Identification of four genomic loci highly related to casein-kinase-2-alpha cDNA and characterization of a casein kinase-2-alpha pseudogene within the mouse genome.

Abstract:

:Using the coding region of the human CK-2 alpha cDNA as a probe for screening a genomic mouse library, positive clones representing four different genomic loci were isolated. Partial DNA sequences of these loci encompassing the first 120 nucleotides of the putative coding region are reported. One positive clone was further analyzed by sequencing a 3.1 kb XbaI fragment. This clone displays the characteristics of a pseudogene, i.e. lack of introns and several nucleotide insertions and deletions. In its 3' region it contains a 91 bp large CT-rich stretch which consists of (CCTT) and (CT) repeats; in the 5' region three (CCCCCT) repeats.

authors

Boldyreff B,Wehr K,Hecht R,Issinger OG

doi

10.1016/0006-291x(92)90806-v

subject

Has Abstract

pub_date

1992-07-31 00:00:00

pages

723-30

issue

2

eissn

0006-291X

issn

1090-2104

pii

0006-291X(92)90806-V

journal_volume

186

pub_type

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