Abstract:
:Bone is a specialised connective tissue that, together with cartilage, makes up the skeleton. These tissues serve three functions: (a) mechanical support and site of muscle attachment for locomotion; (b) protection for vital organs and bone marrow and (c) a metabolic reserve of ions for the entire organism, especially calcium and phosphate. The fundamental constituents are the cells and a calcified extracellular matrix. The latter is particularly abundant and is composed of collagen fibres and a ground substance rich in glycosaminoglycans. The osteoclasts and osteoblasts have evolved to regulate the growth and turnover of bone and mediate ion fluxes between the bone and blood. The osteoclasts solubilise the mineralised organic matrix, and the osteoblasts are capable of forming bone and synthesising the various structural proteins and growth factors. Except during growth, a balance between bone resorption and formation is maintained. The activities of the bone formation and resorbing cells are regulated by local and systemic humoral factors, such as parathyroid hormone, cytokines, 1,25,dihydroxy vitamin D3 and the eicosanoids. Any dysfunction of either the local or systemic regulatory systems will lead to pathological changes in the rate of bone formation or resorption and ultimately a clinical disease of the skeleton.
journal_name
Br Dent Jjournal_title
British dental journalauthors
Meghji Sdoi
10.1038/sj.bdj.4807835subject
Has Abstractpub_date
1992-03-21 00:00:00pages
235-42issue
6eissn
0007-0610issn
1476-5373journal_volume
172pub_type
杂志文章,评审abstract::Continuing professional development should embrace all aspects of our professional life. Changes in the pattern of oral disease, developing concepts of specialisation and delivery of dental care require a flexible approach to the interface between the end of the undergraduate dental course and the early years of gener...
journal_title:British dental journal
pub_type: 杂志文章
doi:10.1038/sj.bdj.4809004
更新日期:1996-02-24 00:00:00
abstract::Introduction Despite excellent reviews in the past several years, the use of antibiotics as prophylaxis for implant placement remains controversial.Aim To assess the literature on the efficacy of prophylactic antibiotics prescribed prior to and immediately following implant surgery (PIFS).Outcomes Whether administrati...
journal_title:British dental journal
pub_type: 杂志文章
doi:10.1038/s41415-020-1649-9
更新日期:2020-06-01 00:00:00
abstract::This study describes a pilot project in which peer assisted learning (PAL) is used to teach dental clinical skills. A cluster randomised controlled trial compared opinions of Bachelor of Dental Surgery (BDS) students from peer-led groups versus staff-led groups in a clinical (impression taking) and a pre-clinical (han...
journal_title:British dental journal
pub_type: 杂志文章,随机对照试验
doi:10.1038/sj.bdj.2015.722
更新日期:2015-09-25 00:00:00
abstract::The value of glove wearing as part of dental surgery cross-infection control regimen is negated if gloves are punctured during use. An assessment of the procedures most likely to give rise to glove puncture is therefore of importance. Accordingly, 892 gloves worn by two dentists in general practice were examined for p...
journal_title:British dental journal
pub_type: 杂志文章
doi:10.1038/sj.bdj.4808187
更新日期:1993-06-05 00:00:00
abstract::The late Professor Aubrey Sheiham shaped dental public health as a discipline. He leaves behind cohorts of confident public health professionals in dentistry worldwide, including many former students, each with their own kaleidoscope of memories of him as teacher, mentor, colleague and friend. A paper that he publishe...
journal_title:British dental journal
pub_type: 传,历史文章,杂志文章
doi:10.1038/sj.bdj.2016.442
更新日期:2016-06-24 00:00:00
abstract:OBJECTIVES:To determine whether practising dental therapists, including dually qualified hygienist/therapists, considered themselves to be part of the clinical team and whether clinical work referred to them met with their expectations. METHODS:A postal survey enquired about work experiences of UK dental therapists, a...
journal_title:British dental journal
pub_type: 杂志文章
doi:10.1038/sj.bdj.2009.1104
更新日期:2009-12-12 00:00:00
abstract::This article presents a distant complication in the auricle following the administration of a standard inferior alveolar nerve block. The patient experienced profound numbness of the auricle on the ipsilateral side of the injection that lasted for about an hour following unintended injection to the auriculotemporal ne...
journal_title:British dental journal
pub_type: 杂志文章
doi:10.1038/sj.bdj.2009.559
更新日期:2009-07-11 00:00:00
abstract:OBJECTIVE:To evaluate shortened courses of antibiotics in the management of dentoalveolar abscesses. DESIGN:Prospective clinical study over a 3-year period. SETTING:Examinations department of the Liverpool University Dental Hospital. SUBJECTS:759 patients, with acute dentoalveolar abscesses associated with swelling,...
