Abstract:
:Traditional medicines in the form of botanical dietary supplements and nutraceuticals have found a place in 21st century healthcare. They nonetheless all contain compounds that are foreign to humans (i.e. xenobiotics) and that are subject to the same pharmacological issues encountered by synthetic therapeutic agents. It is crucial therefore for all parties, the medical profession, investigative scientists, the regulatory agencies and the public, to understand the particular characteristics of botanicals and nutraceuticals and their potential for success and failure in preventing and confronting disease.
journal_name
Curr Opin Plant Bioljournal_title
Current opinion in plant biologyauthors
Barnes S,Prasain Jdoi
10.1016/j.pbi.2005.03.010subject
Has Abstractpub_date
2005-06-01 00:00:00pages
324-8issue
3eissn
1369-5266issn
1879-0356pii
S1369-5266(05)00042-7journal_volume
8pub_type
杂志文章,评审abstract::Plants have acquired the ability for organized multicellular development independent from animals. Because of this, they represent an independent example in nature for the development of coordinated, complex cell polarity from the simple polarity found in unicellular eukaryotes. Plants display a striking array of pola...
journal_title:Current opinion in plant biology
pub_type: 杂志文章,评审
doi:10.1016/j.pbi.2008.09.009
更新日期:2009-02-01 00:00:00
abstract::High-throughput DNA sequencing and genotyping technologies have enabled a new generation of research in plant genetics where combined quantitative and population genetic approaches can be used to better understand the relationship between naturally occurring genotypic and phenotypic diversity. Forest trees are highly ...
journal_title:Current opinion in plant biology
pub_type: 杂志文章,评审
doi:10.1016/j.pbi.2007.12.004
更新日期:2008-04-01 00:00:00
abstract::Acylsugars are insecticidal plant specialized metabolites produced in the Solanaceae (nightshade family). Despite having simple constituents, these compounds are unusually structurally diverse. Their structural variations in phylogenetically closely related species enable comparative biochemical approaches to understa...
journal_title:Current opinion in plant biology
pub_type: 杂志文章,评审
doi:10.1016/j.pbi.2019.03.005
更新日期:2019-06-01 00:00:00
abstract::Plants must adapt to drought stress to survive. The phytohormone abscisic acid (ABA) is produced under drought stress conditions and is essential for the response to drought stress. The ABA level plays an important role in the response, and several enzymes for ABA biosynthesis and catabolism have been identified. Phys...
journal_title:Current opinion in plant biology
pub_type: 杂志文章,评审
doi:10.1016/j.pbi.2007.04.014
更新日期:2007-06-01 00:00:00
abstract::The combination of mutational and molecular studies has shed light on the role of reactive oxygen intermediates and programmed cell death in cereal disease resistance mechanisms. Rice Rac1 and barley Rar1 represent conserved disease resistance signalling genes, which may have related functions in animals. The analysis...
journal_title:Current opinion in plant biology
pub_type: 杂志文章,评审
doi:10.1016/S1369-5266(99)80052-1
更新日期:1999-08-01 00:00:00
abstract::Small RNAs, including microRNAs (miRNAs), small interfering RNAs (siRNAs), and trans-acting siRNAs (ta-siRNAs), mediate gene expression and epigenetic regulation. While siRNAs are highly diverged, miRNAs and ta-siRNAs are generally conserved but many are differentially expressed between related species and in interspe...
journal_title:Current opinion in plant biology
pub_type: 杂志文章,评审
doi:10.1016/j.pbi.2012.01.007
更新日期:2012-04-01 00:00:00
abstract::The lipid-derived hormone jasmonate (JA) regulates diverse aspects of plant immunity and development. Among the central components of the JA signaling cascade are the E3 ubiquitin ligase SCFCOI1 and Jasmonate ZIM-domain (JAZ) proteins that repress transcription of JA-responsive genes. Recent studies provide evidence t...
journal_title:Current opinion in plant biology
pub_type: 杂志文章,评审
doi:10.1016/j.pbi.2008.05.004
更新日期:2008-08-01 00:00:00
abstract::Recent years have seen considerable advances in our understanding of the particular physiological roles of the constituent enzymes of the tricarboxylic acid (TCA) cycle. Despite acquiring a fairly comprehensive overview of the functional importance of these proteins relatively little is known concerning how this impor...
journal_title:Current opinion in plant biology
pub_type: 杂志文章,评审
doi:10.1016/j.pbi.2013.01.004
更新日期:2013-06-01 00:00:00
abstract::Imprinting occurs in the endosperm of flowering plants. The endosperm, a product of central cell fertilization, is critical for embryo and seed development. Imprinting in the endosperm is mainly due to the inherited differences in gamete epigenetic composition. Studies have also shown that there are differences in gen...
