Abstract:
:The radiological findings in paediatric Gaucher disease (GD) are reviewed and future challenges for radiology are discussed. This overview is based on a literature review and our experience of children with GD in one of two national institutions for paediatric GD in the UK. GD is known to progress more rapidly in childhood. Current imaging is mainly suitable for ascertaining the complications of GD. The UK recommendations for routine radiological surveillance are discussed. With enzyme replacement therapy (ERT), which dramatically modifies the course of the disorder, the challenge for radiology in the future is likely to be assessing treatment efficacy rather than the detection of disease complications. Disease manifestations are likely to change in those on ERT and the most notable recent alteration in the disease profile in childhood is the virtual disappearance of the acute bone crisis in this population.
journal_name
Clin Radioljournal_title
Clinical radiologyauthors
McHugh K,Olsen E ØE,Vellodi Adoi
10.1016/j.crad.2003.09.010subject
Has Abstractpub_date
2004-02-01 00:00:00pages
117-23issue
2eissn
0009-9260issn
1365-229Xpii
S0009926003004197journal_volume
59pub_type
杂志文章,评审abstract::Computed tomographic (CT) findings in two cases of hepatic oil embolism following lymphangiography are described. Both patients had lymphatic obstruction and opacification of the liver due to collateral flow of lymphangiographic contrast. Computed tomography of the liver showed a distinctive branching pattern due to t...
journal_title:Clinical radiology
pub_type: 杂志文章
doi:10.1016/s0009-9260(89)80189-8
更新日期:1989-05-01 00:00:00
abstract::Skeletal radiological surveys in 161 renal transplant recipients identified 36 patients with 115 lesions of osteonecrosis. A further two patients with osteonecrosis found at autopsy had had no radiographic abnormality. The total incidence of osteonecrosis was, therefore, 38 (24%) out of 161. The lesions were frequentl...
journal_title:Clinical radiology
pub_type: 杂志文章
doi:10.1016/s0009-9260(85)80012-x
更新日期:1985-01-01 00:00:00
abstract:AIM:To investigate the imaging features of chondrosarcoma of the temporomandibular joint (TMJ) and review the literature. MATERIALS AND METHODS:Computed tomography (CT), magnetic resonance imaging (MRI), and integrated positron-emission tomography (PET)/CT images of nine patients with histopathologically confirmed cho...
journal_title:Clinical radiology
pub_type: 杂志文章
doi:10.1016/j.crad.2020.07.016
更新日期:2020-11-01 00:00:00
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journal_title:Clinical radiology
pub_type: 杂志文章
doi:10.1016/s0009-9260(85)80086-6
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abstract:AIM:To compare the accuracy of ultrasound and two magnetic resonance (MR) angiographic techniques with catheter angiography in assessing atherosclerosis at the carotid bifurcation. MATERIALS AND METHODS:Forty patients with symptomatic carotid stenosis were studied by Doppler ultrasound, time-of-flight MR angiography, ...
journal_title:Clinical radiology
pub_type: 临床试验,杂志文章
doi:10.1053/crad.2000.0518
更新日期:2000-12-01 00:00:00
abstract::A review of imaging in the acquired immune deficiency syndrome (AIDS) is presented. The imaging features can be conveniently categorized according to whether the presenting complications are infective (bacterial, protozoal, or fungal), bronchiectasis, neoplastic (Kaposi's sarcoma, AIDS-related lymphoma, or lymphoproli...
journal_title:Clinical radiology
pub_type: 杂志文章,评审
doi:10.1016/s0009-9260(98)80146-3
更新日期:1998-08-01 00:00:00
abstract:AIM:To develop and evaluate a radiomics composite model for predicting disease-free survival (DFS) in stage I solid lung adenocarcinoma, and compare it to a simple radiomics model. MATERIALS AND METHODS:Patients of pathological stage I solid lung adenocarcinoma treated with lobectomy (n = 119) were enrolled retrospect...
