Novel interleukin 1beta polymorphism increased the risk of gastric cancer in a Korean population.

abstract：:We report two cirrhotic patients with gastric antral vascular ectasia (GAVE) in whom chronic blood loss presented a major problem. Case 1, a 69-year-old man, had alcoholic liver cirrhosis, and case 2, a 75-year-old woman, had liver cirrhosis associated with hepatitis C virus. The patients required repeated blood trans...

journal_title：Journal of gastroenterology

authors： Yamada M,Nishimura D,Hoshino H,Katada N,Sano H,Kato K

更新日期：1998-08-01 00:00:00

abstract：:The gastrointestinal epithelium is a unique model for the study of mammalian stem cells. Not only does it have a highly stereotypical organization, its remarkable rate of self-renewal provides a daily readout of stem cell activity. The past decade has seen a major investment in developing technologies dedicated to rev...

journal_title：Journal of gastroenterology

authors： Lin SA,Barker N

更新日期：2011-09-01 00:00:00

abstract：:To investigate the role played by cytokines in chronic pancreatitis, we examined serum levels of interleukin-1 beta (IL-1 beta) and interleukin-6 (IL-6) by radioimmunoassay (RIA) and enzyme-linked immunosorbent assay (ELISA) in 33 patients with definitively diagnosed chronic pancreatitis. All the patients, who had rec...

journal_title：Journal of gastroenterology

authors： Bamba T,Yoshioka U,Inoue H,Iwasaki Y,Hosoda S

更新日期：1994-06-01 00:00:00

abstract：BACKGROUND:Matrix metalloproteinases (MMPs) are one of the major classes of proteolytic enzymes involved in tumor invasion and metastasis, being inhibited by naturally occurring tissue inhibitors of metalloproteinases (TIMPs). In this study, we examined the expression of MMP-2, MMP-9, membrane-type 1 (MT1)-MMP, TIMP-1,...

journal_title：Journal of gastroenterology

authors： Shim KN,Jung SA,Joo YH,Yoo K

更新日期：2007-02-01 00:00:00

abstract：BACKGROUND:Hepatitis C virus (HCV) core protein is known to cause oxidative stress and alter apoptosis pathways. However, the apoptosis results are inconsistent, and the real significance of oxidative stress is not well known. The aim of this study was twofold. First, we wanted to confirm whether core-induced oxidative...

journal_title：Journal of gastroenterology

authors： Hara Y,Hino K,Okuda M,Furutani T,Hidaka I,Yamaguchi Y,Korenaga M,Li K,Weinman SA,Lemon SM,Okita K

更新日期：2006-03-01 00:00:00

abstract：BACKGROUND:Circular RNAs (circRNAs) act as vital regulators of gene expression in a variety of cancers. However, the role of circRNAs in gastric cancer (GC) remains largely unexplored. Herein, we identified that circTMEM87A sponges miR-142-5p to promote GC progression through up-regulating ULK1 expression. METHODS:The...

journal_title：Journal of gastroenterology

authors： Wang H,Sun G,Xu P,Lv J,Zhang X,Zhang L,Wang S,Cao J,Xia Y,Xuan Z,Li B,Huang X,Jiang T,Fang L,Xu Z

更新日期：2020-11-06 00:00:00

abstract：BACKGROUND:Oropharyngeal dysphagia (OD) is a major gastrointestinal motility disorder that causes severe nutritional and respiratory complications in elderly and neurological patients. In an earlier study, we found that stimulation of pharyngeal sensory neurons by capsaicinoids acting on transient receptor potential va...

journal_title：Journal of gastroenterology

authors： Rofes L,Arreola V,Martin A,Clavé P

更新日期：2014-12-01 00:00:00

abstract：BACKGROUND:Contrast-enhanced echocardiography (CEE) using agitated saline can detect intrapulmonary vasodilatation (IPVD) in patients with hepatopulmonary syndrome (HPS). We estimated the pulmonary transit time of erythrocytes (PTT) by CEE, using microbubbles, and studied its relationship to arterial oxygenation in chr...

