当前位置： SCI文献检索 > VACCINE期刊下所有文献 > Pertussis antitoxin decay after vaccination with DTPa. Response to a first booster dose 3 1/2-6 1/2 years after the third vaccine dose.

Pertussis antitoxin decay after vaccination with DTPa. Response to a first booster dose 3 1/2-6 1/2 years after the third vaccine dose.

Abstract：

:Longitudinal serum samples were collected from 542 children that had participated in a Swedish pertussis vaccine trial 1992-1995 [Gustafsson L, Hallander HO, Olin P, Reizenstein E, Storsaeter J. A controlled trial of a two-component acellular, a five-component acellular, and a whole-cell pertussis vaccine. N Engl J Med 1996;334(6):349-355] and who did not contract pertussis. The sera were analyzed for post vaccination antibody decay and for booster response of anti-PT (IgG antibodies against pertussis toxin), as measured by ELISA. Generally, an initial rapid decay of antitoxin antibody concentration was followed by a slower decay; the change occurring when the geometric mean level of antitoxin concentration reached 8-9 ELISA Units/mL (EU/mL). The time needed to reach this level was 8-9 months after the third dose in a 2, 4, and 6 months schedule. A "best-fit" combined regression model was used to predict when 50% of the children have less than the minimum level of detection of anti-PT (1EU/mL). This occurred about 65 months after dose 3 at an age of 6 years. The anti-PT response to a booster dose was evident but the post-booster geometric mean values decreased with number of years after the third dose and the response appeared later. The results indicate that a pre-school booster might be considered at 6 years of age or earlier.

journal_name

Vaccine

journal_title

Vaccine

authors

Hallander HO,Gustafsson L,Ljungman M,Storsaeter J

doi

10.1016/j.vaccine.2005.06.009

subject

Has Abstract

pub_date

2005-11-16 00:00:00

pages

5359-64

issue

46-47

eissn

0264-410X

issn

1873-2518

pii

S0264-410X(05)00602-X

journal_volume

23

pub_type

杂志文章,随机对照试验

相关文献

VACCINE文献大全
  • A novel therapeutic fusion protein vaccine by two different families of heat shock proteins linked with HPV16 E7 generates potent antitumor immunity and antiangiogenesis.

    abstract：:Human papillomaviruses (HPV), particularly HPV16, is considered a necessary cause of cervical and oral cancer. Thus, the development of a therapeutic vaccine against HPV is important for the control of cervical cancer. However, therapeutic vaccination has been limited by inadequate antigen-specific immune responses. H...

    journal_title：Vaccine

    pub_type： 杂志文章

    doi：10.1016/j.vaccine.2007.12.034

    authors： Liu B,Ye D,Song X,Zhao X,Yi L,Song J,Zhang Z,Zhao Q

    更新日期：2008-03-04 00:00:00

  • Prevalence of type-specific human papillomavirus infection among women in France: Implications for screening, vaccination, and a future generation of multivalent HPV vaccines.

    abstract：:To assess human papillomavirus (HPV) prevalence and genotype distribution by age and cervical cytology/histology status among women undergoing routine gynecological examinations, and to discuss the possible impact on preventive strategies. Liquid-based cytology (LBC) samples were tested for HPV DNA, mRNA, and HPV geno...

    journal_title：Vaccine

    pub_type： 杂志文章

    doi：10.1016/j.vaccine.2012.06.013

    authors： Monsonego J,Zerat L,Syrjänen K,Zerat JC,Smith JS,Halfon P

    更新日期：2012-07-27 00:00:00

  • Highly homogenous tri-acylated S-LPS acts as a novel clinically applicable vaccine against Shigella flexneri 2a infection.

    abstract：:Shigellosis, a major cause of diarrhea worldwide, exhibits high morbidity and mortality in children. Specificity of Shigella immunity is determined by the structure of the main protective O-antigen polysaccharide component incorporated into the lipopolysaccharide (LPS) molecule. Endotoxicity, however, precludes LPS cl...