journal_title:British dental journal
pub_type: 杂志文章
doi:10.1038/sj.bdj.4809444
更新日期:1997-08-23 00:00:00
abstract::Background There is an urgent need to consider the skill-mix of the dental team to meet the oral health needs and demands of the population in general, and older people in particular. As people live longer and retain their teeth there will be a progressive change in both the volume and type of dental care required, an...
journal_title:British dental journal
pub_type: 杂志文章
doi:10.1038/sj.bdj.2010.132
更新日期:2010-02-13 00:00:00
abstract::Five hundred dental panoramic tomograms of patients over the age of 17 years were examined and any radiographic relationship of the mandibular second molar to the inferior dental canal noted. The position of the inferior dental canal within the mandible was also noted and compared with previous studies. In the populat...
journal_title:British dental journal
pub_type: 杂志文章
doi:10.1038/sj.bdj.4806893
更新日期:1989-07-08 00:00:00
abstract::In the aftermath of the devastating tsunami that hit South East Asia last December, a huge operation to try to identify thousands of victims got underway, with the help of many overseas medical and dental professionals. British dentist Gareth Pearson went to Thailand to try and help in this task and here recounts his ...
journal_title:British dental journal
pub_type: 杂志文章
doi:10.1038/sj.bdj.4812255
更新日期:2005-04-23 00:00:00
abstract::In the last few decades, the number of targeted chemotherapies approved for cancer treatment and undergoing clinical trials has risen. In comparison to conventional chemotherapy, targeted therapies (TTs) act on specific molecular targets involved in cancer development and progression, with reduced detrimental effects ...
journal_title:British dental journal
pub_type: 杂志文章
doi:10.1038/s41415-020-1365-5
更新日期:2020-03-01 00:00:00
abstract:AIM:To ascertain general dental practitioners' views on the use of stainless steel (pre-formed metal) crowns to restore carious primary molars. METHOD:Ninety-three general dental practitioners were selected at random from those practising in Lancashire, Cheshire and Greater Manchester in 2003 and interviewed separatel...
journal_title:British dental journal
pub_type: 杂志文章
doi:10.1038/sj.bdj.4812746
更新日期:2005-10-08 00:00:00
abstract::The current upward trend in the incidence of tuberculosis, particularly in the USA, and the problems of treating multiply drug resistant strains of Mycobacterium tuberculosis have caused a resurgence of interest in this infection. This review describes the microbiology, routes of transmission and epidemiology of Mycob...
journal_title:British dental journal
pub_type: 杂志文章,评审
doi:10.1038/sj.bdj.4809093
更新日期:1996-05-25 00:00:00
abstract::If you have a great idea for an innovative project or scheme that has an impact on patient care, or even if you've already completed one, then the inaugural Dental and Oral Health Innovation Awards could be your big opportunity to take it further. In this article, Danny Pine calls for entries to the Awards and looks a...
journal_title:British dental journal
pub_type: 杂志文章
doi:10.1038/sj.bdj.2008.413
更新日期:2008-05-24 00:00:00
abstract::Partly as a consequence of the inquiries into the events at the Bristol Royal Infirmary and the Royal Liverpool Children's Hospital (Alder Hey), the Government recently enacted the Human Tissue Act 2004. The main provisions of the Act came into force on 1 September 2006 and have potential implications for dentists. ...
journal_title:British dental journal
pub_type: 杂志文章
doi:10.1038/sj.bdj.4814378
更新日期:2006-12-23 00:00:00
abstract::This paper describes the psychiatric disorders seen in 138 consecutive attenders at a psychiatric clinic in a dental hospital. The disorders were rated using a standardised interview, and assigned a diagnosis in accordance with a multiaxial classification known as the DSM-III. The rate of psychiatric disorder seen in ...
journal_title:British dental journal
pub_type: 杂志文章
doi:10.1038/sj.bdj.4806683
更新日期:1989-01-07 00:00:00
abstract:AIM:The primary aim was to evaluate the effect of ethnicity, social deprivation and oral health on oral self perceptions of 14-15-year-old Asians and Whites. A secondary aim was to assess the influence of ethnicity and social deprivation on oral treatment need in the same sample. DESIGN:A cross-sectional epidemiologic...
journal_title:British dental journal
pub_type: 杂志文章
doi:10.1038/sj.bdj.4809813
更新日期:1998-10-10 00:00:00
abstract::Aim To investigate the relationship between deprivation and distance to NHS dental providers in Scotland, Wales and Northern Ireland.Methods A total of 1,795 NHS dental practices were located at the smallest geographic areas for Scotland, Wales and Northern Ireland. A geographic information system (GIS) was used to ov...
