Trace eyeblink conditioning in abstinent alcoholic individuals: effects of complex task demands and prior conditioning.

Abstract:

:Chronic misuse of alcohol affects an integrated neural circuit supporting the formation of associative memories acquired during eyeblink classical conditioning (R. McGlinchey-Berroth et al., 1995). The authors of this study investigated single-cue trace conditioning in amnesic and nonamnesic abstinent alcoholic individuals who either were or were not trained in a single-cue delay conditioning task. Overall, untrained alcoholic participants were severely impaired in acquisition, and alcoholic participants previously trained in single-cue delay conditioning performed similarly to untrained control participants. Individual performance in acquisition varied significantly within task but was relatively stable between the trace and delay tasks; there were nonamnesic and amnesic alcoholic participants who acquired responses at a normal rate in both delay and trace conditioning. The similarity of performances in delay and trace conditioning suggests a common source of impairment across both tasks.

journal_name

Neuropsychology

journal_title

Neuropsychology

authors

McGlinchey RE,Fortier CB,Capozzi SM,Disterhoft JF

doi

10.1037/0894-4105.19.2.159

subject

Has Abstract

pub_date

2005-03-01 00:00:00

pages

159-70

issue

2

eissn

0894-4105

issn

1931-1559

pii

2005-02351-003

journal_volume

19

pub_type

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