Interrelations between brachial endothelial function and carotid intima-media thickness in young adults: the cardiovascular risk in young Finns study.

abstract：BACKGROUND:PCTP (phosphatidylcholine transfer protein) regulates the intermembrane transfer of phosphatidylcholine. Higher platelet PCTP expression is associated with increased platelet responses on activation of protease-activated receptor 4 thrombin receptors noted in black subjects compared with white subjects. Litt...

journal_title：Circulation

authors： Mao G,Songdej N,Voora D,Goldfinger LE,Del Carpio-Cano FE,Myers RA,Rao AK

更新日期：2017-09-05 00:00:00

abstract：BACKGROUND:Basic fibroblast growth factor (bFGF) has been shown to reduce infarct size in canine acute myocardial infarction; however, the mechanism of tissue salvage remains uncertain. We evaluated the effect of bFGF on infarct size in a model of acute infarction in which coronary occlusion was followed by prolonged r...

journal_title：Circulation

authors： Horrigan MC,MacIsaac AI,Nicolini FA,Vince DG,Lee P,Ellis SG,Topol EJ

更新日期：1996-10-15 00:00:00

abstract：BACKGROUND:We previously demonstrated that ischemic postconditioning decreases creatine kinase release, a surrogate marker for infarct size, in patients with acute myocardial infarction. Our objective was to determine whether ischemic postconditioning could afford (1) a persistent infarct size limitation and (2) an imp...

journal_title：Circulation

authors： Thibault H,Piot C,Staat P,Bontemps L,Sportouch C,Rioufol G,Cung TT,Bonnefoy E,Angoulvant D,Aupetit JF,Finet G,André-Fouët X,Macia JC,Raczka F,Rossi R,Itti R,Kirkorian G,Derumeaux G,Ovize M

更新日期：2008-02-26 00:00:00

abstract：BACKGROUND:The first compounds considered for stent-based delivery, such as heparin, were chosen on the basis of promising tissue culture and animal experiments, and yet they have failed to stop restenosis clinically. More recent compounds, such as paclitaxel, are of a different sort, being hydrophobic in nature, and t...

journal_title：Circulation

authors： Hwang CW,Wu D,Edelman ER

更新日期：2001-07-31 00:00:00

abstract：:The term "linking" has been used specifically to describe the mechanism for perpetuation of functional anterograde bundle branch block: namely, repetitive transseptal retrograde concealed penetration by impulses propagating along the contralateral bundle. We present selected examples that demonstrate tht linking-type ...

journal_title：Circulation

authors： Lehmann MH,Denker S,Mahmud R,Addas A,Akhtar M

更新日期：1985-02-01 00:00:00

abstract：BACKGROUND:The coexistence of atrial fibrillation (AF) and atrial flutter (AFL) is well recognized. AF precedes the onset of AFL in almost all instances. We evaluated the effect of 2 ablation strategies in patients with paroxysmal AF (PAF) and AFL. METHODS AND RESULTS:Ninety-eight patients with PAF/AFL were prospectiv...

journal_title：Circulation

authors： Moreira W,Timmermans C,Wellens HJ,Mizusawa Y,Philippens S,Perez D,Rodriguez LM

更新日期：2007-12-11 00:00:00

abstract：:To examine the effects of propranolol and nifedipine on exercise-induced attack in patients with variant angina, exercise 201Tl myocardial scintigraphy with quantitative analysis by emission-computed tomography was performed in 20 patients with variant angina after oral propranolol (80 mg), nifedipine (20 mg), and pla...

journal_title：Circulation

authors： Kugiyama K,Yasue H,Horio Y,Morikami Y,Fujii H,Koga Y,Kojima A,Takahashi M

更新日期：1986-08-01 00:00:00

abstract：BACKGROUND:For a long time, enteroviruses have been considered to be the most common cause of acute viral myocarditis (MC), with possible transition from MC to dilated cardiomyopathy (DCM). Recent investigations have shown, however, that other viruses are also frequently encountered in MC patients, suggesting that pers...

journal_title：Circulation

authors： Kühl U,Pauschinger M,Noutsias M,Seeberg B,Bock T,Lassner D,Poller W,Kandolf R,Schultheiss HP

