Abstract：
:A few finite element models have addressed the dynamic juxtaarticular stress transmission but none focused the investigation on the combined influence of the individual moduli of the underlying bones, including the subchondral plate, the femoral head and the femoral neck of the proximal femur. A finite element model including the acetabulum and the proximal femur was analyzed with dynamic loadings to study the effects of mechanical property changes in the underlying bones of the proximal femur on the stress distribution in the cartilage at the hip joint. We found the stress distribution was most sensitive to the subchondral plate stiffening, while the overall stiffening of the underlying bones had mild effect on the shear stress on the cartilage surface (or at the subchondral bone/cartilage interface) and on the strain energy density in the cartilage. Our results indicate that the subchondral plate plays a predominant mechanical role in the initial degeneration of the cartilage. The results may offer a mechanical explanation as to why the cartilage failure is common in patients with osteoarthritis but rare in patients with osteoporosis.
journal_name
Med Eng Physjournal_title
Medical engineering & physicsauthors
Wei HW,Sun SS,Jao SH,Yeh CR,Cheng CKdoi
10.1016/j.medengphy.2004.12.008subject
Has Abstractpub_date
2005-05-01 00:00:00pages
295-304issue
4eissn
1350-4533issn
1873-4030pii
S1350-4533(05)00015-9journal_volume
27pub_type
杂志文章abstract：:This study describes the method of determination of the position and orientation of artificial knee implants using a single-plane radiograph. To simplify the 3D/2D matching problem, we proposed to use small markers embedded in a bone. From the image coordinates of markers, it is possible to estimate the position and o...
journal_title：Medical engineering & physics
pub_type： 杂志文章
doi：10.1016/s1350-4533(03)00037-7
更新日期：2003-06-01 00:00:00
abstract：:The formation of pressure ulcers can be exacerbated by a breakdown in the integrity of the patient's skin caused by poor maintenance of the skin microclimate. Patient support systems (PSSs-specialised beds, mattresses, chairs, cushions and pads) play an important role in the dissipation of heat and moisture away from ...
journal_title：Medical engineering & physics
pub_type： 杂志文章
doi：10.1016/s1350-4533(00)00003-5
更新日期：1999-12-01 00:00:00
abstract：:The acetabular cup (AC) is an implant impacted into a bone cavity and used for hip prosthesis surgery. Initial stability of the AC is an important factor for long term surgical success. The aim of this study is to determine the variations of the impact duration during AC implant insertion. Twenty-two bone samples take...
journal_title：Medical engineering & physics
pub_type： 杂志文章
doi：10.1016/j.medengphy.2013.04.005
更新日期：2013-11-01 00:00:00
abstract：:Ankle sprains are the most common sports injury. Gaining a better understanding of ankle mechanics will help improve current treatments, enabling a better quality of life for patients following surgery. In this paper, the development of a robotic system for ankle joint testing is presented. It is composed of an indust...
journal_title：Medical engineering & physics
pub_type： 杂志文章
doi：10.1016/j.medengphy.2018.10.002
更新日期：2018-12-01 00:00:00
abstract：:To reduce the time of computation of a motor unit potential (MUP), the shape of intracellular action potential (IAP) and (or) MU anatomy are generally simplified. A method of MUP presentation is suggested. It provides accuracy of the MUPs calculated for any distance and size of rectangular electrodes together with con...
journal_title：Medical engineering & physics
pub_type： 杂志文章
doi：10.1016/s1350-4533(98)00014-9
更新日期：1998-07-01 00:00:00
abstract：:Artificial blood pumps play an increasingly important role in the treatment of end-stage cardiac failure. The fluid dynamics of blood flow through such devices crucially affects their clinical effectiveness. Specifically, if the flow of blood stagnates or slowly re-circulates thrombus formation can occur and the avoid...
journal_title：Medical engineering & physics
pub_type： 杂志文章
doi：10.1016/s1350-4533(00)00023-0
更新日期：2000-04-01 00:00:00
abstract：:To determine the reliability, stability, validity and precision of a stereophotogrammetry (SP) system for use in quantifying the complex three-dimensional structure of the human torso, we performed assessments of the system using images of geometric solids and a human-form mannequin. Analysis of geometric solids revea...
journal_title：Medical engineering & physics
pub_type： 杂志文章
doi：10.1016/j.medengphy.2009.08.011
更新日期：2009-12-01 00:00:00
abstract：:The biomechanical strength of the skeleton, and hence the risk of future fractures, depends on both the bone quantity (assessed in terms of bone mineral density) and bone quality (assessed in terms of the integrity of its internal architecture). Precise methods of measuring the calcium-equivalent density of both the t...