journal_title:Current opinion in plant biology
pub_type: 杂志文章,评审
doi:10.1016/j.pbi.2011.02.006
更新日期:2011-04-01 00:00:00
abstract::Given the prevalence of duplicate genes and genomes in plant species, the study of their evolutionary dynamics has been a focus of study in plant evolutionary genetics over the past two decades. The past few years have been a particularly exciting time because recent theoretical and experimental investigations have le...
journal_title:Current opinion in plant biology
pub_type: 杂志文章,评审
doi:10.1016/j.pbi.2004.12.001
更新日期:2005-04-01 00:00:00
abstract::Transcription factors (TFs) are a group of proteins that control cellular processes by regulating the expression of downstream target genes. Recent progress has been made in the cloning and characterization of Arabidopsis TFs on the genome scale, especially on the cloning of open reading frames (ORFs), sequence analys...
journal_title:Current opinion in plant biology
pub_type: 杂志文章
doi:10.1016/j.pbi.2006.07.005
更新日期:2006-10-01 00:00:00
abstract::Recent progress in the genetic dissection of plant disease resistance signaling pathways has opened a number of new avenues towards engineering pathogen resistance in crops. Genes controlling race-specific and broad-spectrum resistance responses have been cloned, and novel induced resistance pathways have been identif...
journal_title:Current opinion in plant biology
pub_type: 杂志文章,评审
doi:10.1016/1369-5266(88)80058-x
更新日期:1998-08-01 00:00:00
abstract::Recent advances in the study of plant peroxisomes are shedding new light on the importance of these organelles for plant development, and are revealing similarities and differences in peroxisome protein import pathways between plants, animals and fungi. For example, the import of matrix proteins that carry the PTS1 an...
journal_title:Current opinion in plant biology
pub_type: 杂志文章,评审
doi:10.1016/j.pbi.2005.09.009
更新日期:2005-12-01 00:00:00
abstract::Active research in rice genetics aided by full-genome sequence has generated results to address multiple problems caused by biotic and abiotic stresses. The main challenges are achieving stability of resistance against variable biological agents and defining the genetic basis of traits influenced strongly by genotypex...
journal_title:Current opinion in plant biology
pub_type: 杂志文章,评审
doi:10.1016/j.pbi.2007.12.005
更新日期:2008-04-01 00:00:00
abstract::Paramutation describes both the process and results of trans-sensing between chromosomes that causes specific heritable changes in gene regulation. RNA molecules are implicated in mediating similar events in maize, mouse, and Drosophila. Changes in both small RNA profiles and cytosine methylation patterns in Arabidops...
journal_title:Current opinion in plant biology
pub_type: 杂志文章,评审
doi:10.1016/j.pbi.2012.09.003
更新日期:2012-11-01 00:00:00
abstract::Although concerted efforts to understand selected botanical models have been made, the resulting basic knowledge varies in its applicability to other diverse species including the major crops. Recent advances in high-throughput genomics are offering new avenues through which to exploit model systems for the study of b...
journal_title:Current opinion in plant biology
pub_type: 杂志文章,评审
doi:10.1016/s1369-5266(02)00246-7
更新日期:2002-04-01 00:00:00
abstract::The size of plant cells is determined by genetic, structural and physical factors as well as by internal and external signals. Our knowledge of the molecular mechanisms of these controls is still rudimentary. Recent studies indicate that ploidy level exerts an important control on cell size. By increasing ploidy, endo...
journal_title:Current opinion in plant biology
pub_type: 杂志文章,评审
doi:10.1016/s1369-5266(00)00118-7
更新日期:2000-12-01 00:00:00
abstract::During development, the behavior of cells in tissues is coordinated along specific orientations or directions by coordinating the polar localization of components in those cells. The coordination of such cell polarity is perhaps nowhere more spectacular than in developing leaves, where the polarity of hundreds of cell...
journal_title:Current opinion in plant biology
pub_type: 杂志文章,评审
doi:10.1016/j.pbi.2017.09.009
更新日期:2018-02-01 00:00:00
abstract::Signaling pathways in all organisms consist of series of phosphorylation and dephosphorylation events that define directionality and allow different levels of feedback-regulation. Mass spectrometry-based proteomic analyses in recent years have led to a proteome-wide identification of thousands of phosphorylation sites...
journal_title:Current opinion in plant biology
pub_type: 杂志文章,评审
doi:10.1016/j.pbi.2009.12.008
更新日期:2010-06-01 00:00:00
abstract::Medicago truncatula will be among the first plant species to benefit from the completion of a whole-genome sequencing project. For each of these species, Arabidopsis, rice and now poplar and Medicago, annotation, the process of identifying gene structures and defining their functions, is essential for the research com...
