Safe and acceptable strategies for producing foreign molecules in plants.

Abstract:

:The ability to express foreign genes using transgenic technologies has opened up options for producing large quantities of commercially important industrial or pharmaceutical products in plants. These technologies have made it possible to use well-developed systems of commercial agriculture that were developed principally to produce raw material for large-scale food, feed or processing applications for the production of foreign molecules. The possibility of the novel industrial or pharmaceutical molecules produced in such plants, or components derived from them, contaminating the environment and food chains has become especially controversial. This potential contamination has prompted detailed consideration of how such crops and the molecules that they produce can be effectively isolated and contained. First, the crop can be completely isolated physically from its food or feed counterpart during every aspect of its development and commercialization. Second, genetic isolation systems or genetic barriers that prevent normal reproduction can be used to reduce the likelihood of the industrial or pharmaceutical crop entering the food chain.

journal_name

Curr Opin Plant Biol

authors

Mascia PN,Flavell RB

doi

10.1016/j.pbi.2004.01.014

subject

Has Abstract

pub_date

2004-04-01 00:00:00

pages

189-95

issue

2

eissn

1369-5266

issn

1879-0356

pii

S1369526604000172

journal_volume

7

pub_type

杂志文章,评审
  • Root border cells and secretions as critical elements in plant host defense.

    abstract::Border cells and border-like cells are released from the root tip as individual cells and small aggregates, or as a group of attached cells. These are viable components of the root system that play a key role in controlling root interaction with living microbes of the rhizosphere. As their separation from root tip pro...

    journal_title:Current opinion in plant biology

    pub_type: 杂志文章,评审

    doi:10.1016/j.pbi.2013.06.010

    authors: Driouich A,Follet-Gueye ML,Vicré-Gibouin M,Hawes M

    更新日期:2013-08-01 00:00:00

  • Environmental regulation of stomatal development.

    abstract::Stomata are microscopic structures in the epidermis of the aerial parts of flowering plants formed by two specialized guard cells flanking a central pore. The role of stomata is to optimize gas exchange (the uptake of carbon dioxide and the loss of water vapor) to suit the prevailing environmental conditions. To do th...

    journal_title:Current opinion in plant biology

    pub_type: 杂志文章,评审

    doi:10.1016/j.pbi.2009.08.005

    authors: Casson SA,Hetherington AM

    更新日期:2010-02-01 00:00:00

  • Non-linear signaling for pattern formation?

    abstract::Developmental pathways are often simplified as linear cascades of gene activation caused by initial signaling events. Recent data, however, support a more complex view in which non-linear responses to signals are important for pattern formation. First, a positive feedback loop may regulate cellular patterning in the A...

    journal_title:Current opinion in plant biology

    pub_type: 杂志文章,评审

    doi:10.1016/s1369-5266(00)00105-9

    authors: Scheres B

    更新日期:2000-10-01 00:00:00

  • Regulatory metabolic networks in drought stress responses.

    abstract::Plants must adapt to drought stress to survive. The phytohormone abscisic acid (ABA) is produced under drought stress conditions and is essential for the response to drought stress. The ABA level plays an important role in the response, and several enzymes for ABA biosynthesis and catabolism have been identified. Phys...

    journal_title:Current opinion in plant biology

    pub_type: 杂志文章,评审

    doi:10.1016/j.pbi.2007.04.014

    authors: Seki M,Umezawa T,Urano K,Shinozaki K

    更新日期:2007-06-01 00:00:00

  • Redox control of systemic acquired resistance.

    abstract::Changes in gene expression during systemic acquired resistance (SAR) require the phenolic signaling molecule salicylic acid (SA) and are modulated by the interaction between the NON EXPRESSOR OF PATHOGENESIS-RELATED GENES1 (NPR1) protein and members of the TGA family of transcription factors. In the past two years, th...

    journal_title:Current opinion in plant biology

    pub_type: 杂志文章,评审

    doi:10.1016/j.pbi.2005.05.003

    authors: Fobert PR,Després C

    更新日期:2005-08-01 00:00:00

  • Complex sexual signals for the male gametophyte.

    abstract::The pollen grain and the pollen tube that grows from it are complex entities which must respond to a diverse array of signals to carry out their roles in sexual reproduction. Research is beginning to reveal the nature both of the signals and of the signal transduction machinery that converts these signals into directi...

    journal_title:Current opinion in plant biology

    pub_type: 杂志文章,评审

    doi:10.1016/s1369-5266(99)00015-1

    authors: Pruitt RE

    更新日期:1999-10-01 00:00:00

  • Applied plant genomics: the secret is integration.

