Abstract:
:Anxious-retarded depression is a two-dimensionally defined subcategory of depression based on high scores for both anxiety and retardation. The anxious-retarded subcategory is related to melancholia as defined by DSM-IV. Patients with this diagnosis exhibit elevated plasma arginine vasopressin (AVP) and a high correlation between plasma vasopressin and cortisol, which suggests vasopressinergic overactivation of the hypothalamus-pituitary-adrenal (HPA) axis. In this report, we present the multidimensional derivation of the anxious-retarded subcategory from DSM-IV melancholia, and a second step in the validation of this anxious-retarded subcategory by exploring its relation to family history of depression. The patient sample comprised 89 patients with major depression and encompassed 66 patients investigated previously regarding plasma AVP and cortisol. All patients were rated for the following three dimensions of psychopathology: autonomic dysregulation (anxiety), motivational inhibition (retardation), and emotional dysregulation, as well as for family history of depression. The dependence of DSM-IV melancholia on the sum scores and the dichotomized scores on the three dimensions was investigated by multiple logistic regression. Thereafter, the dependence of the family history for depression on the same parameters was also investigated. The melancholic subcategory depended on the interaction between the sum scores, as well as on the interaction between the dichotomized scores for anxiety and retardation that constitute the anxious-retarded subcategory. Family history for depression depended only on the interaction of the dichotomized scores, and thus on the anxious-retarded subcategory.
journal_name
Psychiatry Resjournal_title
Psychiatry researchauthors
de Winter RF,Zwinderman KH,Goekoop JGdoi
10.1016/j.psychres.2004.03.010subject
Has Abstractpub_date
2004-06-30 00:00:00pages
111-9issue
1-2eissn
0165-1781issn
1872-7123pii
S0165178104000824journal_volume
127pub_type
杂志文章abstract::Since the magnitude of the first-night effect has been shown to be a function of medical conditions and of settings in which polysomnographies are performed, it is essential to evaluate the habituation phenomenon in each case in order to determine the optimal recording methodology. A first-night effect was evidenced i...
journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/s0165-1781(03)00185-9
更新日期:2003-09-30 00:00:00
abstract::Although deep grey matter (GM) involvement in multiple sclerosis (MS) is well documented, in-vivo multi-parameter magnetic resonance imaging (MRI) studies and association with detailed cognitive measures are limited. We investigated volumetric, diffusion and perfusion metrics in thalamus, hippocampus, putamen, caudate...
journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/j.pscychresns.2015.10.004
更新日期:2015-12-30 00:00:00
abstract::Patients with affective disorders frequently report problems with attention, concentration and memory, although little research has investigated subjective cognitive complaints relative to objective neuropsychological deficits. We compared subjective (self-rated) cognition and objective (clinician-rated) neuropsycholo...
journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/j.psychres.2004.12.009
更新日期:2005-07-15 00:00:00
abstract::The aim of the present study was to evaluate subject and informant factors affecting the validity of the family history for dementia and depression. Relatives of patients and control subjects (n = 531) were interviewed directly. At least one 'significant' other provided family history information on every interviewed ...
journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/s0165-1781(97)00058-9
更新日期:1997-08-08 00:00:00
abstract::Psychosis induced by the use of amphetamine or methamphetamine leads to dramatic symptoms and frequent readmissions and poses diagnostic challenges. Earlier studies have often relied on history taking and/or urine samples to reveal drug use. The aim of this study was to compare the psychotic symptoms of two groups: (1...
journal_title:Psychiatry research
pub_type: 杂志文章,多中心研究
doi:10.1016/j.psychres.2012.09.023
更新日期:2013-03-30 00:00:00
abstract::Emotion dysregulation and hyperreactivity are considered central features of Borderline Personality Disorder (BPD). We assumed that such emotion dysregulation is also reflected in increased crying behavior of these patients and, consequently, hypothesized that BPD patients (N = 62), compared to Cluster C personality d...
journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/j.psychres.2019.01.024
更新日期:2019-03-01 00:00:00
abstract::N-Acetyl-aspartate (NAA), a marker of neuronal integrity, has been found to be reduced in frontal regions in schizophrenia. However, the impact of antipsychotic drug type on NAA has not been carefully evaluated. We studied outpatients with schizophrenia/schizoaffective disorders chronically treated with haloperidol or...
journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/s0925-4927(01)00102-0
更新日期:2001-10-01 00:00:00
abstract::The World Health Organization ranks obsessive compulsive disorder (OCD) among the leading causes of worldwide medical disability. Affecting approximately 3% of the population, OCD, with its damaging effect on psychosocial function, is among the most severe and impairing of mental disorders. In Diagnostic and Statistic...
journal_title:Psychiatry research
pub_type:
doi:10.1016/j.psychres.2014.12.002
更新日期:2015-05-30 00:00:00
abstract::A significant association between anxiety and depersonalization has been found in healthy controls and psychiatric patients irrespective of underlying conditions. Although patients with depersonalization disorder (DPD) often have a history of severe anxiety symptoms, clinical observations suggest that the relation bet...
journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/j.psychres.2011.12.017
更新日期:2012-05-15 00:00:00
abstract::Abnormalities in the neurohypophyseal system have been reported in depression. This study aimed to investigate serum oxytocin levels in patients with depression and the effects of gender and antidepressant treatment on these levels. Serum oxytocin levels were measured before and after treatment with antidepressant dru...
journal_title:Psychiatry research
pub_type: 临床试验,杂志文章
doi:10.1016/j.psychres.2008.06.034
更新日期:2009-10-30 00:00:00
abstract::Depressive symptoms are associated with deficits in objectively-rated detail and specificity in autobiographical future thinking for personally-relevant events. However, how depressive symptoms might affect the subjective, phenomenal characteristics of future thinking in general is not well understood. This study exam...
journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/j.psychres.2018.12.100
更新日期:2019-03-01 00:00:00
abstract::Past research has found that deficits in insight into illness are related to executive deficits in schizophrenia. This study further explores this relationship with the utilization of an ecologically-valid battery of executive tests. The study included 21 patients with schizophrenia who were administered the Behaviour...
journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/j.psychres.2006.09.012
更新日期:2007-05-30 00:00:00
abstract::There is a growing recognition of the importance of encouraging patients with mental health problems to become more active as an efficacious strategy to reduce the disability-associated burden. The aim of the current study was to investigate if there are differences in quality of life (QoL) outcomes between people wit...
journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/j.psychres.2017.08.041
更新日期:2017-12-01 00:00:00
abstract::The aim of this study was to evaluate the relationships between coping strategies and four dimensions of quality of life (QOL) (physical, psychological, social relations and environment) among military wives. We examined these links six months after the military operation termed Protective Edge. Data were collected fr...
journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/j.psychres.2017.04.037
更新日期:2017-08-01 00:00:00
abstract::The utility of non-invasive brain stimulation techniques to alleviate resistant delusions in schizophrenia is an under-researched area. In this study, we report the effectiveness of alpha transcranial alternating current stimulation (tACS) targeting the medial prefrontal cortex in ameliorating persistent delusions. Tw...
journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/j.psychres.2020.113106
更新日期:2020-08-01 00:00:00
abstract::Psychotic-like experiences (PLEs) are sub-psychotic expressions of the psychosis continuum. Several studies have suggested multifactorial models, including a bifactor model, of the putative PLEs assessed with the popular Community Assessment of Psychic Experiences (CAPE) questionnaire. Our confirmatory results in a ge...
journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/j.psychres.2015.12.023
更新日期:2016-01-30 00:00:00
abstract::Major depressive disorder is associated with lower medial prefrontal cortex volumes. The role that gender might play in moderating this relationship and what particular medial prefrontal cortex subregion(s) might be implicated is unclear. Magnetic resonance imaging was used to assess dorsal, ventral, and anterior cing...
journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/j.pscychresns.2015.06.005
更新日期:2015-08-30 00:00:00
abstract::Aim of this study consisted in assessing the 24-h heart rate variability (HRV), a measure of autonomic nervous system (ANS) imbalance, in 21 adolescents with functional hypothalamic amenorrhea (FHA, 11 normogonadotropic, N-FHA, and 10 hypogonadotropic, Hy-FHA) compared to 21 patients with anorexia nervosa (AN) and 21 ...
journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/j.psychres.2013.11.012
更新日期:2014-02-28 00:00:00
abstract::Autobiographical amnesia assessments in depression need to account for normal changes in consistency over time, contribution of mood and type of memories measured. We report herein validation studies of the Columbia Autobiographical Memory Interview - Short Form (CAMI-SF), exclusively used in depressed patients receiv...
journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/j.psychres.2011.12.010
更新日期:2012-05-15 00:00:00
abstract::Recent magnetic resonance imaging (MRI) studies using diffusion tensor imaging (DTI) have suggested reduced fractional anisotropy (FA) in the white matter (WM) of the brain in patients with schizophrenia. We tried to examine whether such reduction in FA exists and whether such changes in FA progress in an age-dependen...
journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/j.pscychresns.2006.09.004
更新日期:2007-02-28 00:00:00
abstract::The aim of our study was to investigate whether patients with obsessive-compulsive disorder (OCD) have impaired incidental memory for frequency. Fifty-four subjects (27 OCD patients and 27 matched control subjects) performed a task assessing estimation of occurrence of previously heard words. Performance on this task ...
journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/s0165-1781(01)00322-5
更新日期:2001-11-30 00:00:00
abstract::To date, there are no data on quality of life (QOL) and its correlates in homeless Chinese patients with psychiatric disorders. This study aimed to compare QOL between homeless and non-homeless patients with psychiatric disorders in China. A total of 278 homeless and 222 non-homeless patients matched in age and gender...
journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/j.psychres.2017.01.016
更新日期:2017-03-01 00:00:00
abstract::Social anxiety disorder symptoms are generally proposed to be related to broad temperamental vulnerabilities (e.g., a low level of approach and high level of avoidance temperament), specific psychological vulnerabilities (e.g., fears of negative and positive evaluation), and additional disorders (e.g., major depressiv...
journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/j.psychres.2017.01.073
更新日期:2017-04-01 00:00:00
abstract::Negative symptoms have been suggested to have a greater impact on real-world functioning in schizophrenia than other symptoms. We aimed to examine the relationship of specific negative symptoms components ("expressive deficits" - DE - which include alogia and blunted affect, and "avolition" - AA - which includes amoti...
journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/j.psychres.2014.04.018
更新日期:2014-08-30 00:00:00
abstract::The current study aimed to explore Israelis' state anxiety due to a Syrian-Israeli incident that occurred on February 10, 2018, when an Israeli F-16 fighter jet was shot down by Syrian air defense forces. In line with the "looming vulnerability" model which emphasizes the importance of the dynamic nature of psychologi...
journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/j.psychres.2018.10.072
更新日期:2018-12-01 00:00:00
abstract::A comprehensive study was conducted 8 months after the 2010 Yushu earthquake to assess the prevalence of posttraumatic stress disorder (PTSD) among medical rescuers and the rescuers' quality of life. Additionally, the study examines differences between local and supporting forces, as well as the relationship between P...
journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/j.psychres.2015.09.047
更新日期:2015-12-15 00:00:00
abstract::Brain morphology was assessed qualitatively in CT scans of 21 patients with panic disorder and 21 normal control subjects. Patients showed significant bilateral enlargement of frontal cerebrospinal fluid (CSF) spaces. These findings suggest that alterations in brain morphology are involved in the etiology of panic dis...
journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/s0925-4927(97)00065-6
更新日期:1997-12-30 00:00:00
abstract::The seven-factor model of personality developed by Cloninger and colleagues describes personality as a function of developmental aspects of character superimposed on heritable dimensions of temperament. The objective of this study was to determine whether this model could be applied to early childhood. We tested a pre...
journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/s0165-1781(02)00008-2
更新日期:2002-04-15 00:00:00
abstract::Transdiagnostic approach has a long history in neuroimaging, predating its recent ascendance as a paradigm for new psychiatric nosology. Various psychiatric disorders have been compared for commonalities and differences in neuroanatomical features and activation patterns, with different aims and rationales. This revie...
journal_title:Psychiatry research
pub_type: 杂志文章,评审
doi:10.1016/j.psychres.2019.01.026
更新日期:2019-07-01 00:00:00
abstract::We studied semantic priming in 20 major depressive subjects. The methodology used was a visual lexical decision task. Semantic priming is the facilitation of target word recognition (shortening of response time) by the prior presentation of a semantically related context (a prime word). It relies on semantic processin...
journal_title:Psychiatry research
pub_type: 杂志文章
doi:10.1016/s0165-1781(97)00155-8
更新日期:1998-03-20 00:00:00