Abstract：
:Natural killer cell and cytotoxic T-cell lymphomas are frequently difficult to distinguish because they share many common features, and yet it is important to make an accurate diagnosis because their prognoses differ. We report an unusual case of a white man with a CD56-positive T-cell lymphoma in the ileum. The histologic pattern was characterized by angioinvasion and angiodestruction. Immunohistochemical staining showed positive reactions to CD3, CD8, CD43, CD45RO, CD56, and T-cell intracellular antigen-1, but negative reactions to CD4, CD5, CD20, CD23, and CD57. Epstein-Barr virus (EBV) was not detected by EBV-latent membrane protein staining and EBV polymerase chain reaction technique. The T-cell receptor gamma chain gene was rearranged. According to the World Health Organization classification, the absence of EBV excludes the diagnosis of extranodal natural killer/T-cell lymphoma, nasal type. However, the association of EBV with this lymphoma in white patients is not clear. Therefore, absence of EBV alone does not necessarily exclude nasal-type natural killer/T-cell lymphoma, particularly because the histologic pattern in this case is highly characteristic of this tumor.
journal_name
Arch Pathol Lab Medjournal_title
Archives of pathology & laboratory medicineauthors
Frank MC,Bono E,Sun Tdoi
10.1043/1543-2165(2005)129<527:AUCOPT>2.0.CO;2subject
Has Abstractpub_date
2005-04-01 00:00:00pages
527-30issue
4eissn
0003-9985issn
1543-2165pii
CR4022journal_volume
129pub_type
杂志文章abstract：:Accurate diagnosis of salivary gland tumors can be challenging because of the many diagnostic entities, the sometimes extensive morphologic overlap, and the rarity of most tumor types. Ancillary testing is beginning to ameliorate some of these challenges through access to newer immunohistochemical stains and fluoresce...
journal_title：Archives of pathology & laboratory medicine
pub_type： 杂志文章,评审
doi：10.5858/arpa.2016-0259-SA
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journal_title：Archives of pathology & laboratory medicine
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journal_title：Archives of pathology & laboratory medicine
pub_type： 杂志文章
doi：
更新日期：1977-01-01 00:00:00
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journal_title：Archives of pathology & laboratory medicine
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doi：
更新日期：1989-11-01 00:00:00
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journal_title：Archives of pathology & laboratory medicine
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journal_title：Archives of pathology & laboratory medicine
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journal_title：Archives of pathology & laboratory medicine
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journal_title：Archives of pathology & laboratory medicine
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doi：
更新日期：1997-07-01 00:00:00
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journal_title：Archives of pathology & laboratory medicine
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doi：
更新日期：1991-10-01 00:00:00
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journal_title：Archives of pathology & laboratory medicine
pub_type： 杂志文章,评审
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更新日期：1997-12-01 00:00:00
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journal_title：Archives of pathology & laboratory medicine
pub_type： 杂志文章
doi：
更新日期：1988-02-01 00:00:00
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journal_title：Archives of pathology & laboratory medicine
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doi：
更新日期：1992-03-01 00:00:00
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journal_title：Archives of pathology & laboratory medicine
pub_type： 杂志文章
doi：10.1043/0003-9985(2000)124<0894:SCTOUB>2.0.CO;2
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journal_title：Archives of pathology & laboratory medicine
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doi：10.1043/0003-9985(2002)126<0606:FPACTI>2.0.CO;2
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journal_title：Archives of pathology & laboratory medicine
pub_type： 杂志文章
doi：
更新日期：1998-05-01 00:00:00
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journal_title：Archives of pathology & laboratory medicine
pub_type： 杂志文章,评审
doi：10.1043/1543-2165(2007)131[1110:MSICAC]2.0.CO;2
更新日期：2007-07-01 00:00:00
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journal_title：Archives of pathology & laboratory medicine
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更新日期：2009-11-01 00:00:00
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journal_title：Archives of pathology & laboratory medicine
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pub_type： 共识发展会议,杂志文章
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journal_title：Archives of pathology & laboratory medicine
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doi：
更新日期：1977-11-01 00:00:00
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更新日期：2004-03-01 00:00:00
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journal_title：Archives of pathology & laboratory medicine
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journal_title：Archives of pathology & laboratory medicine
pub_type： 杂志文章
doi：
更新日期：1991-11-01 00:00:00
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更新日期：2006-05-01 00:00:00
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journal_title：Archives of pathology & laboratory medicine
pub_type： 杂志文章
doi：
更新日期：1988-03-01 00:00:00
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