    abstract::Although concerted efforts to understand selected botanical models have been made, the resulting basic knowledge varies in its applicability to other diverse species including the major crops. Recent advances in high-throughput genomics are offering new avenues through which to exploit model systems for the study of b...

    journal_title:Current opinion in plant biology

    pub_type: 杂志文章,评审

    doi:10.1016/s1369-5266(02)00246-7

    authors: Osterlund MT,Paterson AH

    更新日期:2002-04-01 00:00:00

  • The evolutionary basis of leaf senescence: method to the madness?

    abstract::Recent studies on the differential expression of genes associated with leaf senescence support the long-standing interpretation of plant senescence as an organized, genetically controlled process. Sequence identities of genes that are differentially expressed in senescing leaves indicate roles in the salvage of nutrie...

    journal_title:Current opinion in plant biology

    pub_type: 杂志文章,评审

    doi:10.1016/s1369-5266(98)80131-3

    authors: Bleecker AB

    更新日期:1998-02-01 00:00:00

  • Cytokinin signaling.

    abstract::Although cytokinin plays a central role in plant development, our knowledge of the biosynthesis, distribution, perception and signal transduction of cytokinin is limited. Recent molecular-genetic studies have, however, implicated involvement of a two-component system in cytokinin signal transduction. Furthermore, new ...

    journal_title:Current opinion in plant biology

    pub_type: 杂志文章,评审

    doi:10.1016/s1369-5266(98)80263-x

    authors: Kakimoto T

    更新日期:1998-10-01 00:00:00

  • Calcium regulation of tip growth: new genes for old mechanisms.

    abstract::We review the recent advances on Ca(2+) in tip-growing cells, with a special focus on pollen tubes. New genes for Ca(2+) pumps, channels and sensing proteins have been recently described, with special emphasis on cyclic nucleotide gated channels (CNGCs) and glutamate receptor-like channels (GLRs). We also review the c...

    journal_title:Current opinion in plant biology

    pub_type: 杂志文章,评审

    doi:10.1016/j.pbi.2011.09.005

    authors: Konrad KR,Wudick MM,Feijó JA

    更新日期:2011-12-01 00:00:00

  • Current progress in the use of traditional medicines and nutraceuticals.

    abstract::Traditional medicines in the form of botanical dietary supplements and nutraceuticals have found a place in 21st century healthcare. They nonetheless all contain compounds that are foreign to humans (i.e. xenobiotics) and that are subject to the same pharmacological issues encountered by synthetic therapeutic agents. ...

    journal_title:Current opinion in plant biology

    pub_type: 杂志文章,评审

    doi:10.1016/j.pbi.2005.03.010

    authors: Barnes S,Prasain J

    更新日期:2005-06-01 00:00:00

  • Effector proteins that modulate plant--insect interactions.

    abstract::Insect herbivores have highly diverse life cycles and feeding behaviors. They establish close interactions with their plant hosts and suppress plant defenses. Chewing herbivores evoke characteristic defense responses distinguishable from general mechanical damage. In addition, piercing-sucking hemipteran insects displ...

    journal_title:Current opinion in plant biology

    pub_type: 杂志文章,评审

    doi:10.1016/j.pbi.2011.05.003

    authors: Hogenhout SA,Bos JI

    更新日期:2011-08-01 00:00:00

  • A matter of size: developmental control of organ size in plants.

    abstract::The intrinsic size of plant organs is determined by developmental signals, yet the molecular and genetic mechanisms that control organ size are largely unknown. Ongoing functional analysis of Arabidopsis genes is defining important regulators involved in these mechanisms. Key features of this control are the coordinat...

    journal_title:Current opinion in plant biology

    pub_type: 杂志文章,评审

    doi:10.1016/s1369-5266(00)00212-0

    authors: Mizukami Y

    更新日期:2001-12-01 00:00:00

  • Signaling in shoot and flower meristems of Arabidopsis thaliana.

    abstract::Meristems are centers of cell proliferation with a defined internal structure that is dynamically perpetuated throughout a plant's life although its constituent cells constantly change. When progressing from stem cell state towards differentiation, individual cells adopt developmental programs according to their curre...

    journal_title:Current opinion in plant biology

    pub_type: 杂志文章,评审

    doi:10.1016/j.pbi.2013.11.011

    authors: Holt AL,van Haperen JM,Groot EP,Laux T

    更新日期:2014-02-01 00:00:00

  • Strategies for improving C4 photosynthesis.