journal_title:Clinical radiology
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doi:10.1016/j.crad.2020.03.019
更新日期:2020-07-01 00:00:00
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journal_title:Clinical radiology
pub_type: 杂志文章
doi:10.1016/s0009-9260(82)80380-2
更新日期:1982-11-01 00:00:00
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journal_title:Clinical radiology
pub_type: 杂志文章
doi:10.1016/s0009-9260(98)80123-2
更新日期:1998-04-01 00:00:00
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journal_title:Clinical radiology
pub_type: 杂志文章,评审
doi:10.1016/j.crad.2015.06.093
更新日期:2015-11-01 00:00:00
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journal_title:Clinical radiology
pub_type: 杂志文章
doi:10.1016/j.crad.2013.10.003
更新日期:2014-02-01 00:00:00
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journal_title:Clinical radiology
pub_type: 杂志文章
doi:10.1016/s0009-9260(05)80373-3
更新日期:1992-11-01 00:00:00
abstract::111Indium (111In) WBC scintigraphy is an accurate method of assessing the extent of inflammatory bowel disease. A prospective study was performed to determine the correlation of ultrasound scanning with 111In WBC scintigraphy in the assessment of inflammatory bowel disease. Eighty-three indium and ultrasound scans wer...
journal_title:Clinical radiology
pub_type: 临床试验,杂志文章
doi:10.1016/s0009-9260(05)80896-7
更新日期:1990-12-01 00:00:00
abstract::Implant rupture is a common late complication of breast implant procedures. Ruptures are often silent and difficult to diagnose clinically. This review demonstrates normal appearances and sonographic signs of implant rupture. Breast sonologists should be aware of these signs and pitfalls in interpretation when imaging...
journal_title:Clinical radiology
pub_type: 杂志文章,评审
doi:10.1016/j.crad.2013.03.014
更新日期:2013-08-01 00:00:00
abstract::Magnetic resonance imaging (MRI) is the most accurate method of defining the morphology and haemodynamic features of thoracic aortic dissection. However, because of doubts about its safety in acute situations, its use has so far been confined to imaging chronic dissections. We present a prospective study of 50 patient...
journal_title:Clinical radiology
pub_type: 杂志文章
doi:10.1016/s0009-9260(05)83160-5
更新日期:1995-07-01 00:00:00
abstract::Cytomegalovirus (CMV) is the most commonly transmitted virus in utero with a prevalence of up to 1.5%. The infection has potentially debilitating and devastating consequences for the infected fetus, being a leading cause for neurological disability worldwide. Once acquired, it often goes undetected with only an assume...
journal_title:Clinical radiology
pub_type: 杂志文章,评审
doi:10.1016/j.crad.2020.02.009
更新日期:2020-08-01 00:00:00
abstract::Injury to the renal artery following blunt trauma is detected increasingly due to widespread and early use of multidetector computed tomography (CT), but optimal treatment remains controversial as no guidelines are available. This review illustrates the spectrum of imaging findings of traumatic renal artery dissection...
journal_title:Clinical radiology
pub_type: 杂志文章,评审
doi:10.1016/j.crad.2020.08.029
更新日期:2021-02-01 00:00:00
abstract:AIM:To investigate the clinical value of diffusion tensor imaging (DTI) in assessing renal function changes in diabetic patients with early-stage chronic kidney disease (CKD), and the relationship of DTI parameters with estimated glomerular filtration rate (eGFR) and urinary biomarkers. MATERIALS AND METHODS:Thirty-si...
journal_title:Clinical radiology
pub_type: 杂志文章
doi:10.1016/j.crad.2018.09.011
更新日期:2019-02-01 00:00:00
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journal_title:Clinical radiology
pub_type: 杂志文章,评审
doi:10.1016/j.crad.2010.09.006
更新日期:2011-02-01 00:00:00
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journal_title:Clinical radiology
pub_type: 杂志文章,评审
doi:10.1016/s0009-9260(98)80213-4
更新日期:1998-12-01 00:00:00
abstract::The lymphatic system of the abdomen comprises of the cisterna chyli, its major and minor lymphatic tributaries, and lymph nodes. Disorders of the lymphatic system of the abdomen are rarely encountered and consist of primary and secondary types. Abdominal lymphangiomas constitute the majority and have characteristic im...