journal_title：Journal of gastroenterology

authors： Katsuta Y,Honma H,Zhang XJ,Ohsuga M,Komeichi H,Shimizu S,Katoh Y,Miura H,Satomura K,Aramaki T,Takano T

更新日期：2005-01-01 00:00:00

abstract：:We present a patient with complication of huge hepatic subcapsular hematoma after extracorporeal shock wave lithotripsy (ESWL) for pancreatic lithotripsy. The hematoma measured 78-110mm. Angiography showed a subcapsular hematoma, rather than a hematoma in the liver. In the arterial phase, the distal end of the small v...

journal_title：Journal of gastroenterology

authors： Hirata N,Kushida Y,Ohguri T,Wakasugi S,Kojima T,Fujita R

更新日期：1999-12-01 00:00:00

abstract：:Perianal fistulae are frequently seen complications in Crohn's disease. Although surgical procedures such as Seton's method have been devised, many patients still suffer from fistulae that are resistant to conventional therapy. We administered oral adsorbent to a patient with disease Crohn's who had a complicated peri...

journal_title：Journal of gastroenterology

authors： Tsujikawa T,Araki Y,Makino J,Uda K,Ihara T,Sasaki M,Fujiyama Y,Bamba T

更新日期：2000-01-01 00:00:00

abstract：BACKGROUND:Gastric cancer stem cells (CSCs), which require activation of Wnt signaling to maintain their self-renewal and tumorigenicity, are proposed to be critical targets for effective therapy of gastric carcinomas. Gene therapies that are delivered by adenovirus of serotype 5 (Ad5) or chimeric 5/35(Ad5/35) adenovir...

journal_title：Journal of gastroenterology

authors： Wang B,Liu J,Ma LN,Xiao HL,Wang YZ,Li Y,Wang Z,Fan L,Lan C,Yang M,Hu L,Wei Y,Bian XW,Chen D,Wang J

更新日期：2013-07-01 00:00:00

abstract：BACKGROUND:The aim of this study was to determine whether leptin and insulin resistance (IR) showed differences between steatotic patients with and without elevated serum transaminases. METHODS:The study included 32 patients with fatty liver and high serum transaminase level (group I), 31 patients with fatty liver and...

journal_title：Journal of gastroenterology

authors： Serin E,Ozer B,Gümürdülü Y,Kayaselçuk F,Kul K,Boyacioğlu S

更新日期：2003-01-01 00:00:00

abstract：BACKGROUND:The gap junction (GJ) plays important roles in the maintenance of tissue homeostasis, the control of cell growth and differentiation, and the prevention of experimental hepatocarcinogenesis. In this study, we examined the relationship between the expression of the GJ protein connexin (Cx) 32 in 24 human hepa...

journal_title：Journal of gastroenterology

authors： Nakashima Y,Ono T,Yamanoi A,El-Assal ON,Kohno H,Nagasue N

更新日期：2004-08-01 00:00:00

abstract：:Fulminant hepatic failure (FHF) usually has a fatal prognosis without liver transplantation. We describe the case of a woman who developed FHF, and was evaluated as a candidate for liver transplantation, but who was cured without transplantation through intensive medical care that included glucagon-insulin therapy, me...

journal_title：Journal of gastroenterology

authors： Masuhara M,Yagawa T,Aoyagi M,Suzuki C,Sakaguchi E,Segawa M,Hironaka K,Kayano K,Tamura F,Seguchi M,Soejima Y,Murakami F,Sakaida I,Tateishi A,Fukumoto Y,Okita K

更新日期：2001-05-01 00:00:00

abstract：BACKGROUND:Patients with primary biliary cirrhosis (PBC) exhibit a variety of clinical manifestations and patterns of disease progression. The aim of this study was to identify genetic determinants of PBC progression. METHODS:A total of 52 tag single nucleotide polymorphisms (SNPs) of 11 candidate genes involved in re...

journal_title：Journal of gastroenterology

authors： Inamine T,Higa S,Noguchi F,Kondo S,Omagari K,Yatsuhashi H,Tsukamoto K,Nakamura M