journal_title:British dental journal
pub_type: 杂志文章
doi:10.1038/s41415-020-1748-7
更新日期:2020-07-01 00:00:00
abstract::Bony disease is typically evident with radiographic examination. Loss of bone mass consistent with osteoporosis is evident on plain dental radiographs, and it is reasonable to expect that anti-resorptive treatment of osteoporosis would lead to changes in radiodensity of structures visible on dental radiographs. Review...
journal_title:British dental journal
pub_type: 杂志文章
doi:10.1038/sj.bdj.2017.307
更新日期:2017-04-07 00:00:00
abstract::Angiotensin converting enzyme (ACE) inhibitors are a commonly prescribed, effective medication in the treatment of hypertension and heart failure. Several side-effects of dental relevance can occur including angioedema of the lips, mouth and throat. This adverse effect is well reported and can be fatal, but it is not ...
journal_title:British dental journal
pub_type: 杂志文章
doi:10.1038/sj.bdj.2008.982
更新日期:2008-11-22 00:00:00
abstract::A case is reported where the callus in a mandibular osteotomy site underwent distraction by means of an intra-oral device. The procedure was undertaken in a 9-year-old patient diagnosed with hemifacial microsomia type I. Using rapid prototyping from a radiographic scan of the facial skeleton an acrylic model was made ...
journal_title:British dental journal
pub_type: 杂志文章
doi:
更新日期:1997-07-26 00:00:00
abstract::It is now more than one year since the Specialist List in Orthodontics closed on 30 June 2000. I therefore felt it appropriate that I should give my views on the list, having probably had more experience in this process than any other dentist in the UK. ...
journal_title:British dental journal
pub_type: 社论
doi:10.1038/sj.bdj.4801168a
更新日期:2001-09-22 00:00:00
abstract::There are many varying factors which impact on the behaviour of reluctant patients and the understanding of theoretical behavioural models can help to understand some of the key issues. This paper considers such models and the effective use of marketing communications in helping to change behaviour. The paper conclude...
journal_title:British dental journal
pub_type: 杂志文章
doi:10.1038/sj.bdj.4800135
更新日期:1999-05-08 00:00:00
abstract::We report a case of Wegener's granulomatosis (WG), localised to the upper aerodigestive tract, which presented as an unusual form of hyperplastic gingivitis in a 36-year-old female. The clinical, serological and histopathological findings are described. The resemblance of the affected gums to over-ripe strawberries is...
journal_title:British dental journal
pub_type: 杂志文章
doi:10.1038/sj.bdj.4808316
更新日期:1993-11-06 00:00:00
abstract:OBJECTIVE:To review episodes of infective endocarditis involving dental procedures that have resulted in litigation and to determine if any clinical recommendations can be obtained. DESIGN:13-year retrospective study. INTERVENTION:Patient records were analysed to identify the probable cause of infective endocarditis....
journal_title:British dental journal
pub_type: 杂志文章
doi:10.1038/sj.bdj.4809414
更新日期:1997-06-28 00:00:00
abstract::Routines for disinfecting working surfaces in dental surgeries are difficult to monitor without time-consuming and labour-intensive microbiological techniques, yet effective monitoring is a vital part of cross-infection control. Easy to use, on-site methods would be valuable in this context. This study evaluates a por...
journal_title:British dental journal
pub_type: 杂志文章
doi:10.1038/sj.bdj.4807546
更新日期:1991-05-11 00:00:00
abstract::A novel calcium-based cement was launched in 2009 claiming to be a revolutionary material capable of offering a bioactive and biocompatible replacement for dentine. The calcium-based cement has been reported to encourage the repair and regeneration of lost dental tissue, preserve pulp vitality, promote pulp healing an...
journal_title:British dental journal
pub_type: 杂志文章
doi:10.1038/sj.bdj.2013.53
更新日期:2013-01-01 00:00:00
abstract::Objective This paper presents the results of a systematic review, designed to explore how patient-centred care (PCC) is defined in the dental literature.Method An electronic search of MEDLINE (1946-2012), Embase (1980-2012) PsycINFO (1806-2012), the Cochrane Library and non-peer reviewed literature was conducted using...
journal_title:British dental journal
pub_type: 杂志文章
doi:10.1038/sj.bdj.2016.777
更新日期:2016-10-21 00:00:00
abstract:OBJECTIVE:To evaluate published reviews of the appropriateness of prophylactic removal of impacted third molars. DESIGN:Systematic review and critical appraisal of relevant reviews. METHODS:Computerised databases (Medline and Embase), the Index to Dental Literature, and the references of articles were searched to ide...
journal_title:British dental journal
pub_type: 杂志文章,评审
doi:10.1038/sj.bdj.4809378
更新日期:1997-05-10 00:00:00