journal_title:Clinical radiology
pub_type: 杂志文章,评审
doi:10.1016/j.crad.2016.06.116
更新日期:2016-10-01 00:00:00
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journal_title:Clinical radiology
pub_type: 杂志文章,评审
doi:10.1016/j.crad.2008.08.003
更新日期:2009-02-01 00:00:00
abstract::Non-tuberculous psoas abscess is associated with a wide variety of conditions in addition to its well known association with infection in the lumbar spine. Computed tomography (CT) enables the diagnosis to be made at a relatively early stage when classical physical signs may be absent. Percutaneous drainage under CT c...
journal_title:Clinical radiology
pub_type: 杂志文章
doi:10.1016/s0009-9260(86)80330-0
更新日期:1986-05-01 00:00:00
abstract::The Lesch-Nyhan syndrome is an x-linked defect of purine metabolism resulting in its classical form in major neurodevelopmental abnormality, hyperuricaemia, and hyperuricosuria. Uric acid calculi and crystalluria are common. Allopurinol is the main method of reducing serum and urinary uric acid levels, but results in ...
journal_title:Clinical radiology
pub_type: 杂志文章
doi:10.1016/s0009-9260(05)80352-6
更新日期:1991-01-01 00:00:00
abstract::Thirty-eight patients with an advanced ovarian cancer (FIGO stage III and IV) were randomly allocated to treatment, either with melphalan (M) or a combination of adriamycin, 5-fluorouracil and cyclophosphamide (CAF) to determine the effect on survival. Actuarial survival of the two treatment groups was the same but th...
journal_title:Clinical radiology
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1016/s0009-9260(82)80049-4
更新日期:1982-03-01 00:00:00
abstract::Systemic lupus erythematosus (SLE) is a well recognized cause of an acute abdomen. What is less well recognized is that the underlying pathology can be varied. The computed tomography (CT) and ultrasound appearances of the gall-bladder in a case of SLE serositis are shown. The imaging findings were strongly suggestive...
journal_title:Clinical radiology
pub_type: 杂志文章
doi:10.1016/s0009-9260(05)80670-1
更新日期:1991-12-01 00:00:00
abstract:AIMS:To investigate the clinical spectrum, cardiovascular magnetic resonance imaging (cMRI) characteristics, including T1 and extracellular volume fraction, and outcomes of Danon disease to facilitate further understanding of the phenotype of patients with Danon disease. MATERIALS AND METHODS:The study comprised six m...
journal_title:Clinical radiology
pub_type: 杂志文章
doi:10.1016/j.crad.2020.04.012
更新日期:2020-09-01 00:00:00
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journal_title:Clinical radiology
pub_type: 杂志文章
doi:10.1016/s0009-9260(05)81832-x
更新日期:1994-06-01 00:00:00
abstract::Iocetamic acid (Cholebrin) and calcium ipodate (Solubiloptin) were randomly allocated to two groups of 50 patients. Each patient completed a detailed questionnaire for side effects. There was no significant difference between the contrast media in their ability to opacify the gallbladder. Cholebrin was superior to Sol...
journal_title:Clinical radiology
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1016/s0009-9260(78)80046-4
更新日期:1978-09-01 00:00:00
abstract:AIM:To investigate the diagnostic ability of maximum standardised uptake value (SUVmax) at combined single-photon-emission computed tomography/computed tomography (SPECT/CT) for the evaluation of osteonecrosis of the jaw. MATERIALS AND METHODS:Seven patients with mandibular osteonecrosis (three osteoradionecrosis, thr...
journal_title:Clinical radiology
pub_type: 杂志文章
doi:10.1016/j.crad.2019.05.025
更新日期:2020-01-01 00:00:00