journal_title：Medical engineering & physics
pub_type： 杂志文章
doi：10.1016/1350-4533(96)00011-2
更新日期：1996-10-01 00:00:00
abstract：:Hepatic venous pressure gradient (HVPG) is a hemodynamic index widely used for evaluating the severity of portal hypertension. Theoretically, HVPG can be measured in any of the three major (i.e., right, middle and left) hepatic veins (HVs); however, it remains unclear whether HVPGs measured in different HVs are exchan...
journal_title：Medical engineering & physics
pub_type： 杂志文章
doi：10.1016/j.medengphy.2020.07.022
更新日期：2020-10-01 00:00:00
abstract：:Neointimal hyperplasia (NIH) is a major obstacle to graft patency in the peripheral arteries. A complex interaction of biomechanical factors contribute to NIH development and progression, and although haemodynamic markers such as wall shear stress have been linked to the disease, these have so far been insufficient to...
journal_title：Medical engineering & physics
pub_type： 杂志文章
doi：10.1016/j.medengphy.2019.09.011
更新日期：2019-12-01 00:00:00
abstract：:Small spaces make collision-free turns difficult for wheelchair users. Contrary to basic kinematic wheelchair modelling and not considered previously by engineers; when wheelchairs turn in small spaces, could lateral drift (sideways slipping) increase the risk of collisions with surrounding structures such as walls an...
journal_title：Medical engineering & physics
pub_type： 杂志文章
doi：10.1016/j.medengphy.2020.11.012
更新日期：2021-01-01 00:00:00
abstract：:In this paper, we present a novel decentralized robust methodology for control of quiet upright posture during arm-free paraplegic standing using functional electrical stimulation (FES). Each muscle-joint complex is considered as a subsystem and individual controllers are designed for each one. Each controller operate...
journal_title：Medical engineering & physics
pub_type： 杂志文章
doi：10.1016/j.medengphy.2011.06.013
更新日期：2012-01-01 00:00:00
abstract：BACKGROUND:Verified and validated CT-based high-order finite element (FE) methods were developed that predict accurately the mechanical response of patient-specific intact femurs. Here we extend these capabilities to human femurs undergoing a total hip replacement using cemented prostheses. METHODS:A fresh-frozen huma...
journal_title：Medical engineering & physics
pub_type： 杂志文章
doi：10.1016/j.medengphy.2012.09.007
更新日期：2013-07-01 00:00:00
abstract：:In this study, we applied multi-channel mechanomyographic (MMG) recordings in combination with linear and nonlinear analyses to investigate muscular and musculotendinous effects of high intensity eccentric exercise. Twelve accelerometers arranged in a 3 × 4 matrix over the dominant elbow muscles were used to detect MM...
journal_title：Medical engineering & physics
pub_type： 杂志文章
doi：10.1016/j.medengphy.2014.09.003
更新日期：2014-12-01 00:00:00
abstract：:Dynamic models of the human trunk have been extensively used to investigate the biomechanics of lower back pain and postural instability in different populations. Despite their diverse applications, previous models rely on intrinsic upper body segment parameters (UBSP), e.g., each segment's mass-inertia characteristic...
journal_title：Medical engineering & physics
pub_type： 杂志文章
doi：10.1016/j.medengphy.2010.09.008
更新日期：2011-01-01 00:00:00
abstract：:In vivo bone behaviour predictions with respect to altered loading conditions, implants, and endoprostheses are highly desirable to avoid untoward effects such as implant loosening and breakage. This knowledge does not relate only to the result but also to the mechanisms of bone adaptation and bone growth. Since bone ...
journal_title：Medical engineering & physics
pub_type： 杂志文章
doi：10.1016/1350-4533(94)90014-0
更新日期：1994-01-01 00:00:00
abstract：:A ligamentous, nonlinear, sliding contact, three-dimensional finite element (FE) model of L2-L3 complex was developed to investigate the biomechanical effect of laminectomy with and without facetectomy. The L2-L3 FE model was validated against experimental study under various physiological loadings and found to match ...
journal_title：Medical engineering & physics
pub_type： 杂志文章
doi：10.1016/j.medengphy.2003.11.006
更新日期：2004-04-01 00:00:00
abstract：OBJECTIVE:To illustrate (a) whether a statistical shape model (SSM) augmented with anatomical landmark set(s) performs better fitting and provides improved clinical relevance over non-augmented SSM and (b) which anatomical landmark set provides the best augmentation strategy for predicting the glenoid region of the sca...
journal_title：Medical engineering & physics
pub_type： 杂志文章
doi：10.1016/j.medengphy.2019.11.007
更新日期：2020-02-01 00:00:00
abstract：:Kinematic parameters for 10 normal subjects and 10 patients with ankle arthrodesis are grouped using the fuzzy cluster paradigm. The features chosen for clustering are Euler angles of the sagittal plane in the hindfoot, the forefoot and combined hindfoot and forefoot joints. Gait patterns are identified using informat...
