Zygotic induction of plasmid ssb and psiB genes following conjugative transfer of Incl1 plasmid Collb-P9.

Abstract:

:The Incl1 conjugative plasmid Collb-P9 carries a psiB gene that prevents induction of the SOS response in host bacteria. This locus is located 2.5 kb downstream of the ssb (single-stranded DNA-binding protein) gene in the leading region. This portion of Collb is strikingly similar to part of the leading region of the otherwise distinct F plasmid. Expression of psiB and ssb is increased when the host cell is exposed to an SOS-inducing treatment or the Collb transfer system is derepressed. Moreover, expression of both genes on a derepressed plasmid is strongly enhanced in conjugatively infected recipient cells. Carriage of the psiB gene by Collb is shown to prevent a low level of SOS induction following conjugation. Plasmid ssb and psiB genes may function to promote installation of the replicon in the new cell.

journal_name

Mol Microbiol

journal_title

Molecular microbiology

authors

Jones AL,Barth PT,Wilkins BM

doi

10.1111/j.1365-2958.1992.tb01507.x

subject

Has Abstract

pub_date

1992-03-01 00:00:00

pages

605-13

issue

5

eissn

0950-382X

issn

1365-2958

journal_volume

6

pub_type

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