Abstract:
:The translocon is responsible for the translocation of proteins across the membrane of the endoplasmic reticulum into its lumen, whereas the exocyst acts at the other end of the secretory pathway, tethering secretory vesicles to the sites of exocytosis. Here, we discuss three independent lines of evidence that indicate surprising genetic, physical and functional interactions between the two complexes. Although much of the existing evidence is rather preliminary in nature, these interactions might serve to coordinate the biosynthetic capacity of the cell with the function of the secretory machinery.
journal_name
Trends Cell Bioljournal_title
Trends in cell biologyauthors
Guo W,Novick Pdoi
10.1016/j.tcb.2003.12.008subject
Has Abstractpub_date
2004-02-01 00:00:00pages
61-3issue
2eissn
0962-8924issn
1879-3088pii
S0962-8924(03)00307-6journal_volume
14pub_type
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