusion within the first 24 hours was detected. However, no difference was observed between the two groups when comparing the total amount of pleural effusions within the first 72 hours. Finally, the duration of hospitalization did not differ between the FXIII-treated and the control group. A single application of FXIII rapidly reduces the amount of chylous effusions in the early period after open-heart surgery. This effect is detectable only for 24 hours after the treatment and does not alter the further clinical outcome. Prospective clinical trials are warranted to determine if repeated application or a higher dose of FXIII may improve the clinical outcome of chylous leakages in children after open-heart surgery.
journal_name
Pediatr Cardioljournal_title
Pediatric cardiologyauthors
Schroth M,Meißner U,Cesnjevar R,Weyand M,Singer H,Rascher W,Klinge Jdoi
10.1007/s00246-005-0993-5subject
Has Abstractpub_date
2006-01-01 00:00:00pages
56-60issue
1eissn
0172-0643issn
1432-1971pii
10.1007/s00246-005-0993-5journal_volume
27pub_type
杂志文章abstract：:The reported prenatal detection rates (PDRs) for significant congenital heart disease (sCHD) have been suboptimal, even in the current era. Changes in prenatal ultrasound policy and training may lead to improved prenatal detection of sCHD. This study analyzed the results of a policy to assess fetal cardiac outflow tra...
journal_title：Pediatric cardiology
pub_type： 杂志文章
doi：10.1007/s00246-012-0526-y
更新日期：2013-03-01 00:00:00
abstract：:The authors present an unusual complication of the balloon atrial septostomy procedure performed in a neonate with D-transposition of the great arteries. Cardiac tamponade developed shortly after the balloon atrial septostomy procedure and the infant was found to have a tear in the superior aspect of the left atrium, ...
journal_title：Pediatric cardiology
pub_type： 杂志文章
doi：10.1007/BF02076340
更新日期：1983-04-01 00:00:00
abstract：:The purpose of this study was to test the hypothesis that the incidence of crochetage on the R wave in inferior limb leads can be used for the diagnosis of pediatric secundum atrial septal defect (ASD). Two hundred fifty-six children with secundum ASD (case cohort) and 256 age- and gender-matched children without hear...
journal_title：Pediatric cardiology
pub_type： 杂志文章
doi：10.1007/s00246-018-1857-0
更新日期：2018-06-01 00:00:00
abstract：:We analyzed early and late results of surgical treatment of 100 consecutive children with Down's syndrome (DS) and congenital heart defect (CHD) who were operated on between 1990 and 1997. Fifty had common atrioventricular canal (CAVC), 24 ventricular septal defect, 8 the ostium primum atrial septal defect, 8 tetralog...
journal_title：Pediatric cardiology
pub_type： 杂志文章
doi：10.1007/s002469900483
更新日期：1999-09-01 00:00:00
abstract：:Transcatheter pulmonary valve implantation in the setting of right ventricle-to-pulmonary artery conduit dysfunction is a relatively new procedure with encouraging early and midterm results. Malpositioning of the valve during implantation is a potentially serious complication. This report describes a case in which val...
journal_title：Pediatric cardiology
pub_type： 杂志文章
doi：10.1007/s00246-012-0224-9
更新日期：2012-06-01 00:00:00
abstract：:We performed a Waterston's anastomosis on a patient with complicated tricuspid atresia when she was two months of age. At age 14 years she required left pneumonectomy for massive, idiopathic hemoptysis. Four months after the pneumonectomy we substituted a modified Fontan anastomosis for the Waterston anastomosis. Rest...
journal_title：Pediatric cardiology
pub_type： 杂志文章
doi：10.1007/BF02238530
更新日期：1991-07-01 00:00:00
abstract：:With improvements in technology and surgical technique, pediatric cardiologists are challenging surgeons to close symptomatic ventricular septal defects (VSDs) in ever smaller patients. Although delaying surgery may facilitate operative repair, early intervention decreases the period of time these patients require the...
journal_title：Pediatric cardiology
pub_type： 杂志文章
doi：10.1007/s00246-007-9016-z
更新日期：2008-01-01 00:00:00
abstract：:Thrombocytopenia can be a real challenge during cardiac surgery in children with cyanotic congenital heart disease. This report describes a 7-year-old girl with d-transposition of the great arteries, ventricular septal defect, pulmonary hypertension, chronic thrombocytopenia, polycythemia, and chronic renal impairment...
journal_title：Pediatric cardiology
pub_type： 杂志文章
doi：10.1007/s00246-012-0570-7
更新日期：2013-01-01 00:00:00
abstract：:The most common modes of medical education for congenital heart disease (CHD) rely heavily on 2-dimensional imaging. Three-dimensional (3D) printing technology allows for the creation of physical cardiac models that can be used for teaching trainees. 3D printed cardiac models were created for the following lesions: pu...
