HLA B-27 subtypes in Turkish patients with spondyloarthropathy and healthy controls.

abstract：:Twelve multiplex families with isolated congenital heart diseases (CHD) were included in the study. In 9 families the types of CHD in the living sibs were concordant and in the other 3 were discordant. All families were subjected to the following: (1) Pedigree construction, (2) clinical examination of the parents, aff...

journal_title：Disease markers

authors： Hafez M,Abdalla A,el-Shennawy F,Tawfik SH

更新日期：1986-12-01 00:00:00

abstract：INTRODUCTION:Vitamin D deficiency is associated with the onset and progression of hypertension and cardiovascular disease (CVD). However, mechanisms underlying vitamin D deficiency-mediated increased risk of CVD remain unknown. We sought to examine the differential effect of high-dose versus low-dose vitamin D suppleme...

journal_title：Disease markers

authors： Zaleski A,Panza G,Swales H,Arora P,Newton-Cheh C,Wang T,Thompson PD,Taylor B

更新日期：2015-01-01 00:00:00

abstract：:The terminal portion of the pol gene and the entire env gene of the human endogenous retrovirus ERV3 was screened for polymorphic nucleotides. For this purpose fragments amplified from the desired regions of ERV3 were subjected to single strand conformational analysis (SSCP analysis). Using this approach, we detected ...

journal_title：Disease markers

authors： Rasmussen HB,Clausen J

更新日期：1998-11-01 00:00:00

abstract：Background:Breast cancer is the commonest malignancy in women worldwide. It is estimated to affect approximately 1.5 million women annually and responsible for the greatest number of cancer-related mortalities among women. In 2018, breast cancer mortalities stood at 627,000 women representing approximately 15% of all c...

journal_title：Disease markers

authors： Arko-Boham B,Owusu BA,Aryee NA,Blay RM,Owusu EDA,Tagoe EA,Adams AR,Gyasi RK,Adu-Aryee NA,Mahmood S

更新日期：2020-05-24 00:00:00

abstract：:Cyclin Y (CCNY) is a novel cyclin and almost nothing is known about its role in human cancers. To investigate the clinical significance of serum anti-CCNY autoantibodies in nonsmall-cell lung carcinoma (NSCLC), the serum levels of CCNY protein in 264 patients with NSCLC, 103 patients with tuberculosis, and 89 healthy ...

journal_title：Disease markers

authors： Ma L,Yue W,Teng Y,Zhang L,Gu M,Wang Y

更新日期：2013-01-01 00:00:00

abstract：:Lung cancer remains a major cause of cancer-related lethality because of high incidence and recurrence in spite of significant advances in staging and therapies. Recent data indicates that stem cells situated throughout the airways may initiate cancer formation. These putative stem cells maintain protumorigenic charac...

journal_title：Disease markers

authors： Pine SR,Marshall B,Varticovski L

更新日期：2008-01-01 00:00:00

abstract：BACKGROUND:Previous studies on the role of inflammation in the pathophysiology of sickle cell disease (SCD) suggested that the CCR5Δ32 allele, which is responsible for the production of truncated C-C chemokine receptor type 5 (CCR5), could confer a selective advantage on patients with SCD because it leads to a less eff...

journal_title：Disease markers

authors： Lopes MP,Santos MN,Faber EW,Bezerra MA,Hatzlhofer BL,Albuquerque DM,Zaccariotto TR,Ribeiro DM,Araújo Ada S,Costa FF,Sonati Mde F

更新日期：2014-01-01 00:00:00

abstract：:Familial Amyloidotic Polyneuropathy (FAP) is a disorder characterized by the extracellular deposition of fibrillar Transthyretin (TTR) amyloid, with a special involvement of the peripheral nerve. Several extracellular matrix proteins have been found elevated in tissues from FAP patients, namely metalloproteinase-9 (MM...

journal_title：Disease markers

authors： Cardoso I,Brito M,Saraiva MJ

更新日期：2008-01-01 00:00:00

abstract：OBJECTIVE:Particularly interesting new cysteine-histidine rich protein (PINCH) is an important component of the local adhesion complexes and upregulated in several types of malignancies, and involved in the incidence and development of tumours. PINCH expression is also independently correlated with poorer survival in p...

journal_title：Disease markers

authors： Zhu ZL,Yan BY,Zhang Y,Yang YH,Wang ZM,Zhang HZ,Wang MW,Zhang XH,Sun XF

更新日期：2012-01-01 00:00:00

abstract：:S-100 protein was demonstrated in 28/31 melanoma tissue sections that had been previously stained by hematoxylin and eosin, including 17 from 19 primary melanomas and 11 from 12 metastases. Additional H & E stained sections from 11 metastatic and 13 primary melanomas were reacted with the monoclonal antibody NKI/C-3 a...

journal_title：Disease markers

authors： Paul E,Cochran AJ

更新日期：1988-10-01 00:00:00

abstract：AIM:To assess and compare the roles of plasma and urine concentrations of neutrophil gelatinase associated lipocalin (NGAL) and Cystatin C for early diagnosis of septic acute kidney injury (AKI) in adult critically ill patients. METHODS:Patients were divided into three groups as sepsis-non AKI, sepsis-AKI and non seps...

