Abstract：
:Three patients (ages 3, 5, and 8 years) with various forms of functionally univentricular heart lesions received a total cavopulmonary connection with an extracardiac conduit as a final reconstructive procedure. Failure of the Fontan circulation occurred immediately after surgery because of spontaneous closure of surgical fenestrations in two children and absent fenestration in one. As an emergency procedure, in all patients the conduit was perforated by transcatheter intervention in order to create a connection to the anatomical right atrium. Following balloon dilatation of the perforated conduit, in all three patients covered stent grafts were placed in the newly created defect to attain a reliable communication. Patency of the fenestration was demonstrated by angiogram and any leakage was ruled out. Cardiac output improved and severe pleural effusion and ascites subsided. Right-to-left shunt could be demonstrated by echocardiography at follow-up after 7 months (median) in all three patients. Oxygen saturation remained stable between 85 and 90%. These preliminary results suggest that stent graft fenestration can serve as a valuable tool in failing Fontan circulation, particularly in patients with an extracardiac conduit. Covered stents have the potential to reduce the acute risk of bleeding and they help to prevent early spontaneous closure of the newly created fenestration.
journal_name
Pediatr Cardioljournal_title
Pediatric cardiologyauthors
Michel-Behnke I,Luedemann M,Bauer J,Hagel KJ,Akintuerk H,Schranz Ddoi
10.1007/s00246-004-0693-6subject
Has Abstractpub_date
2005-01-01 00:00:00pages
93-6issue
1eissn
0172-0643issn
1432-1971journal_volume
26pub_type
杂志文章abstract：:Calculating pulmonary vascular resistance is important in many fields of medicine. Although the influence of hematocrit on calculated resistance has been known for many years, it is rare to find the appropriate corrections in published articles. This review discusses the relationship between viscosity and resistance a...
journal_title：Pediatric cardiology
pub_type： 杂志文章,评审
doi：10.1007/s00246-011-9954-3
更新日期：2011-06-01 00:00:00
abstract：:In the fetus, the cardiac neural crest gives rise to both the thymus and the conotruncus of the heart. In newborn screening for severe T-cell lymphopenia neonates with congenital heart defects may be detected. In this study, we investigated the occurrence of T-cell lymphopenia in neonates with or without 22q11.2 delet...
journal_title：Pediatric cardiology
pub_type： 杂志文章
doi：10.1007/s00246-020-02317-y
更新日期：2020-04-01 00:00:00
abstract：:Electrocardiograms (heart rate, QRS voltage, QRS axis in the frontal plane. Q-Tc interval) echocardiograms [left ventricular fractional shortening (LVFS); preejection period (PEP); PEP/left ventricular ejection time (PEP/LVET) ratio; end-diastolic left ventricular free wall and interventricular septum thickness; prese...
journal_title：Pediatric cardiology
pub_type： 杂志文章
doi：10.1007/BF02238495
更新日期：1991-01-01 00:00:00
abstract：:Kaposiform hemangioendothelioma (KH) is a rare tumor of vascular origin that commonly affects the cutaneous tissues of the extremities. It can, however, affect the abdomen, thorax, head, or neck. Compared with juvenile hemangiomas, which tend to regress, KH tumors are locally aggressive and usually persist. Associated...
journal_title：Pediatric cardiology
pub_type： 杂志文章
doi：10.1007/s00246-012-0280-1
更新日期：2013-01-01 00:00:00
abstract：:Hypertrophic cardiomyopathy (HCM) is a rare presenting feature of congenital disorder of glycosylation type Ia (CDG-Ia). We report two female siblings with CDG-Ia and cardiomyopathy. Patient no. 1 died at 12 days of age from cardiac rupture and tamponade, which has not previously been reported in CDG-Ia. The second pa...
journal_title：Pediatric cardiology
pub_type： 杂志文章
doi：10.1007/s00246-012-0214-y
更新日期：2012-06-01 00:00:00
abstract：:Thrombocytopenia can be a real challenge during cardiac surgery in children with cyanotic congenital heart disease. This report describes a 7-year-old girl with d-transposition of the great arteries, ventricular septal defect, pulmonary hypertension, chronic thrombocytopenia, polycythemia, and chronic renal impairment...
journal_title：Pediatric cardiology
pub_type： 杂志文章
doi：10.1007/s00246-012-0570-7
更新日期：2013-01-01 00:00:00
abstract：:With improvements in technology and surgical technique, pediatric cardiologists are challenging surgeons to close symptomatic ventricular septal defects (VSDs) in ever smaller patients. Although delaying surgery may facilitate operative repair, early intervention decreases the period of time these patients require the...
journal_title：Pediatric cardiology
pub_type： 杂志文章
doi：10.1007/s00246-007-9016-z
更新日期：2008-01-01 00:00:00
abstract：:This report describes an unusual case with tortuosity of the great vessels in a neonate who presented at birth with cyanosis. The diagnosis was made with magnetic resonance imaging (MRI), then confirmed by genetic analysis. ...