    abstract::Recent activities to improve photosynthetic performance in crop plants has focused mainly on C3 photosynthesis where there are clear identified targets such as improving Rubisco kinetics, installation of a CO2 concentrating mechanism and alleviating limitations in chloroplast electron transport. Here we address strate...

    journal_title:Current opinion in plant biology

    pub_type: 杂志文章,评审

    doi:10.1016/j.pbi.2016.04.003

    authors: von Caemmerer S,Furbank RT

    更新日期:2016-06-01 00:00:00

  • Filamentous pathogen effector functions: of pathogens, hosts and microbiomes.

    abstract::Microorganisms play essential roles in almost every environment on earth. For instance, microbes decompose organic material, or establish symbiotic relationships that range from pathogenic to mutualistic. Symbiotic relationships have been particularly well studied for microbial plant pathogens and have emphasized the ...

    journal_title:Current opinion in plant biology

    pub_type: 杂志文章,评审

    doi:10.1016/j.pbi.2014.05.001

    authors: Rovenich H,Boshoven JC,Thomma BP

    更新日期:2014-08-01 00:00:00

  • Phosphate scouting by root tips.

    abstract::Chemistry assigns phosphate (Pi) dominant roles in metabolism; however, it also renders the macronutrient a genuinely limiting factor of plant productivity. Pi bioavailability is restricted by low Pi mobility in soil and antagonized by metallic toxicities, which force roots to actively seek and selectively acquire the...

    journal_title:Current opinion in plant biology

    pub_type: 杂志文章,评审

    doi:10.1016/j.pbi.2017.04.016

    authors: Abel S

    更新日期:2017-10-01 00:00:00

  • ESCRT-dependent degradation of ubiquitylated plasma membrane proteins in plants.

    abstract::To control the abundance of plasma membrane receptors and transporters is crucial for proper perception and response to extracellular signals from surrounding cells and the environment. Posttranslational modification of plasma membrane proteins, especially ubiquitin conjugation or ubiquitylation, is key for the determ...

    journal_title:Current opinion in plant biology

    pub_type: 杂志文章,评审

    doi:10.1016/j.pbi.2017.07.003

    authors: Isono E,Kalinowska K

    更新日期:2017-12-01 00:00:00

  • The brassinosteroid signaling network-a paradigm of signal integration.

    abstract::Many hormonal and environmental signals regulate common cellular and developmental processes in plants. While the molecular pathways that transduce these signals have each been studied in detail, how these pathways are wired into regulatory networks to provide the coordinated responses has remained an outstanding ques...

    journal_title:Current opinion in plant biology

    pub_type: 杂志文章,评审

    doi:10.1016/j.pbi.2014.07.012

    authors: Wang W,Bai MY,Wang ZY

    更新日期:2014-10-01 00:00:00

  • Physcomitrella as a model system for plant cell biology and organelle-organelle communication.

    abstract::In multicellular eukaryotic cells, metabolism and growth are sustained by the cooperative functioning of organelles in combination with cell-to-cell communication at the organism level. In land plants, multiple strategies have evolved to adapt to life outside water. As basal land plant, the moss Physcomitrella patens ...

    journal_title:Current opinion in plant biology

    pub_type: 杂志文章,评审

    doi:10.1016/j.pbi.2019.05.007

    authors: Falz AL,Müller-Schüssele SJ

    更新日期:2019-12-01 00:00:00

  • Suberin--a biopolyester forming apoplastic plant interfaces.

    abstract::Suberized cell walls form physiologically important plant-environment interfaces because they act as barriers that limit water and nutrient transport and protect plants from invasion by pathogens. Plants respond to environmental stimuli by modifying the degree of suberization in root cell walls. Salt stress or drought...

    journal_title:Current opinion in plant biology

    pub_type: 杂志文章,评审

    doi:10.1016/j.pbi.2007.04.004

    authors: Franke R,Schreiber L

    更新日期:2007-06-01 00:00:00

  • Gibberellin signalling pathway.

    abstract::Recent molecular biological and genetical studies have identified several positive and negative regulators of gibberellin (GA) signalling pathways in higher plants. The DELLA protein functions as a negative regulator of GA signalling; its degradation through the ubiquitin/proteasome pathway is a key event in the regul...