journal_title：Disease markers

authors： Aydoğdu M,Gürsel G,Sancak B,Yeni S,Sarı G,Taşyürek S,Türk M,Yüksel S,Senes M,Ozis TN

更新日期：2013-01-01 00:00:00

abstract：:Kidney insufficiency is a hallmark of nephropathia epidemica (NE). Little is known about the mechanisms of the NE kidney pathology, with current knowledge mainly based on findings in postmortem tissue. We have analyzed kidney damage biomarkers in urine collected from early- and late-phase NE using Bio-Plex kidney toxi...

journal_title：Disease markers

authors： Martynova EV,Maksudova AN,Shakirova VG,Abdulkhakov SR,Khaertynova IM,Anokhin VA,Ivanova VV,Abiola IM,Garanina EE,Tazetdinova LG,Valiullina AH,Khaiboullina SF

更新日期：2018-02-26 00:00:00

abstract：AIM:To determine the implication of the polymorphism, namely, A(TA)nTAA of UGT1A1 in lithogenesis for the first time in Tunisia among sickle cell anemia (SCA) children patients. MATERIAL AND METHODS:Our study was performed in 2010 and it involved 76 subjects chosen as control group characterized with normal hemoglobin...

journal_title：Disease markers

authors： Chaouch L,Talbi E,Moumni I,Ben Chaabene A,Kalai M,Chaouachi D,Mallouli F,Ghanem A,Abbes S

更新日期：2013-01-01 00:00:00

abstract：:Renal cell carcinoma (RCC) is one of the most common genitourinary cancers worldwide. Previous evidence shows that long noncoding RNA (LncRNA) APOC1P1 plays an important role in cancer development. However, the role of LncRNA APOC1P1 in ccRCC remains to be explored. LncRNA APOC1P1 expression in 283 ccRCC tissues and 3...

journal_title：Disease markers

authors： Sun C,Zhou Z,Shi H,Li F,Zhang G

更新日期：2019-12-01 00:00:00

abstract：:The total plasma concentration of homocysteine is a marker of this amino acid's atherogenic potential. However, the homocysteine pool exists almost entirely as oxidized homocysteine equivalents (OHcyE), composed of homocystine and cysteine-homocysteine disulphides (20-30%), and protein-bound disulphide (70-80%). We ha...

journal_title：Disease markers

authors： Iuliano M,De Tommaso G,Ragone R

更新日期：2009-01-01 00:00:00

abstract：BACKGROUND:We investigated the relationship between NT-pro-BNP, glomerular filtration rate (GFR), and all-cause mortality rates in a cohort of older people discharged from an internal medicine unit after admission for dyspnoea. PATIENTS AND METHODS:NT-pro-BNP was evaluated in serum samples of 134 patients aged 80 ± 6 ...

journal_title：Disease markers

authors： Fabbian F,De Giorgi A,Pala M,Volpato S,Portaluppi F,Zuliani G,Manfredini R

更新日期：2013-01-01 00:00:00

abstract：AIM:This study was conducted to find out the optimal vitamin D cutoff point in predicting activity of RA disease. MATERIALS AND METHODS:One hundred and two rheumatoid arthritis Saudi patients of both genders were recruited in this study. Vitamin D as 25-hydroxy-vitamin D [25(OH)D] was measured and serum level less tha...

journal_title：Disease markers

authors： Azzeh FS,Kensara OA

更新日期：2015-01-01 00:00:00

abstract：PURPOSE:The clinical behavior of unicystic ameloblastoma varies according to its subtype. The assessment of its proliferative capacity, neovascularization, and invasiveness using relevant immunomarkers may aid in appropriate surgical therapeutic protocol. METHODS:18 cases of clinically and histologically confirmed uni...

journal_title：Disease markers

authors： Sah P,Menon A,Kamath A,Chandrashekar C,Carnelio S,Radhakrishnan R

更新日期：2013-01-01 00:00:00

abstract：:Introduction. Chronic Periodontitis (CP) is suggested to be related to gene variations. Present study aims to quantitatively estimate the association between interleukin-6- (IL-6-) 174G/C polymorphism and CP susceptibility. Materials and Methods. Pubmed, Embase, and Web of Science were searched up to May 2016. The met...

journal_title：Disease markers

authors： Zhu J,Guo B,Fu M,Guo W,Yuan Y,Yuan H,Zhang S,Yu H

更新日期：2016-01-01 00:00:00

abstract：:Studies have shown that the maternal risk for Down syndrome (DS) may be modulated by alterations in folate metabolism. The aim of this study was to evaluate the influence of 12 genetic polymorphisms involved in folate metabolism on maternal risk for DS. In addition, we evaluated the impact of these polymorphisms on se...

journal_title：Disease markers

authors： Zampieri BL,Biselli JM,Goloni-Bertollo EM,Vannucchi H,Carvalho VM,Cordeiro JA,Pavarino EC

