Abstract:
:The aim of the study was to evaluate two bioresorbable polylactic acid (PLA) filler materials in a guided bone regeneration (GBR) model system. The first was Polyfibre, a fibrous PLA filler material. Polyfoam, the second material tested, consisted of a spongy PLA filler material. In each group there were eight rabbits. In test rabbits a flap was raised uncovering the calvaria. A hemispherical PLA dome was filled with Polyfibre or Polyfoam material and periphereal blood and anchored onto the calvaria. Eight rabbits with the same domes, filled with blood alone, served as controls. The rabbits were sacrificed at 1 or 2 months. Histomorphometric measurements of regenerated total tissue volume, bone height and bone volume were carried out in undecalcified sections under a light microscope. At 1 month the totally filled volume attained 87% (range 82-91) in the fibre group, including 25% (23-27) fibres, 87% (85-95) in the foam group, including 15% (15-16) foam, and 55% (16-100) in the controls. The volume of mineralized bone was 12% (7-15) in the fibre group, 15% (12-18) in the foam group and 6% (1-11) in control domes. Bone height attained 48% (27-79) in the fibre group, 37% (31-58) in the foam group and 45% (14-67) in the control group. At 2 months, tissue volume attained 86% (85-87) including 26% (22-29) fibres, bone volume attained 13% (7-21) and bone height attained 56% (42-78) in the Polyfibre group. In the Polyfoam group, they were 83% (55-99) including 18% (15-19) foam, 13% (7-24) and 49% (29-74). In control domes, tissue volume was 82% (35-100), bone volume 20% (9-27) and bone height 86% (60-100). The Polyfibre and Polyfoam material was excellently integrated. No adverse reactions were found in the surrounding tissues. Direct bone apposition was observed onto the material. In conclusion, Polyfibre and Polyfoam material had a positive effect on initial bone and tissue formation but was a hindrance to increasing tissue volume, bone volume or bone height at 2 months compared to control specimens. The Polyfibre and Polyfoam material provoked no adverse reactions in the surrounding tissues and allowed for extensive angiogenesis.
journal_name
Clin Oral Implants Resjournal_title
Clinical oral implants researchauthors
Wallkamm B,Schmid J,Hämmerle CH,Gogolewski S,Lang NPdoi
10.1046/j.0905-7161.2003.00930.xsubject
Has Abstractpub_date
2003-12-01 00:00:00pages
734-42issue
6eissn
0905-7161issn
1600-0501pii
930journal_volume
14pub_type
杂志文章abstract::The aim of this study was to analyse the clinical outcome of two different surgical methods for the reconstruction of narrow edentulous ridges before implant installation: guided bone regeneration with e-PTFE membranes and autologous bone chips or grafting of autologous bone blocks without e-PTFE membranes. Thirty par...
journal_title:Clinical oral implants research
pub_type: 临床试验,杂志文章
doi:10.1034/j.1600-0501.1999.100404.x
更新日期:1999-08-01 00:00:00
abstract:OBJECTIVES:The aim of this controlled in vitro study was to identify and quantify up to 38 microbial species penetrating through the screw-retained implant prostheses with different sealing materials. MATERIAL AND METHODS:Sixty morse cone implants were restored with single-unit screw-retained prostheses. All the compo...
journal_title:Clinical oral implants research
pub_type: 杂志文章
doi:10.1111/clr.12790
更新日期:2017-02-01 00:00:00
abstract::The aim of this in vitro study was to determine whether the sinus mucosa holds cells with an osteogenic potential. Frozen sections of sinus mucosa from three adult pigs were investigated for the expression of STRO-1, a marker of mesenchymal progenitor cells, and alkaline phosphatase activity, an enzyme expressed by ce...
journal_title:Clinical oral implants research
pub_type: 杂志文章
doi:10.1111/j.1600-0501.2004.01062.x
更新日期:2004-10-01 00:00:00
abstract:BACKGROUND:Cement-retained fixed implant-supported restorations involve the risk of excess cement, which can associate peri-implantitis. In connection with routine therapy using a methacrylate cement (Premier Implant Cement, Premier(®) Dental Products Company, Plymouth Meeting, PA, USA) to retain fixed implant-supporte...
