Compatibility of intraocular lenses with blood and connective tissue cells measured by cellular deposition and inflammatory response in vitro.

Abstract:

:Injection molded poly(methyl methacrylate) (IM-PMMA), lathe-cut PMMA (LC-PMMA), heparin surface modified PMMA (HSM-PMMA), silicone, and polyhydroxyethyl methacrylate (polyHEMA) intraocular lenses (IOLs) were incubated with platelets, granulocytes, mouse macrophage-like RAW 264.7 cells and mouse fibrosarcoma L929 cells to examine their compatibility. The number of cells attached to the IOL was counted after the central IOL area (0.04 mm2) was photographed with an inverted light microscope. Cell morphology was examined by scanning electron microscopy (SEM). More platelets and granulocytes were attached to the IM-PMMA and silicone IOLs than to the HSM-PMMA and polyHEMA IOLs (P less than .05). RAW 264.7 and L929 cells grew on PMMA-based and silicone IOLs, whereas HSM-PMMA and polyHEMA IOLs did not support an abundant growth of these cells. Granulocytes were incubated with the IOLs in the presence of Luminol and the generation of chemiluminescence was measured. Poly(methyl methacrylate)-based IOLs caused granulocytes to release significant amounts of oxygen radicals, while the polyHEMA IOL was almost inactive in stimulating granulocytes. Silicone and HSM-PMMA IOLs showed an intermediate level of stimulating activity. The light intensity reached a peak within 14 minutes with the IM-PMMA IOL, and in about 18 minutes with the other IOLs. Our results suggest that IOL hydrophilicity prevents attachment of cells and that a hydrophilic, soft surface can discourage granulocyte stimulation.

authors

Joo CK,Kim JH

doi

10.1016/s0886-3350(13)80900-5

subject

Has Abstract

pub_date

1992-05-01 00:00:00

pages

240-6

issue

3

eissn

0886-3350

issn

1873-4502

pii

S0886-3350(13)80900-5

journal_volume

18

pub_type

杂志文章
  • Toxic anterior segment inflammation following cataract surgery.

    abstract::Cataract extraction with posterior chamber intraocular lens implantation is rarely complicated by an acute, sterile, anterior segment inflammation. We report three unrelated cases of acute intraocular inflammation following uncomplicated cataract extraction and posterior chamber intraocular lens placement. A constella...

    journal_title:Journal of cataract and refractive surgery

    pub_type: 杂志文章

    doi:10.1016/s0886-3350(13)80929-7

    authors: Monson MC,Mamalis N,Olson RJ

    更新日期:1992-03-01 00:00:00

  • Computer-animated model of accommodation and presbyopia.

    abstract:PURPOSE:To understand, demonstrate, and further research the mechanisms of accommodation and presbyopia. SETTING:Private practice, Little Silver, New Jersey, USA. DESIGN:Experimental study. METHODS:The CAMA 2.0 computer-animated model of accommodation and presbyopia was produced in collaboration with an experienced ...

    journal_title:Journal of cataract and refractive surgery

    pub_type: 杂志文章

    doi:10.1016/j.jcrs.2014.07.028

    authors: Goldberg DB

    更新日期:2015-02-01 00:00:00

  • Uveal and capsular biocompatibility of a single-piece, sharp-edged hydrophilic acrylic intraocular lens with collagen (Collamer): 1-year results.

    abstract:PURPOSE:To analyze uveal and capsular biocompatibility 1 year following implantation of a sharp-edged, hydrophilic, collagen-containing posterior chamber intraocular lens (IOL). SETTING:Department of Ophthalmology, University of Vienna Medical School, Vienna, Austria. METHOD:In a prospective study, a Collamer CC4204B...

    journal_title:Journal of cataract and refractive surgery

    pub_type: 杂志文章

    doi:10.1016/j.jcrs.2003.11.041

    authors: Schild G,Amon M,Abela-Formanek C,Schauersberger J,Bartl G,Kruger A

    更新日期:2004-06-01 00:00:00

  • Interlenticular opacification: dual-optic versus piggyback intraocular lenses.

    abstract:PURPOSE:To evaluate and compare the incidence of capsular bag opacification, particularly interlenticular opacification (ILO), in rabbit eyes implanted with a dual-optic silicone intraocular lens (IOL) or piggyback lenses. SETTING:John A. Moran Eye Center, University of Utah, Salt Lake City, Utah, USA. METHODS:Ten du...

