Abstract：
PURPOSE:To compare the effectiveness of brinzolamide 1% (Azopt) and brimonidine 0.2% (Alphagan) with a placebo in preventing an early increase in intraocular pressure (IOP) after phacoemulsification. SETTING:Department of Ophthalmology, Baskent University, School of Medicine, Ankara, Turkey. METHODS:In this prospective double-masked study, 90 eyes of 90 patients having clear corneal phacoemulsification were randomly divided into 3 groups of 30 eyes each. One hour before surgery, 1 group received 1 drop of brinzolamide 1%, another received 1 drop of brimonidine 0.2%, and the third received 1 drop of a balanced saline solution (placebo). The IOP was measured preoperatively and 3 and 16 to 20 hours postoperatively. RESULTS:Three hours postoperatively, the mean IOP increased by 4.2 mm Hg +/- 7.0 (SD), 3.2 +/- 6.4 mm Hg, and 5.3 +/- 4.2 mm Hg in the brinzolamide, brimonidine, and placebo groups, respectively. The IOP increase from baseline was significant in all 3 groups (all P<.01), with no difference between the groups (P>.05). The change in IOP at 16 to 20 hours was 0.2 +/- 2.8 mm Hg, 0.2 +/- 2.4 mm Hg, and -0.8 +/- 2.4 mm Hg, respectively. The changes were not significant compared to baseline (all P>.05). Six eyes (20%) in the brinzolamide group, 5 eyes (16.7%) in the brimonidine group, and 7 eyes (23.3%) in the placebo group had an IOP higher than 25 mm Hg 3 hours postoperatively; the difference between groups was not significant (P =.8). CONCLUSION:Prophylactic use of 1 drop of brinzolamide or brimonidine was not more effective than a placebo in controlling early postoperative IOP elevations after clear corneal phacoemulsification.
journal_name
J Cataract Refract Surgjournal_title
Journal of cataract and refractive surgeryauthors
Cetinkaya A,Akman A,Akova YAdoi
10.1016/j.jcrs.2003.12.050subject
Has Abstractpub_date
2004-08-01 00:00:00pages
1736-41issue
8eissn
0886-3350issn
1873-4502pii
S0886335004000744journal_volume
30pub_type
临床试验,杂志文章,随机对照试验abstract：PURPOSE:To evaluate the efficacy and safety of photorefractive keratectomy (PRK) with intraoperative application of mitomycin-C (MMC). SETTING:Yonsei Eye Center, Seoul, South Korea. METHODS:This retrospective noncomparative case series included 536 patients (1011 eyes) who had had PRK with intraoperative application ...
journal_title：Journal of cataract and refractive surgery
pub_type： 杂志文章
doi：10.1016/j.jcrs.2005.05.027
更新日期：2005-12-01 00:00:00
abstract：PURPOSE:To determine whether the keratometric and refractive surgical effects of paired intrastromal corneal ring segments (ICRS) depend on their alignment relative to steep and flat topographic meridians. SETTING:St. Paul's Eye Unit, Royal Liverpool University Hospital, Liverpool, United Kingdom. DESIGN:Comparative ...
journal_title：Journal of cataract and refractive surgery
pub_type： 杂志文章
doi：10.1016/j.jcrs.2012.04.024
更新日期：2012-08-01 00:00:00
abstract：:Since the inception of small-incision lenticule extraction (SMILE), many surgeons have speculated the lack of an adequate and standard retreatment procedure will impede its popularity. However, more than 1 million patients worldwide have had this surgery, with visual outcomes nearly equivalent to current laser in situ...
journal_title：Journal of cataract and refractive surgery
pub_type： 杂志文章,评审
doi：10.1016/j.jcrs.2018.07.047
更新日期：2018-11-01 00:00:00
abstract：:Measurement of laser in situ keratomileusis flap thickness is required to estimate residual bed thickness. Historically, flap thickness has been assumed, estimated based on microkeratome head labeling, guessed based on flap handling characteristics, or calculated by subtraction pachymetry. We describe a method for mea...
journal_title：Journal of cataract and refractive surgery
pub_type： 杂志文章
doi：10.1016/j.jcrs.2006.01.003
更新日期：2006-04-01 00:00:00
abstract：PURPOSE:To devise a comprehensive cataract surgery complexity score system for the selection of appropriate cases for trainees using evidence-based, validated risk factors for posterior capsule rupture, patient-specific factors, and complexity stratification recommendations to minimize complications, optimize outcomes,...
