Abstract:
:Five new compounds, hibicuslide A (1), hibicuslide B (2), hibicuslide C (3), hibicutaiwanin (4), hibicusin (5), and fifty-one known compounds have been isolated from the stems of Hibiscus taiwanensis. The structures of these compounds were determined by spectroscopic and chemical transformation methods. Among them, mansonone H (19) and uncarinic acid A (30) inhibited HIV replication in H9 lymphocyte cells. The 9,9'-O-feruloyl-(-)-secoisolaricinresinol (12), myriceric acid C (29), and uncarinic acid A (30) showed cytotoxic activity against human lung carcinoma and breast carcinoma.
journal_name
Chem Pharm Bull (Tokyo)journal_title
Chemical & pharmaceutical bulletinauthors
Wu PL,Wu TS,He CX,Su CH,Lee KHdoi
10.1248/cpb.53.56subject
Has Abstractpub_date
2005-01-01 00:00:00pages
56-9issue
1eissn
0009-2363issn
1347-5223pii
JST.JSTAGE/cpb/53.56journal_volume
53pub_type
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