Enzyme activities of the mitochondrial energy generating system in skeletal muscle tissue of preterm and fullterm neonates.

abstract：BACKGROUND:Pregnancy represents a major risk factor for deep vein thrombosis (DVT). Most coagulation/fibrinolysis markers currently utilized change during pregnancy, and therefore they cannot accurately evaluate thrombotic events in pregnancy because the rate of false positive results is high. Fibrin monomer complex (F...

journal_title：Annals of clinical biochemistry

authors： Onishi H,Kaniyu K,Iwashita M,Tanaka A,Watanabe T

更新日期：2007-09-01 00:00:00

abstract：:The activity of serum deoxycytidylate deaminase, not hitherto reported to increase after myocardial infarction, has been investigated and the results have been related to other cardiac enzymes, including the MB fraction of creatine phosphokinase. Deoxycytidylate deaminase was found to increase to maximum activity on t...

journal_title：Annals of clinical biochemistry

authors： Roberts RG,Davies AG,Jones DD

更新日期：1978-11-01 00:00:00

abstract：:Erythrocuprein (superoxide dismutase) has recently been shown to have an enzymic function towards superoxide anions. The discovery of superoxide dismutase, its mode of action, and estimation are reviewed along with a brief introduction to oxygen activation and free-radical chemistry. The formation, activity, and destr...

journal_title：Annals of clinical biochemistry

authors： Gutteridge JM

更新日期：1976-05-01 00:00:00

abstract：:The most widely used methods for the assay of total bilirubin in serum are based on a coupling reaction with various diazo dyes in the presence of an accelerating agent. The 'direct' reaction, without accelerator, gives a good estimate of the conjugated and protein bound (delta) species of bilirubin only if carefully ...

journal_title：Annals of clinical biochemistry

authors： Westwood A

更新日期：1991-03-01 00:00:00

abstract：BACKGROUND:About 10 years ago, a survey showed significant deficiencies in the quality of gastrointestinal investigations performed by UK laboratories. Subsequently, several clinical guidelines have been developed and external quality assessment schemes introduced. This survey was performed to assess whether earlier de...

journal_title：Annals of clinical biochemistry

authors： Duncan A,Hill PG

更新日期：2007-03-01 00:00:00

abstract：:A case report is presented of a 37-year-old man who, largely by chance, was found to have a marked mixed hyperlipidaemia. As a teenager he had been treated for apparent idiopathic growth hormone deficiency, but had also never developed secondary sexual characteristics. Pituitary hormone measurement was now consistent ...

journal_title：Annals of clinical biochemistry

authors： Kilpatrick ES,Patmore JE,Rowland-Hill C,Atkin SL

更新日期：2004-07-01 00:00:00

abstract：BACKGROUND:Circulating levels of bioavailable oestradiol and testosterone are often desirable for clinical practice or investigational studies of children. However, assays to measure circulating hormone levels might not always be accessible. We sought to validate the empirical calculation of circulating bioavailable te...

journal_title：Annals of clinical biochemistry

authors： Egleston BL,Chandler DW,Dorgan JF

更新日期：2010-05-01 00:00:00

abstract：:This paper critically examines the usefulness of serum albumin measurement in the light of current laboratory practice and knowledge of the pathophysiology of albumin metabolism. The main conclusions and recommendations are as follows: (i) Albumin measurement forms a limited, but useful part of the investigation of li...

journal_title：Annals of clinical biochemistry

authors： Whicher J,Spence C

更新日期：1987-11-01 00:00:00

abstract：:The application of a DC plasma emission spectrometer to the measurement of copper, zinc and magnesium in serum and urine is reported. Each assay requires only a simple dilution in 1% nitric acid. Comparisons with standard atomic absorption techniques showed good analytical agreement, especially for copper and magnesiu...

journal_title：Annals of clinical biochemistry

authors： Roberts NB,Fairclough D,McLoughlin S,Taylor WH

更新日期：1985-09-01 00:00:00

abstract：BACKGROUND:We evaluated the recently released chemiluminescence assay for 25-hydroxy vitamin D (25-OHD) on the Immunodiagnostic Systems iSYS (IDS-iSYS) automated analyser. METHODS:The IDS-iSYS comparison was performed using patient samples previously measured for 25-OHD by a validated liquid chromatography-tandem mass...

journal_title：Annals of clinical biochemistry

authors： Cluse ZN,Fudge AN,Whiting MJ,McWhinney B,Parkinson I,O'Loughlin PD

更新日期：2012-03-01 00:00:00

abstract：BACKGROUND:It is important to explain target proteins for the understanding of the pathogenesis of vitreoretinal diseases. In a previous study, we identified more than 100 proteins including seven angiogenic-modulated factors in vitreous humours (VHs). Although there have been many reports of expressed protein profiles...

