Abstract:
:Based on an adaptive genetic fuzzy clustering algorithm, a derived fuzzy knowledge model is proposed for quantitatively estimating the systolic arterial pressure (SAP), heart rate (HR), and bispectral index (BIS) using 12 patients and it validates them according to pharmacological reasoning. Also, a genetic proportional integral derivative controller (GPIDC) to adaptive three controller parameters and a genetic fuzzy logic controller (GFLC) to adaptive controller rules using genetic algorithms (GAs) were simulated and compared each other in a patient model using the BIS value as a controlled variable. Each controller was tested using a set of 12 virtual patients undergoing a Gaussian random surgical disturbance repeated with BIS targets set at 40, 50, and 60. Controller performance was assessed using mean absolute error (MAE) of the BIS target, the percentage of time with acceptable BIS control (PTABC), and drug consumption (DC). It was found that the MAE value of the BIS target was significantly lower (P < 0.05) and the values of PTABC and DC of BIS target were significantly higher (P < 0.05) in BIS targets set at 40 than at 50 or 60 in both GPIDC and GFLC. However, when compared with two controllers in terms of the values of MAE, PTABC, and DC each other in BIS targets set at 40, 50, and 60, there were no significant differences (P > 0.05). Furthermore, when the simulation results in these two controllers were compared with routine standard practice of 12 clinical trials (i.e., manual control) in BIS target set at 50, the values of PTABC in both GPIDC and GFLC groups were significantly higher (P < 0.05) than in the manual control group. In contrast, there were no significant differences (P > 0.05) for these three groups in terms of drug consumption. This indicates that either GPIDC or GFLC can control the BIS target set at 50 better than manual control, although the similar drug consumption is used.
journal_name
Med Eng Physjournal_title
Medical engineering & physicsauthors
Shieh JS,Kao MH,Liu CCdoi
10.1016/j.medengphy.2005.04.023subject
Has Abstractpub_date
2006-03-01 00:00:00pages
134-48issue
2eissn
1350-4533issn
1873-4030pii
S1350-4533(05)00098-6journal_volume
28pub_type
杂志文章,随机对照试验abstract::There is an increasing awareness among the populace of the need for regular health check-up to detect diseases in their early stages and thereby administer treatments in a timely fashion. However, commercially available physiological signal monitoring devices, which may offer clues on the onset of diseases, are time-c...
journal_title:Medical engineering & physics
pub_type: 杂志文章
doi:10.1016/j.medengphy.2011.04.011
更新日期:2013-02-01 00:00:00
abstract::Some pulmonary diseases and injuries are believed to correlate with lung viscoelasticity changes. Hence, a better understanding of lung viscoelastic models could provide new perspectives on the progression of lung pathology and trauma. In the presented study, stress relaxation measurements were performed to quantify r...
journal_title:Medical engineering & physics
pub_type: 杂志文章
doi:10.1016/j.medengphy.2015.05.003
更新日期:2015-08-01 00:00:00
abstract::In this paper, we derive a comprehensive computational model to estimate the arterial pressure and the cardiac output of humans, by refining and adapting the well-established equations of the Windkessel theory. The model inputs are based on patient specific factors such as age, sex, smoking and fitness habits as well ...
journal_title:Medical engineering & physics
pub_type: 杂志文章
doi:10.1016/j.medengphy.2008.11.010
更新日期:2009-06-01 00:00:00
abstract::The impeller blood pump with its simplicity has many advantages compared with the diaphragm pump, but the nonpulsatile property has limited its applications. To make the impeller pump pulsatile, many investigations have been made in vain because of resulting haemolysis. The author has succeeded in producing a pulsatil...
journal_title:Medical engineering & physics
pub_type: 杂志文章
doi:10.1016/1350-4533(95)00010-0
更新日期:1996-01-01 00:00:00
abstract::Numerical simulations of eye globes often rely on topographies that have been measured in vivo using devices such as the Pentacam or OCT. The topographies, which represent the form of the already stressed eye under the existing intraocular pressure, introduce approximations in the analysis. The accuracy of the simulat...
journal_title:Medical engineering & physics
pub_type: 杂志文章
doi:10.1016/j.medengphy.2012.09.006
更新日期:2013-02-01 00:00:00
abstract::This study presents a theoretical model of the general stress state found in helical implantable leads in bending. The model accurately predicts stress in large filarity coils made from clad wire. The stress is predicted using flexural rigidity of the coil and is developed to include the effects of coil pitch and the ...
journal_title:Medical engineering & physics
pub_type: 杂志文章
doi:10.1016/s1350-4533(96)00022-7
更新日期:1997-10-01 00:00:00
abstract::Quantification in clinical, diagnostic electromyography (EMG) currently includes motor unit action potential (MUAP) analysis and interference pattern analysis. Early efforts to examine the frequency/power spectra of the interference pattern showed modest value but the technique was not developed further. This paper re...
