当前位置： SCI文献检索 > AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY期刊下所有文献 > Antenatal maternal administration of phenobarbital for the prevention of exchange transfusion in neonates with hemolytic disease of the fetus and newborn.

Antenatal maternal administration of phenobarbital for the prevention of exchange transfusion in neonates with hemolytic disease of the fetus and newborn.

Abstract：

OBJECTIVE:Hemolytic disease of the fetus and newborn infant (HDFN) can be associated with bilirubin encephalopathy, which is usually averted through neonatal exchange transfusions (EXT). However, EXT can be associated with significant procedure-related morbidity. We hypothesized that maternal oral administration of phenobarbital (PB) to women with HDFN would reduce the rate of EXT. STUDY DESIGN:Cases of HDFN from January 1985 to June 2003 were reviewed. All patients who underwent serial intrauterine transfusions (IUTs) for red cell alloimmunization were included. Patients were offered oral phenobarbital (30 mg 3 times a day) after their last IUT in an effort to enhance fetal hepatic maturity. Variables studied included gestational age and hemoglobin multiples of the median at first transfusion and delivery, peak neonatal bilirubin, need for exchange transfusion, and maternal PB administration. Multivariate regression analysis was applied to determine relative risks and 95% CIs. RESULTS:Seventy-one patients met study criteria; 29% of the neonates underwent EXT. The use of antenatal PB was associated with a decreased incidence of EXT, 9% versus 52% ( P < .01). After controlling for confounding variables, the relative risk for EXT after antenatal PB administration was 0.23 (95% CI: 0.06-0.76). CONCLUSION:Maternal administration of PB reduces the need for neonatal EXTs in HDFN.

journal_name

Am J Obstet Gynecol

journal_title

American journal of obstetrics and gynecology

authors

Trevett TN Jr,Dorman K,Lamvu G,Moise KJ Jr

doi

10.1016/j.ajog.2004.08.016

subject

Has Abstract

pub_date

2005-02-01 00:00:00

pages

478-82

issue

2

eissn

0002-9378

issn

1097-6868

pii

S000293780400938X

journal_volume

192

pub_type

杂志文章

相关文献

AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY文献大全
  • A comparison of visual analyses of intrapartum fetal heart rate tracings according to the new national institute of child health and human development guidelines with computer analyses by an automated fetal heart rate monitoring system.

    abstract：OBJECTIVES:The aim of this study was to compare the visual analyses of fetal heart rate tracings by observers according to recent National Institute of Child Health and Human Development interpretative guidelines both with each other and with those of a computerized fetal heart rate analysis and alerting system. STUDY...

    journal_title：American journal of obstetrics and gynecology

    pub_type： 杂志文章

    doi：10.1067/mob.2000.107665

    authors： Devoe L,Golde S,Kilman Y,Morton D,Shea K,Waller J

    更新日期：2000-08-01 00:00:00

  • Circulatory effects of magnesium sulfate in normotensive and renal hypertensive pregnant sheep.

    abstract：:We have studied the effects of magnesium sulfate (MgSO4) administration in chronically instrumented normotensive and hypertensive pregnant sheep. Animals of 90 to 144 days' gestation were divided in two groups; those with normotensive arterial pressure and those in which renovascular hypertension had been produced. Ou...

    journal_title：American journal of obstetrics and gynecology

    pub_type： 杂志文章

    doi：10.1016/0002-9378(77)90255-1

    authors： Dandavino A,Woods JR Jr,Murayama K,Brinkman CR 3rd,Assali NS

    更新日期：1977-04-01 00:00:00

  • The effects of an antihistamine and/or a glucocorticoid on the prolactin response to surgical procedures.

    abstract：:Prolactin (PRL) release in response to surgical stress has been demonstrated in a variety of species. Previous studies in rats indicate this response is blunted or blocked by pretreatment with either glucocorticoids or antihistamines. The present study was designed to investigate this phenomenon in man. Serum PRL leve...