journal_title:Clinical oral implants research
pub_type: 杂志文章
doi:10.1111/clr.12173
更新日期:2014-07-01 00:00:00
abstract:OBJECTIVES:To compare the effectiveness of free-handed (FH), pilot-drill guided (PG) and fully guided (FG) implant surgery by means of the apical global deviation (AGD) in relation to the additional financial cost and time spent. MATERIALS AND METHODS:Thirty-three partially edentulous patients in need of ≥2 implants i...
journal_title:Clinical oral implants research
pub_type: 杂志文章,随机对照试验
doi:10.1111/clr.13399
更新日期:2019-02-01 00:00:00
abstract::This paper presents the Orthosystem (Institute Straumann, Waldenburg/ Switzerland), a new endosseous orthodontic implant anchor system for palatal anchorage. The Orthosystem may replace compliance dependent extraoral anchoring aids for orthodontics and makes a bonding of well aligned mandibular dentition and it's use ...
journal_title:Clinical oral implants research
pub_type: 杂志文章
doi:10.1034/j.1600-0501.1996.070416.x
更新日期:1996-12-01 00:00:00
abstract::Maxillary sinus floor augmentation with autogenous bone has become a widely accepted procedure in implant dentistry. The use of osteoconductive bone substitutes in this indication is controversial, since their use can lead to a prolonged healing time, inhomogenous ossification, foreign body reaction, migration of part...
journal_title:Clinical oral implants research
pub_type: 杂志文章
doi:10.1034/j.1600-0501.1999.100609.x
更新日期:1999-12-01 00:00:00
abstract:OBJECTIVE:To appraise whether adverse biological events following oral implant placement may be associated with perioperative use of non-steroidal anti-inflammatory drugs (NSAIDs). METHODS:All patients treated in a university faculty postgraduate dental clinic between 1979 and 2012 that had experienced a failing and s...
journal_title:Clinical oral implants research
pub_type: 杂志文章
doi:10.1111/clr.12493
更新日期:2016-02-01 00:00:00
abstract:OBJECTIVES:As biomaterial-induced modulation of mediators of the immune response may be a potential therapeutic approach to enhance wound healing events, the aim of this study was to delineate the effects of titanium surface modification on macrophage phenotype and function. MATERIAL AND METHODS:Rodent bone marrow-der...
journal_title:Clinical oral implants research
pub_type: 杂志文章
doi:10.1111/clr.13522
更新日期:2019-11-01 00:00:00
abstract::The study aimed to examine the relationship between the subgingival flora around implants and their periodontal parameters. Plaque samples from 561 implants (279 patients) were analyzed by means of differential phase contrast microscopy and compared with the sample site's probing depth, bleeding tendency on probing, a...
journal_title:Clinical oral implants research
pub_type: 杂志文章
doi:10.1034/j.1600-0501.1995.060401.x
更新日期:1995-12-01 00:00:00
abstract:PURPOSE:The aim of this study was to evaluate the success rate of chemically modified and conventional sandblasted acid-etched surface (SLA) titanium implants in irradiated oral squamous cell carcinoma patients. MATERIAL AND METHODS:Twenty patients with a mean age of 61.1 years were treated with dental implants after ...
journal_title:Clinical oral implants research
pub_type: 杂志文章,随机对照试验
doi:10.1111/j.1600-0501.2010.02050.x
更新日期:2011-05-01 00:00:00
abstract::The purpose of this study was to compare the clinical and microbiological (microscopic) parameters during the development of experimental gingivitis and experimental peri-implant mucositis. Twenty partially edentulous patients were treated for moderate to advanced periodontal disease. Following active periodontal ther...
journal_title:Clinical oral implants research
pub_type: 杂志文章
doi:10.1034/j.1600-0501.1994.050409.x
更新日期:1994-12-01 00:00:00
abstract:OBJECTIVES:The purpose of this in vitro study was to evaluate fracture loads of implant-supported zirconia-based prostheses fabricated with different veneer materials (resin-based material and lithium disilicate ceramics). MATERIAL AND METHODS:Forty-four zirconia-based molar prostheses were fabricated on dental implan...