journal_title：Annals of clinical biochemistry

authors： Mukai N,Nakanishi T,Shimizu A,Takubo T,Ikeda T

更新日期：2008-05-01 00:00:00

abstract：:Seventeen laboratories in the British Isles participated in a study to compare six different commercially available immunoassays for serum lipoprotein(a) (Lp(a)) and to establish reasons for the variations in the measurement of serum Lp(a) concentrations. Pooled serum was distributed neat and after dilution at a centr...

journal_title：Annals of clinical biochemistry

authors： Mackness MI,Bhatnagar D,Weiringa G,MBewu A,Haynes B,Durrington PN

更新日期：1996-01-01 00:00:00

abstract：OBJECTIVE:The initial discovery of leptin (1994) has given rise to a substantial number of published studies. This study aimed at identifying the published data on the reference ranges of total, free and bound leptin concentration in the healthy prepubertal population. METHODS:A search was conducted on original Englis...

journal_title：Annals of clinical biochemistry

authors： Venner AA,Doyle-Baker PK,Lyon ME,Fung TS

更新日期：2009-01-01 00:00:00

abstract：:Plasma immunoreactive alpha-atrial natriuretic peptide (IR alpha-ANP) levels were determined before, and at 5 and 10 min after bolus intravenous administration of morphine (0.15 or 0.30 mg/kg) in 21 otherwise healthy human subjects who underwent elective surgery. Five min after injection IR alpha-ANP levels had nearly...

journal_title：Annals of clinical biochemistry

authors： Oğütman C,Ozben T,Sadan G,Trakya A,Isbir M

更新日期：1990-01-01 00:00:00

abstract：:Many techniques for the estimation of specific proteins measure light scattered by, or the turbidity of, suspensions of antigen:antibody aggregates formed in fluid-phase reactions. Although the shapes of reaction curves obtained are well documented, interpretation of the data in relation to the laws of light scatterin...

journal_title：Annals of clinical biochemistry

authors： Deverill I,Lock RJ

更新日期：1983-07-01 00:00:00

abstract：BACKGROUND:Individuals who are unable to metabolize the short-acting muscle relaxant succinylcholine due to abnormal cholinesterase activity are currently investigated via spectrophotometry using artificial substrates and enzyme inhibitors. Methods have been described using succinylcholine as substrate but with measure...

journal_title：Annals of clinical biochemistry

authors： Spencer JD,Rushton D,Allen KR

更新日期：2010-05-01 00:00:00

abstract：:Adequate control of performance in immunoassays of maternal serum alpha-fetoprotein is an essential part of screening for neural tube defects. Information derived from external quality assessment schemes may be of limited value in monitoring individual laboratory performance and stresses the need for proper internal q...

journal_title：Annals of clinical biochemistry

authors： Woodhead JS,Kemp HA,Nix AB,Rowlands RJ

更新日期：1980-11-01 00:00:00

abstract：:A comparative evaluation of Beckman (A), Boehringer (B), and Calbiochem (C) kits for the enzymatic end-point determination of urea has been carried out. Acceptable within-day and day-to-day precision was obtained with all kits. The recoveries obtained fulfilled the criteria of Logan (CRC Critical Reviews in Clinical L...

journal_title：Annals of clinical biochemistry

authors： Fraser CG,Fudge AN

更新日期：1978-09-01 00:00:00

abstract：:The fasting hyperinsulinaemia characteristic of obesity is due to pancreatic hypersecretion and is accompanied by a corresponding increase in plasma C-peptide concentrations. The exaggerated plasma insulin and C-peptide responses to oral glucose in obese subjects which is greater for insulin than C-peptide suggests th...

journal_title：Annals of clinical biochemistry

authors： Gama R,Marks V

更新日期：1989-09-01 00:00:00

abstract：:Auto-antibodies to oxidized low-density lipoprotein (ox-LDL) are thought to play a pivotal role in the pathogenesis of atherosclerosis. This study investigates the value of auto-antibodies to ox-LDL as a predictive marker of atherosclerosis in patients with both homozygous and heterozygous familial hypercholesterolaem...

journal_title：Annals of clinical biochemistry

authors： Paiker JE,Raal FJ,von Arb M

更新日期：2000-03-01 00:00:00

abstract：:A simultaneous deterioration in performance of several radioimmunoassays suggested that equipment was malfunctioning. Replicate counts from an automated gamma counter showed unacceptable variation during a 24-hour period; this variation was detected using Trigg's technique, a sensitive method for trend analysis, and w...