    journal_title:Current opinion in plant biology

    pub_type: 杂志文章,评审

    doi:10.1016/s1369-5266(03)00079-7

    authors: Gomi K,Matsuoka M

    更新日期:2003-10-01 00:00:00

  • Proteomics approaches to understand protein phosphorylation in pathway modulation.

    abstract::Signaling pathways in all organisms consist of series of phosphorylation and dephosphorylation events that define directionality and allow different levels of feedback-regulation. Mass spectrometry-based proteomic analyses in recent years have led to a proteome-wide identification of thousands of phosphorylation sites...

    journal_title:Current opinion in plant biology

    pub_type: 杂志文章,评审

    doi:10.1016/j.pbi.2009.12.008

    authors: Schulze WX

    更新日期:2010-06-01 00:00:00

  • Protein farnesylation in plants--conserved mechanisms but different targets.

    abstract::Protein farnesylation has an important role in the regulation of plant development and signal transduction, but the exact function of this modification is not well understood. The identification of protein farnesyltransferase substrates, together with the genetic analysis of mutants that are deficient in protein farne...

    journal_title:Current opinion in plant biology

    pub_type: 杂志文章,评审

    doi:10.1016/j.pbi.2003.09.005

    authors: Galichet A,Gruissem W

    更新日期:2003-12-01 00:00:00

  • The way out and in: phloem loading and unloading of amino acids.

    abstract::Amino acids represent the major transport form of reduced nitrogen in plants. Long-distance transport of amino acids occurs in the xylem and the phloem. However, the phloem is the main transport route for bulk flow of the organic nitrogen from source leaves to sink tissues. Phloem loading in leaves of most annual plan...

    journal_title:Current opinion in plant biology

    pub_type: 杂志文章,评审

    doi:10.1016/j.pbi.2017.12.002

    authors: Tegeder M,Hammes UZ

    更新日期:2018-06-01 00:00:00

  • Lonely at the top? Regulation of shoot apical meristem activity by intrinsic and extrinsic factors.

    abstract::All the above-ground organs of a plant are derived from stem cells that reside in shoot apical meristems (SAM). Over the past 25 years, the genetic pathways that control the proliferation of stem cells within the SAM, and the differentiation of their progenitors into lateral organs, have been described in great detail...

    journal_title:Current opinion in plant biology

    pub_type: 杂志文章,评审

    doi:10.1016/j.pbi.2020.08.008

    authors: Fouracre JP,Poethig RS

    更新日期:2020-12-01 00:00:00

  • Volatiles as inducers and suppressors of plant defense and immunity-origins, specificity, perception and signaling.

    abstract::Volatiles from attacked plants, microbes and herbivores can enhance plant defenses. However, the absence of volatiles rather than their presence has sometimes been associated with enhanced defense, suggesting that volatiles may also act as defense suppressors. Recent work provides a potential mechanistic explanation f...

    journal_title:Current opinion in plant biology

    pub_type: 杂志文章,评审

    doi:10.1016/j.pbi.2018.03.008

    authors: Erb M

    更新日期:2018-08-01 00:00:00

  • Fungal pathogenicity.

    abstract::Successful penetration of living plant tissue by fungal pathogens is preceded by an exchange of signals between both organisms. Recent mutational approaches revealed the importance of cAMP-dependent signalling pathways for fungal development and virulence on their hosts. ...

    journal_title:Current opinion in plant biology

    pub_type: 杂志文章,评审

    doi:10.1016/1369-5266(88)80054-2

    authors: Knogge W

    更新日期:1998-08-01 00:00:00

  • Regulatory network of gene expression in the drought and cold stress responses.

    abstract::Molecular and genomic studies have shown that several genes with various functions are induced by drought and cold stresses, and that various transcription factors are involved in the regulation of stress-inducible genes. The products of stress-inducible genes function not only in stress tolerance but also in stress r...

    journal_title:Current opinion in plant biology

    pub_type: 杂志文章,评审

    doi:10.1016/s1369-5266(03)00092-x

    authors: Shinozaki K,Yamaguchi-Shinozaki K,Seki M

    更新日期:2003-10-01 00:00:00

  • Stressed genomics-bringing relief to rice fields.

    abstract::Active research in rice genetics aided by full-genome sequence has generated results to address multiple problems caused by biotic and abiotic stresses. The main challenges are achieving stability of resistance against variable biological agents and defining the genetic basis of traits influenced strongly by genotypex...

    journal_title:Current opinion in plant biology

    pub_type: 杂志文章,评审

    doi:10.1016/j.pbi.2007.12.005

    authors: Leung H

    更新日期:2008-04-01 00:00:00