    journal_title:Journal of cataract and refractive surgery

    pub_type: 杂志文章

    doi:10.1016/j.jcrs.2006.01.022

    authors: Werner L,Mamalis N,Stevens S,Hunter B,Chew JJ,Vargas LG

    更新日期:2006-04-01 00:00:00

  • Implantation of a multifocal toric intraocular lens with a surface-embedded near segment after repeated LASIK treatments.

    abstract:UNLABELLED:We report a 66-year-old patient who presented with increasing hyperopia, astigmatism, and presbyopia in both eyes 8 years after bilateral laser in situ keratomileusis (LASIK) and LASIK enhancement in the left eye aiming for spectacle independence. Bilateral multifocal toric Lentis Mplus intraocular lenses (I...

    journal_title:Journal of cataract and refractive surgery

    pub_type: 杂志文章

    doi:10.1016/j.jcrs.2012.08.042

    authors: Khoramnia R,Auffarth GU,Rabsilber TM,Holzer MP

    更新日期:2012-11-01 00:00:00

  • Impact of high and low aspiration parameters on postoperative outcomes of phacoemulsification: randomized clinical trial.

    abstract:PURPOSE:To compare the effects of fluidic parameters on the central corneal thickness (CCT), corneal endothelium, and anterior segment inflammation after phacoemulsification with longitudinal ultrasound. SETTING:Iladevi Cataract & IOL Research Center, Ahmedabad, India. METHODS:In this prospective randomized patient- ...

    journal_title:Journal of cataract and refractive surgery

    pub_type: 杂志文章,随机对照试验

    doi:10.1016/j.jcrs.2009.11.009

    authors: Vasavada AR,Praveen MR,Vasavada VA,Vasavada VA,Raj SM,Asnani PK,Garg VS

    更新日期:2010-04-01 00:00:00

  • Formula choice: Hoffer Q, Holladay 1, or SRK/T and refractive outcomes in 8108 eyes after cataract surgery with biometry by partial coherence interferometry.

    abstract:PURPOSE:To assess how intraocular lens (IOL) formula choice affects refractive outcomes after cataract surgery using IOLMaster biometry. SETTING:Department of Ophthalmology, Gloucestershire Hospitals NHS Foundation Trust, Cheltenham, United Kingdom. DESIGN:Database study. METHODS:Hypothetical prediction errors were ...

    journal_title:Journal of cataract and refractive surgery

    pub_type: 杂志文章

    doi:10.1016/j.jcrs.2010.07.032

    authors: Aristodemou P,Knox Cartwright NE,Sparrow JM,Johnston RL

    更新日期:2011-01-01 00:00:00

  • Posterior chamber toric phakic intraocular lens implantation for high myopic astigmatism in eyes with pellucid marginal degeneration.

    abstract:UNLABELLED:We report a case in which toric intraocular Collamer lenses (ICLs) effectively corrected the refractive errors of pellucid marginal degeneration (PMD). Preoperatively, in the patient's right eye, the manifest refraction was -10.5 -3.5 x 55, the uncorrected distance visual acuity (UDVA) was 20/1000, and the c...

    journal_title:Journal of cataract and refractive surgery

    pub_type: 杂志文章

    doi:10.1016/j.jcrs.2009.08.021

    authors: Kamiya K,Shimizu K,Hikita F,Komatsu M

    更新日期:2010-01-01 00:00:00

  • Comparison of function and fixation of small incision circular and oval poly(methyl methacrylate) intraocular lenses.

    abstract::A prospective study of function and fixation was done on 40 patients implanted with small incision poly(methyl methacrylate), single piece, biconvex intraocular lenses after in situ phacoemulsification cataract extraction via a continuous curvilinear capsulorhexis. A 5.0 mm circular optic (Pharmacia 740 P), 14 mm leng...

    journal_title:Journal of cataract and refractive surgery

    pub_type: 杂志文章

    doi:10.1016/s0886-3350(13)80919-4

    authors: Davis PL

    更新日期:1992-03-01 00:00:00

  • Detection of integrins in cataract lens epithelial cells.

    abstract:PURPOSE:To detect the expression of integrin subunits in lens epithelial cells (LECs) of human cataracts. SETTING:Research Laboratory, International Intraocular Implant Training Centre, Tianjin Medical University, China. METHODS:The circular sections of the anterior capsules with attached LECs were obtained during ca...

    journal_title:Journal of cataract and refractive surgery

    pub_type: 杂志文章

    doi:10.1016/s0886-3350(99)00369-7

    authors: Zhang XH,Ji J,Zhang H,Tang X,Sun HM,Yuan JQ

    更新日期:2000-02-01 00:00:00

  • Vitrectorhexis and lens aspiration with posterior chamber intraocular lens implantation in spherophakia.

