Mechanisms of antibiotic neurotoxicity in renal failure.

Abstract:

:Neurological complications of antibiotics are relatively common in renal failure. Central nervous system neurotoxicity due to penicillin and beta-lactam antibiotics is best documented with fewer accounts of ototoxicity, peripheral nerve toxicity and neuromuscular blockade. In the context of risk stratification, the goal of this review is to explore the mosaic of factors in renal impairment that may contribute to susceptibility to antibiotic neurotoxicity. Improved knowledge of the pathogenesis of these formidable adverse events among the renal failure subjects should help prevent antibiotic neurotoxicity in the future.

authors

Chow KM,Szeto CC,Hui AC,Li PK

doi

10.1016/j.ijantimicag.2003.11.004

subject

Has Abstract

pub_date

2004-03-01 00:00:00

pages

213-7

issue

3

eissn

0924-8579

issn

1872-7913

pii

S0924857903004011

journal_volume

23

pub_type

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