Abstract:
:Both novel enantiopure trans-1-aminobenz[f]indan-2-ols (4) were obtained from the racemate by the diastereomeric salt formation with (+)- and (-)-dibenzoyltartaric acids (8), respectively, and the absolute configuration of the enantiomer 4 in the less-soluble diastereomeric salt of racemic 4 with (+)-8 was determined to be (1S,2S) by an X-ray crystallographic analysis. The chiral recognition ability of the enantiopure amino alcohol was examined for the enantioseparation of racemic 2-arylalkanoic acids by the diastereomeric salt formation. The role of the naphthylene group of the amino alcohol was found to be closely associated with the stabilization of the crystal by CH/pi interactions on the basis of an X-ray crystallographic study.
journal_name
Chiralityjournal_title
Chiralityauthors
Kobayashi Y,Kinbara K,Sato M,Saigo Kdoi
10.1002/chir.20101subject
Has Abstractpub_date
2005-02-01 00:00:00pages
108-12issue
2eissn
0899-0042issn
1520-636Xjournal_volume
17pub_type
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