journal_title:Medical engineering & physics
pub_type: 杂志文章
doi:10.1016/j.medengphy.2011.07.017
更新日期:2012-03-01 00:00:00
abstract::Hepatic venous pressure gradient (HVPG) is a hemodynamic index widely used for evaluating the severity of portal hypertension. Theoretically, HVPG can be measured in any of the three major (i.e., right, middle and left) hepatic veins (HVs); however, it remains unclear whether HVPGs measured in different HVs are exchan...
journal_title:Medical engineering & physics
pub_type: 杂志文章
doi:10.1016/j.medengphy.2020.07.022
更新日期:2020-10-01 00:00:00
abstract::Spinal pedicle screw fixations have been used extensively to treat fracture, tumor, infection, or degeneration of the spine. Cannulated spinal pedicle screws with bone cement augmentation might be a useful method to ameliorate screw loosening. However, cannulated spinal pedicle screws might also increase the risk of s...
journal_title:Medical engineering & physics
pub_type: 杂志文章
doi:10.1016/j.medengphy.2015.06.008
更新日期:2015-09-01 00:00:00
abstract::Post-myocardial infarction remodeling process is known to alter the mechanical properties of the heart. Biomechanical parameters, such as tissue stiffness and contractility, would be useful for clinicians to better assess the severity of the diseased heart. However, these parameters are difficult to obtain in the curr...
journal_title:Medical engineering & physics
pub_type: 杂志文章
doi:10.1016/j.medengphy.2020.09.003
更新日期:2020-11-01 00:00:00
abstract::Scoliosis is a 3D deformity of the spine and rib cage. Extensive validation of 3D reconstruction methods of the spine from biplanar radiography has already been published. In this article, we propose a novel method to reconstruct the rib cage, using the same biplanar views as for the 3D reconstruction of the spine, to...
journal_title:Medical engineering & physics
pub_type: 杂志文章
doi:10.1016/j.medengphy.2013.06.002
更新日期:2013-11-01 00:00:00
abstract::Precise evaluation of graft reperfusion is difficult in clinical liver transplantation. The oxygen electrode (OE) is a novel technique to detect blood flow indirectly by measuring the quantity of oxygen which can diffuse from the hepatic tissue to the surface electrode. Application of the surface OE does not influence...
journal_title:Medical engineering & physics
pub_type: 杂志文章
doi:10.1016/s1350-4533(00)00060-6
更新日期:2000-06-01 00:00:00
abstract::The Fit4Purpose project aims to develop upper limb prosthetic devices which are suitable for deployment in lower- and middle-income countries (LMIC's). Open-frame trans-radial socket designs are being considered, formed of several, linked components, including pads which interface directly with the skin surface. A mec...
journal_title:Medical engineering & physics
pub_type: 杂志文章
doi:10.1016/j.medengphy.2020.08.003
更新日期:2020-10-01 00:00:00
abstract::Lung cancer is the most common cause of cancer-related death, and early detection can reduce the mortality rate. Patients with lung nodules greater than 10 mm usually undergo a computed tomography (CT)-guided biopsy. However, aligning the needle with the target is difficult and the needle tends to deflect from a strai...
journal_title:Medical engineering & physics
pub_type: 杂志文章
doi:10.1016/j.medengphy.2017.04.009
更新日期:2017-07-01 00:00:00
abstract::We investigated whether automatic control of a hand grasp neuroprosthesis by means of signals from natural sensors in the skin of the index finger can mimic the natural control of grasp force in an important task of daily living, namely eating. We designed a simulated eating task with the same ratio of rest and activi...
journal_title:Medical engineering & physics
pub_type: 临床试验,杂志文章
doi:10.1016/j.medengphy.2004.03.002
更新日期:2004-07-01 00:00:00
abstract::Biomagnetic investigations in basic physiological research using animals require measurement devices different from commercial biomagnetometers used in human investigations. Two major problems have to be tackled in the design of such biomagnetometers. First, the spatial sampling needs to be much higher. Second, the di...
journal_title:Medical engineering & physics
pub_type: 杂志文章
doi:10.1016/s1350-4533(99)00088-0
更新日期:1999-10-01 00:00:00
abstract::Beat detection is a basic and fundamental step in electrocardiogram (ECG) processing. In many ECG applications strong artifacts from biological or technical sources could appear and cause distortion of ECG signals. Beat detection algorithm desired property is to avoid these distortions and detect beats in any situatio...
journal_title:Medical engineering & physics
pub_type: 杂志文章
doi:10.1016/j.medengphy.2012.07.017
更新日期:2013-06-01 00:00:00
abstract::Using an anaesthetized cat's central footpad pressed against an object as the model of a paralyzed human hand, a nerve signal recording system was developed to measure the effect of a group of consecutive slips between the footpad and the object. Electroneurographic (ENG) activity was recorded using a cuff electrode i...
journal_title:Medical engineering & physics
pub_type: 杂志文章
doi:10.1016/j.medengphy.2007.05.007
更新日期:2008-05-01 00:00:00
abstract::Metal plates are commonly used in the operative treatment of bone fractures. Rigid metal plates stabilize the fracture site, maintain good contact between bone fragments and allow early weight bearing and patient mobility. However, treatment with rigid metal plates can cause localized bone atrophy due to stress-shield...
