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Peroperative depth of anaesthesia may influence postoperative opioid requirements.

Abstract：

BACKGROUND:Studies on monitoring the depth of anaesthesia have shown that with the use of these monitors the peroperative consumption of anaesthetics can be reduced. Studies have also indicated that the peroperative depth of anaesthesia may affect the postoperative course. The purpose of this study was to evaluate a possible relation between the depths of anaesthesia and the postoperative pain score and consumption of morphine. METHODS:We used middle latency auditory evoked potentials (MLAEPs) for monitoring the depth of anaesthesia. The study was prospective, observer blinded and included 50 women scheduled for elective abdominal hysterectomy. Anaesthesia was induced using propofol and remifentanil. Before leaving the recovery room the patients were provided with a programmed patient-controlled pump (PCA), which was only activated on demand. Auditory evoked potentials were registered from just before induction of anaesthesia and during the whole procedure, but the anaesthetist did not have access to the monitor. RESULTS:Fifty patients were included and seven were excluded. The remaining 43 patients were divided into two groups: Group High (n=12) with an AAI>28 for >5% of the registration time and Group Low (n=31) with an AAI>28 for <5% of the registration time. Group High had significantly higher morphine requirements in the recovery and activated the PCA-pump more frequently during the first 24 postoperative hours. CONCLUSION:The results indicate that the peroperative depth of anaesthesia may have effects on the postoperative analgesic requirements.

journal_name

Acta Anaesthesiol Scand

journal_title

Acta anaesthesiologica Scandinavica

authors

Henneberg SW,Rosenborg D,Weber Jensen E,Ahn P,Burgdorff B,Thomsen LL

doi

10.1111/j.1399-6576.2005.00598.x

subject

Has Abstract

pub_date

2005-03-01 00:00:00

pages

293-6

issue

3

eissn

0001-5172

issn

1399-6576

pii

AAS598

journal_volume

49

pub_type

临床试验,杂志文章

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