    journal_title：American journal of obstetrics and gynecology

    pub_type： 临床试验,杂志文章,随机对照试验

    doi：10.1016/0002-9378(78)90769-x

    authors： Chapler FK,Sherman BM,Swanson JA

    更新日期：1978-10-15 00:00:00

  • Placental lipid peroxides and thromboxane are increased and prostacyclin is decreased in women with preeclampsia.

    abstract：OBJECTIVE:There is an imbalance of increased thromboxane and decreased prostacyclin in placentas of women with preeclampsia, but this may not be the only imbalance. There is also an abnormal increase in serum lipid peroxides in preeclamptic women. Lipid peroxides are toxic compounds that damage cells and inhibit prosta...

    journal_title：American journal of obstetrics and gynecology

    pub_type： 杂志文章

    doi：10.1016/s0002-9378(12)80017-2

    authors： Wang Y,Walsh SW,Kay HH

    更新日期：1992-10-01 00:00:00

  • Oxygen consumption in fetal lambs after maternal administration of sodium pentobarbital.

    abstract：:To determine whether anesthesia lowers fetal oxygen consumption, sodium pentobarbital (10 mg/kg) was given intravenously to seven chronically instrumented pregnant ewes (123 to 144 days' gestation). Oxygen consumption fell by 23% in association with a rise in fetal vascular PO2. Fetal breathing movements were abolishe...

    journal_title：American journal of obstetrics and gynecology

    pub_type： 杂志文章

    doi：10.1016/0002-9378(86)90628-9

    authors： Rurak DW,Taylor SM

    更新日期：1986-03-01 00:00:00

  • Carotid atherosclerosis in women with polycystic ovary syndrome: initial results from a case-control study.

    abstract：OBJECTIVE:Our purpose was to determine whether women with polycystic ovary syndrome have greater subclinical atherosclerosis as measured by carotid artery ultrasonography. STUDY DESIGN:Sixteen premenopausal women > or = 40 years old with a history of clinical polycystic ovary syndrome and a current total testosterone ...

    journal_title：American journal of obstetrics and gynecology

    pub_type： 杂志文章

    doi：10.1016/s0002-9378(96)70665-8

    authors： Guzick DS,Talbott EO,Sutton-Tyrrell K,Herzog HC,Kuller LH,Wolfson SK Jr

    更新日期：1996-04-01 00:00:00

  • Abnormal spinal curvature and its relationship to pelvic organ prolapse.

    abstract：OBJECTIVE:Intra-abdominal vector forces have been implicated in the development of genital prolapse. Because the normal spinal curvature appears to protect the pelvic cavity from direct upper abdominal forces, variations in spinal curvature may alter these vector forces and possibly potentiate the development of pelvic...

    journal_title：American journal of obstetrics and gynecology

    pub_type： 杂志文章,多中心研究

    doi：10.1067/mob.2000.111489

    authors： Mattox TF,Lucente V,McIntyre P,Miklos JR,Tomezsko J

    更新日期：2000-12-01 00:00:00

  • Nighttime delivery and risk of neonatal encephalopathy.

    abstract：OBJECTIVE:The objective of the study was to determine the relationship between nighttime delivery and neonatal encephalopathy (NE). STUDY DESIGN:The design of the study was a retrospective population-based cohort of 1,864,766 newborns at a gestation of 36 weeks or longer in California, 1999-2002. We determined the ris...

    journal_title：American journal of obstetrics and gynecology

    pub_type： 杂志文章

    doi：10.1016/j.ajog.2010.09.022

    authors： Wu YW,Pham TN,Danielsen B,Towner D,Smith L,Johnston SC

    更新日期：2011-01-01 00:00:00

  • Patterns of gestational weight gain and birthweight outcomes in the Eunice Kennedy Shriver National Institute of Child Health and Human Development Fetal Growth Studies-Singletons: a prospective study.