journal_title：Pediatric cardiology
pub_type： 杂志文章
doi：10.1007/s00246-019-02146-8
更新日期：2019-08-01 00:00:00
abstract：:Branch pulmonary artery stenosis (BPAS) in the setting of systemic-pulmonary artery shunts (SPS) may result in significant sequelae. Limited information exists regarding the safety and efficacy of pulmonary artery balloon angioplasty and stent implantation via SPS in neonates and infants. This study aimed to examine t...
journal_title：Pediatric cardiology
pub_type： 杂志文章
doi：10.1007/s00246-013-0657-9
更新日期：2013-08-01 00:00:00
abstract：:This report describes the case of two pediatric patients who demonstrated echocardiographic evidence of pulmonary hypertension (PH) during the acute phase of Kawasaki disease. The etiology of PH development in this setting is currently unknown, but the authors hypothesize that pulmonary vasculitis may play a significa...
journal_title：Pediatric cardiology
pub_type： 杂志文章,评审
doi：10.1007/s00246-012-0510-6
更新日期：2013-01-01 00:00:00
abstract：:Controversy exists as to whether a hemodynamically significant left-to-right shunt due to a patent ductus arteriosus (PDA) affects ventricular contractility. Load-dependent indices such as ejection fraction and shortening fraction have traditionally been used to assess contractility, but the relationship between the r...
journal_title：Pediatric cardiology
pub_type： 杂志文章
doi：10.1007/s00246-003-0452-0
更新日期：2004-03-01 00:00:00
abstract：:Myocardial blood flow (MBF) was investigated in children (14.2 +/- 5.01 years) with "resolved" coronary involvement after the onset of Kawasaki disease and angiographically normal epicardial coronary arteries. Ten asymptomatic children with a history of Kawasaki disease had electrocardiography, echocardiography, and p...
journal_title：Pediatric cardiology
pub_type： 杂志文章
doi：10.1007/s00246-003-0472-9
更新日期：2004-03-01 00:00:00
abstract：:Dextro-transposition of the great arteries (D-TGA) is one of the most common cyanotic heart lesions. The arterial switch operation (ASO) is the preferred surgical palliation for D-TGA. One of the primary concerns following the ASO is complications arising from the coronary artery transfer. There is a need for myocardi...
journal_title：Pediatric cardiology
pub_type： 杂志文章
doi：10.1007/s00246-018-1890-z
更新日期：2018-08-01 00:00:00
abstract：:A methodology that would allow for comparison of charges across institutions has not been developed for catheterization in congenital heart disease. A single institution catheterization database with prospectively collected case characteristics was linked to hospital charges related and limited to an episode of care i...
journal_title：Pediatric cardiology
pub_type： 杂志文章
doi：10.1007/s00246-014-0994-3
更新日期：2015-02-01 00:00:00
abstract：:Left-ventricular noncompaction (LVNC) is an echocardiographic finding of increasing frequency in pediatrics; however, predictors of outcomes have been difficult to identify. We conducted a retrospective review of pediatric patients at the Morgan Stanley Children's Hospital of New York from January of 1993 to September...
journal_title：Pediatric cardiology
pub_type： 杂志文章
doi：10.1007/s00246-010-9868-5
更新日期：2011-04-01 00:00:00
abstract：:With the advent of cardiac magnetic resonance imaging and high-resolution echocardiography, cardiac catheterization is unnecessary in clinical protocols in the "routine" single ventricle patient. Catheterization adds little to clinical care in these cases, and there are significant risks and costs associated with it. ...
journal_title：Pediatric cardiology
pub_type： 杂志文章,评审
doi：10.1007/s00246-004-0960-6
更新日期：2005-03-01 00:00:00
abstract：:Aortopulmonary window is a relatively uncommon congenital heart defect. We report on a patient with a small aortopulmonary window, who presented with an asymptomatic murmur and in whom catheter closure was successfully performed with an Amplatzer Duct Occluder. ...
journal_title：Pediatric cardiology
pub_type： 杂志文章
doi：10.1007/s00246-002-0307-0
更新日期：2003-05-01 00:00:00
abstract：:Quantification of left ventricular (LV) mass by echocardiography has not been validated against the gold standard of cardiac magnetic resonance imaging (CMR) in the pediatric population. The purpose of this study was to compare LV mass by two-dimensional and conventional M-mode echocardiography versus CMR in children....
journal_title：Pediatric cardiology
pub_type： 杂志文章
doi：10.1007/s00246-018-1991-8
更新日期：2019-02-01 00:00:00
abstract：:The hospitalization of a child for cardiac surgery is known to be a stressful experience for parents. However, little is known about the time course or the relationships between parental stress and the child's actual or perceived recovery. This research aimed to investigate pre- and postoperative parental stress and t...
