Microdermabrasion.

abstract：:Rituximab is a chimeric monoclonal antibody that selectively binds to the CD20 molecule on B cells, resulting in their lysis. In autoimmune blistering diseases, the auto-antibody-producing B cells are destroyed and auto-antibody levels are reduced or eliminated. In the majority of patients, rituximab produces rapid cl...

journal_title：American journal of clinical dermatology

authors： Ahmed AR,Shetty S

更新日期：2015-06-01 00:00:00

abstract：:There is a high unmet clinical need for new and better treatments in acne vulgaris. Propionibacterium acnes has a strong proinflammatory activity and targets molecules involved in the innate cutaneous immunity, keratinocytes and sebaceous glands of the pilosebaceous follicle. The role of P. acnes in acne confers legit...

journal_title：American journal of clinical dermatology

authors： Simonart T

更新日期：2013-12-01 00:00:00

abstract：:Erythema annulare centrifugum is a reactive erythema of various possible etiologies including, although less often, an associated cancer. Cancer-related erythema annulare centrifugum is most commonly associated with lymphoproliferative malignancies, specifically lymphoma and leukemia. Malignancy-associated erythema an...

journal_title：American journal of clinical dermatology

authors： Chodkiewicz HM,Cohen PR

更新日期：2012-08-01 00:00:00

abstract：:Radiation-recall dermatitis is the occurrence, with subsequent administration of cytotoxic chemotherapy, of an acute inflammatory toxicity in a previously quiescent radiation field. It may occur from days to weeks, and sometimes years, after the radiation therapy. The precise mechanism is unknown. One hypothesis sugge...

journal_title：American journal of clinical dermatology

authors： Yeo W,Johnson PJ

更新日期：2000-03-01 00:00:00

abstract：BACKGROUND:Botulinum toxin (BTX) is a potent neurotoxin with a long history of therapeutic application in neurological and dermatological conditions, with a strong efficacy and safety profile. OBJECTIVE:Our aim was to assess whether intradermal injection with BTX-B is an effective treatment for hidradenitis suppurativ...

journal_title：American journal of clinical dermatology

authors： Grimstad Ø,Kvammen BØ,Swartling C

更新日期：2020-10-01 00:00:00

abstract：:Aging of the skin is associated with skin thinning, atrophy, dryness, wrinkling, and delayed wound healing. These undesirable aging effects are exacerbated by declining estrogen levels in postmenopausal women. With the rise in interest in long-term postmenopausal skin management, studies on the restorative benefits th...

journal_title：American journal of clinical dermatology

authors： Shu YY,Maibach HI

更新日期：2011-10-01 00:00:00

abstract：:Acne vulgaris is one of the most common inflammatory dermatoses and is seen in both the hospital setting and in general practice. Multiple factors are involved in the pathophysiology of acne, including: an alteration in the pattern of keratinization within the pilosebaceous follicles resulting in comedone formation; a...

journal_title：American journal of clinical dermatology

authors： Layton AM

更新日期：2001-01-01 00:00:00

abstract：:Superficial mycoses are becoming increasingly resistant to current antifungal medications. As alternative therapeutic options are limited, the increasing frequency of reports of antifungal resistance is alarming. This epidemic parallels the rise of antibiotic resistance; however, the significance of this problem has y...

journal_title：American journal of clinical dermatology

authors： Gupta AK,Renaud HJ,Quinlan EM,Shear NH,Piguet V

更新日期：2020-12-22 00:00:00

abstract：:A rapidly increasing number of people visit dermatologists for the prevention and treatment of aging skin. Sun avoidance and sunscreen use are widely accepted strategies of primary prevention against photoaging. Convincing evidence shows that topical application of retinoids has an effect on reversing, at least partia...

journal_title：American journal of clinical dermatology

authors： Antoniou C,Kosmadaki MG,Stratigos AJ,Katsambas AD

更新日期：2010-01-01 00:00:00

abstract：BACKGROUND:Videodermatoscopy is a non-invasive technique that allows in vivo skin observation at high magnifications. OBJECTIVE:The goal of this study was to determine if videodermatoscopy enhances diagnostic capability beyond standard clinical observation in three series of patients: one group of patients with overt ...

journal_title：American journal of clinical dermatology

authors： Lacarrubba F,Dall'Oglio F,Rita Nasca M,Micali G

更新日期：2004-01-01 00:00:00

abstract：:Peroxisome proliferator-activated receptors (PPARs) are members of the nuclear receptor superfamily that regulate lipid, glucose, and amino acid metabolism. More recently, PPARs and corresponding ligands have been shown in skin and other organs to regulate important cellular functions, including cell proliferation and...