journal_title：Journal of cataract and refractive surgery
pub_type： 杂志文章
doi：10.1016/j.jcrs.2018.04.036
更新日期：2018-06-01 00:00:00
abstract：:We report a case of toxic anterior segment syndrome (TASS) that developed after cataract surgery. A 78-year-old woman had uneventful phacoemulsification via a clear corneal incision with implantation of an acrylic intraocular lens. One day postoperatively, diffuse corneal edema and anterior chamber inflammation were e...
journal_title：Journal of cataract and refractive surgery
pub_type： 杂志文章
doi：10.1016/j.jcrs.2009.07.052
更新日期：2010-02-01 00:00:00
abstract：:Posterior-assisted levitation is used to retrieve and levitate a sinking nucleus in cataract surgery associated with posterior capsule rupture. After the nucleus is levitated in the anterior chamber, the intraocular lens (IOL) scaffold procedure helps emulsify the nuclear remnants with the phacoemulsification probe an...
journal_title：Journal of cataract and refractive surgery
pub_type： 杂志文章
doi：10.1016/j.jcrs.2017.06.004
更新日期：2017-07-01 00:00:00
abstract：PURPOSE:To evaluate the influence of posterior corneal astigmatism on total corneal astigmatism in patients with 1.00 diopter (D) or more of corneal astigmatism. SETTING:Private practice, Bologna, Italy. DESIGN:Prospective case series. METHODS:Corneal astigmatism was measured using a Scheimpflug camera combined with...
journal_title：Journal of cataract and refractive surgery
pub_type： 杂志文章
doi：10.1016/j.jcrs.2014.01.046
更新日期：2014-10-01 00:00:00
abstract：PURPOSE:To investigate the prevalence of preoperative cataract surgery testing and consultation at a single United States teaching hospital. SETTING:Academic-affiliated Veterans Affairs Medical Center. DESIGN:Retrospective chart review. METHODS:This study included patients who received cataract surgery from 2014 to ...
journal_title：Journal of cataract and refractive surgery
pub_type： 杂志文章
doi：10.1097/j.jcrs.0000000000000153
更新日期：2020-06-01 00:00:00
abstract：PURPOSE:To assess the refractive accuracy of different formulas for intraocular lens (IOL) power calculation in eyes with keratoconus. SETTING:IRCCS Fondazione Bietti, Rome, Italy. DESIGN:Multicenter retrospective interventional study. METHODS:A consecutive series of eyes with keratoconus that had cataract surgery w...
journal_title：Journal of cataract and refractive surgery
pub_type： 杂志文章,多中心研究
doi：10.1016/j.jcrs.2018.11.029
更新日期：2019-05-01 00:00:00
abstract：PURPOSE:To ascertain whether the change in refraction caused by paired lamellating corneal incisions in cadaver eyes could be achieved in living eyes and whether wound healing influences this effect. SETTING:Virchow Hospital Eye Clinic, Humboldt University, Berlin, Germany. METHODS:This prospective study included 45 ...
journal_title：Journal of cataract and refractive surgery
pub_type： 杂志文章
doi：10.1016/s0886-3350(97)80342-2
更新日期：1997-03-01 00:00:00
abstract：:We report a case of a significant hyperopic shift 2 years after myopic photorefractive keratectomy with an interim of stability. The patient was an otherwise healthy man who reported a sudden change in vision when climbing to altitude. Medical considerations for refractive shifts should be looked at before retreatment...
journal_title：Journal of cataract and refractive surgery
pub_type： 杂志文章
doi：10.1016/j.jcrs.2006.09.028
更新日期：2007-02-01 00:00:00
abstract：:A 31-year-old female physician with bilateral myopia had unilateral myopic laser in situ keratomileusis in the right eye. The patient was overcorrected with the initial treatment and had 2 subsequent hyperopic treatments, resulting in central corneal irregularity. During the course of treatment, the patient was diagno...