    abstract：BACKGROUND:Inadequate or excessive total gestational weight gain is associated with increased risks of small- and large-for-gestational-age births, respectively, but evidence is sparse regarding overall and trimester-specific patterns of gestational weight gain in relation to these risks. Characterizing the interrelati...

    journal_title：American journal of obstetrics and gynecology

    pub_type： 杂志文章,多中心研究

    doi：10.1016/j.ajog.2017.05.013

    authors： Pugh SJ,Albert PS,Kim S,Grobman W,Hinkle SN,Newman RB,Wing DA,Grantz KL

    更新日期：2017-09-01 00:00:00

  • A pilot study to evaluate the relative efficacy of endometrial biopsy and full curettage in making a diagnosis of endometriosis by the detection of endometrial nerve fibers.

    abstract：OBJECTIVE:The purpose of this study was to evaluate endometrial biopsy and curettage in detecting small nerve fibers in eutopic endometrium for diagnosis of endometriosis. STUDY DESIGN:Endometrial biopsies with precise, consistent technique and curettings were taken from 37 women (20 with endometriosis and 17 without ...

    journal_title：American journal of obstetrics and gynecology

    pub_type： 临床试验,杂志文章

    doi：10.1016/j.ajog.2007.04.032

    authors： Al-Jefout M,Andreadis N,Tokushige N,Markham R,Fraser I

    更新日期：2007-12-01 00:00:00

  • Epidemiology of gestational trophoblastic disease.

    abstract：:The epidemiology of gestational trophoblastic disease is not well understood. Methodologic problems with published reports limit the interpretation of incidence data, although the frequency of hydatidiform mole appears to be about one per 1000 pregnancies. No consistent temporal trends in rates of either hydatidiform ...

    journal_title：American journal of obstetrics and gynecology

    pub_type： 杂志文章,评审

    doi：10.1016/s0002-9378(84)90370-3

    authors： Grimes DA

    更新日期：1984-10-01 00:00:00

  • Pregnancy and parental leave among obstetrics and gynecology residents: results of a nationwide survey of program directors.

    abstract：BACKGROUND:The health and economic benefits of paid parental leave have been well-documented. In 2016, the American College of Obstetricians and Gynecologists released a policy statement about recommended parental leave for trainees; however, data on adoption of said guidelines are nonexistent, and published data on pa...

    journal_title：American journal of obstetrics and gynecology

    pub_type： 杂志文章

    doi：10.1016/j.ajog.2018.04.017

    authors： Hariton E,Matthews B,Burns A,Akileswaran C,Berkowitz LR

    更新日期：2018-08-01 00:00:00

  • Nitrous oxide amniodistention compared with fluid amniodistention reduces operation time while inducing no changes in fetal acid-base status in a sheep model for endoscopic fetal surgery.

    abstract：OBJECTIVE:Our purpose was to evaluate in a sheep model for endoscopic fetal surgery the impact of nitrous oxide-gas amniodistention compared with fluid amniodistention on duration of surgery, hemorrhagic events, and fetomaternal acid-base status. STUDY DESIGN:Pregnant ewes (n = 16) at 92 to 104 days of gestation (term...

    journal_title：American journal of obstetrics and gynecology

    pub_type： 杂志文章

    doi：10.1067/mob.2002.120482

    authors： Gratacós E,Wu J,Devlieger R,Bonati F,Lerut T,Vanamo K,Deprest JA

    更新日期：2002-03-01 00:00:00

  • Significance of multiparameter flow cytometric analysis of ovarian cancer.

    abstract：:A prospective flow cytometric examination of ovarian epithelial tumors was undertaken to further characterize aneuploid (including triploid and tetraploid) tumor cell populations according to expression of ovarian tumor antigen CA125 and to expression of class I (normally present in ovarian epithelium) and class II (n...

