Lipid profile and anticardiolipin antibodies in Behcet's disease.

Abstract:

BACKGROUND:Behcet's disease (BD) is a multisystem disorder characterized by a relapsing inflammatory process of unknown etiology. It is well known that atherothrombosis in systemic inflammatory disorders is closely related to coagulation and lipid metabolism abnormalities. The purpose of this study was to investigate some parameters of lipid metabolism, lipoprotein (a) [Lp(a)] and anticardiolipin antibody (ACA) levels and the relationship of these parameters with the clinical activity of BD. METHODS:Thirty three patients with BD (15 active, 18 inactive cases) and 20 healthy controls participated in the study. After performing a detailed physical exam, erythrocyte sedimentation rate (ESR), C-reactive protein (CRP), total cholesterol (TC), triglycerides (TG), high-density lipoprotein cholesterol (HDL-C), low-density lipoprotein cholesterol (LDL-C), very-low-density lipoprotein cholesterol (VLDL-C), apoprotein A and B (apo-A, apo-B), Lp(a), and ACA levels (ACA-IgG and IgM) were measured in all participants. RESULTS:Patients with active BD had higher ESR, CRP and Lp(a) levels, and lower apo-A and HDL-C levels compared with the patients with inactive BD and healthy controls. ACA-IgG and IgM levels were higher in patients with active BD than healthy controls but not higher than patients with inactive BD. On the other hand, ACA-IgG level was higher in active and inactive cases with vascular involvement than in those of active and inactive cases without vascular involvement. In the analyses of correlation, in active BD patients we found a positive correlation between CRP and Lp(a) levels. CONCLUSIONS:Our findings suggest that Lp(a) behaves as an acute phase reactant and ACA levels are increased in patients with active BD. Data from patients with active BD may be compatible with the serum profile, which is accepted as a risk for the development of atherothrombosis.

journal_name

Arch Med Res

authors

Musabak U,Baylan O,Cetin T,Yesilova Z,Sengul A,Saglam K,Inal A,Kocar IH

doi

10.1016/j.arcmed.2005.03.019

subject

Has Abstract

pub_date

2005-07-01 00:00:00

pages

387-92

issue

4

eissn

0188-4409

issn

1873-5487

pii

S0188-4409(05)00092-5

journal_volume

36

pub_type

杂志文章
  • Influence of 1800 MHz GSM-like electromagnetic radiation exposure on fracture healing.

    abstract:BACKGROUND AND AIMS:In this study, we aimed to investigate whether 1800 MHz frequency electromagnetic radiation (EMR) has an effect on bone healing. METHODS:A total of 30 Wistar albino rats were divided into two equal groups. Fractures were created in the right tibias of all rats; next, intramedullary fixations with K...

    journal_title:Archives of medical research

    pub_type: 杂志文章

    doi:10.1016/j.arcmed.2014.01.006

    authors: Aslan A,Kırdemır V,Kocak A,Atay T,Baydar ML,Özerdemoglu RA,Aydogan NH

    更新日期:2014-02-01 00:00:00

  • Association of serum lipid/lipoprotein with Pro12Ala polymorphism in PPAR-γ2 among Chinese nonagenarians/centenarians.

    abstract:BACKGROUND AND AIMS:In previous studies, the Pro12Ala polymorphism in the peroxisome proliferator-activated receptor gamma 2 (PPAR-γ2) was shown to be associated with both lipid metabolism and longevity. We examined whether the polymorphism continued to be associated with abnormal levels of serum lipid/lipoprotein amon...

    journal_title:Archives of medical research

    pub_type: 杂志文章

    doi:10.1016/j.arcmed.2011.09.010

    authors: Chang-Quan H,Hui W,Qing-Xiu L,Gang C

    更新日期:2011-10-01 00:00:00

  • Expression of Jagged1/Notch3 Signaling Pathway and their Relationship with the Tumor Angiogenesis in TNBC.

    abstract:BACKGROUND AND AIMS:Jagged1/Notch3 signaling pathway plays a key role in angiogenesis of breast cancer, but little is known in TNBC. This study was designed to investigate the expression of Jagged1/Notch3 mRNA and protein in TNBC, analyze their correlations with clinicopathological characteristics and prognosis. Moreov...

    journal_title:Archives of medical research

    pub_type: 杂志文章

    doi:10.1016/j.arcmed.2017.03.014

    authors: Xue S,He L,Zhang X,Zhou J,Li F,Wang X

    更新日期:2017-02-01 00:00:00

  • Metabolic acidosis in AIDS patients.