更新日期：2013-10-01 00:00:00

abstract：BACKGROUND:High serum immunoglobulin G4 (IgG4) levels and IgG4-positive plasma cell infiltration are characteristic of type 1 autoimmune pancreatitis (AIP). It is unclear whether innate immunity is a cause of type 1 AIP; the possible involvement of microbial infection has been suggested in its pathogenesis. To clarify ...

journal_title：Journal of gastroenterology

authors： Fukui Y,Uchida K,Sakaguchi Y,Fukui T,Nishio A,Shikata N,Sakaida N,Uemura Y,Satoi S,Okazaki K

更新日期：2015-04-01 00:00:00

abstract：:In Japan, Kaposi's sarcoma (KS) is a very rare neoplasm. However, it does occur as one of the complications in patients with acquired immunodeficiency syndrome (AIDS). AIDS-related KS commonly involves the skin, lymph nodes, and gastrointestinal tract. Hepatic KS is sometimes observed in AIDS patients at autopsy, but ...

journal_title：Journal of gastroenterology

authors： Tanaka T,Masuda G,Takechi A,Kobayashi H,Tanaka S,Koike M,Hattori N

更新日期：1995-04-01 00:00:00

abstract：:A 27-year-old woman with a 9-year history of ulcerative colitis involving the entire colon was admitted to our hospital in August 1992 because of bloody stools and left lower abdominal pain. She had been treated with sulfasalazine since 1983 and the colitis had been clinically quiescent or mild for 7 years. She had al...

journal_title：Journal of gastroenterology

authors： Seo M,Okada M,Osamura S,Hara S,Umeno T,Maeshiro K,Yamada Y,Yuh K

更新日期：1997-02-01 00:00:00

abstract：:We encountered a patient with a ciliated hepatic foregut cyst with accompanying liver cirrhosis, which was hard to distinguish from well-differentiated hepatocellular carcinoma. A lesion 2 cm in diameter was found in the subcapsular region of the medial segment of the liver. It was slightly hypoechoic on ultrasonograp...

journal_title：Journal of gastroenterology

authors： Murakami T,Imai A,Nakamura H,Tsuda K,Kanai T,Wakasa K

更新日期：1996-06-01 00:00:00

abstract：BACKGROUND:Although pancreatic duct guidewire placement (P-GW) for achieving selective biliary cannulation is reported to be effective in patients in whom endoscopic retrograde cholangiopancreatography (ERCP) is difficult, this technique entails a possible increased risk of post-ERCP pancreatitis. We conducted a prospe...

journal_title：Journal of gastroenterology

authors： Ito K,Fujita N,Noda Y,Kobayashi G,Obana T,Horaguchi J,Takasawa O,Koshita S,Kanno Y,Ogawa T

更新日期：2010-11-01 00:00:00

abstract：:A case of life-threatening lower gastrointestinal hemorrhage from Crohn's disease is reported. Several promising studies have recently been published that describe superselective embolization for the treatment of massive lower gastrointestinal hemorrhage in patients with bleeding colonic diverticular disease and angio...

journal_title：Journal of gastroenterology

authors： Kazama Y,Watanabe T,Akahane M,Yoshioka N,Ohtomo K,Nagawa H

更新日期：2005-12-01 00:00:00

abstract：BACKGROUND:Once-daily, orally administered, co-formulated glecaprevir (NS3/4A protease inhibitor) and pibrentasvir (NS5A inhibitor) (G/P) demonstrated pangenotypic activity and high sustained virologic response (SVR) rates in studies outside Japan. Here we report safety and efficacy in a subset of Japanese patients wit...

journal_title：Journal of gastroenterology

authors： Kumada H,Watanabe T,Suzuki F,Ikeda K,Sato K,Toyoda H,Atsukawa M,Ido A,Takaki A,Enomoto N,Kato K,Alves K,Burroughs M,Redman R,Pugatch D,Pilot-Matias TJ,Krishnan P,Oberoi RK,Xie W,Chayama K

更新日期：2018-04-01 00:00:00

abstract：:A patient with hepatitis C virus (HCV)-related liver cirrhosis and hepatocellular carcinoma (HCC) was treated successfully with an orthotopic liver transplantation (OLT) followed by interferon therapy. The 36-year-old Japanese man was diagnosed as having liver cirrhosis in 1983. HCC was detected in 1991, and by 1994, ...