更新日期：2005-02-22 00:00:00

abstract：BACKGROUND:Emerging studies suggest that early administration of dual antiplatelet therapy may be better than monotherapy for prevention of early recurrent stroke and cardiovascular outcomes in acute ischemic stroke and transient ischemic attack (TIA). We performed a meta-analysis of randomized, controlled trials evalu...

journal_title：Circulation

authors： Wong KS,Wang Y,Leng X,Mao C,Tang J,Bath PM,Markus HS,Gorelick PB,Liu L,Lin W,Wang Y

更新日期：2013-10-08 00:00:00

abstract：BACKGROUND:The use of molecular biological techniques has demonstrated the importance of enteroviral infection of the myocardium in the pathogenesis of myocarditis and dilated cardiomyopathy in adults and adenovirus and enterovirus infection in children. The aim of this study was to determine the frequency of adenovira...

journal_title：Circulation

authors： Pauschinger M,Bowles NE,Fuentes-Garcia FJ,Pham V,Kühl U,Schwimmbeck PL,Schultheiss HP,Towbin JA

更新日期：1999-03-16 00:00:00

abstract：BACKGROUND:Postmortem interrogations of cardiac implantable electronic devices (CIEDs), recommended at autopsy in suspected cases of sudden cardiac death, are rarely performed, and data on systematic postmortem CIED analysis in the forensic pathology are missing. The aim of the study was to determine whether nonselecti...

journal_title：Circulation

authors： Lacour P,Buschmann C,Storm C,Nee J,Parwani AS,Huemer M,Attanasio P,Boldt LH,Rauch G,Kucher A,Pieske B,Haverkamp W,Blaschke F

更新日期：2018-06-19 00:00:00

abstract：BACKGROUND:The extent of the peri-infarct zone by magnetic resonance imaging (MRI) has been related to all-cause mortality in patients with coronary artery disease. This relationship may result from arrhythmogenesis in the infarct border. However, the relationship between tissue heterogeneity in the infarct periphery a...

journal_title：Circulation

authors： Schmidt A,Azevedo CF,Cheng A,Gupta SN,Bluemke DA,Foo TK,Gerstenblith G,Weiss RG,Marbán E,Tomaselli GF,Lima JA,Wu KC

更新日期：2007-04-17 00:00:00

abstract：:In this study we extended the characterization of outcome in 1214 medically treated patients with coronary disease by considering nonfatal infarction and death together as ischemic events. At 7 years, the cumulative event rate was 47% (18% for nonfatal infarction as the initial event and 29% for death as the initial e...

journal_title：Circulation

authors： Harris PJ,Lee KL,Harrell FE Jr,Behar VS,Rosati RA

更新日期：1980-10-01 00:00:00

abstract：BACKGROUND:Percutaneous transluminal coronary angioplasty of the infarct-related artery in stable survivors of acute myocardial infarction is often performed, even in patients without any symptoms or residual ischemia. Despite the lack of randomized studies, it is widely believed that this intervention will improve the...

journal_title：Circulation

authors： Zeymer U,Uebis R,Vogt A,Glunz HG,Vöhringer HF,Harmjanz D,Neuhaus KL,ALKK-Study Group.

更新日期：2003-09-16 00:00:00

abstract：BACKGROUND:Age is a predictor of cognitive dysfunction after cardiac surgery, but the mechanism is unknown. The purpose of our study was to determine whether age-related decrements in cognition are associated with cerebral blood flow (CBF) autoregulation during cardiopulmonary bypass (CPB). METHODS AND RESULTS:Cogniti...

journal_title：Circulation

authors： Newman MF,Croughwell ND,Blumenthal JA,White WD,Lewis JB,Smith LR,Frasco P,Towner EA,Schell RM,Hurwitz BJ

更新日期：1994-11-01 00:00:00

abstract：BACKGROUND:Age is an important determinant of outcomes for patients with acute coronary syndromes (ACS); however, community practice reveals a disproportionately lower use of cardiovascular medications and invasive treatment even among elderly patients with ACS who would stand to benefit. Reasons include limited trial ...