    journal_title：American journal of obstetrics and gynecology

    pub_type： 杂志文章

    doi：10.1016/0002-9378(88)90081-6

    authors： Fowler WC Jr,Maddock MB,Moore DH,Haskill S

    更新日期：1988-04-01 00:00:00

  • Histologic and hormonal documentation of the luteinized unruptured follicle syndrome.

    abstract：:Histologic and hormonal documentation of a luteinized unruptured follicle that occurred during a spontaneous menstrual cycle in a rhesus monkey is presented. Frequent (every 2 hours) blood sampling to assess midcycle hormonal dynamics in the monkey with the luteinized unruptured follicle and in five monkeys with an ov...

    journal_title：American journal of obstetrics and gynecology

    pub_type： 杂志文章

    doi：10.1016/0002-9378(86)90469-2

    authors： Schenken RS,Werlin LB,Williams RF,Prihoda TJ,Hodgen GD

    更新日期：1986-04-01 00:00:00

  • Hypoxia regulates the expression of fatty acid-binding proteins in primary term human trophoblasts.

    abstract：OBJECTIVE:Fatty acids (FAs) are essential for fetal development. Cellular FA uptake is modulated by fatty acid-binding proteins (FABPs). We hypothesized that hypoxia regulates the expression of FABPs in human trophoblasts. STUDY DESIGN:Primary term human trophoblasts were cultured for 72 hours in either standard (O2 =...

    journal_title：American journal of obstetrics and gynecology

    pub_type： 杂志文章

    doi：10.1016/j.ajog.2007.03.066

    authors： Biron-Shental T,Schaiff WT,Ratajczak CK,Bildirici I,Nelson DM,Sadovsky Y

    更新日期：2007-11-01 00:00:00

  • Clinical significance of elevated mean arterial blood pressure in second trimester and threshold increase in systolic or diastolic blood pressure during third trimester.

    abstract：:The purpose of this investigation was to determine the diagnostic value of an average mean arterial blood pressure in the second trimester of greater than or equal to 90 mm Hg and a threshold increase in diastolic blood pressure of greater than or equal to 15 mm Hg or in systolic blood pressure of greater than or equa...

    journal_title：American journal of obstetrics and gynecology

    pub_type： 杂志文章

    doi：10.1016/0002-9378(89)90463-8

    authors： Villar MA,Sibai BM

    更新日期：1989-02-01 00:00:00

  • Ultrasonographic diagnosis of a large placental intervillous thrombosis associated with elevated maternal serum alpha-fetoprotein level.

    abstract：:A placental lesion associated with elevated maternal serum alpha-fetoprotein level and a positive Kleihauer-Betke test is reported. Serial ultrasonograms showed a progressive increase in the echogenicity of the lesion that corresponded to a large intervillous thrombosis after delivery. This case illustrates the import...

    journal_title：American journal of obstetrics and gynecology

    pub_type： 杂志文章

    doi：10.1016/0002-9378(90)90626-i

    authors： Jauniaux E,Gibb D,Moscoso G,Campbell S

    更新日期：1990-11-01 00:00:00

  • Restoration of continence by pessaries: magnetic resonance imaging assessment of mechanism of action.

    abstract：OBJECTIVE:The objective of the study was to determine incontinence pessaries' mechanism of action by measuring changes on urodynamic studies (UDS) and dynamic magnetic resonance imaging (MRI) with and without pessaries in place. STUDY DESIGN:Women with stress incontinence had UDS and MRI performed with and without inc...

    journal_title：American journal of obstetrics and gynecology

    pub_type： 杂志文章

    doi：10.1016/j.ajog.2008.01.047

    authors： Komesu YM,Ketai LH,Rogers RG,Eberhardt SC,Pohl J

    更新日期：2008-05-01 00:00:00

  • Predictors of laparoscopic simulation performance among practicing obstetrician gynecologists.