    abstract:UNLABELLED:We describe a technique that uses the vitrector to perform successful lens aspiration and posterior chamber intraocular lens (IOL) implantation in children with spherophakia and anterior lens subluxation. After an anterior chamber maintainer is placed, the ocutome is introduced through a limbal incision to p...

    journal_title:Journal of cataract and refractive surgery

    pub_type: 杂志文章

    doi:10.1016/j.jcrs.2012.05.001

    authors: Al-Haddad C,Khatib L

    更新日期:2012-07-01 00:00:00

  • Contrast sensitivity measured by 2 methods after photorefractive keratectomy.

    abstract:PURPOSE:To study contrast sensitivity in eyes that had flying-spot excimer laser photorefractive keratectomy (PRK) and to compare a subjective method (Vision Contrast Test System [VCTS] 6500) and an objective method (visual evoked potential [VEP]) of measuring contrast sensitivity. SETTING:Istituto Clinica Oculistica,...

    journal_title:Journal of cataract and refractive surgery

    pub_type: 杂志文章

    doi:10.1016/s0886-3350(00)00405-3

    authors: Vetrugno M,Quaranta GM,Maino A,Mossa F,Cardia L

    更新日期:2000-06-01 00:00:00

  • Comparability and repeatability of corneal astigmatism measurements using different measurement technologies.

    abstract:PURPOSE:To determine the comparability and repeatability of corneal astigmatism measurements obtained with different devices and determine the interobserver variability of a new automated keratometer. SETTING:University Eye Clinic Maastricht, the Netherlands. DESIGN:Prospective cohort study. METHODS:The right eye of...

    journal_title:Journal of cataract and refractive surgery

    pub_type: 杂志文章

    doi:10.1016/j.jcrs.2012.05.036

    authors: Visser N,Berendschot TT,Verbakel F,de Brabander J,Nuijts RM

    更新日期:2012-10-01 00:00:00

  • Results and methodology of cost-utility evaluation of cataract surgery in developed countries: Quality-adjusted life years and cataract.

    abstract::This review surveyed the results and methods of cost-utility analyses of cataract surgery. Thirteen studies were included. Based on decision-theoretic time trade-off, utilities ranged from 0.148 to 0.8 and quality-adjusted life years (QALY) ranged from 1.424 to 2.43. Based on psychometric instruments such as Euroqol 5...

    journal_title:Journal of cataract and refractive surgery

    pub_type: 杂志文章,评审

    doi:10.1016/j.jcrs.2017.05.020

    authors: Hahn U,Krummenauer F

    更新日期:2017-06-01 00:00:00

  • Subjective photic phenomena with refractive multifocal and monofocal intraocular lenses. results of a multicenter questionnaire.

    abstract:PURPOSE:To compare the incidence and severity of photic phenomena after the implantation of the Array(R) (Allergan) refractive multifocal intraocular lens (MIOL) and a monofocal IOL. SETTING:Multicenter study at Kiel, Mainz, Karlsruhe, and Bremerhaven, Germany. METHODS:The study comprised 231 randomly selected patien...

    journal_title:Journal of cataract and refractive surgery

    pub_type: 临床试验,杂志文章,多中心研究,随机对照试验

    doi:10.1016/s0886-3350(00)00540-x

    authors: Häring G,Dick HB,Krummenauer F,Weissmantel U,Kröncke W

    更新日期:2001-02-01 00:00:00

  • Correcting simple myopic astigmatism with the excimer laser.

    abstract::For one year we followed 46 eyes that had photoastigmatic refractive keratectomy with an excimer laser to correct simple myopic astigmatism. Mean preoperative cylinder was -2.50 +/- 0.70 diopters (D); mean preoperative best corrected visual acuity was 20/25 +/- 1 Snellen line. Mean postoperative refraction one year af...

    journal_title:Journal of cataract and refractive surgery

    pub_type: 杂志文章

    doi:10.1016/s0886-3350(13)80207-6

    authors: Alió JL,Artola A,Ayala MJ,Claramonte P

    更新日期:1995-09-01 00:00:00

  • Cyclotorsional eye motion occurring between wavefront measurement and refractive surgery.

    abstract:PURPOSE:To quantify the cyclorotation occurring between wavefront measurement and laser refractive surgery. SETTING:LaserVue Eye Center Ophthalmic Clinic, Santa Rosa, California, USA. METHODS:The pupil camera of the Visx WaveScan wavefront device was used to obtain images of 51 eyes (26 patients) from 5 to 20 minutes...

