Efficacy of a physical therapy program in patients with Parkinson's disease: a randomized controlled trial.

Abstract:

OBJECTIVE:To investigate the effects of a physical therapy (PT) program in groups of people with Parkinson's disease (PD). DESIGN:Randomized controlled trial with a crossover design. SETTING:Two outpatient rehabilitation clinics in Boston and Amsterdam, respectively. PARTICIPANTS:Sixty-eight subjects diagnosed with typical, idiopathic PD, Hoehn and Yahr stage II or III, and stable medication use. INTERVENTION:Group A received PT and medication therapy (MT) for the first 6 weeks, followed by MT only for the second 6 weeks. Group B received only MT for the first 6 weeks and PT and MT for the second 6 weeks. MAIN OUTCOME MEASURES:The Sickness Impact Profile (SIP-68), the mobility portion of the SIP-68, the Unified Parkinson's Disease Rating Scale (UPDRS), and comfortable walking speed (CWS) at baseline, 6-week, 12-week, and 3-month follow-up. RESULTS:At 6 weeks, differences between groups were significant for the SIP mobility ( P =.015; effect size [ES]=.55), for CWS ( P =.012; ES=.49), for the activities of daily living (ADL) section of the UPDRS ( P =.014; ES=.45), and for the total UPDRS ( P =.007; ES=.56). The total SIP and the mentation and motor sections of the UPDRS did not differ significantly between groups. Significant differences were found at 3 months compared with baseline for CWS, the UPDRS ADL, and total scores. CONCLUSIONS:People with PD derive benefits in the short term from PT group treatment, in addition to their MT, for quality of life related to mobility, CWS, and ADLs; long-term benefits were found in CWS, UPDRS ADL, and total scores but varied between groups.

journal_name

Arch Phys Med Rehabil

authors

Ellis T,de Goede CJ,Feldman RG,Wolters EC,Kwakkel G,Wagenaar RC

doi

10.1016/j.apmr.2004.08.008

subject

Has Abstract

pub_date

2005-04-01 00:00:00

pages

626-32

issue

4

eissn

0003-9993

issn

1532-821X

pii

S0003-9993(04)01351-6

journal_volume

86

pub_type

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