Abstract：
:The long-term effects on cardiovascular disease risk factors of a reduced fat (RF), ad libitum diet were compared with usual diet (control, CD) in glucose intolerance individuals. Participants were 136 adults aged > or =40 years with 'glucose intolerance' (2h blood glucose 7-11.0 mmol/l) detected at a Diabetes Survey who completed at 1 year intervention study of reduced fat, ad libitum diet versus usual diet. They were re-assessed at 2, 3 and 5 years. Main outcome measures were blood pressure, serum concentrations of total cholesterol, HDL and LDL cholesterol, total cholesterol:HDL ratio, triglycerides and body weight. The reduced fat diet lowered total cholesterol (P<0.01), LDL cholesterol (P< or =0.05), total cholesterol:HDL ratio (P< or =0.05), body weight (P<0.01) and systolic blood pressure (P< or =0.05) initially and diastolic blood pressure (P<0.01) long-term. No significant changes occurred in HDL cholesterol or triglycerides. In the more compliant 50% of the intervention group, systolic and diastolic blood pressure levels and body weight were lower at 1, 2 and 3 years (P<0.05). It was concluded that a reduced fat ad libitum diet has short-term benefits for cholesterol, body weight and systolic blood pressure and long-term benefits for diastolic blood pressure without significantly effecting HDL cholesterol and triglycerides despite participants regaining their lost weight.
journal_name
Diabetes Res Clin Practjournal_title
Diabetes research and clinical practiceauthors
Ley SJ,Metcalf PA,Scragg RK,Swinburn BAdoi
10.1016/j.diabres.2003.09.001subject
Has Abstractpub_date
2004-02-01 00:00:00pages
103-12issue
2eissn
0168-8227issn
1872-8227pii
S0168822703002183journal_volume
63pub_type
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journal_title：Diabetes research and clinical practice
pub_type： 杂志文章,多中心研究
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journal_title：Diabetes research and clinical practice
pub_type： 杂志文章,meta分析
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journal_title：Diabetes research and clinical practice
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journal_title：Diabetes research and clinical practice
pub_type： 临床试验,杂志文章,多中心研究,随机对照试验
doi：10.1016/j.diabres.2004.09.020
更新日期：2005-05-01 00:00:00
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journal_title：Diabetes research and clinical practice
pub_type： 杂志文章,多中心研究
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journal_title：Diabetes research and clinical practice
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journal_title：Diabetes research and clinical practice
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journal_title：Diabetes research and clinical practice
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journal_title：Diabetes research and clinical practice
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journal_title：Diabetes research and clinical practice
pub_type： 杂志文章,多中心研究
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更新日期：2011-12-01 00:00:00
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journal_title：Diabetes research and clinical practice
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journal_title：Diabetes research and clinical practice
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journal_title：Diabetes research and clinical practice
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pub_type： 杂志文章
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更新日期：2018-08-01 00:00:00
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journal_title：Diabetes research and clinical practice
pub_type： 杂志文章,评审
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更新日期：1998-04-01 00:00:00
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journal_title：Diabetes research and clinical practice
pub_type： 杂志文章
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更新日期：2000-12-01 00:00:00
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journal_title：Diabetes research and clinical practice
pub_type： 杂志文章
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更新日期：2020-12-08 00:00:00
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journal_title：Diabetes research and clinical practice
pub_type： 杂志文章,随机对照试验
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更新日期：2015-06-01 00:00:00
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journal_title：Diabetes research and clinical practice
pub_type： 杂志文章,评审
doi：10.1016/j.diabres.2018.04.036
更新日期：2018-09-01 00:00:00
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journal_title：Diabetes research and clinical practice
pub_type： 杂志文章
doi：10.1016/j.diabres.2016.01.029
更新日期：2016-05-01 00:00:00
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journal_title：Diabetes research and clinical practice
pub_type： 杂志文章
doi：10.1016/j.diabres.2004.03.007
更新日期：2004-11-01 00:00:00