    journal_title：Vaccine

    pub_type： 杂志文章

    doi：10.1016/j.vaccine.2018.12.067

    authors： Ledov VA,Golovina ME,Markina AA,Knirel YA,L'vov VL,Kovalchuk AL,Aparin PG

    更新日期：2019-02-14 00:00:00

  • PED subunit vaccine based on COE domain replacement of flagellin domain D3 improved specific humoral and mucosal immunity in mice.

    abstract：:Porcine epidemic diarrhea (PED) is an important re-emergent infectious disease and inflicts huge economic losses to the swine industry worldwide. To meet the pressing need of developing a safe and cost-efficient PED maternal vaccine, we generated three PED subunit vaccine candidates, using recombined Salmonella flagel...

    journal_title：Vaccine

    pub_type： 杂志文章

    doi：10.1016/j.vaccine.2018.01.086

    authors： Li Q,Peng O,Wu T,Xu Z,Huang L,Zhang Y,Xue C,Wen Z,Zhou Q,Cao Y

    更新日期：2018-03-07 00:00:00

  • Yellow fever vaccine: an updated assessment of advanced age as a risk factor for serious adverse events.

    abstract：:Since 1996, the scientific community has become aware of 14 reports of yellow fever vaccine (YEL)-associated viscerotropic disease (YEL-AVD) cases and four reports of YEL-associated neurotropic disease (YEL-AND) worldwide, changing our understanding of the risks of the vaccine. Based on 722 adverse event reports after...

    journal_title：Vaccine

    pub_type： 杂志文章

    doi：10.1016/j.vaccine.2005.01.089

    authors： Khromava AY,Eidex RB,Weld LH,Kohl KS,Bradshaw RD,Chen RT,Cetron MS,Yellow Fever Vaccine Safety Working Group.

    更新日期：2005-05-09 00:00:00

  • The feasibility of HIV vaccine efficacy trials among Russian injection drug users.

    abstract：:IDU exposure remains a primary driver of the Russian HIV epidemic, and recent incidence data provide little evidence that this epidemic is slowing. While there are multiple important challenges that need to be further explored before starting vaccine trials, most importantly access to evidence-based drug treatment ser...

    journal_title：Vaccine

    pub_type： 杂志文章

    doi：10.1016/j.vaccine.2007.07.028

    authors： Beyrer C,Baral S,Shaboltas A,Dukhovlinova E,Masharsky A,Verevochkin S,Latkin C,Heimer R,Hoffman I,Kozlov A

    更新日期：2007-10-10 00:00:00

  • Decline of varicella vaccination in German surveillance regions after recommendation of separate first-dose vaccination for varicella and measles-mumps-rubella.

    abstract：BACKGROUND:Germany introduced routine varicella (V) vaccination in 2004. Due to a slightly increased risk of febrile convulsions after first-dose application of combined measles-mumps-rubella-varicella (MMRV) vaccine separate first-dose vaccinations with MMR and monovalent V vaccine were recommended in September 2011. ...

    journal_title：Vaccine

    pub_type： 杂志文章

    doi：10.1016/j.vaccine.2013.12.065

    authors： Streng A,Liese JG

    更新日期：2014-02-12 00:00:00

  • The fight against rabies in Africa: From recognition to action.

    abstract：:As a follow-up to the first AfroREB meeting, held in Grand Bassam (Côte d'Ivoire) in March 2008, African rabies experts of the AfroREB network met a second time to complete the evaluation of the rabies situation in Africa and define specific action plans. About 40 French speaking rabies specialists from northern, west...

    journal_title：Vaccine

    pub_type： 杂志文章

    doi：10.1016/j.vaccine.2009.06.030

    authors： Dodet B,Africa Rabies Bureau (AfroREB).

