Abstract:
OBJECTIVE:To determine the incidence of off-label use of, abuse of, and dependence on prescription nicotine inhaler. DESIGN:Prospective telephone and internet interviews for six months. PARTICIPANTS:535 new inhaler users. MAIN OUTCOME:Structured interview about off-label use (that is, use of inhaler for non-cessation reasons or concurrent use of inhaler and cigarettes) and Diagnostic and statistical manual, fourth edition (DSM-IV) and International classification of diseases, 10th edition (ICD-10) criteria for abuse and dependence RESULTS:Although many used inhaler and cigarettes concurrently at some time (43-55%), few used inhaler for non-cessation reasons (4-9%) and few persisted in off label use (8-16%; 95% confidence interval (CI) 5% to 19%). No participant met ICD-10 criteria for harmful use/abuse (95% CI 0% to 3.3%). Eight subjects (1.4%) appeared to meet DSM-IV or ICD-10 criteria for dependence on inhaler, but none were found dependent in a clinical expert interview (95% CI 0% to 3.3%). CONCLUSIONS:Although transient concurrent use of inhaler and cigarettes often occurs, use for non-cessation reasons, abuse and dependence are rare.
journal_name
Tob Controljournal_title
Tobacco controlauthors
Hughes JR,Adams EH,Franzon MA,Maguire MK,Guary Jdoi
10.1136/tc.2004.008367subject
Has Abstractpub_date
2005-02-01 00:00:00pages
49-54issue
1eissn
0964-4563issn
1468-3318pii
14/1/49journal_volume
14pub_type
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