journal_title:Clinical oral implants research
pub_type: 杂志文章
doi:10.1111/clr.13135
更新日期:2018-04-01 00:00:00
abstract:BACKGROUND:Alumina-toughened zirconia (ATZ) is a possible alternative material to titanium for oral implants. No data are available on the fracture strength of ATZ oral implants. PURPOSE:The purpose of this study was to examine one-piece implants made of ATZ ceramic under artificial loading conditions and to compare t...
journal_title:Clinical oral implants research
pub_type: 杂志文章
doi:10.1111/j.1600-0501.2010.01954.x
更新日期:2010-12-01 00:00:00
abstract:AIM:This study sought to investigate dimensional changes to the alveolar bone following extraction and application of novel devices used for obturation of socket orifice (socket cap) and space maintenance in sockets with facial dehiscence (socket cage). MATERIAL AND METHODS:Six Macaca fascicularis had six teeth each r...
journal_title:Clinical oral implants research
pub_type: 杂志文章
doi:10.1111/clr.12521
更新日期:2016-01-01 00:00:00
abstract:OBJECTIVES:The aim of this study was to investigate the outcomes of the installation of two implant-supported overdentures until such treatment is complete. Although this treatment is well established in the literature, there are no studies comparing what happens to muscles and the quality of life (QoL) of patients dur...
journal_title:Clinical oral implants research
pub_type: 杂志文章
doi:10.1111/clr.12980
更新日期:2017-10-01 00:00:00
abstract:OBJECTIVES:Protocols of immediate loading have been reported in several studies. It has also been demonstrated that the cause of failure of immediate loaded implants is due to the micromotion on the bone-implant interface induced by immediate loading. There should be a minimum gap between the implant and the peri-impla...
journal_title:Clinical oral implants research
pub_type: 杂志文章
doi:10.1111/j.1600-0501.2010.02036.x
更新日期:2011-05-01 00:00:00
abstract:OBJECTIVE:Graft consolidation follows a gradient that reflects the properties of bone substitutes at sites of sinus augmentation. Here we present an analytical method to investigate the process of graft consolidation taking the distance from the maxillary host bone into account. MATERIAL AND METHODS:We therefore evalu...
journal_title:Clinical oral implants research
pub_type: 杂志文章
doi:10.1111/j.1600-0501.2009.01733.x
更新日期:2009-10-01 00:00:00
abstract::The presence of certain glycosaminoglycans in peri-implant sulcus fluid may be an effective means of monitoring changes in bone metabolic activity following initial loading of implant abutments. This study has investigated levels of chondroitin 4 sulphate and hyaluronan in peri-implant sulcus fluid from titanium osseo...
journal_title:Clinical oral implants research
pub_type: 杂志文章
doi:10.1034/j.1600-0501.1991.020404.x
更新日期:1991-10-01 00:00:00
abstract:AIM:The aim of this study was to retrospectively analyze the potential influence of implant inclination on marginal bone loss at freestanding, implant-supported, fixed partial dentures (FPDs) over a 5-year period of functional loading. MATERIAL AND METHODS:The material comprised 38 periodontally treated, partially den...
journal_title:Clinical oral implants research
pub_type: 杂志文章
doi:10.1111/j.1600-0501.2007.01386.x
更新日期:2007-10-01 00:00:00
abstract:PURPOSE:The aim of this prospective study was to evaluate the soft tissue changes around implants in the aesthetic zone, placed under a trimodal approach (immediate post-extraction placement, flapless, and immediate provisional restoration) and its relationship to gingival/periodontal biotype of the patient. MATERIALS...
journal_title:Clinical oral implants research
pub_type: 杂志文章
doi:10.1111/j.1600-0501.2012.02516.x
更新日期:2013-10-01 00:00:00
abstract::Microbial plaque accumulation on titanium dental implant surfaces can result in an inflammatory condition of the surrounding tissues. Cleaning of such a contaminated surface, in vivo, by means of a solution of amino-alcohol, following surgical exposure, has been proposed. However, the tissue healing following treatmen...