    abstract:BACKGROUND AND AIMS:Metabolic acidosis (MA) is a frequent and serious complication in HIV-infected patients. The aim of the study is to compare patients with and without MA associated with HIV. METHODS:Patients were retrospectively studied involving all HIV-infected patients with blood gas analysis performed during ho...

    journal_title:Archives of medical research

    pub_type: 杂志文章

    doi:10.1016/j.arcmed.2008.12.004

    authors: Daher EF,Cezar LC,Silva GB Jr,Lima RS,Damasceno LS,Lopes EB,Nunes FR,Mota RS,Libório AB

    更新日期:2009-02-01 00:00:00

  • Adherence to treatment: the key for avoiding long-term complications of diabetes.

    abstract::Behavioral changes and adherence to pharmacological treatment are essential for improving the prognosis in chronic illness. Lack of adherence to treatment is a common problem in every practice and many patients drop out of care prematurely. The present article is a review of our knowledge regarding adherence to treatm...

    journal_title:Archives of medical research

    pub_type: 杂志文章,评审

    doi:10.1016/j.arcmed.2004.12.001

    authors: Lerman I

    更新日期:2005-05-01 00:00:00

  • Human acute myeloid leukemia stem cells.

    abstract::Acute myeloid leukemia (AML) is a clonal disorder defined by the accumulation of abnormally differentiated myeloid cells that are not mature; any myeloid lineage can be affected and the extent of maturation of the leukemia blasts can also vary. Because mature blast cells of AML have very limited proliferative capacity...

    journal_title:Archives of medical research

    pub_type: 杂志文章,评审

    doi:10.1016/j.arcmed.2003.08.007

    authors: Hope KJ,Jin L,Dick JE

    更新日期:2003-11-01 00:00:00

  • A 63 kDa VSP9B10A-like protein expressed in a C-8 Giardia duodenalis Mexican clone.

    abstract:BACKGROUND:It is well documented that Giardia duodenalis undergoes surface antigenic variation both in vivo and in vitro. Proteins involved have been characterized and referred to as VSP (variable surface protein). METHODS:Two cloned cDNA inserts of 0.45 and 1.95 kb were obtained from G. duodenalis expression library ...

    journal_title:Archives of medical research

    pub_type: 杂志文章

    doi:10.1016/j.arcmed.2003.12.005

    authors: Bermúdez-Cruz RM,Ortega-Pierres G,Ceja V,Coral-Vázquez R,Fonseca R,Cervantes L,Sánchez A,Depardón F,Newport G,Montañéz C

    更新日期:2004-05-01 00:00:00

  • Neuropsychology of Alzheimer's disease.

    abstract::The expression of neurodegenerative diseases can be categorized into three main symptomatic domains: neurological, cognitive and, neuropsychiatric. This review focuses on the cognitive profile and neuropsychological assessment of Alzheimer's disease (AD). The topography and progression of brain neuropathology determin...

    journal_title:Archives of medical research

    pub_type: 杂志文章,评审

    doi:10.1016/j.arcmed.2012.08.015

    authors: Peña-Casanova J,Sánchez-Benavides G,de Sola S,Manero-Borrás RM,Casals-Coll M

    更新日期:2012-11-01 00:00:00

  • Yeast exoglucanases. Where redundancy implies necessity.

    abstract::Three exoglucanase genes have been described in Saccharomyces cerevisiae. The bulk of the exoglucanase (EXO) activity is encoded by the EXG1 gene, whose primary gene product is differentially glycosylated during its transit to the cell surface to yield three isoenzymes: EXOI, EXOII and EXOII1/2. EXOII, the major isoen...

    journal_title:Archives of medical research

    pub_type: 杂志文章,评审

    doi:

    authors: Larriba G,Basco RD,Andaluz E,Luna-Arias JP

    更新日期:1993-10-01 00:00:00

  • Mysterious Virus: A Review on Behavior and Treatment Approaches of the Novel Coronavirus, 2019-nCoV.

    abstract::At the end of the year 2019, the novel coronavirus (2019-nCoV) was spreading in Wuhan, China, and the outbreak process has a high speed. It was recognized as a pandemic by the World Health Organization (WHO) on 11 March 2020. Coronaviruses are enveloped and single-stranded RNA that have several families including Seve...

    journal_title:Archives of medical research

    pub_type: 杂志文章,评审

    doi:10.1016/j.arcmed.2020.04.022

    authors: Hemmati F,Saedi S,Hemmati-Dinarvand M,Zarei M,Seghatoleslam A

    更新日期:2020-07-01 00:00:00

  • Apolipoprotein B (APOB) gene polymorphism in patients with gallbladder disease.

