Sorting of proteins to storage vacuoles: how many mechanisms?

Abstract:

:Vacuoles receive their proteins through the secretory pathway, this requires protein sorting signals and molecular machineries that, until recently, have been believed to be markedly distinct for lytic and storage vacuoles. However, new biochemical, morphological and genetic data indicate that the only known class of vacuolar sorting receptors, believed to be specific for lytic vacuoles, might also be involved in the sorting of certain storage proteins. Furthermore, storage vacuoles can have a complex multimembrane structure that is difficult to explain based on a single trafficking mechanism. A new array of possible molecular interactions is thus emerging that no longer supports a clear-cut distinction between the two types of vacuoles based on sorting signals and putative receptors.

journal_name

Trends Plant Sci

journal_title

Trends in plant science

authors

Vitale A,Hinz G

doi

10.1016/j.tplants.2005.05.001

subject

Has Abstract

pub_date

2005-07-01 00:00:00

pages

316-23

issue

7

eissn

1360-1385

issn

1878-4372

pii

S1360-1385(05)00119-6

journal_volume

10

pub_type

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