    journal_title:Journal of cataract and refractive surgery

    pub_type: 杂志文章

    doi:10.1016/j.jcrs.2003.08.022

    authors: Chernyak DA

    更新日期:2004-03-01 00:00:00

  • Collagen crosslinking with ultraviolet-A and hypoosmolar riboflavin solution in thin corneas.

    abstract::Corneal collagen crosslinking (CXL) with riboflavin and ultraviolet-A light is a method for treating progressive keratectasia. The currently accepted treatment parameters induce collagen crosslinking in the anterior 250 to 350 microm of corneal stroma. To protect the endothelium, CXL inclusion criteria require a minim...

    journal_title:Journal of cataract and refractive surgery

    pub_type: 杂志文章

    doi:10.1016/j.jcrs.2008.10.060

    authors: Hafezi F,Mrochen M,Iseli HP,Seiler T

    更新日期:2009-04-01 00:00:00

  • Spontaneous dislocation into the vitreous of a poly(methyl methacrylate) disc lens 9 years after surgery.

    abstract::A 76-year-old woman had sudden visual loss 9 years after an extracapsular cataract extraction with implantation of a poly(methyl methacrylate) disc intraocular lens (IOL) in the capsular bag. Slitlamp examination showed the disc IOL had luxated into the vitreous through a linear inferior opening in the capsular bag; t...

    journal_title:Journal of cataract and refractive surgery

    pub_type: 杂志文章

    doi:10.1016/s0886-3350(99)80142-4

    authors: Tognetto D,Agolini G,Ravalico G

    更新日期:1999-02-01 00:00:00

  • Deep anterior lamellar keratoplasty for keratectasia after laser in situ keratomileusis.

    abstract:PURPOSE:To assess the efficacy of deep anterior lamellar keratoplasty (DALK) for treating post-LASIK keratectasia. SETTING:Poostchi Eye Research Center, Shiraz University of Medical Sciences, Shiraz, Iran. DESIGN:Retrospective interventional cases series. METHODS:The same surgeon performed all DALK procedures using ...

    journal_title:Journal of cataract and refractive surgery

    pub_type: 杂志文章

    doi:10.1016/j.jcrs.2014.04.029

    authors: Salouti R,Nowroozzadeh MH,Makateb P,Zamani M,Ghoreyshi M,Melles GR

    更新日期:2014-12-01 00:00:00

  • Traumatic aniridia and aphakia after Artisan intraocular lens implantation.

    abstract::Traumatic aniridia and aphakia occurred in the left eye of a 22-year-old man who had had Artisan (Ophtec) phakic intraocular lens (IOL) implantation. Aniridia was probably the result of the relatively large wound used to implant the nonfoldable IOL. Although the eye had severe traumatic damage, vision was recoverable ...

    journal_title:Journal of cataract and refractive surgery

    pub_type: 杂志文章

    doi:10.1016/j.jcrs.2007.03.037

    authors: Lee SJ

    更新日期:2007-07-01 00:00:00

  • Management of a dislocated intraocular lens with a suction-based grasping tool.

    abstract:UNLABELLED:Spontaneous late subluxation of an intraocular lens (IOL) is a rare but serious complication of cataract surgery, often associated with poor zonular support. The management of this complication with a conventional forceps is difficult because the forceps often cannot adequately grasp the optic or haptic to f...

    journal_title:Journal of cataract and refractive surgery

    pub_type: 杂志文章

    doi:10.1016/j.jcrs.2012.12.004

    authors: Olson JL,Velez-Montoya R,Erlanger M,Mackenzie D

    更新日期:2013-02-01 00:00:00

  • Factors related to corneal endothelial damage after phacoemulsification in eyes with occludable angles.

    abstract:PURPOSE:To evaluate the influence of preoperative variables and early postoperative intraocular pressure (IOP) on the loss of corneal endothelial cells after phacoemulsification in eyes with occludable angles. SETTING:Taipei Veterans General Hospital, Taipei, Taiwan. METHODS:Sixty patients with occludable angles havi...

    journal_title:Journal of cataract and refractive surgery

    pub_type: 杂志文章

    doi:10.1016/j.jcrs.2007.07.057

    authors: Ko YC,Liu CJ,Lau LI,Wu CW,Chou JC,Hsu WM

    更新日期:2008-01-01 00:00:00

  • Posterior continuous curvilinear capsulorhexis and optic capture of the intraocular lens to prevent secondary opacification in pediatric cataract surgery.

    abstract:PURPOSE:To evaluate the safety and efficacy of posterior continuous curvilinear capsulorhexis with optic capture n preventing secondary opacification of the visual axis in pediatric eyes having cataract surgery and intraocular lens (IOL) implantation. SETTING:Gimbel Eye Centre, Calgary, Alberta, Canada. METHOD:Poster...