    abstract::Cholelithiasis is one of the most prevalent gastroenterological diseases, precipitated mainly by environmental factors. However, twin studies provided strong evidence for a role of genetic factors in the disease pathogenesis. An association between plasma lipoprotein levels and gallstone disease (GSD) was presented. A...

    journal_title:Archives of medical research

    pub_type: 杂志文章

    doi:10.1016/j.arcmed.2006.11.003

    authors: Kurzawski M,Juzyszyn Z,Modrzejewski A,Pawlik A,Wiatr M,Czerny B,Adamcewicz R,Droździk M

    更新日期:2007-04-01 00:00:00

  • Syndrome of Inappropriate Antidiuretic Hormone Secretion: A Poor Prognosis in Small-cell Lung Cancer.

    abstract:BACKGROUND AND AIMS:Small cell lung cancer (SCLC) is frequently associated with syndrome of inappropriate antidiuretic hormone (SIADH) secretion. In this study we investigated the prognostic value of SIADH in Chinese patients with SCLC. METHODS:We prospectively studied a total of 385 patients with SCLC diagnosed in ou...

    journal_title:Archives of medical research

    pub_type: 杂志文章

    doi:10.1016/j.arcmed.2015.12.006

    authors: Wang X,Liu M,Zhang L,Ma K

    更新日期:2016-01-01 00:00:00

  • Contemporary Applications of Fecal Microbiota Transplantation to Treat Intestinal Diseases in Humans.

    abstract::The intestinal microbiota comprise an important organ that plays a vital role in host digestion, development, energy maintenance, hemostasis, and immunity. Disruption of the gut microbial community due to diet, lifestyle, or antibiotic exposure increases susceptibility to chronic infection and disease. Fecal microbiot...

    journal_title:Archives of medical research

    pub_type: 杂志文章,评审

    doi:10.1016/j.arcmed.2017.11.006

    authors: Staley C,Khoruts A,Sadowsky MJ

    更新日期:2017-11-01 00:00:00

  • Polymorphism C1114G of gene encoding the cardiac regulator of G-protein signaling 2 may be associated with number of episodes of neurally mediated syncope.

    abstract:BACKGROUND AND AIMS:The cardiac regulator of G-protein signaling 2 (RGS2) negatively regulates G-protein-coupled receptor signaling. The C1114G polymorphism reduces RGS2 gene expression. This molecular disorder may be one of the important factors influencing progress of neurally mediated syncope. The aim of the study w...

    journal_title:Archives of medical research

    pub_type: 杂志文章

    doi:10.1016/j.arcmed.2009.02.005

    authors: Lelonek M,Pietrucha T,Matyjaszczyk M,Goch JH

    更新日期:2009-04-01 00:00:00

  • Detection of Molluscum contagiosum virus (MCV) subtype I as a single dominant virus subtype in Molluscum lesions from a Turkish population.

    abstract:BACKGROUND:Molluscum contagiosum has a worldwide occurrence and its primary mode of transmission is via direct human contact including sexual means. The aim of the study was to implement a polymerase chain reaction-based assay for detection and subtyping of Molluscum contagiosum virus (MCV) in skin lesions diagnosed wi...

    journal_title:Archives of medical research

    pub_type: 杂志文章

    doi:10.1016/j.arcmed.2005.05.020

    authors: Saral Y,Kalkan A,Ozdarendeli A,Bulut Y,Doymaz MZ

    更新日期:2006-04-01 00:00:00

  • ARID5B, CEBPE and PIP4K2A Germline Genetic Polymorphisms and Risk of Childhood Acute Lymphoblastic Leukemia in Mexican Patients: A MIGICCL Study.

    abstract:BACKGROUND AND AIMS:Childhood acute lymphoblastic leukemia (ALL) is the leading cause of childhood cancer-related deaths worldwide. Multiples studies have shown that ALL seems to be originated by an interaction between environmental and genetic susceptibility factors. The ARID5B polymorphisms are among the most reprodu...

    journal_title:Archives of medical research

    pub_type: 杂志文章

    doi:10.1016/j.arcmed.2016.12.003

    authors: Bekker-Méndez VC,Núñez-Enríquez JC,Torres Escalante JL,Alvarez-Olmos E,González-Montalvoc PM,Jiménez-Hernández E,Sansón AM,Leal YA,Ramos-Cervantes MT,Guerra-Castillo FX,Ortiz-Maganda MP,Flores-Lujano J,Pérez-Saldivar ML,Velazqu

    更新日期:2016-11-01 00:00:00

  • Distortion product otoacoustic emissions test is useful in children undergoing cisplatin treatment.