journal_title：Medical engineering & physics
pub_type： 杂志文章
doi：10.1016/s1350-4533(01)00020-0
更新日期：2001-03-01 00:00:00
abstract：:Schlemm's canal (SC) is a ring structure responsible for maintaining fluid homeostasis in the anterior chamber of the eye by draining aqueous humor (AH) from the trabecular meshwork (TM) into the collecting channel (CC). Obstruction of the AH flow in this conventional pathway leads to an elevation of intraocular press...
journal_title：Medical engineering & physics
pub_type： 杂志文章
doi：10.1016/j.medengphy.2020.12.005
更新日期：2021-02-01 00:00:00
abstract：OBJECTIVE:Joint space narrowing is an important feature of progressive joint damage and functional impairment in rheumatoid arthritis (RA). Methods to provide a continuous measurement of joint space width have not been adopted in research or clinical settings. High-resolution peripheral quantitative computed tomography...
journal_title：Medical engineering & physics
pub_type： 杂志文章
doi：10.1016/j.medengphy.2013.04.003
更新日期：2013-10-01 00:00:00
abstract：:Clinical studies show that non-invasive respiratory support by continuous positive airway pressure (CPAP) affects gas conditioning in the upper airways, especially in the presence of mouth leaks. Using a new bench model of neonatal CPAP, we investigated the influence of mouth opening on oropharyngeal temperature and h...
journal_title：Medical engineering & physics
pub_type： 杂志文章
doi：10.1016/j.medengphy.2016.12.005
更新日期：2017-02-01 00:00:00
abstract：:For many decades correlation and power spectrum have been primary tools for digital signal processing applications in the biomedical area. The information contained in the power spectrum is essentially that of the autocorrelation sequence; which is sufficient for complete statistical descriptions of Gaussian signals o...
journal_title：Medical engineering & physics
pub_type： 杂志文章,评审
doi：10.1016/j.medengphy.2010.04.009
更新日期：2010-09-01 00:00:00
abstract：:In case of large segmental defects in load-bearing bones, an external fixator is used to provide mechanical stability to the defect site. The overall stiffness of the bone-fixator system is determined not only by the fixator design but also by the way the fixator is mounted to the bone. This stiffness is an important ...
journal_title：Medical engineering & physics
pub_type： 杂志文章
doi：10.1016/j.medengphy.2012.10.006
更新日期：2013-07-01 00:00:00
abstract：:The biomedical applications of wireless robots are an active area of study. In addition to moving to a target lesion, wireless locomotive robots can deliver a therapeutic drug for a specific disease. Thus, they hold great potential as therapeutic devices in blood vessel diseases, such as thrombi and occlusions, and in...
journal_title：Medical engineering & physics
pub_type： 杂志文章
doi：10.1016/j.medengphy.2016.01.001
更新日期：2016-04-01 00:00:00
abstract：:Biomagnetic investigations in basic physiological research using animals require measurement devices different from commercial biomagnetometers used in human investigations. Two major problems have to be tackled in the design of such biomagnetometers. First, the spatial sampling needs to be much higher. Second, the di...
journal_title：Medical engineering & physics
pub_type： 杂志文章
doi：10.1016/s1350-4533(99)00088-0
更新日期：1999-10-01 00:00:00
abstract：:The impeller blood pump with its simplicity has many advantages compared with the diaphragm pump, but the nonpulsatile property has limited its applications. To make the impeller pump pulsatile, many investigations have been made in vain because of resulting haemolysis. The author has succeeded in producing a pulsatil...
journal_title：Medical engineering & physics
pub_type： 杂志文章
doi：10.1016/1350-4533(95)00010-0
更新日期：1996-01-01 00:00:00
abstract：:The purpose of this study was to determine the use and feasibility of accelerometry-based monitoring and to examine a discrete multi-resolution signal analysis technique to determine motoric subtypes in patients with DSM-IV delirium. Forty consecutive patients receiving palliative care (23 male, 17 female, mean age+/-...
journal_title：Medical engineering & physics
pub_type： 临床试验,杂志文章
doi：10.1016/j.medengphy.2009.10.012
更新日期：2010-03-01 00:00:00
abstract：:Terahertz pulsed imaging is a spectroscopic imaging modality using pulses of electromagnetic radiation (100 GHz-10 THz), and there has been recent interest in studying biomedical specimens. It is usual to display parametric images derived from the measured pulses. In this work, classification was achieved by applying ...
journal_title：Medical engineering & physics
pub_type： 杂志文章
doi：10.1016/j.medengphy.2004.02.011
更新日期：2004-06-01 00:00:00
abstract：:The paper described a limited part of the coagulation pathway, and in particular the inhibitory effects of activated protein C in the context of thrombin production. This is a computational modeling study with various assumption made of kinetic rates laws and their summation. The level of complexity and assumed parame...
journal_title：Medical engineering & physics
pub_type： 杂志文章
doi：10.1016/j.medengphy.2004.01.003
更新日期：2004-05-01 00:00:00