journal_title：Journal of cataract and refractive surgery
pub_type： 杂志文章
doi：10.1016/s0886-3350(03)00471-1
更新日期：2003-11-01 00:00:00
abstract：PURPOSE:To compare the postoperative blood-aqueous barrier (BAB) breakdown induced by phacoemulsification with continuous curvilinear capsulorhexis (CCC) and by extracapsular cataract extraction (ECCE) with a linear capsulotomy. SETTING:Cataract and Refractive Surgery Research Unit, Department of Ophthalmology, St. Th...
journal_title：Journal of cataract and refractive surgery
pub_type： 杂志文章
doi：10.1016/s0886-3350(96)80160-x
更新日期：1996-01-01 00:00:00
abstract：:A multizone/multipass photorefractive keratectomy (MP-PRK) technique was used to treat 315 eyes with the 193 nm VISX 20/20 excimer laser. Algorithms were developed to treat the full range of myopia, including 170 low myopic eyes (-1.0 to -6.0 diopters [D]), 105 moderately myopic eyes (-6.0 to -10.0 D), and 40 highly m...
journal_title：Journal of cataract and refractive surgery
pub_type： 杂志文章
doi：10.1016/s0886-3350(13)80559-7
更新日期：1995-11-01 00:00:00
abstract：PURPOSE:To examine the optical quality of healthy presbyopic eyes before and after implantation of the pseudoaccommodating AcrySof ReSTOR Natural intraocular lens (IOL) (Alcon Laboratories) by measuring visual acuity and wavefront aberrations. SETTING:University of Valencia, Fernández-Vega Ophthalmological Institute, ...
journal_title：Journal of cataract and refractive surgery
pub_type： 杂志文章
doi：10.1016/j.jcrs.2008.01.017
更新日期：2008-05-01 00:00:00
abstract：PURPOSE:To evaluate the safety and efficacy of posterior continuous curvilinear capsulorhexis with optic capture n preventing secondary opacification of the visual axis in pediatric eyes having cataract surgery and intraocular lens (IOL) implantation. SETTING:Gimbel Eye Centre, Calgary, Alberta, Canada. METHOD:Poster...
journal_title：Journal of cataract and refractive surgery
pub_type： 杂志文章
doi：10.1016/s0886-3350(97)80049-1
更新日期：1997-01-01 00:00:00
abstract：PURPOSE:To determine the level of residual spherical aberration that gives the best objective and subjective quality of image after cataract surgery with intraocular lens (IOL) implantation. SETTING:Department of Ophthalmology, CHU Bretonneau, Tours, France. DESIGN:Cohort study. METHODS:Six months after microincisio...
journal_title：Journal of cataract and refractive surgery
pub_type： 杂志文章
doi：10.1016/j.jcrs.2010.12.056
更新日期：2011-06-01 00:00:00
abstract：PURPOSE:To report outcomes of secondary intraocular lens (IOL) implantation in the Infant Aphakia Treatment Study (IATS) SETTING:: Multicenter clinical practice DESIGN:: Secondary analysis of patients enrolled in a randomized clinical trial METHODS:: Details regarding all secondary IOL surgeries conducted in children e...
journal_title：Journal of cataract and refractive surgery
pub_type： 杂志文章
doi：10.1097/j.jcrs.0000000000000412
更新日期：2020-09-07 00:00:00
abstract：:We present a case of endocapsular hematoma, a rare form of intraocular hemorrhage that developed in a patient with pseudophakia receiving oral anticoagulants for previous mitral valve replacement and cerebrovascular disease. ...
journal_title：Journal of cataract and refractive surgery
pub_type： 杂志文章
doi：10.1016/j.jcrs.2005.07.011
更新日期：2006-01-01 00:00:00
abstract：PURPOSE:To examine the safety and efficacy of myopic keratomileusis in situ (automated lamellar keratoplasty) using an automated microkeratome. SETTING:Jules Stein Eye Institute and the Department of Ophthalmology, UCLA School of Medicine, Los Angeles, California. METHODS:A retrospective study was done on 135 consecu...
journal_title：Journal of cataract and refractive surgery
pub_type： 杂志文章
doi：10.1016/s0886-3350(96)80145-3
更新日期：1996-12-01 00:00:00
abstract：PURPOSE:To measure the change in visual acuity and vision-related quality of life in patients with both age-related cataract and bilateral age-related macular degeneration (AMD) after cataract surgery. SETTING:Department of Ophthalmology, Shanghai General Hospital, Shanghai Jiao Tong University, Shanghai, China. DESI...
