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Factors predicting long-term outcome after chronic benzodiazepine therapy.

Abstract：

:41 patients who took part in a withdrawal programme from long-term treatment with diazepam in a controlled clinical trial were followed up five years later. Assessments were made of outcome derived from clinical symptomatology, formal psychiatric diagnosis, psychotropic drug use and frequency of contact with both primary care and psychiatric services. Using discriminant function analysis it was found that better outcome was associated with younger patients, fewer symptoms at time of withdrawal and, more particularly, six months later, less personality disturbance, and longer duration of diazepam use before withdrawal. The implications are discussed with particular reference to policies for withdrawing benzodiazepines.

journal_name

J Affect Disord

journal_title

Journal of affective disorders

authors

Holton A,Riley P,Tyrer P

doi

10.1016/0165-0327(92)90109-j

subject

Has Abstract

pub_date

1992-04-01 00:00:00

pages

245-52

issue

4

eissn

0165-0327

issn

1573-2517

pii

0165-0327(92)90109-J

journal_volume

24

pub_type

杂志文章

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