journal_title：Pediatric cardiology
pub_type： 杂志文章
doi：10.1007/s00246-009-9486-2
更新日期：2009-11-01 00:00:00
abstract：:Adult studies suggest a better functional outcome after aortic valve replacement with a pulmonary autograft compared with mechanical or homograft valves. Little is known about functional results after Ross surgery in growing children. This study reports formal exercise stress echocardiographic data from 26 pediatric R...
journal_title：Pediatric cardiology
pub_type： 杂志文章
doi：10.1007/s00246-012-0218-7
更新日期：2012-06-01 00:00:00
abstract：:Management of warfarin in pediatric patients remains a clinical challenge. Warfarin may be administered after congenital heart surgery, and the risks of morbidity can be high. Currently, no data exist to describe the initiation of warfarin and the risk factors for morbidity in post-congenital heart surgery patients. T...
journal_title：Pediatric cardiology
pub_type： 杂志文章
doi：10.1007/s00246-012-0351-3
更新日期：2012-12-01 00:00:00
abstract：:Magnetocardiographic mapping was performed on a 2-year-old boy who suffered from the Wolff-Parkinson-White syndrome in association with a complex congenital heart defect. The pre-excitation site was determined noninvasively from the measured cardiac magnetic fields. The location was in the same anatomic region as foun...
journal_title：Pediatric cardiology
pub_type： 杂志文章
doi：10.1007/BF02310333
更新日期：1995-01-01 00:00:00
abstract：:Warfarin dosing is challenging due to a multitude of factors affecting its pharmacokinetics (PK) and pharmacodynamics (PD). A novel personalised dosing algorithm predicated on a warfarin PK/PD model and incorporating CYP2C9 and VKORC1 genotype information has been developed for children. The present prospective, obser...
journal_title：Pediatric cardiology
pub_type： 杂志文章,随机对照试验
doi：10.1007/s00246-019-02215-y
更新日期：2019-12-01 00:00:00
abstract：:Left atrial isomerism includes a complex spectrum of cardiac and extracardiac anomalies. The records of all patients with left isomerism born during the period of 1973-2010 and treated at the Children's Hospital, Helsinki were reviewed. The short- and long-term outcomes were studied. The review included 38 patients (5...
journal_title：Pediatric cardiology
pub_type： 杂志文章
doi：10.1007/s00246-012-0184-0
更新日期：2012-04-01 00:00:00
abstract：:Pulmonary artery thrombosis in neonates occurs rarely. This report describes the case of a term infant with a pulmonary artery thrombosis presenting as persistent pulmonary hypertension of the newborn. The risk factors identified in the case included maternal diabetes and heterozygous factor V Leiden deficiency. The p...
journal_title：Pediatric cardiology
pub_type： 杂志文章
doi：10.1007/s00246-008-9349-2
更新日期：2009-05-01 00:00:00
abstract：:The aim of this study was to clarify the association of clinical characteristics of unexplained syncope with the outcome of the head-up tilt test (HUT) in children. A total of 47 patients with unexplained syncope were classified into two groups according to their outcomes of HUT: the positive response group and the ne...
journal_title：Pediatric cardiology
pub_type： 杂志文章
doi：10.1007/s00246-003-0513-4
更新日期：2004-07-01 00:00:00
abstract：:A neonate with pulmonary interstitial glycogenosis, pulmonary hypertension, and hypertrophic cardiomyopathy is described. The fatal outcome for this patient contrasts with the reported favorable prognosis associated with isolated pulmonary interstitial glycogenosis. To the authors' knowledge, the association of pulmon...
journal_title：Pediatric cardiology
pub_type： 杂志文章
doi：10.1007/s00246-012-0311-y
更新日期：2013-02-01 00:00:00
abstract：:Left atrial tumor, diagnosed as myxoma at first investigation, was later demonstrated to be a malignant fibrosarcoma with myxoid change. Myxoma should be diagnosed and managed carefully because of its wide range of histopathologic features. ...
journal_title：Pediatric cardiology
pub_type： 杂志文章
doi：10.1007/s002460010218
更新日期：2001-05-01 00:00:00
abstract：:Eighteen of 25 survivors of aortic valvotomy in infancy were reinvestigated by cross-sectional echocardiography a mean of 7.5 (2.3-13.4) years after surgery. They had been operated at a median age of 38 (5-330) days. At the follow-up examination the gradient across the aortic valve was 41 +/- 19 (15-85) mmHg and the e...
journal_title：Pediatric cardiology
pub_type： 杂志文章
doi：10.1007/BF00788221
更新日期：1992-01-01 00:00:00
abstract：:Fetal interventions have been performed for some congenital heart diseases. However, these procedures have not gained wide acceptance due to concerns about their efficacy and safety. The aim of this study was to report on a preliminary experience with fetal cardiac interventions in Brazil. Twenty-two cardiac intervent...