    journal_title:Journal of cataract and refractive surgery

    pub_type: 杂志文章

    doi:10.1016/s0886-3350(97)80049-1

    authors: Gimbel HV

    更新日期:1997-01-01 00:00:00

  • Comparison of effective phacoemulsification time and corneal endothelial cell loss using 2 ultrasound frequencies.

    abstract:PURPOSE:To compare 2 ultrasound (US) frequencies for phacoemulsification for moderate to hard cataract to determine a frequency that makes phacoemulsification safer and more efficacious. SETTING:Post Graduate Institute of Medical Education and Research, New Delhi, India. DESIGN:Randomized controlled trial. METHODS:P...

    journal_title:Journal of cataract and refractive surgery

    pub_type: 杂志文章,随机对照试验

    doi:10.1016/j.jcrs.2019.04.015

    authors: Dewan T,Malik PK,Kumari R

    更新日期:2019-09-01 00:00:00

  • Corneal collagen crosslinking with riboflavin and ultraviolet A to treat induced keratectasia after laser in situ keratomileusis.

    abstract:PURPOSE:To determine whether riboflavin and ultraviolet-A (UVA) corneal crosslinking can be used as an alternative therapy to prevent the progression of keratectasia. SETTING:Institute for Refractive and Ophthalmic Surgery, Zurich, Switzerland, and a private clinic, Athens, Greece. METHODS:Corneal crosslinking was pe...

    journal_title:Journal of cataract and refractive surgery

    pub_type: 杂志文章

    doi:10.1016/j.jcrs.2007.07.028

    authors: Hafezi F,Kanellopoulos J,Wiltfang R,Seiler T

    更新日期:2007-12-01 00:00:00

  • Intraocular recombinant tissue-plasminogen activator fibrinolysis of fibrin formation after cataract surgery in children.

    abstract:PURPOSE:To evaluate the efficacy and safety of intracameral recombinant tissue plasminogen activator (rt-PA) application for fibrinolysis of fibrin formation after cataract surgery in children. SETTING:Johann Wolfgang Goethe-University, Department of Ophthalmology, Frankfurt am Main, Germany. METHODS:This study compr...

    journal_title:Journal of cataract and refractive surgery

    pub_type: 临床试验,杂志文章

    doi:10.1016/s0886-3350(99)80083-2

    authors: Klais CM,Hattenbach LO,Steinkamp GW,Zubcov AA,Kohnen T

    更新日期:1999-03-01 00:00:00

  • Entry of antibiotic ointment into the anterior chamber after uneventful phacoemulsification.

    abstract::A 77-year-old woman had uneventful phacoemulsification. Postoperative examination revealed that chloramphenicol ointment instilled in the conjunctival fornix had entered the anterior chamber and smeared the intraocular lens (IOL). Immediate surgical removal of the ointment with IOL exchange was performed. The eye sett...

    journal_title:Journal of cataract and refractive surgery

    pub_type: 杂志文章

    doi:10.1016/s0886-3350(02)01503-1

    authors: Aralikatti AK,Needham AD,Lee MW,Prasad S

    更新日期:2003-03-01 00:00:00

  • Corneal chromoblastomycosis caused by Cladophialophora carrionii after cataract surgery.

    abstract::We describe a case of corneal chromoblastomycosis with Cladophialophora carrionii in a 69-year-old woman 4 weeks after clear corneal cataract surgery. The patient presented with right eye pain and decreased visual acuity of 20/100. Examination showed a deep posterior stromal keratitis accompanied by a dense fibrinous ...

    journal_title:Journal of cataract and refractive surgery

    pub_type: 杂志文章

    doi:10.1016/j.jcrs.2011.03.007

    authors: Lari HB,Mirani N,Chu DS

    更新日期:2011-05-01 00:00:00

  • Wavefront aberrometry: comparing and profiling higher-order aberrations produced by intraocular lenses in vitro using a physical model eye system and Hartman-Shack aberrometry.

    abstract:PURPOSE:To characterize and compare the higher-order aberrations (HOAs) in 3 intraocular lenses (IOLs) designed to minimize HOAs using a new physical model eye. SETTING:Department of Ophthalmology, University of Auckland, New Zealand. METHODS:Measurements of higher-order wavefront aberrations were obtained using the ...

    journal_title:Journal of cataract and refractive surgery

    pub_type: 杂志文章

    doi:10.1016/j.jcrs.2008.11.048

    authors: McKelvie J,Ku JY,McArdle B,McGhee C

    更新日期:2009-03-01 00:00:00