journal_title：Journal of cataract and refractive surgery
pub_type： 杂志文章
doi：10.1016/j.jcrs.2014.09.046
更新日期：2015-06-01 00:00:00
abstract：PURPOSE:To compare the safety and efficacy of the new sodium hyaluronate viscoelastic, Microvisc, with those of Healon in routine phacoemulsification. SETTING:York Finch Eye Associates and York Finch General Hospital, Toronto, Ontario, Canada. METHODS:An unmasked, prospective, randomized clinical trial of 100 eyes in...
journal_title：Journal of cataract and refractive surgery
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1016/s0886-3350(97)80288-x
更新日期：1997-06-01 00:00:00
abstract：PURPOSE:To analyze anterior segment structure changes during accommodative stimuli after monofocal intraocular lens (IOL) implantation using 2 ultrasound biomicroscopy (UBM) systems. SETTING:Department of Ophthalmology, University of Verona, Verona, Italy. METHODS:Twenty-six eyes (23 patients) with 1 of 4 monofocal I...
journal_title：Journal of cataract and refractive surgery
pub_type： 杂志文章
doi：10.1016/j.jcrs.2008.02.018
更新日期：2008-06-01 00:00:00
abstract：PURPOSE:To compare the efficacy of heparin-surface-modified (HSM), poly(methyl methacrylate) (PMMA) posterior chamber intraocular lenses (IOLs) with that of unmodified PMMA IOLs in reducing postoperative complications caused by inflammatory reactions after extracapsular cataract extraction in an Asian population. SETT...
journal_title：Journal of cataract and refractive surgery
pub_type： 临床试验,杂志文章,多中心研究,随机对照试验
doi：10.1016/s0886-3350(96)80170-2
更新日期：1996-01-01 00:00:00
abstract：PURPOSE:To compare complication rates, visual acuity, and refractive outcomes of secondary intraocular lens (IOLs) implantation. SETTING:Department of Ophthalmology, Cullen Eye Institute, Baylor College of Medicine, Houston, Texas, USA. DESIGN:Retrospective case series. METHODS:All secondary IOLs placed by the anter...
journal_title：Journal of cataract and refractive surgery
pub_type： 杂志文章
doi：10.1016/j.jcrs.2016.12.024
更新日期：2017-03-01 00:00:00
abstract：:Three cases are described in which a curvilinear lucency in the corneal stroma signified a surgical thermal injury. The "shark fin" appearance represents focal shrinkage of tissue within the incisional tunnel. ...
journal_title：Journal of cataract and refractive surgery
pub_type： 杂志文章
doi：10.1016/j.jcrs.2004.11.034
更新日期：2005-03-01 00:00:00
abstract：PURPOSE:To evaluate the efficacy and safety of intracameral recombinant tissue plasminogen activator (rt-PA) application for fibrinolysis of fibrin formation after cataract surgery in children. SETTING:Johann Wolfgang Goethe-University, Department of Ophthalmology, Frankfurt am Main, Germany. METHODS:This study compr...
journal_title：Journal of cataract and refractive surgery
pub_type： 临床试验,杂志文章
doi：10.1016/s0886-3350(99)80083-2
更新日期：1999-03-01 00:00:00
abstract：:A simple technique for the accurate surgical alignment of toric phakic and aphakic intraocular lenses (IOLs) is described. The mathematical relationship between toric misalignment and cylinder error is reviewed to demonstrate the importance of toric lens alignment in the setting of increased rotational stability with ...
journal_title：Journal of cataract and refractive surgery
pub_type： 杂志文章
doi：10.1016/j.jcrs.2008.04.041
更新日期：2008-10-01 00:00:00
abstract：PURPOSE:To compare the incidence of diffuse lamellar keratitis (DLK) after laser in situ keratomileusis (LASIK) with flap creation using the 15 kHz (FS15), 30 kHz (FS30), or 60 kHz (FS60) femtosecond laser. SETTING:University-based academic practice, Ann Arbor, Michigan, USA. DESIGN:Retrospective comparative case ser...
journal_title：Journal of cataract and refractive surgery
pub_type： 杂志文章
doi：10.1016/j.jcrs.2010.09.003
更新日期：2010-11-01 00:00:00