journal_title：American journal of clinical dermatology

authors： Sertznig P,Seifert M,Tilgen W,Reichrath J

更新日期：2008-01-01 00:00:00

abstract：BACKGROUND:The relationship between psoriasis and vitiligo has not been previously confirmed, and we therefore aimed to investigate this association. METHODS:We conducted a search of the MEDLINE and EMBASE electronic databases on 22 January 2018 for case-control, cross-sectional, and cohort studies examining the assoc...

journal_title：American journal of clinical dermatology

authors： Yen H,Chi CC

更新日期：2019-02-01 00:00:00

abstract：:Our ability to successfully treat patients with moderate to severe psoriasis has improved significantly over the last several years with the development of more targeted therapies. IL-17A, a member of the IL-17 family of interleukins, is involved in regulating the innate and adaptive immune systems and has been identi...

journal_title：American journal of clinical dermatology

authors： Canavan TN,Elmets CA,Cantrell WL,Evans JM,Elewski BE

更新日期：2016-02-01 00:00:00

abstract：:Aggressive digital papillary adenocarcinoma (ADPAC) is a rare cutaneous malignant tumor. We report on a 42-year-old man presenting with a nontender firm nodule on his right thumb that had been present for 3 years. The lesion clinically resembled an acquired digital fibrokeratoma, but was found to be an ADPAC after pat...

journal_title：American journal of clinical dermatology

authors： Chi CC,Kuo TT,Wang SH

更新日期：2007-01-01 00:00:00

abstract：:Childhood-onset psoriasis affects approximately one-third of the psoriatic population. Among many potential treatments of childhood psoriasis, biological agents are emerging as a valuable option in the management of this disease. In Europe, etanercept has recently been approved for children aged 8 years and over. Data...

journal_title：American journal of clinical dermatology

authors： Bard S,Torchia D,Schachner LA

更新日期：2010-01-01 00:00:00

abstract：BACKGROUND:5% topical minoxidil solution has been widely used to stimulate new hair growth and help stop hair loss in men with androgenetic alopecia (AGA). However, it is not convenient for patients to continue applying the solution twice daily on a regular basis. Tretinoin is known to increase the percutaneous absorpt...

journal_title：American journal of clinical dermatology

authors： Shin HS,Won CH,Lee SH,Kwon OS,Kim KH,Eun HC

更新日期：2007-01-01 00:00:00

abstract：:Systemic sclerosis is an extremely variable disease in its manifestations and consequently, treatment needs to be individualized depending on the specific problems that each patient has. Limited scleroderma patients have a prolonged duration of Raynaud's phenomenon and puffy fingers before they develop any skin thicke...

journal_title：American journal of clinical dermatology

authors： Steen VD

更新日期：2001-01-01 00:00:00

abstract：:Hyperhidrosis is a common and distressing condition involving increased production of sweat. A variety of treatment modalities are used to try to control or reduce sweating. Sweat is secreted by eccrine glands innervated by cholinergic fibers from the sympathetic nervous system. Primary hyperhidrosis most commonly aff...

journal_title：American journal of clinical dermatology

authors： Connolly M,de Berker D

更新日期：2003-01-01 00:00:00

abstract：:Alopecia areata (AA) is non-scarring hair loss resulting from an autoimmune disorder. Severity varies from patchy hair loss that often spontaneously resolves to severe and chronic cases that can progress to total loss of scalp and body hair. Many treatments are available; however, the efficacy of these treatments has ...

journal_title：American journal of clinical dermatology

authors： Gupta AK,Carviel J,Abramovits W

更新日期：2017-02-01 00:00:00

abstract：BACKGROUND:Probiotic, prebiotic, and synbiotic supplementation is becoming more prevalent nowadays. Clinical studies have demonstrated some of the medical benefits of probiotics, prebiotics, and synbiotics within dermatology but an evidence-based review of their effects in adults is needed. OBJECTIVE:The aim of this s...

journal_title：American journal of clinical dermatology

authors： Notay M,Foolad N,Vaughn AR,Sivamani RK

更新日期：2017-12-01 00:00:00

abstract：BACKGROUND:Cutaneous lichen planus (CLP) is an inflammatory dermatosis. Its chronic relapsing course and frequently spontaneous regression hamper the assessment of treatment effectiveness. OBJECTIVE:To evaluate the efficacy of available treatment modalities for CLP. DATA SOURCES:PubMed, Cochrane Central Register of C...