    abstract：BACKGROUND:While simulation training has been established as an effective method for improving laparoscopic surgical performance in surgical residents, few studies have focused on its use for attending surgeons, particularly in obstetrics and gynecology. Surgical simulation may have a role in improving and maintaining ...

    journal_title：American journal of obstetrics and gynecology

    pub_type： 杂志文章

    doi：10.1016/j.ajog.2017.07.002

    authors： Mathews S,Brodman M,D'Angelo D,Chudnoff S,McGovern P,Kolev T,Bensinger G,Mudiraj S,Nemes A,Feldman D,Kischak P,Ascher-Walsh C

    更新日期：2017-11-01 00:00:00

  • Characterization of the transcriptome of chorioamniotic membranes at the site of rupture in spontaneous labor at term.

    abstract：OBJECTIVE:The purpose of this study was to compare the transcriptome between the site of membrane rupture and the chorioamniotic membranes away from the site of rupture. STUDY DESIGN:The transcriptome of amnion and chorion (n=20 each) from and distal to the site of rupture from women with spontaneous labor and vaginal...

    journal_title：American journal of obstetrics and gynecology

    pub_type： 杂志文章

    doi：10.1016/j.ajog.2010.02.045

    authors： Nhan-Chang CL,Romero R,Tarca AL,Mittal P,Kusanovic JP,Erez O,Mazaki-Tovi S,Chaiworapongsa T,Hotra J,Than NG,Kim JS,Hassan SS,Kim CJ

    更新日期：2010-05-01 00:00:00

  • Regulation of interleukin 8 production in the term human placenta during labor and by antigestagens.

    abstract：OBJECTIVE:Our purpose was to assess the effects of labor and antigestagens on production of interleukin 8 by the term human placenta and to localize interleukin 8 in first- and third- trimester placentas. STUDY DESIGN:The study was conducted by the Department of Obstetrics and Gynaecology of the University of Edinburg...

    journal_title：American journal of obstetrics and gynecology

    pub_type： 杂志文章

    doi：10.1016/s0002-9378(98)70275-3

    authors： Elliott CL,Kelly RW,Critchley HO,Riley SC,Calder AA

    更新日期：1998-07-01 00:00:00

  • Postoperative urinary incontinence after total abdominal hysterectomy or supracervical hysterectomy: a metaanalysis.

    abstract：OBJECTIVE:A metaanalysis of randomized trials was conducted to evaluate if the type of hysterectomy, total abdominal hysterectomy or supracervical hysterectomy, has an impact on the development of urinary incontinence. STUDY DESIGN:We searched MEDLINE, EMBASE, CINAHL, Biological Abstract, and the Cochrane Library up t...

    journal_title：American journal of obstetrics and gynecology

    pub_type： 杂志文章,meta分析

    doi：10.1016/j.ajog.2007.09.033

    authors： Robert M,Soraisham A,Sauve R

    更新日期：2008-03-01 00:00:00

  • A randomized trial that compared oral cefixime and intramuscular ceftriaxone for the treatment of gonorrhea in pregnancy.

    abstract：OBJECTIVE:The purpose of this study was to evaluate prospectively the Centers for Disease Control recommendations for the treatment of gonococcal infection in pregnancy. STUDY DESIGN:One hundred sixty-one women who were referred with probable endocervical gonorrhea underwent pretreatment endocervical, anal, and oral c...

    journal_title：American journal of obstetrics and gynecology

    pub_type： 临床试验,杂志文章,随机对照试验

    doi：10.1067/mob.2001.117662

    authors： Ramus RM,Sheffield JS,Mayfield JA,Wendel GD Jr

    更新日期：2001-09-01 00:00:00

  • Discussion: 'the interleukin-10 gene and cervical insufficiency' by Warren et al.

    abstract：:In the roundtable that follows, clinicians discuss a study published in this issue of the Journal in light of its methodology, relevance to practice, and implications for future research. Article discussed: Warren JE, Nelson LM, Stoddard GJ, et al. Polymorphisms in the promoter region of the interleukin-10 (IL-10) gen...

