Abstract：
:An antifungal protein was isolated from the mushroom Tricholoma giganteum var. golden blessings. The protocol included ion exchange chromatography on DEAE-cellulose, affinity chromatography on Affi-gel blue gel, ion exchange chromatography on CM-cellulose, and gel filtration by fast protein liquid chromatography on Superdex 75. The antifungal protein, designated trichogin, was unadsorbed on DEAE-cellulose but was adsorbed on Affi-gel blue gel and CM-cellulose. It exhibited antifungal activity against Fusarium oxysporum, Mycosphaerella arachidicola and Physalospora piricola. Trichogin inhibited HIV-1 reverse transcriptase with an IC50 of 83 nM.
journal_name
Peptidesjournal_title
Peptidesauthors
Guo Y,Wang H,Ng TBdoi
10.1016/j.peptides.2004.11.009subject
Has Abstractpub_date
2005-04-01 00:00:00pages
575-80issue
4eissn
0196-9781issn
1873-5169pii
S0196-9781(04)00508-Xjournal_volume
26pub_type
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