Abstract:
BACKGROUND:The aim of this study was to evaluate the historical cohort of 61 patients with carcinoma of the vulva, treated with radiation therapy from 1986 to 1997. PATIENTS AND METHODS:Twenty-seven patients were submitted to radiation therapy alone and 34 received radiotherapy post limited surgery in early stages and post radical vulvectomy in advanced stages. The dose range varied from 59 to 63 Gy in post-operative patients and 65 Gy to 71 Gy in curative patients. RESULTS:Five-year Overall Survival (OS) and Disease-Free Survival (DFS) for patients treated with irradiation alone and for those treated with post-operative radiotherapy were 50.8% and 69.7%, respectively, without significant statistical difference. For OS multivariate analysis showed statistical difference for stage and age variables, and for stage variable in the case of DFS. CONCLUSION:In early stage vulvar cancer patients OS and DFS are good, with high control rate and low incidence of adverse effect. In loco-regionally-advanced patients, especially in those with stage IV or with > 2 positive lymph nodes, the outcomes are poor.
journal_name
Anticancer Resjournal_title
Anticancer researchauthors
Tombolini V,Raffetto N,Santarelli M,Valeriani M,Necozione S,Masedu F,Enrici RMsubject
Has Abstractpub_date
2005-07-01 00:00:00pages
3089-94issue
4eissn
0250-7005issn
1791-7530journal_volume
25pub_type
杂志文章abstract::The therapeutic results of allogeneic bone marrow transplantation (BMT), following a conditioning regimen of total body irradiation and busulphan and melphalan administration, were evaluated in 20 pediatric patients with high-risk leukemia or lymphoma. Twelve patients received BMT from HLA-matched related (MR) donors ...
journal_title:Anticancer research
pub_type: 杂志文章
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journal_title:Anticancer research
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doi:
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journal_title:Anticancer research
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journal_title:Anticancer research
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journal_title:Anticancer research
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doi:
更新日期:2004-01-01 00:00:00
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journal_title:Anticancer research
pub_type: 杂志文章
doi:
更新日期:2000-03-01 00:00:00
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journal_title:Anticancer research
pub_type: 杂志文章
doi:
更新日期:1998-03-01 00:00:00
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journal_title:Anticancer research
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doi:
更新日期:2004-09-01 00:00:00
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journal_title:Anticancer research
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doi:
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更新日期:2019-07-01 00:00:00
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journal_title:Anticancer research
pub_type: 杂志文章
doi:
更新日期:1992-09-01 00:00:00
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journal_title:Anticancer research
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doi:
更新日期:2000-09-01 00:00:00
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doi:
更新日期:2014-01-01 00:00:00
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journal_title:Anticancer research
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journal_title:Anticancer research
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doi:
更新日期:1999-07-01 00:00:00
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doi:
更新日期:2009-07-01 00:00:00
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pub_type: 杂志文章,评审
doi:
更新日期:2013-07-01 00:00:00
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journal_title:Anticancer research
pub_type: 杂志文章
doi:
更新日期:2006-11-01 00:00:00
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journal_title:Anticancer research
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更新日期:2019-06-01 00:00:00
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journal_title:Anticancer research
pub_type: 杂志文章
doi:
更新日期:2009-07-01 00:00:00
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journal_title:Anticancer research
pub_type: 杂志文章
doi:
更新日期:2005-11-01 00:00:00
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journal_title:Anticancer research
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doi:
更新日期:2009-08-01 00:00:00