    更新日期：2009-08-13 00:00:00

  • Electroporation improves the efficacy of DNA vaccines in large animals.

    abstract：:It is generally recognized that DNA vaccines are often less effective in large animals than in mice. One possible reason for this reduced effectiveness may be transfection efficiency and the low level of expression elicited by plasmid vectors in large animals. A possible way to improve plasmid gene expression in vivo ...

    journal_title：Vaccine

    pub_type： 杂志文章

    doi：10.1016/s0264-410x(02)00269-4

    authors： Babiuk S,Baca-Estrada ME,Foldvari M,Storms M,Rabussay D,Widera G,Babiuk LA

    更新日期：2002-09-10 00:00:00

  • Comparative analysis of immunization schedules using a novel adenovirus-based immunotherapeutic targeting hepatitis B in naïve and tolerant mouse models.

    abstract：:Development of active targeted immunotherapeutics is a rapid developing field in the arena of chronic infectious diseases. The question of repeated, closely spaced administration of immunotherapeutics to achieve a rapid impact on the replicating agent is an important one. We analyzed here, using a prototype adenovirus...

    journal_title：Vaccine

    pub_type： 杂志文章

    doi：10.1016/j.vaccine.2014.03.089

    authors： Boukhebza H,Dubois C,Koerper V,Evlachev A,Schlesinger Y,Menguy T,Silvestre N,Riedl P,Inchauspé G,Martin P

    更新日期：2014-05-30 00:00:00

  • Immunoresponse to hepatitis B vaccination and adherence campaign among injecting drug users.

    abstract：:Fifty injecting drug users (IDUs) were recruited to evaluate the efficacy of an hepatitis B virus (HBV) vaccination campaign to be carried out in a Public centre for Drug Users (PCDU). The vaccination schedule was successfully performed in most patients, who showed a great interest in this problem. After three doses o...

    journal_title：Vaccine

    pub_type： 杂志文章

    doi：10.1016/s0264-410x(96)00290-3

    authors： Lugoboni F,Migliozzi S,Schiesari F,Pauletto N,Bovo GL,Ciaffoni S,Mezzelani P

    更新日期：1997-06-01 00:00:00

  • Intranasal immunization with SIV virus-like particles (VLPs) elicits systemic and mucosal immunity.

    abstract：:By using a baculovirus expression system, we have successfully produced simian immunodeficiency virus (SIV)-like particles (VLPs) with high levels of biologically active SIV envelope (Env) incorporated on their surfaces. To study whether SIV VLPs represent effective mucosal immunogens, we immunized groups of mice with...

    journal_title：Vaccine

    pub_type： 杂志文章

    doi：10.1016/s0264-410x(02)00160-3

    authors： Yao Q,Vuong V,Li M,Compans RW

    更新日期：2002-06-07 00:00:00

  • Adjuvant activity of immunopotentiating reconstituted influenza virosomes (IRIVs).

    abstract：:Using immunopotentiating, reconstituted influenza virosomes (IRIV) as a delivery vehicle, a number of vaccines have been developed. In humans, IRIV-based vaccines containing hepatitis A and influenza antigens have been found to possess enhanced immunogenicity compared to alum-adsorbed vaccine for hepatitis A or commer...

    journal_title：Vaccine

    pub_type： 杂志文章

    doi：10.1016/s0264-410x(98)00440-x

    authors： Glück R

    更新日期：1999-03-26 00:00:00

  • Passive immunization with llama single-domain antibody fragments reduces foot-and-mouth disease transmission between pigs.

    abstract：:We aim to develop a method that confers rapid protection against foot-and-mouth disease (FMD) by passive immunization with recombinant llama single-domain antibody fragments (VHHs). Previously constructed genetic fusions of two VHHs (VHH2s) that either neutralizes FMDV or binds to porcine immunoglobulin to increase th...