    abstract:BACKGROUND:Cisplatin is a widely used chemotherapy agent that has several adverse effects, such as ototoxicity. Evaluation of hearing loss due to cisplatin therapy in children is difficult. The purpose of this study was to compare the validity of distortion product otoacoustic emissions (DPOAEs) with pure tone audiomet...

    journal_title:Archives of medical research

    pub_type: 杂志文章

    doi:10.1016/S0188-4409(03)00022-5

    authors: Toral-Martiñón R,Shkurovich-Bialik P,Collado-Corona MA,Mora-Magaña I,Goldgrub-Listopad S,Shkurovich-Zaslavsky M

    更新日期:2003-05-01 00:00:00

  • Network between main protagonists and events leading to AIDS.

    abstract::A definitive single hypothesis about HIV pathogenesis is still lacking in specialized literature. Rather, a picture of the extreme complexity in AIDS causality ensues from the extensive information available. This article contains an outline of the most relevant data on the subject of AIDS pathogenesis, organized into...

    journal_title:Archives of medical research

    pub_type: 杂志文章,评审

    doi:

    authors: Larralde C,Huerta L

    更新日期:1996-07-01 00:00:00

  • Risk factors for osteoporotic hip fractures in Mexicans.

    abstract:BACKGROUND:Osteoporosis (OP) and its fractures are a major problem due to their impact in morbidity and mortality in the elderly. Although this entity is well studied in other countries, OP and its fractures have not been evaluated carefully in our population. The objective was to assess risk factors for osteoporotic h...

    journal_title:Archives of medical research

    pub_type: 杂志文章

    doi:

    authors: Clark P,de la Peña F,Gómez García F,Orozco JA,Tugwell P

    更新日期:1998-10-01 00:00:00

  • Contemporary treatment and outcomes of zygomycosis in a non-oncologic tertiary care center.

    abstract:BACKGROUND:Zygomycosis is an emerging mycosis of increasing relevance. Limited data exist for outcomes with contemporary therapies. METHODS:A 6-year retrospective chart review was performed in a non-oncological tertiary care center for patients with zygomycosis. RESULTS:Sixteen episodes of proven (EORTC/MSG criteria)...

    journal_title:Archives of medical research

    pub_type: 杂志文章

    doi:10.1016/j.arcmed.2006.06.009

    authors: Sims CR,Ostrosky-Zeichner L

    更新日期:2007-01-01 00:00:00

  • Discrimination between epidemiological cycles of rabies in Mexico.

    abstract:BACKGROUND:The design of efficient rabies control programs within a geographic area requires an appropriate knowledge of the local epidemiological cycles. In Latin America, there is a geographical overlap of the two main epidemiological cycles: (a) the terrestrial cycle, where the dog is the main terrestrial vector and...

    journal_title:Archives of medical research

    pub_type: 杂志文章

    doi:10.1016/s0188-0128(98)00019-0

    authors: Loza-Rubio E,Aguilar-Setién A,Bahloul C,Brochier B,Pastoret PP,Tordo N

    更新日期:1999-03-01 00:00:00

  • Association of Vitamin D Receptor Gene Polymorphisms and the Risk of Multiple Sclerosis: A Meta Analysis.

    abstract:BACKGROUND:Previous studies have reported vitamin D receptor (VDR) polymorphisms in multiple sclerosis (MS); however, the results remain contradictory. This study aimed to investigate the association between VDR polymorphisms and the risk of MS. METHODS:PubMed and Embase databases were searched to obtain eligible stud...

    journal_title:Archives of medical research

    pub_type: 杂志文章,meta分析

    doi:10.1016/j.arcmed.2019.10.007

    authors: Zhang D,Wang L,Zhang R,Li S

    更新日期:2019-08-01 00:00:00

  • Mechanisms involved in the hypotensive effect of a kappa-opioid receptor agonist in hypertensive rats.

    abstract:BACKGROUND:It remains unclear whether the activation of kappa-opioid receptors has strong hypotensive effects under hypertensive condition, and the underlying mechanisms have not yet been investigated. Therefore, the present study is designed to use spontaneously hypertensive rats (SHR) to investigate the effects of a ...

    journal_title:Archives of medical research

    pub_type: 杂志文章

    doi:10.1016/j.arcmed.2007.04.009

    authors: Guo HT,Zhang RH,Huang LY,Li J,Liu YL,Bi H,Zhang QY,Wang YM,Sun X,Ma XL,Cheng L,Liu JC,Yu SQ,Yi DH,Pei JM

