Abstract：
:Partially purified human ovarian follicular fluid peptide (hGF2) was administered during follicular phase in 5 bonnet monkeys. In control as well as hGF2-injected animals, ovulation was synchronized by treatment with FSH, Pergonal and hCG. All the 5 control bonnet monkeys showed plasma estradiol peak followed by increased progesterone levels. In 4 out of 5 hGF2-injected animals, plasma progesterone levels were drastically reduced. Plasma estradiol levels were decreased only in 3 animals in which amenorrhea was observed. These data reveal that hGF2 injection disrupted ovarian function in bonnet monkeys.
journal_name
Contraceptionjournal_title
Contraceptionauthors
Nandedkar TD,Shahid JK,Kholkute SD,Darpe MB,Moodbidri SBdoi
10.1016/0010-7824(92)90060-7subject
Has Abstractpub_date
1992-04-01 00:00:00pages
379-85issue
4eissn
0010-7824issn
1879-0518pii
0010-7824(92)90060-7journal_volume
45pub_type
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