journal_title：Circulation

authors： Alexander KP,Newby LK,Cannon CP,Armstrong PW,Gibler WB,Rich MW,Van de Werf F,White HD,Weaver WD,Naylor MD,Gore JM,Krumholz HM,Ohman EM,American Heart Association Council on Clinical Cardiology.,Society of Geriatric Cardiology

更新日期：2007-05-15 00:00:00

abstract：BACKGROUND:Spectral analysis of heart rate (HR) variability (HRV) requires, as a rule, some level of stationarity and, as a result, is inadequate to quantify biological transients. A time-/frequency-domain method (TF) was developed to obtain an instant spectral power (SP) of HRV during tilt. METHODS AND RESULTS:HR was...

journal_title：Circulation

authors： Jasson S,Médigue C,Maison-Blanche P,Montano N,Meyer L,Vermeiren C,Mansier P,Coumel P,Malliani A,Swynghedauw B

更新日期：1997-11-18 00:00:00

abstract：BACKGROUND:The use of bipolar endocardial electrogram characteristics to guide radiofrequency (RF) current catheter ablation of accessory pathways (APs) has been advocated by several investigators. However, the influences of a varying anatomy of the AP and the atrioventricular groove, of different ablative approaches, ...

journal_title：Circulation

authors： Cappato R,Schlüter M,Mont L,Kuck KH

更新日期：1994-08-01 00:00:00

abstract：BACKGROUND:The cross-talk between vascular endothelial growth factor (VEGF)-A, angiopoietin (Ang), and VE-cadherin coregulates endothelial cell (EC) survival. Cardiac expression of VEGF-A but not its receptor KDR is blunted in dilated cardiomyopathy (DCM). Whether VE-cadherin/Ang function is affected in DCM is unknown....

journal_title：Circulation

authors： Schäfer R,Abraham D,Paulus P,Blumer R,Grimm M,Wojta J,Aharinejad S

更新日期：2003-09-30 00:00:00

abstract：BACKGROUND:Thoracic endovascular aortic repair offers a less invasive approach for the treatment of ruptured descending thoracic aortic aneurysms (rDTAA). Due to the low incidence of this life-threatening condition, little is known about the outcomes of endovascular repair of rDTAA and the factors that affect these out...

journal_title：Circulation

authors： Jonker FH,Verhagen HJ,Lin PH,Heijmen RH,Trimarchi S,Lee WA,Moll FL,Athamneh H,Muhs BE

更新日期：2010-06-29 00:00:00

abstract：BACKGROUND:Ventricular tachyarrhythmias present a unique set of stimuli to arterial and cardiopulmonary baroreceptors by increasing cardiac filling pressures and decreasing arterial pressure. The net effect on the control of sympathetic nerve activity (SNA) in humans is unknown. The purpose of this study was to determi...

journal_title：Circulation

authors： Smith ML,Joglar JA,Wasmund SL,Carlson MD,Welch PJ,Hamdan MH,Quan K,Page RL

更新日期：1999-08-10 00:00:00

abstract：BACKGROUND:Left ventricular remodeling after myocardial infarction (MI) involves the hypertrophic growth of cardiomyocytes and the accumulation of fibrillar collagen in the interstitial space. We evaluated the role of kinins in postinfarction ventricular remodeling and their potential contribution to the antiremodeling...

journal_title：Circulation

authors： Wollert KC,Studer R,Doerfer K,Schieffer E,Holubarsch C,Just H,Drexler H

更新日期：1997-04-01 00:00:00

abstract：BACKGROUND:Hypertension is a major modifiable cardiovascular risk factor. The present longitudinal study aimed to examine the best combination of childhood physical and environmental factors to predict adult hypertension and furthermore whether newly identified genetic variants for blood pressure increase the predictio...

journal_title：Circulation

authors： Juhola J,Oikonen M,Magnussen CG,Mikkilä V,Siitonen N,Jokinen E,Laitinen T,Würtz P,Gidding SS,Taittonen L,Seppälä I,Jula A,Kähönen M,Hutri-Kähönen N,Lehtimäki T,Viikari JS,Juonala M,Raitakari OT