    更新日期:2007-10-01 00:00:00

  • DNA damage and repair in lymphoblastoid cell lines from normal donors and fragile X syndrome patients.

    abstract:BACKGROUND:Because lymphocytes from fragile X patients have been reported as hypersensitive to bleomycin-induced chromatid breaks and because the number of trinucleotide repeats in families with fragile X syndrome has a propensity to expand, we have investigated the possibility that fragile X cells may be hypersensitiv...

    journal_title:Archives of medical research

    pub_type: 杂志文章

    doi:10.1016/s0188-4409(01)00376-9

    authors: Wang TS,Hsieh LJ,Hsu TY,Chung CH,Li SY

    更新日期:2002-03-01 00:00:00

  • Growth deficits in children with sickle cell disease.

    abstract:BACKGROUND:Growth deficits are common in children with sickle cell disease. Few prospective studies are available and the pathophysiologic basis for the impaired growth is not clearly understood. Our objectives were to collect data on anthropomorphic measurements of children with sickle cell disease prospectively follo...

    journal_title:Archives of medical research

    pub_type: 杂志文章

    doi:10.1016/s0188-4409(01)00360-5

    authors: Silva CM,Viana MB

    更新日期:2002-05-01 00:00:00

  • Prevalence of dyslipidemia in non-obese prepubertal children and its association with family history of diabetes, high blood pressure, and obesity.

    abstract:BACKGROUND:Because obesity masks the need for screening, there is no previous description of dyslipidemia in healthy normal-weight children. The aims of this study were a) to determine the prevalence of disorders in lipid profile among non-obese prepubertal children, and b) to establish its association with the family ...

    journal_title:Archives of medical research

    pub_type: 杂志文章

    doi:10.1016/j.arcmed.2006.06.003

    authors: Guerrero-Romero F,Rodríguez-Morán M

    更新日期:2006-11-01 00:00:00

  • Induction of macrophage killing of Leishmania donovani by human CD4+ T cell clones.

    abstract::Immunity in leishmaniasis is mediated by T cells, but protective responses in humans have not been fully defined. In this study, the functional activity of CD4+ T cell clones derived from an immune individual was investigated to identify potentially protective responses. The T cells proliferated and produced interfero...

    journal_title:Archives of medical research

    pub_type: 杂志文章

    doi:

    authors: Melby PC,Valencia-Pacheco G,Andrade-Narváez F

    更新日期:1996-01-01 00:00:00

  • Anemia in children with and without Helicobacter pylori infection.

    abstract:BACKGROUND:Iron deficiency is the most common cause of anemia in children. Recently there has been evidence to suggest a relationship between Helicobacter pylori gastritis and iron deficiency anemia. Because both H. pylori infection and iron-deficiency anemia are common in children, we studied any correlation between H...

    journal_title:Archives of medical research

    pub_type: 杂志文章

    doi:10.1016/j.arcmed.2008.04.005

    authors: Haghi-Ashtiani MT,Monajemzadeh M,Motamed F,Mahjoub F,Sharifan M,Shahsiah R,Kashef N

    更新日期:2008-07-01 00:00:00

  • Associations for lipoprotein lipase and peroxisome proliferator-activated receptor-gamma gene and coronary artery disease in an Indian population.

    abstract:BACKGROUND AND AIMS:Peroxisome proliferator activated receptor-gamma (PPARgamma) and lipoprotein lipase (LPL) genes are important in pathways of triglyceride metabolism, insulin resistance and adipogenesis. We hypothesized that polymorphisms of PPARgamma Pro12Ala, LPL HindIII and LPL Ser447X influence severity of coron...

    journal_title:Archives of medical research

    pub_type: 杂志文章

    doi:10.1016/j.arcmed.2010.01.005

    authors: AshokKumar M,Veera Subhashini NG,Kanthimathi S,SaiBabu R,Ramesh A,Cherian KM,Emmanuel C

    更新日期:2010-01-01 00:00:00

  • Prognostic Significance of Serum CD26 Concentration in Patients with Esophageal Squamous Cell Carcinoma.

    abstract:BACKGROUND:Esophageal squamous cell carcinoma (ESCC) is one of the most common cancers in developing countries. The aim of the study was to determine the association between serum CD26 concentration and outcome of patients with ESCC. METHODS:A total of 183 patients with ESCC and 254 healthy controls were selected. Blo...

    journal_title:Archives of medical research

    pub_type: 杂志文章

    doi:10.1016/j.arcmed.2016.07.005

    authors: Xinhua W,Xiangting Q,Lingling C,Guohong L

    更新日期:2016-05-01 00:00:00