journal_title：Annals of clinical biochemistry

authors： Challand GS,Cox L

更新日期：1978-03-01 00:00:00

abstract：:Background Measured (MO) and calculated osmotic concentrations (CO) and the osmotic gap (OG) are commonly used in the investigation of electrolyte and volume disturbances as well as in cases of suspected volatile ingestion. Methods We compared 38 published formulae for CO with MO on a large data-set ( n = 9466) and ad...

journal_title：Annals of clinical biochemistry

authors： Wilgen U,Pretorius CJ,Ungerer JP

更新日期：2018-01-01 00:00:00

abstract：:Guaiac-based faecal occult blood tests (gFOBT) are still used in asymptomatic population bowel screening programmes but are being replaced by faecal immunochemical tests (FIT) for haemoglobin. gFOBT have many well-documented disadvantages and there is little evidence for their use in assessment of the symptomatic. Man...

journal_title：Annals of clinical biochemistry

authors： Fraser CG

更新日期：2012-11-01 00:00:00

abstract：:Mitochondrial acetoacetyl-CoA thiolase deficiency (or beta-ketothiolase deficiency) is a rare metabolic disorder characterized by acute episodes of severe acidosis and ketosis. A case is presented of an 18-month-old boy who presented with vomiting and diarrhoea and was found to be markedly acidotic. When the acidosis ...

journal_title：Annals of clinical biochemistry

authors： Tilbrook LK,Slater J,Agarwal A,Cyriac J

更新日期：2008-09-01 00:00:00

abstract：:We compared the diagnostic utility of recently proposed slope assays for serum creatine kinase and creatine kinase-2 with the optimized decision threshold assays. The former approach has been claimed to be superior to any other single diagnostic technique. We show, by ROC curve and likelihood ratio analyses, that the ...

journal_title：Annals of clinical biochemistry

authors： Leung FY,Griffith AP,Jablonsky G,Henderson AR

更新日期：1991-01-01 00:00:00

abstract：:Serum concentrations of total thyroid hormones, thyroid hormone binding proteins, free thyroid hormones and thyroid stimulating hormone (TSH) were measured in a large group of healthy normal subjects (n = 218) to determine the influence of age and sex on tests of thyroid function. No effect of age on measurements of t...

journal_title：Annals of clinical biochemistry

authors： Franklyn JA,Ramsden DB,Sheppard MC

更新日期：1985-09-01 00:00:00

abstract：BACKGROUND:Current practice requires regular venous blood samples for monitoring of tacrolimus concentrations post renal transplant requiring regular hospital visits. Mitra devices use volumetric absorptive microsampling technology and absorb a fixed amount of blood (10 μL) from a capillary blood sample. They are a via...

journal_title：Annals of clinical biochemistry

authors： Marshall DJ,Kim JJ,Brand S,Bryne C,Keevil BG

更新日期：2020-09-01 00:00:00

abstract：BACKGROUND:It is now established that the bioactive lipid lysophosphatidic acid (LPA) contributes to cancer initiation, progression and metastasis, including those of prostate cancer. LPA is produced in the serum and plasma mainly by conversion from lysophospholipids through the action of lysophospholipase D (lysoPLD),...

journal_title：Annals of clinical biochemistry

authors： Nakamura K,Takeuchi T,Ohkawa R,Okubo S,Yokota H,Tozuka M,Aoki J,Arai H,Ikeda H,Ohshima N,Kitamura T,Yatomi Y

更新日期：2007-11-01 00:00:00

abstract：BACKGROUND:The worldwide epidemic of obesity is a major public health concern and is persuasively linked to the rising prevalence of diabetes and cardiovascular disease. Obesity is often associated with an abnormal lipoprotein profile, which may be partly negated by pioglitazone intervention, as this can influence the ...

journal_title：Annals of clinical biochemistry

authors： McEneny J,McPherson PA,McGinty A,Hull SS,McCance DR,Young IS

更新日期：2013-01-01 00:00:00

abstract：:The effect of ambient temperature on the analytical and clinical performance of a glucose meter was examined. A total of 114 venous whole blood samples were analysed for glucose by a reference method, and by a glucose meter at 21-22 degrees C, room temperatures, 26-27 degrees C and 33-34 degrees C. Glucose meter readi...

journal_title：Annals of clinical biochemistry

authors： Nawawi H,Sazali BS,Kamaruzaman BH,Yazid TN,Jemain AA,Ismail F,Khalid BA

更新日期：2001-11-01 00:00:00