    journal_title：American journal of obstetrics and gynecology

    pub_type： 评论,杂志文章

    doi：10.1016/j.ajog.2009.07.019

    authors： Baxter JK,Berghella V,Rafael T,Baylson A,Moroz L

    更新日期：2009-10-01 00:00:00

  • Associations of gestational cardiovascular health with pregnancy outcomes: the Hyperglycemia and Adverse Pregnancy Outcome study.

    abstract：BACKGROUND:The American Heart Association's formal characterization of cardiovascular health combines several metrics in a health-oriented, rather than disease-oriented, framework. Although cardiovascular health assessment during pregnancy has been recommended, its significance for pregnancy outcomes is unknown. OBJEC...

    journal_title：American journal of obstetrics and gynecology

    pub_type： 杂志文章

    doi：10.1016/j.ajog.2020.07.053

    authors： Perak AM,Lancki N,Kuang A,Labarthe DR,Allen NB,Shah SH,Lowe LP,Grobman WA,Scholtens DM,Lloyd-Jones DM,Lowe WL Jr,Hyperglycemia and Adverse Pregnancy Outcome (HAPO) Study Cooperative Research Group.

    更新日期：2020-08-05 00:00:00

  • Acute gastric ulcer perforation in a 35 weeks' nulliparous patient with gastric banding.

    abstract：:We present a case of a primiparous patient at 35 weeks' gestation who had had laparoscopic gastric banding, and who presented to labor and delivery with protracted vomiting followed by an acute abdomen and fetal distress. An emergency surgery revealed acute gastric ulcer perforation. This complication, although rare, ...

    journal_title：American journal of obstetrics and gynecology

    pub_type： 杂志文章

    doi：10.1016/j.ajog.2004.03.036

    authors： Erez O,Maymon E,Mazor M

    更新日期：2004-11-01 00:00:00

  • Lupus anticoagulant and pregnancy.

    abstract：:A subset of women with a high rate of fetal wastage is identifiable among those with serologic but not necessarily clinical evidence of connective tissue disease. The presence of lupus anticoagulant in the plasma of a pregnant woman serves as a marker for a high rate of fetal wastage and risk of thrombosis. Lupus anti...

    journal_title：American journal of obstetrics and gynecology

    pub_type： 杂志文章,评审

    doi：10.1016/s0002-9378(85)80124-1

    authors： Lubbe WF,Liggins GC

    更新日期：1985-10-01 00:00:00

  • The effects of aminophylline and nifedipine on contractility of isolated pregnant human myometrium.

    abstract：:To characterize the effects of aminophylline and nifedipine on pregnant human myometrium, in vitro contractility studies were performed on myometrial strips obtained at cesarean section. The strips were stimulated with oxytocin (800 mU/L) to simulate labor and then were exposed to increasing concentrations of aminophy...

    journal_title：American journal of obstetrics and gynecology

    pub_type： 杂志文章

    doi：10.1016/s0002-9378(87)80373-3

    authors： Bird LM,Anderson NC Jr,Chandler ML,Young RC

    更新日期：1987-07-01 00:00:00

  • Fractional fetal thigh volume in the prediction of normal and abnormal fetal growth during the third trimester of pregnancy.

    abstract：BACKGROUND:Currently, 2-dimensional ultrasound estimation of fetal size rather than fetal growth is used to define fetal growth restriction, but single estimates in late pregnancy lack sensitivity and may identify small for gestational age rather than growth restriction. Single or longitudinal measures of 3-dimensional...

    journal_title：American journal of obstetrics and gynecology

    pub_type： 杂志文章

    doi：10.1016/j.ajog.2017.06.018

    authors： Simcox LE,Myers JE,Cole TJ,Johnstone ED

    更新日期：2017-10-01 00:00:00