journal_title:Medical engineering & physics
pub_type: 杂志文章
doi:10.1016/1350-4533(95)00041-0
更新日期:1996-04-01 00:00:00
abstract:BACKGROUND AND AIMS OF THE STUDY:Mechanical heart valves (MHV) are widely used to replace dysfunctional and failed heart valves. The bileaflet MHV design is very popular due to its superior hemodynamics. Since their introduction in 1977, the hemodynamics of bileaflet prostheses has been extensively studied. In this stu...
journal_title:Medical engineering & physics
pub_type: 杂志文章
doi:10.1016/j.medengphy.2005.03.013
更新日期:2006-03-01 00:00:00
abstract::Balance impairment is critical for many patient groups such as those with neural and musculoskeletal disorders and also the elderly. Accurate and objective assessment of balance performance has led to the development of several indices based on the measurement of the center of pressure. In this study, a robotic device...
journal_title:Medical engineering & physics
pub_type: 杂志文章
doi:10.1016/j.medengphy.2020.07.006
更新日期:2020-09-01 00:00:00
abstract::The investigation of patellar tendon reflex involves development of a reflex hammer holder, kinematic data collection and analysis of patellar reflex responses using motion analysis techniques. The main aim of this research is to explore alternative means of assessing reflexes as a part of routine clinical diagnosis. ...
journal_title:Medical engineering & physics
pub_type: 临床试验,杂志文章
doi:10.1016/j.medengphy.2010.11.002
更新日期:2011-05-01 00:00:00
abstract::The spectral local F-test has been applied for detecting evoked responses to rhythmic stimulation that are embedded in the ongoing electroencephalogram (EEG). Based on the sampling distribution of a flat spectrum at the neighbourhood of the stimulation frequency, spectral peaks in an EEG signal that are due to the sti...
journal_title:Medical engineering & physics
pub_type: 杂志文章
doi:10.1016/j.medengphy.2017.06.032
更新日期:2017-10-01 00:00:00
abstract::This investigation explored pattern recognition of EMG signals produced by shoulder area muscles to identify the performance of a select number of lower arm motions. The signals were modelled as fourth-order autoregressive processes with the parameters of the models used to classify the different motions. The recorded...
journal_title:Medical engineering & physics
pub_type: 杂志文章
doi:10.1016/1350-4533(94)90024-8
更新日期:1994-03-01 00:00:00
abstract::Core decompression is the most common procedure for treatment of the early stages of osteonecrosis of the femoral head. The purpose of this study was to compare the biomechanical performance of four different bone graft substitutes combined with core decompression. Subject-specific finite element models generated from...
journal_title:Medical engineering & physics
pub_type: 杂志文章
doi:10.1016/j.medengphy.2016.05.008
更新日期:2016-09-01 00:00:00
abstract::A DNA electrochemical biosensor is an integrated receptor-transducer device. The most important step in the development and manufacture of a sensitive DNA-biosensor for the detection of DNA-drug interactions is the immobilization procedure of the nucleic acid probe on the transducer surface. Magnetic A/C Mode atomic f...
journal_title:Medical engineering & physics
pub_type: 杂志文章
doi:10.1016/j.medengphy.2006.05.009
更新日期:2006-12-01 00:00:00
abstract::It is important to be able to quantify changes in gait pattern accurately in order to understand the clinical implications of surgery or rehabilitation. Although supervised feed-forward backpropagation neural networks are very efficient in many pattern-recognition tasks, the genetic algorithm neural network (GANN), wh...
journal_title:Medical engineering & physics
pub_type: 杂志文章
doi:10.1016/s1350-4533(00)00011-4
更新日期:2000-01-01 00:00:00
abstract::The standard camera- and force plate-based set-up for motion analysis suffers from the disadvantage of being limited to laboratory settings. Since adaptive algorithms are able to learn the connection between known inputs and outputs and generalise this knowledge to unknown data, these algorithms can be used to leverag...
journal_title:Medical engineering & physics
pub_type: 杂志文章
doi:10.1016/j.medengphy.2020.10.001
更新日期:2020-12-01 00:00:00
abstract:OBJECTIVE:Mathematical modeling of cerebral hemodynamics by descriptive equations can estimate the underlying pulsatile component of cerebral arterial blood volume (CaBV). This way, clinical monitoring of changes in cerebral compartmental compliances becomes possible. Our aim is to validate the most adequate method of ...
journal_title:Medical engineering & physics
pub_type: 杂志文章
doi:10.1016/j.medengphy.2019.07.019
更新日期:2019-12-01 00:00:00
abstract::The reliability of internal joint moment calculation in gait analysis during daily living activities is fundamental for clinical decisions based on joint function. This calculation, obtained by means of the inverse dynamics, depends on several modelling factors, such as assumptions on the segments and on the relevant ...
journal_title:Medical engineering & physics
pub_type: 临床试验,杂志文章
doi:10.1016/j.medengphy.2004.12.002
更新日期:2005-07-01 00:00:00