Making the diagnosis of coeliac disease: is there a role for push enteroscopy?

Abstract:

:Coeliac disease is one of the most common genetically based diseases. The wide clinical spectrum of the disease and the availability of highly specific antibody testing have led to an increased number of patients undergoing gastroscopy with distal duodenal biopsies. Histological confirmation of the characteristic small bowel changes with partial or total villous atrophy remain the gold standard for making a diagnosis. Patients with positive antibodies but initially negative or uncertain biopsies pose a particular diagnostic dilemma. Due to the patchiness of the histological changes, push enteroscopy with jejunal biopsies can play a valuable role in this group of patients. Similarly, patients with refractory coeliac disease can benefit from push enteroscopy with jejunal biopsies.

authors

Frenz MB,Mee AS

doi

10.1097/00042737-200411000-00007

subject

Has Abstract

pub_date

2004-11-01 00:00:00

pages

1127-9

issue

11

eissn

0954-691X

issn

1473-5687

pii

00042737-200411000-00007

journal_volume

16

pub_type

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