Venous ulcer: epidemiology, physiopathology, diagnosis and treatment.

Abstract:

:This review discusses the epidemiology, pathogenesis, diagnosis and current therapeutic options for venous ulcer. Venous ulcer is a severe clinical manifestation of chronic venous insufficiency (CVI). It is responsible for about 70% of chronic ulcers of the lower limbs. The high prevalence of venous ulcer has a significant socioeconomic impact in terms of medical care, days off work and reduced quality of life. Long-term therapeutics are needed to heal venous ulcers and recurrence is quite common, ranging from 54 to 78%. Thrombophlebitis and trauma with long-term immobilization predisposing to deep venous thrombosis are important risk factors for CVI and venous ulcer. The most recent theories about pathogenesis of venous ulcer have associated it with microcirculatory abnormalities and generation of an inflammatory response. Management of venous leg ulcers is based on understanding the pathogenesis. In recent years novel therapeutic approaches for venous ulcers have offered valuable tools for the management of patients with this disorder.

journal_name

Int J Dermatol

authors

Abbade LP,Lastória S

doi

10.1111/j.1365-4632.2004.02456.x

subject

Has Abstract

pub_date

2005-06-01 00:00:00

pages

449-56

issue

6

eissn

0011-9059

issn

1365-4632

pii

IJD2456

journal_volume

44

pub_type

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