journal_title：American journal of clinical dermatology

authors： Atzmony L,Reiter O,Hodak E,Gdalevich M,Mimouni D

更新日期：2016-02-01 00:00:00

abstract：:Photochemotherapy with methoxsalen (8-methoxypsoralen) and long wavelength ultraviolet (UV) radiation (referred to as 'PUVA' for psoralen plus UVA) is commonly used to treat psoriasis and vitiligo. These vastly different diseases respond to the therapy by different mechanisms even though the immediate effects of the t...

journal_title：American journal of clinical dermatology

authors： Gasparro FP

更新日期：2000-11-01 00:00:00

abstract：:For nearly 50 years, thalidomide has struggled between success and controversy. After causing an epidemic of phocomelia and other birth defects during the 1960s, affecting thousands of neonates, thalidomide was used as a sedative in selective disorders including leprosy. The potent anti-inflammatory properties of thal...

journal_title：American journal of clinical dermatology

authors： Pelle MT,Werth VP

更新日期：2003-01-01 00:00:00

abstract：:The incidence of basal cell carcinoma is rapidly increasing and a number of treatment modalities are available. Treatment of basal cell carcinoma includes both surgical and nonsurgical approaches, some of which are traditional, and others experimental. The treatment modality utilized is dependent on both the tumor typ...

journal_title：American journal of clinical dermatology

authors： Kuijpers DI,Thissen MR,Neumann MH

更新日期：2002-01-01 00:00:00

abstract：:Autoimmune bullous diseases (AIBD), including pemphigus, bullous pemphigoid, epidermolysis bullosa acquisita, mucous membrane pemphigoid, and pemphigoid gestationis, pose significant therapeutic challenges, especially in pregnant and post-partum breastfeeding patients or those planning to conceive. Data on the safety ...

journal_title：American journal of clinical dermatology

authors： Kushner CJ,Concha JSS,Werth VP

更新日期：2018-06-01 00:00:00

abstract：:Vitamin D plays a key role in skeletal and cardiovascular disorders, cancers, central nervous system diseases, reproductive diseases, infections, and autoimmune and dermatological disorders. The two main sources of vitamin D are sun exposure and oral intake, including vitamin D supplementation and dietary intake. Mult...

journal_title：American journal of clinical dermatology

authors： Kechichian E,Ezzedine K

更新日期：2018-04-01 00:00:00

abstract：:Immunotherapy has revolutionized the treatment of melanoma. Targeting of the immune checkpoints cytotoxic T-lymphocyte-associated protein 4 and programmed cell death protein 1 has led to improved survival in a subset of patients. Unfortunately, the use of immune checkpoint inhibitors is associated with significant sid...

journal_title：American journal of clinical dermatology

authors： Rizk EM,Seffens AM,Trager MH,Moore MR,Geskin LJ,Gartrell-Corrado RD,Wong W,Saenger YM

更新日期：2020-02-01 00:00:00

abstract：:The treatment of cutaneous T cell lymphoma (CTCL), which includes mycosis fungoides and Sezary syndrome, has been in a state of continual change over recent decades, as new therapies are constantly emerging in the search for more effective treatments for the disease. However, prognosis and survival of patients with CT...

journal_title：American journal of clinical dermatology

authors： Apisarnthanarax N,Talpur R,Duvic M

更新日期：2002-01-01 00:00:00

abstract：BACKGROUND:Methotrexate (MTX) is an effective treatment for psoriasis but its use is limited by its toxicity. Folate supplementation can be used to reduce the adverse effects of MTX, though this may impact efficacy. The frequency of folic acid supplementation is not well characterized. PURPOSE:The objective of this st...

journal_title：American journal of clinical dermatology

authors： Al-Dabagh A,Davis SA,Kinney MA,Huang K,Feldman SR

更新日期：2013-06-01 00:00:00

abstract：:We report a typical case of hematidrosis in a Chinese girl who had experienced frequent bleeding episodes for more than 3 years. During hospitalization, spontaneous bleeding from her intact skin was witnessed by our staff on more than 20 occasions. Characteristically, bloody droplets from the intact skin contained all...

journal_title：American journal of clinical dermatology

authors： Wang Z,Yu Z,Su J,Cao L,Zhao X,Bai X,Zhan S,Wu T,Jin L,Zhou P,Ruan C

更新日期：2010-12-01 00:00:00