journal_title：Journal of gastroenterology

authors： Shibata M,Yanaga K,Morizane T,Yanagawa T,Hirakawa M,Ueno Y,Esquivel CO,Mitamura K

更新日期：2003-01-01 00:00:00

abstract：BACKGROUND:Innate immunity mechanisms have been shown to play a paramount role in organ transplantation. Our aim was to investigate the hypothesis that activation of the interferon system may affect clinically relevant outcomes, such as acute rejection and/or early fibrosis progression, after liver transplantation. ME...

journal_title：Journal of gastroenterology

authors： Minisini R,Giarda P,Grossi G,Bitetto D,Toniutto P,Falleti E,Avellini C,Occhino G,Fabris C,Pirisi M

更新日期：2011-11-01 00:00:00

abstract：BACKGROUND:We carried out this study to evaluate the association between regulatory T cells (Treg) and prognosis and progression after cryoablation in patients with hepatitis-B virus-related hepatocellular carcinoma. METHODS:Peripheral Treg frequency in 111 patients with hepatocellular carcinoma (HCC) was detected by ...

journal_title：Journal of gastroenterology

authors： Zhou L,Fu JL,Lu YY,Fu BY,Wang CP,An LJ,Wang XZ,Zeng Z,Zhou CB,Yang YP,Wang FS

更新日期：2010-09-01 00:00:00

abstract：BACKGROUND:Long-term nucleos(t)ide analogue (NA) therapy for chronic hepatitis B (CHB) patients has been reported to reduce the risk of hepatocellular carcinoma (HCC) development. However, survival rates and causes of death in CHB patients either treated or not treated with NA therapy are unclear. Therefore, we investi...

journal_title：Journal of gastroenterology

authors： Tada T,Kumada T,Toyoda H,Kiriyama S,Tanikawa M,Hisanaga Y,Kanamori A,Kitabtake S,Ito T

更新日期：2015-07-01 00:00:00

abstract：:A case of Dieulafoy's vascular malformation of the jejunum treated by laparoscopic surgery is described. The patient was a 31-year-old-woman who had complained of melena and had severe anemia needing blood transfusion. Angiography revealed microaneurysms and hypervascularity of the jejunum in the area between the firs...

journal_title：Journal of gastroenterology

authors： Mino A,Ogawa Y,Ishikawa T,Uchima Y,Yamazaki M,Nakamura S,Yukawa T,Matsumoto T,Arakawa T,Hirakawa K

更新日期：2004-01-01 00:00:00

abstract：:Although polycystic liver disease (PLD) is known to be associated with autosomal dominant polycystic kidney disease, a finding of PLD with pancreatic ductal adenocarcinoma is extremely rare. We have experienced one such case of a ductal adenocarcinoma of the pancreas in a patient with Potter type III cystic disease of...

journal_title：Journal of gastroenterology

authors： Sakurai Y,Shoji M,Matsubara T,Ochiai M,Funabiki T,Urano M,Mizoguchi Y,Fuwa N

更新日期：2001-06-01 00:00:00

abstract：:We investigated the effect of intravenous infusions of the therapeutically available amino acid solutions Moripron and Morihepamin (Roussel Morishita, Osaka, Japan) on gallbladder contraction and cholecystokinin (CCK) release in healthy male volunteers. Plasma CCK levels were measured by radioimmunoassay, using the an...

journal_title：Journal of gastroenterology

authors： Shirohara H,Tabaru A,Otsuki M

更新日期：1996-08-01 00:00:00

abstract：:We aimed to determine the safety and feasibility of an alternative postoperative oral intake protocol for Japanese patients who had had oncological colorectal surgery, with the goal of shortening the length of postoperative stay to the same level as that in Western countries. The subjects of the study were 42 consecut...

journal_title：Journal of gastroenterology

authors： Kawamura YJ,Uchida H,Watanabe T,Nagawa H

更新日期：2000-01-01 00:00:00