Preterm premature rupture of membranes: results of expectant management in patients with cervical cultures positive for group B streptococcus or Neisseria gonorrhoeae.

Abstract:

OBJECTIVE:The antepartum course and short-term neonatal outcome for patients with premature rupture of membranes between 26 and 33 weeks' gestation with positive cervical cultures for group B streptococcus or Neisseria gonorrhoeae were reviewed. STUDY DESIGN:A retrospective analysis of 182 patients managed expectantly over a 3-year period was done. Thirty-four patients had cervical cultures positive for group B streptococcus, 11 had positive cultures for Neisseria gonorrhoeae, and 137 had negative cultures. Prophylactic antibiotics were routinely given, and antibiotic therapy was continued in patients with positive cultures. RESULTS:There was no difference between groups in latent phase or maternal morbidity. The incidence of neonatal pneumonia was increased in those with positive cervical cultures (p = 0.009, odds ratio 6.9, 90% confidence interval 2.1 to 22.8), but there was no difference in neonatal sepsis, respiratory distress, or neonatal mortality. CONCLUSION:These data support the conservative or expectant management of premature rupture of membranes between 26 and 33 weeks in patients with positive cervical cultures who are given prophylactic antibiotic therapy.

journal_name

Am J Obstet Gynecol

authors

Maxwell GL,Watson WJ

doi

10.1016/0002-9378(92)91369-l

subject

Has Abstract

pub_date

1992-03-01 00:00:00

pages

945-9

issue

3

eissn

0002-9378

issn

1097-6868

pii

0002-9378(92)91369-L

journal_volume

166

pub_type

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