journal_title:Clinical oral implants research
pub_type: 杂志文章
doi:10.1034/j.1600-0501.1999.100303.x
更新日期:1999-06-01 00:00:00
abstract::Four different surface modifications were designed. Forty screw-shaped implants were divided into 4 groups, 10 screws in each. Every screw was prepared with 2 different surface topographies. The surface topography was measured with a confocal laser scanning profilometer and the surface roughness was characterized usin...
journal_title:Clinical oral implants research
pub_type: 杂志文章
doi:10.1034/j.1600-0501.1998.090102.x
更新日期:1998-02-01 00:00:00
abstract:PURPOSE:To evaluate maximal occlusal bite forces (MOF) and marginal bone level (MBL) changes in patients with implant-tooth-supported fixed partial prostheses (FPP). MATERIAL AND METHODS:Twenty nine partially edentulous patients consecutively who received 34 three-occlusal unit FPP with terminal implant and tooth supp...
journal_title:Clinical oral implants research
pub_type: 杂志文章
doi:10.1111/j.1600-0501.2005.01169.x
更新日期:2006-06-01 00:00:00
abstract::A clinical and radiographical study was performed to evaluate the treatment outcome of single tooth replacements with artificial crowns retained to implants installed according to a 1-stage surgical procedure and immediate loading (Experimental Group = EG) in comparison to the original 2-stage concept (Control Group =...
journal_title:Clinical oral implants research
pub_type: 临床试验,杂志文章
doi:10.1034/j.1600-0501.2000.011001026.x
更新日期:2000-02-01 00:00:00
abstract::The aim of this study was to investigate whether a new connective tissue attachment can occur on a surface of hydroxyapatite (HA) when periodontal ligament (PDL)-derived cells with the ability to form new connective tissue attachment are allowed to populate the surface of HA. Six maxillary canines from 3 cats were use...
journal_title:Clinical oral implants research
pub_type: 杂志文章
doi:10.1034/j.1600-0501.1993.040303.x
更新日期:1993-09-01 00:00:00
abstract:OBJECTIVES:Data on posterior alveolar ridge resorption (PARR) in patients with two implant supported mandibular overdentures is very heterogeneous. The aim of this prospective study was to observe the PARR after ten years for a study population treated with a titanium bar retained overdenture on two IMZ-implants. MATE...
journal_title:Clinical oral implants research
pub_type: 临床试验,杂志文章
doi:10.1111/clr.12393
更新日期:2015-12-01 00:00:00
abstract:OBJECTIVE:The aim of this systematic review was to investigate the influence of bone mineral density on the primary stability of dental implants. MATERIAL AND METHODS:A search of health science databases (Cochrane Library, MEDLINE-PubMed, ISI Web of Knowledge, EMBASE, LILACS) and grey literature was performed, includi...
journal_title:Clinical oral implants research
pub_type: 杂志文章,评审
doi:10.1111/j.1600-0501.2011.02228.x
更新日期:2012-07-01 00:00:00
abstract:OBJECTIVE:The aim of this study was to determine the long-term outcome of implant insertion in the augmented severely atrophied maxilla. STUDY DESIGN:Three hundred and twenty-four implants were inserted in 35 patients (eight males, 27 females, average age 57.6 years) in extremely atrophied maxillae after osteotomy and...
journal_title:Clinical oral implants research
pub_type: 杂志文章
doi:10.1111/j.1600-0501.2004.01074.x
更新日期:2004-12-01 00:00:00
abstract:OBJECTIVES:The aim of the present publication was to report on the EAO Workshop group-4 discussions and consensus statements on the five reviews previously prepared. These reviews provided the scientific evidence on the effect of crown-to-implant ratio, on reconstructions with cantilevers in fully and partially edentul...
journal_title:Clinical oral implants research
pub_type: 共识发展会议,杂志文章
doi:10.1111/clr.13284
更新日期:2018-10-01 00:00:00