    journal_title：Vaccine

    pub_type： 杂志文章

    doi：10.1016/j.vaccine.2009.01.110

    authors： Harmsen MM,Fijten HP,Engel B,Dekker A,Eblé PL

    更新日期：2009-03-18 00:00:00

  • Bluetongue virus serotype 8 virus-like particles protect sheep against virulent virus infection as a single or multi-serotype cocktail immunogen.

    abstract：:Since 1998, there have been multiple separate outbreaks of Bluetongue disease (BT) in Europe with the largest outbreak ever recorded in Northern Europe caused by Bluetongue virus serotype 8 (BTV-8). Coinciding with the BTV-8 outbreak, a virulent strain of BTV-1 emerged and co-infections of these two serotypes were rep...

    journal_title：Vaccine

    pub_type： 杂志文章

    doi：10.1016/j.vaccine.2012.11.016

    authors： Stewart M,Dubois E,Sailleau C,Bréard E,Viarouge C,Desprat A,Thiéry R,Zientara S,Roy P

    更新日期：2013-01-07 00:00:00

  • Immunogenicity of multivalent Shigella-ETEC candidate vaccine strains in a guinea pig model.

    abstract：:Shigella and enterotoxigenic Escherichia coli continue to be significant causes of diarrheal disease in infants and young children in developing countries as well as prevalent agents of traveler's diarrhea. A vaccine which provides protection against disease caused by both pathogens would serve common at-risk populati...

    journal_title：Vaccine

    pub_type： 杂志文章

    doi：10.1016/j.vaccine.2005.07.013

    authors： Barry EM,Wang J,Wu T,Davis T,Levine MM

    更新日期：2006-05-01 00:00:00

  • An IL-15 adjuvant enhances the efficacy of a combined DNA vaccine against Brucella by increasing the CD8+ cytotoxic T cell response.

    abstract：:We investigated whether a combined DNA vaccine delivered together with the IL-15 gene (DNA-IL-15(+)) enhanced the immune response against Brucella abortus in mice. Mice vaccinated with DNA-IL-15(+) developed a robust humoral response; Brucella-specific antibodies exhibited a dominance of immunoglobulin G2a (IgG2a) ove...

    journal_title：Vaccine

    pub_type： 杂志文章

    doi：10.1016/j.vaccine.2009.12.076

    authors： Hu XD,Chen ST,Li JY,Yu DH,Yi-Zhang,Cai H

    更新日期：2010-03-11 00:00:00

  • Status of natural infection with Japanese encephalitis virus in Japan: prevalence of antibodies to the nonstructural 1 protein among humans and horses.

    abstract：:The literature on natural infections with Japanese encephalitis virus in Japan and subclinical:clinical infection rates was summarized. To detect natural infections, conventional serologic methods were used in the past, while nonstructural 1 protein-based methods have been used recently. Annual infection rates in huma...

    journal_title：Vaccine

    pub_type： 杂志文章

    doi：10.1016/j.vaccine.2009.09.052

    authors： Konishi E

    更新日期：2009-11-23 00:00:00

  • No major outbreaks of pseudorabies virus in well-immunized sow herds.

    abstract：:In this study we quantified the transmission of pseudorabies virus (PRV) in well-immunized sow herds in The Netherlands. In three herds, sows were tested for antibodies to gE of PRV every time after they had been transported to another barn (survey A). In 99 other herds, sows were tested simultaneously once or twice y...

    journal_title：Vaccine

    pub_type： 杂志文章

    doi：10.1016/0264-410x(96)00022-9

    authors： Van Nes A,Stegeman JA,De Jong MC,Loeffen WL,Kimman TG,Verheijden JH

    更新日期：1996-08-01 00:00:00

  • The effect of routine vaccination on invasive pneumococcal infections in Canadian children, Immunization Monitoring Program, Active 2000-2007.

    abstract：:Active surveillance was conducted by the 12 centers of the Canadian Immunization Monitoring Program, Active from 2000-2007 in children 16 years of age and younger to determine the influence of 7-valent pneumococcal conjugate immunization programs on the prevalence, serotype and antibiotic resistance patterns of invasi...

    journal_title：Vaccine

    pub_type： 杂志文章,多中心研究

    doi：10.1016/j.vaccine.2009.12.026

    authors： Bettinger JA,Scheifele DW,Kellner JD,Halperin SA,Vaudry W,Law B,Tyrrell G,Canadian Immunization Monitoring Program, Active (IMPACT).

