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Early atherosclerosis in childhood: diagnostic approaches and therapeutic strategies.

Abstract：

:The long preclinical phase of atherosclerosis involves the interaction of genetic and environmental factors that modulate the progression of disease from early life. Injury to the endothelium is a critical step in atherosclerotic process. Conventional and novel risk factors for coronary artery disease operate from early in life. Noninvasive methods, using mostly ultrasound techniques, have enabled the assessment of early functional and structural arterial disease progression even from the first decade of life. These measures have been shown to be good surrogate markers for atherosclerotic disease progression and future clinical cardiovascular events. Lifestyle and dietary modifications as well as pharmacological interventions have beneficial effects in prevention and restoration of the early arterial changes.

journal_name

Int J Cardiol

journal_title

International journal of cardiology

authors

Charakida M,Tousoulis D,Stefanadis C

doi

10.1016/j.ijcard.2005.06.010

subject

Has Abstract

pub_date

2006-05-10 00:00:00

pages

152-9

issue

2

eissn

0167-5273

issn

1874-1754

pii

S0167-5273(05)00834-X

journal_volume

109

pub_type

杂志文章,评审

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