journal_title：Pediatric cardiology
pub_type： 杂志文章
doi：10.1007/s00246-010-9726-5
更新日期：2010-10-01 00:00:00
abstract：:After surgical repair of an aortic coarctation a term infant presented with severe pulmonary hypertension and cyanosis unresponsive to treatment including extracorporeal membrane oxygenation. The atypical clinical course became apparent once the accompanying diagnosis of congenital alveolar capillary dysplasia with mi...
journal_title：Pediatric cardiology
pub_type： 杂志文章
doi：10.1007/s00246-007-9063-5
更新日期：2008-01-01 00:00:00
abstract：:In this report, we describe a case of coarctation of the aorta, congenital aortic stenosis with bicuspid valve, and supravalvar aortic stenosis with left coronary artery ostial stenosis. The child underwent staged treatment using a hybrid approach employing both surgical and interventional cardiology methods. A single...
journal_title：Pediatric cardiology
pub_type： 杂志文章
doi：10.1007/s002460010164
更新日期：2001-01-01 00:00:00
abstract：:Barth syndrome (BTHS) is an X-linked disorder characterised by cardiomyopathy, neutropenia, skeletal myopathy and growth delay. This study describes the UK national clinical experience and outcome of cardiomyopathy in BTHS. The clinical course and echocardiographic changes of all patients with BTHS in the UK were revi...
journal_title：Pediatric cardiology
pub_type： 杂志文章
doi：10.1007/s00246-015-1260-z
更新日期：2016-01-01 00:00:00
abstract：:We undertook a study to identify the hemodynamic significance of a Doppler-derived gradient across a stenotic pulmonary valve. Furthermore, we attempted to define the optimal plane for velocity data acquisition. A total of 17 children with valvar pulmonary stenosis were evaluated using Doppler echocardiography. Flow-v...
journal_title：Pediatric cardiology
pub_type： 杂志文章
doi：10.1007/BF02081678
更新日期：1989-07-01 00:00:00
abstract：:Ruptured sinus Valsalva aneurysm (SVA) in a patient with tetralogy of Fallot is a very rare cardiac complication. This report describes the case of a 10-year-old Hispanic girl who presented to her cardiologist for a routine transthoracic echocardiography (TTE), which showed a ruptured sinus of Valsalva, with left-to-r...
journal_title：Pediatric cardiology
pub_type： 杂志文章
doi：10.1007/s00246-012-0457-7
更新日期：2013-01-01 00:00:00
abstract：:As our ability to diagnosis cardiomyopathy matures and genetic testing becomes more widespread, there has been an increase in the number of children followed for cardiomyopathy. The purpose of this study was to compare health-related quality of life (HRQoL) between children with cardiomyopathy and healthy controls and...
journal_title：Pediatric cardiology
pub_type： 杂志文章
doi：10.1007/s00246-014-1042-z
更新日期：2015-03-01 00:00:00
abstract：:We present a 2-month-old male infant with thrombosis in the superior vena cava and pericardium due to transient protein C deficiency. Protein C deficiency was related to sepsis and hepatitis-induced liver function impairment. The patient's cardiac anatomy was otherwise normal. The patient was referred to us with signs...
journal_title：Pediatric cardiology
pub_type： 杂志文章
doi：10.1007/s00246-006-1265-8
更新日期：2006-07-01 00:00:00
abstract：:We present a neonatal case with intractable atrial flutter that did not respond to digitalization and electrical cardioversion. Intravenous flecainide administration completely resolved the atrial flutter. Proarrhythmic effects were not induced by flecainide administration. Although the efficacy of flecainide for atri...
journal_title：Pediatric cardiology
pub_type： 杂志文章
doi：10.1007/s00246-003-0226-8
更新日期：2004-03-01 00:00:00
abstract：:We report our findings in the microscopic examination of the conduction system in four infants with glycogen storage disease, one of whom had adequate electrophysiologic studies. The electrophysiologic studies in the latter case showed P-A and A-H intervals at the lower limits of normal, but the H-V interval was just ...
journal_title：Pediatric cardiology
pub_type： 杂志文章
doi：10.1007/BF02265613
更新日期：1982-01-01 00:00:00
abstract：:A two-year-old child who had had palliative surgery as a neonate for an absent right atrioventricular connection and double-inlet ventricle was shown to be developmentally retarded. Trisomy for the short arm of chromosome 8 was demonstrated, resulting from a familial 8:13 translocation, with a high risk of recurrence....
journal_title：Pediatric cardiology
pub_type： 杂志文章
doi：10.1007/BF02306750
更新日期：1984-01-01 00:00:00