    更新日期：2010-02-25 00:00:00

  • Influenza antigen-sparing by immune stimulation with Gram-positive enhancer matrix (GEM) particles.

    abstract：:Gram-positive enhancer matrix (GEM) particles, produced from non-genetically modified Lactococcus lactis bacteria have an inherent immunostimulatory activity. It was investigated whether co-administration of GEM particles can reduce the amount of influenza subunit vaccine (HA) necessary to protect mice from viral infe...

    journal_title：Vaccine

    pub_type： 杂志文章

    doi：10.1016/j.vaccine.2010.09.066

    authors： Saluja V,Visser MR,Ter Veer W,van Roosmalen ML,Leenhouts K,Hinrichs WL,Huckriede A,Frijlink HW

    更新日期：2010-11-23 00:00:00

  • Altered pathogenicity, immunogenicity, tissue tropism and 3'-7kb region sequence of an avian infectious bronchitis coronavirus strain after serial passage in embryos.

    abstract：:In this study, we attenuated a Chinese LX4-type nephropathogenic infectious bronchitis virus (IBV) strain, CK/CH/LHLJ/04V, by serial passage in embryonated chicken eggs. Based on sequence analysis of the 3'-7kb region, the CK/CH/LHLJ/04V virus population contained subpopulations with a mixture of genetic mutants. The ...

    journal_title：Vaccine

    pub_type： 杂志文章

    doi：10.1016/j.vaccine.2009.05.072

    authors： Liu S,Zhang X,Gong L,Yan B,Li C,Han Z,Shao Y,Li H,Kong X

    更新日期：2009-07-23 00:00:00

  • Immune responses and protective efficacy of a recombinant swinepox virus expressing HA1 against swine H1N1 influenza virus in mice and pigs.

    abstract：:Swine influenza virus (SIV) is not only an important respiratory pathogen in pigs but also a potent threat to human health. Although immunization with recombinant poxviruses expressing protective antigens as vaccines has been widely used for against many infectious diseases, development of recombinant swinepox virus (...

    journal_title：Vaccine

    pub_type： 杂志文章

    doi：10.1016/j.vaccine.2012.02.028

    authors： Xu J,Huang D,Liu S,Lin H,Zhu H,Liu B,Lu C

    更新日期：2012-04-26 00:00:00

  • Analogues of muramyl dipeptide (MDP) and tuftsin limit infection and inflammation in murine model of sepsis.

    abstract：:Pharmacological manipulation of the balance between pro- and anti-inflammatory mediators emerges as a key aspect of a successful treatment of sepsis. A murine model of septic shock was developed and chosen conjugates (1a, 1b, 8a, 8c) and analogs (T2) of muramyl dipeptide and tuftsin were tested in this model as prospe...

    journal_title：Vaccine

    pub_type： 杂志文章

    doi：10.1016/j.vaccine.2008.11.017

    authors： Wardowska A,Dzierzbicka K,Szaryńska M,Dabrowska-Szponar M,Wiśniewska K,Myśliwski A,Trzonkowski P

    更新日期：2009-01-14 00:00:00

  • Role of lipid structure in the humoral immune response in mice to covalent lipid-peptides from the membrane proximal region of HIV-1 gp41.

    abstract：:The membrane proximal region (MPR) of HIV-1 gp41 is a desirable target for development of a vaccine that elicits neutralizing antibodies since the patient-derived monoclonal antibodies, 2F5 and 4E10, bind to the MPR and neutralize primary HIV isolates. The 2F5 and 4E10 antibodies cross-react with lipids and structural...