更新日期：2012-01-01 00:00:00

abstract：:The aim of this study was to assess the expression of MMP-9 and TIMP-1 in cancerous tissue as well as in the serum and plasma concentrations of these proteins in patients with laryngeal cancer and compare the results to the inflammatory reaction in healthy subjects. Twenty-seven patients who were diagnosed with laryng...

journal_title：Disease markers

authors： Matulka M,Konopka A,Mroczko B,Pryczynicz A,Kemona A,Groblewska M,Sieskiewicz A,Olszewska E

更新日期：2019-04-18 00:00:00

abstract：:Tumor-induced osteomalacia (TIO) is a rare acquired paraneoplastic disorder and fibroblast growth factor 23 (FGF23) plays a key role in its pathogenesis. This study was conducted to describe a novel FGF23 detecting procedure and describe clinical features of the disease. Fourteen TIO cases were retrieved and FGF23 exp...

journal_title：Disease markers

authors： Hu F,Jiang C,Zhang Q,Shi H,Wei L,Wang Y

更新日期：2016-01-01 00:00:00

abstract：:Prosthetic joint infection (PJI) is the most common cause of failure of total joint arthroplasty, but a gold standard for PJI diagnosis is still lacking. Advanced glycation end products (AGEs) are proinflammatory molecules inducing intracellular oxidative stress (OS) after binding to their cell membrane receptors (RAG...

journal_title：Disease markers

authors： Massaccesi L,Bonomelli B,Marazzi MG,Drago L,Romanelli MMC,Erba D,Papini N,Barassi A,Goi G,Galliera E

更新日期：2017-01-01 00:00:00

abstract：Objective:In order to further study the changes of cerebral functional connectivity in patients with toothache (TA), this study used the resting-state functional magnetic resonance imaging (rs-fMRI) technique and degree centrality (DC) analysis method. Methods:Eighteen TA patients (8 males, 10 females) and 18 healthy ...

journal_title：Disease markers

authors： Wu SN,Zhang MY,Shu HY,Liang RB,Ge QM,Pan YC,Zhang LJ,Li QY,Shao Y

更新日期：2020-12-28 00:00:00

abstract：BACKGROUND:Tumor cells show alterations in their glycosylation patterns when compared to normal cells. Lectins can be used to evaluate these glycocode changes. Chemiluminescence assay is an effective technique for quantitative analysis of proteins, nucleic acids, and carbohydrates due to its high sensitivity, specifici...

journal_title：Disease markers

authors： Lima LR,Bezerra MF,Almeida SM,Silva LP,Beltrão EI,Carvalho Júnior LB

更新日期：2013-01-01 00:00:00

abstract：:Hepatitis C virus (HCV) infection prevalence was determined in 34 hepatocellular carcinoma (HCC) patients with underlying liver cirrhosis. Serum alfa-fetoprotein level was found to be more than 1000 ng/ml (3153 +/- 1451) in those patients. Anti-HCV antibodies were detected in 84% of patients sera negative for hepatiti...

journal_title：Disease markers

authors： Mabrouk GM

更新日期：1997-11-01 00:00:00

abstract：:Our previous studies using the mass spectrum analysis provided evidence that fibrinopeptide A (FPA) could be a potential biomarker for schizophrenia diagnosis. We sought further to demonstrate that variants in the fibrinogen alpha chain gene (FGA) coded FPA might confer vulnerability to schizophrenia. 1,145 patients w...

journal_title：Disease markers

authors： Rao W,Zhou N,Zhang H,Liu R,Zhang S,Su Y,Yang G,Ma Y,Shi J,Yu Y,Yu Q

更新日期：2017-01-01 00:00:00

abstract：:A multitude of host genetic factors plays a crucial role in susceptibility to HIV-1 infection and progression to AIDS, which is highly variable among individuals and populations. This review focuses on the chemokine-receptor and chemokine genes, which were extensively studied because of their role as HIV co-receptor o...

journal_title：Disease markers

authors： Chatterjee A,Rathore A,Vidyant S,Kakkar K,Dhole TN

更新日期：2012-01-01 00:00:00

abstract：:Nonenzymatic glycosylation or glycation of macromolecules, especially proteins leading to their oxidation, play an important role in diseases. Glycation of proteins primarily results in the formation of an early stage and stable Amadori-lysine product which undergo further irreversible chemical reactions to form advan...

journal_title：Disease markers

authors： Ansari NA,Moinuddin,Ali R

更新日期：2011-01-01 00:00:00

abstract：:In recent researches, high expression of nesfatin-1/nucleobindin-2 (NUCB2) is linked to poor prognosis in prostate and colon cancer due to the enhancement in proliferation, migration, and invasion. However, the role of nesfatin-1 in bladder cancer is not clear. In this study, we examined the expression of NUCB2 in bla...

journal_title：Disease markers

authors： Liu GM,Xu ZQ,Ma HS

更新日期：2018-09-19 00:00:00