journal_title：Pediatric cardiology
pub_type： 杂志文章
doi：10.1007/s00246-013-0792-3
更新日期：2014-03-01 00:00:00
abstract：:Prior to initiation of a formal screening program, 30 % of patients referred for device closure of an atrial septal defect (ASD) at our institution had atrial septal anatomy which precluded ASD device closure. This resulted in inefficiencies in workflow, staff utilization, and inconvenience for families. Our objective...
journal_title：Pediatric cardiology
pub_type： 杂志文章
doi：10.1007/s00246-015-1135-3
更新日期：2015-08-01 00:00:00
abstract：:In 810 schoolchildren (aged 5-14 years) the prevalence of a grade 1-3/6 vibratory innocent heart murmur (VIHM) is 41%. Restricted to a grade 2 or 3 VIHM, the prevalence is 14%, decreasing from 21% in the age-class 5-6 years to 8% for children 13-14 years of age. The prevalence of a grade 3 VIHM is 1%. Together with a ...
journal_title：Pediatric cardiology
pub_type： 杂志文章
doi：10.1007/BF00798120
更新日期：1994-11-01 00:00:00
abstract：:We report our findings in the microscopic examination of the conduction system in four infants with glycogen storage disease, one of whom had adequate electrophysiologic studies. The electrophysiologic studies in the latter case showed P-A and A-H intervals at the lower limits of normal, but the H-V interval was just ...
journal_title：Pediatric cardiology
pub_type： 杂志文章
doi：10.1007/BF02265613
更新日期：1982-01-01 00:00:00
abstract：:This review examines the mechanism of estrogen signaling in cardiomyocytes, with an emphasis on mechanisms that might be important in cardioprotection. It investigates estrogen signaling mediated by the nuclear estrogen receptors alpha and beta and the G-protein-coupled receptor (GPR 30/GPER). Estrogen signaling via n...
journal_title：Pediatric cardiology
pub_type： 杂志文章,评审
doi：10.1007/s00246-010-9877-4
更新日期：2011-03-01 00:00:00
abstract：:Very young mammals have an impressive cardiac regeneration capacity. In contrast, cardiac regeneration is very limited in adult humans. The hearts of young children have a higher regenerative capacity compared with adults, as, for example, seen after surgical correction of an anomalous left coronary artery arising fro...
journal_title：Pediatric cardiology
pub_type： 杂志文章,评审
doi：10.1007/s00246-015-1120-x
更新日期：2015-04-01 00:00:00
abstract：:Adrenomedullin (ADM) is a vasoactive peptide with potent dilatory effects. We studied whether perioperative myocardial injury could be altered by the presence of ADM. Blood samples from 19 children with congenital heart disease undergoing surgical repair were collected at six time points: preoperative, on cardiopulmon...
journal_title：Pediatric cardiology
pub_type： 杂志文章
doi：10.1007/s002460010046
更新日期：2000-05-01 00:00:00
abstract：:The hypothesis that mild recurrent aortic obstruction produces subtle changes in ambulatory blood pressure was investigated by performing 24-hour monitoring on 11 postoperative coarctation patients. Patients (age 16.1 +/- 2.7 years) were compared with normal controls (age 15.7 +/- 2.5 years, n = 15). Surgery (end-to-e...
journal_title：Pediatric cardiology
pub_type： 杂志文章
doi：10.1007/BF00794187
更新日期：1995-07-01 00:00:00
abstract：:A rare case of isolated innominate artery arising from a left persistent arterial duct with a right aortic arch is presented. Of interest in this case is the retrograde flow in the left carotid system, the history of developmental delay, and the magnetic resonance image (MRI) brain findings suggestive of asymmetric vo...
journal_title：Pediatric cardiology
pub_type： 杂志文章
doi：10.1007/s00246-010-9739-0
更新日期：2010-10-01 00:00:00
abstract：:Various echocardiographic parameters are determined in the assessment and evaluation of a patent ductus arteriosus. In isolation, many of these parameters have a low sensitivity and specificity for ductal hemodynamic significance compared with ductal size. This study aimed to correlate various echocardiographic parame...
journal_title：Pediatric cardiology
pub_type： 杂志文章
doi：10.1007/s00246-013-0640-5
更新日期：2013-06-01 00:00:00
abstract：:A 2100-g neonate underwent a two-ventricular surgical repair of a right ventricle-dominant unbalanced atrioventricular septal defect associated with the heterotaxy syndrome and sinus node dysfunction. Postoperative congestive heart failure persisted despite bradycardia management by temporary ventricular pacing. Spect...
journal_title：Pediatric cardiology
pub_type： 杂志文章
doi：10.1007/s002469900446
更新日期：1999-05-01 00:00:00
abstract：:Combination of right and left ventricular outflow tracts obstruction is extremely rare. Neonates with combined aortic stenosis (AS) and pulmonary stenosis (PS) present in critical condition and required urgent treatment. The management approach is not well defined. We report five female neonates with combined AS and P...
journal_title：Pediatric cardiology
pub_type： 杂志文章
doi：10.1007/s00246-014-1000-9
更新日期：2014-12-01 00:00:00