journal_title:Current opinion in plant biology
pub_type: 杂志文章,评审
doi:10.1016/j.pbi.2006.01.004
更新日期:2006-04-01 00:00:00
abstract::Virulence factors are molecules that enable plant pathogens to infect and colonize host tissues successfully. These molecules co-evolve with host genes to ensure functionality and to avoid recognition by the host immune system. Some pathogens also produce the plant growth hormone cytokinin (CK) and other plant hormone...
journal_title:Current opinion in plant biology
pub_type: 杂志文章,评审
doi:10.1016/j.pbi.2018.03.002
更新日期:2018-08-01 00:00:00
abstract::Among plant-microbe interactions, root nodule symbiosis is one of the most important beneficial interactions providing legume plants with nitrogenous compounds. Over the past years a number of genes required for root nodule symbiosis has been identified but most recently great advances have been made to dissect signal...
journal_title:Current opinion in plant biology
pub_type: 杂志文章,评审
doi:10.1016/j.pbi.2011.03.016
更新日期:2011-08-01 00:00:00
abstract::Pattern recognition receptors (PRRs) enable plants to sense non-self molecules displayed by microbes to mount proper defense responses or establish symbiosis. In recent years the importance of PRR subcellular trafficking to plant immunity has become apparent. PRRs traffic through the endoplasmatic reticulum (ER) and t...
journal_title:Current opinion in plant biology
pub_type: 杂志文章,评审
doi:10.1016/j.pbi.2012.05.004
更新日期:2012-08-01 00:00:00
abstract::Double fertilization in flowering seed plants requires intercellular signaling events between many interacting partners. The four cell types of the seven-celled female gametophyte communicate with each other to establish and maintain their identity. They secrete signaling molecules to guide the male gametophyte and to...
journal_title:Current opinion in plant biology
pub_type: 杂志文章,评审
doi:10.1016/j.pbi.2005.11.002
更新日期:2006-02-01 00:00:00
abstract::In plant innate immunity, the first line of microbial recognition leading to active defence responses relies on the perception of pathogen-associated molecular patterns (PAMPs) by pattern-recognition receptors (PRRs). This recognition leads to PAMP-triggered immunity (PTI). Despite the numerous PAMPs recognised by pla...
journal_title:Current opinion in plant biology
pub_type: 杂志文章,评审
doi:10.1016/j.pbi.2009.06.003
更新日期:2009-08-01 00:00:00
abstract::Nonhost resistance confers robust protection against pathogenic invaders, and has many similarities to host resistance. Through the different steps of pathogen development, plants make use of diverse defence strategies to present obstacles to the invader. These include preformed barriers, innate immunity in response t...
journal_title:Current opinion in plant biology
pub_type: 杂志文章,评审
doi:10.1016/s1369-5266(03)00063-3
更新日期:2003-08-01 00:00:00
abstract::Directional cell-to-cell transport of functional molecules, called polar transport, enables plants to sense and respond to developmental and environmental signals. Transporters that localize to plasma membranes (PMs) in a polar manner are key components of these systems. PIN-FORMED (PIN) auxin efflux carriers, which a...
journal_title:Current opinion in plant biology
pub_type: 杂志文章,评审
doi:10.1016/j.pbi.2017.06.012
更新日期:2017-12-01 00:00:00
abstract::The accumulation of a given element is a complex process controlled by a network of gene products critical for uptake, binding, transportation, and sequestration. Many of these genes and physiological processes affect more than one element. Therefore, to understand how elements are regulated, it is necessary to measur...
journal_title:Current opinion in plant biology
pub_type: 杂志文章,评审
doi:10.1016/j.pbi.2009.05.002
更新日期:2009-06-01 00:00:00
abstract::Gravitropism is the directional control of plant organ growth in response to gravity. Specialized gravity-sensing cells contain amyloplasts that can change their position according to the direction of gravity. Gravity signaling, which is elicited by the relocation of amyloplasts, is a key process that redirects auxin ...
journal_title:Current opinion in plant biology
pub_type: 杂志文章,评审
doi:10.1016/j.pbi.2019.07.005
更新日期:2019-12-01 00:00:00
abstract::The regulation of plant metabolic processes in response to environmental and developmental signals is a complex interaction between optimization of enzyme activity and transcriptional regulation of gene expression. Through painstaking efforts over more than 50 years, many metabolic pathways in plants have been charact...
journal_title:Current opinion in plant biology
pub_type: 杂志文章,评审
doi:10.1016/s1369-5266(03)00040-2
更新日期:2003-06-01 00:00:00