    journal_title：Vaccine

    pub_type： 杂志文章

    doi：10.1016/j.vaccine.2009.05.059

    authors： Watson DS,Szoka FC Jr

    更新日期：2009-07-23 00:00:00

  • A SARS DNA vaccine induces neutralizing antibody and cellular immune responses in healthy adults in a Phase I clinical trial.

    abstract：BACKGROUND:The severe acute respiratory syndrome (SARS) virus is a member of the Coronaviridae (CoV) family that first appeared in the Guangdong Province of China in 2002 and was recognized as an emerging infectious disease in March 2003. Over 8000 cases and 900 deaths occurred during the epidemic. We report the safety...

    journal_title：Vaccine

    pub_type： 杂志文章

    doi：10.1016/j.vaccine.2008.09.026

    authors： Martin JE,Louder MK,Holman LA,Gordon IJ,Enama ME,Larkin BD,Andrews CA,Vogel L,Koup RA,Roederer M,Bailer RT,Gomez PL,Nason M,Mascola JR,Nabel GJ,Graham BS,VRC 301 Study Team.

    更新日期：2008-11-25 00:00:00

  • The expanded programme on immunization: a lasting legacy of smallpox eradication.

    abstract：:Since the mid-1970s, the widespread establishment and implementation of the Expanded Programme on Immunization (EPI) has led to remarkable achievements in controlling vaccine preventable diseases worldwide. Today, more children than ever are being reached with immunization; interruption of poliomyelitis transmission h...

    journal_title：Vaccine

    pub_type： 杂志文章,评审

    doi：10.1016/j.vaccine.2012.01.080

    authors： Okwo-Bele JM,Cherian T

    更新日期：2011-12-30 00:00:00

  • A response to Fu et al.'s "Educational interventions to increase HPV vaccination acceptance".

    abstract：:This commentary is a response to a systematic review, recently published in Vaccine, which investigates the effectiveness of educational interventions in increasing uptake of the human papillomavirus vaccine. The systematic review by Fu et al. (2014) enhances the field's understanding of human papillomavirus vaccine i...

    journal_title：Vaccine

    pub_type： 评论,杂志文章

    doi：10.1016/j.vaccine.2014.09.045

    authors： Shapiro GK,Joyal-Desmarais K,Perez S,Rosberger Z

    更新日期：2014-11-12 00:00:00

  • New avian suspension cell lines provide production of influenza virus and MVA in serum-free media: studies on growth, metabolism and virus propagation.

    abstract：:Few suspension cells can be used for vaccine manufacturing today as they either do not meet requirements from health regulatory authorities or do not produce high virus titres. Two new avian designer cell lines (AGE1.CR and AGE1.CR.pIX) that have been adapted to grow in suspension in serum-free medium were evaluated f...

    journal_title：Vaccine

    pub_type： 杂志文章

    doi：10.1016/j.vaccine.2009.05.083

    authors： Lohr V,Rath A,Genzel Y,Jordan I,Sandig V,Reichl U

    更新日期：2009-08-06 00:00:00

  • Targeting of envelope domain III protein of DENV type 2 to DEC-205 receptor elicits neutralizing antibodies in mice.

    abstract：:Dengue virus (DENV) is the causal agent of severe disease and, in some cases, mortality in humans, but no licensed vaccines against dengue are available. An effective vaccine against dengue requires long-term humoral and cellular immune responses. Several viral proteins have been the subjects of intense research, espe...

    journal_title：Vaccine

    pub_type： 杂志文章

    doi：10.1016/j.vaccine.2013.03.009

    authors： Coconi-Linares N,Ortega-Dávila E,López-González M,García-Machorro J,García-Cordero J,Steinman RM,Cedillo-Barrón L,Gómez-Lim MA

    更新日期：2013-05-01 00:00:00