更新日期：2012-07-24 00:00:00

abstract：:The relationship between fasting plasma cholesterol and triglyceride concentrations and the frequency and extensiveness of coronary artery disease (CAD) was studied in 496 subjects evaluated for chest pain by coronary arteriography at The Methodist Hospital. One hundred six of the patients had no CAD while 390 had 25%...

journal_title：Circulation

authors： Gotto AM,Gorry GA,Thompson JR,Cole JS,Trost R,Yeshurun D,DeBakey ME

更新日期：1977-11-01 00:00:00

abstract：BACKGROUND:The mechanism and treatment of diastolic heart failure are poorly understood. We compared the effects of an ACE inhibitor, an angiotensin receptor blocker (ARB), and their combination on diastolic heart failure in Dahl salt-sensitive (DS) rats. METHODS AND RESULTS:DS rats fed an 8% NaCl diet from 7 weeks of...

journal_title：Circulation

authors： Kim S,Yoshiyama M,Izumi Y,Kawano H,Kimoto M,Zhan Y,Iwao H

更新日期：2001-01-02 00:00:00

abstract：BACKGROUND:Exaggerated pulmonary hypertension is thought to play an important part in the pathogenesis of high-altitude pulmonary edema (HAPE). Endothelin-1 is a potent pulmonary vasoconstrictor peptide that also augments microvascular permeability. METHODS AND RESULTS:We measured endothelin-1 plasma levels and pulmon...

journal_title：Circulation

authors： Sartori C,Vollenweider L,Löffler BM,Delabays A,Nicod P,Bärtsch P,Scherrer U

更新日期：1999-05-25 00:00:00

abstract：:Atherosclerotic coronary artery disease is the major cause of late cardiac transplant failure secondary to silent ischemia and infarction. To increase the longevity of cardiac homografts, we performed percutaneous transluminal coronary angioplasty (PTCA) in five male patients (aged 45 +/- 7 years, mean +/- SEM); 17 le...

journal_title：Circulation

authors： Vetrovec GW,Cowley MJ,Newton CM,Lewis SA,DiSciascio G,Thompson JA,Hastillo A,Lower R,Hess M

更新日期：1988-11-01 00:00:00

abstract：BACKGROUND:Cardiac arrest without evident cardiac disease may be caused by subclinical genetic conditions. Provocative testing to unmask a phenotype is often necessary to detect primary electrical disease, direct genetic testing, and perform family screening. METHODS AND RESULTS:Patients with apparently unexplained ca...

journal_title：Circulation

authors： Krahn AD,Healey JS,Chauhan V,Birnie DH,Simpson CS,Champagne J,Gardner M,Sanatani S,Exner DV,Klein GJ,Yee R,Skanes AC,Gula LJ,Gollob MH

更新日期：2009-07-28 00:00:00

abstract：BACKGROUND:Aortic counterpulsation has been observed to reduce the rate of reocclusion of the infarct-related artery after patency has been restored during acute myocardial infarction in observational studies. To evaluate the benefit-to-risk ratio of aortic counterpulsation during the early phase of myocardial infarcti...

journal_title：Circulation

authors： Ohman EM,George BS,White CJ,Kern MJ,Gurbel PA,Freedman RJ,Lundergan C,Hartmann JR,Talley JD,Frey MJ

更新日期：1994-08-01 00:00:00

abstract：BACKGROUND:Serum uric acid (UA) could be a valid prognostic marker and useful for metabolic, hemodynamic, and functional (MFH) staging in chronic heart failure (CHF). METHODS AND RESULTS:For the derivation study, 112 patients with CHF (age 59+/-12 years, peak oxygen consumption [Vo2] 17+/-7 mL/kg per minute) were recr...

journal_title：Circulation

authors： Anker SD,Doehner W,Rauchhaus M,Sharma R,Francis D,Knosalla C,Davos CH,Cicoira M,Shamim W,Kemp M,Segal R,Osterziel KJ,Leyva F,Hetzer R,Ponikowski P,Coats AJ

更新日期：2003-04-22 00:00:00