Abstract:
PURPOSE:To describe a case of a 46-year-old woman with an asymptomatic history of unilateral multiple serous detachments of the retinal pigment epithelium (PED) in the right eye, treated with photodynamic therapy (PDT) with verteporfin for recent onset of subfoveal choroidal neovascularization (CNV) with chorioretinal anastomoses (CRA). METHODS:Case report. RESULTS:Fluorescein and indocyanine green (ICG) angiography, performed with a Heidelberg scanning laser ophthalmoscope (SLO), demonstrated a predominantly classic foveal choroidal neovascular membrane associated with a PED and 1 one retinal and 2 two venous chorioretinal anastomoses. The left fundus was normal. PDT therapy was performed according to standard techniques. Three PDT treatments were performed at an interval of 3 months. Three months after the second PDT, visual acuity dropped to 20/200, with an enlargement of the neovascular network. One month after the third treatment, visual acuity deteriorated further and the CRA appeared enlarged, associated with a dense fibrotic reaction in the centere of the lesion. CONCLUSIONS:This clinical observation demonstrates that idiopathic serous detachments of the retinal pigment epithelium may represent predisposing changes to CNV development, and in the case CNV is associated with CRA, PDT may be unsuccessful.
journal_name
Eur J Ophthalmoljournal_title
European journal of ophthalmologyauthors
Fossarello M,Peiretti E,Zucca I,Serra Asubject
Has Abstractpub_date
2004-11-01 00:00:00pages
568-71issue
6eissn
1120-6721issn
1724-6016journal_volume
14pub_type
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journal_title:European journal of ophthalmology
pub_type: 杂志文章
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pub_type: 临床试验,杂志文章,多中心研究,随机对照试验
doi:
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