Effect of medical conditions on improvement in self-reported and observed functional performance of elders.

Abstract:

OBJECTIVES:To evaluate the effect of nine disabling medical conditions upon recovery from functional limitations by elders. DESIGN:Retrospective analysis of prospective longitudinal cohort. SETTING:Community. PARTICIPANTS:Persons aged 65 and older in Framingham Heart Study. MEASUREMENTS:Change in function in elders from biennial Examinations 18 (1983-85; baseline) through 23 (1994-96). At each examination, subjects reported limitations in heavy household work, walking up and down stairs, walking half a mile, bathing, toileting, and continence. They were also directly observed for performance of transferring in and out of a chair, dressing, walking 50 feet, and carrying a 10-pound object 10 feet. The prevalence of functional limitations and the incidence of recovery from functional limitation by the subsequent examination for each task were calculated. The effects of congestive heart failure, cognitive impairment, diabetes mellitus, stroke, depressive symptoms, hip fracture, knee pain, claudication, and chronic obstructive pulmonary disease were evaluated. The relationship between the total number of comorbid conditions present (0, 1, 2, 3 or more), the presence of each individual condition at the start of each examination cycle, and the incidence of recovery from functional limitations were examined using generalized estimating equations. RESULTS:One thousand eight hundred twenty-five subjects were studied at baseline; 1,026 were available 10 years later. Mean age of subjects at baseline was 73.5 (range 61-95); 60.7% were women. The prevalence of functional limitations ranged from 3.1% to 29.8% at biennial Examination 18 and increased to 15.1% to 32.4% at Examination 23. The incidence of recovery ranged from 3.2% to 78.4% depending upon the task and the examination cycle. Increasing disease burden, as measured by the number of comorbidities, was associated with a decreased likelihood of recovery from functional limitations. Diabetes mellitus, stroke, depressive symptoms, hip fracture, and knee pain had the strongest adverse effect upon recovery from functional limitations. CONCLUSION:In these community-dwelling elders, recovery from prevalent functional limitations was frequent. Increasing disease burden was associated with a decreased incidence of recovery. Diabetes mellitus, stroke, depressive symptoms, hip fracture, and knee pain had the strongest adverse effect on recovery from functional limitations.

journal_name

J Am Geriatr Soc

authors

Miller RR,Zhang Y,Silliman RA,Hayes MK,Leveille SG,Murabito JM,Kiel D,O'Connor GT,Felson DT

doi

10.1046/j.0002-8614.2004.52057.x

subject

Has Abstract

pub_date

2004-02-01 00:00:00

pages

217-23

issue

2

eissn

0002-8614

issn

1532-5415

pii

52057

journal_volume

52

pub_type

杂志文章
  • Replacement of Urinary Catheter for Urinary Tract Infections: A Prospective Observational Study.

    abstract:OBJECTIVES:To assess whether catheter replacement is associated with better clinical outcomes in individuals with long-term urinary catheters. DESIGN:Prospective, noninterventional study. PARTICIPANTS:Individuals (mean age 79.2±11.5) who had had an indwelling urinary catheter for longer than 7 days and a symptomatic ...

    journal_title:Journal of the American Geriatrics Society

    pub_type: 杂志文章

    doi:10.1111/jgs.15517

    authors: Babich T,Zusman O,Elbaz M,Ben-Zvi H,Paul M,Leibovici L,Avni T

    更新日期:2018-09-01 00:00:00

  • Use of the physician orders for life-sustaining treatment program in the clinical setting: a systematic review of the literature.

    abstract::The Physician Orders for Life-Sustaining Treatment (POLST) form is a palliative care tool that contains standardized, actionable medical orders. It is designed to ensure that patient treatment preferences are elicited, communicated, and honored throughout the healthcare system. A systematic review of the literature wa...

    journal_title:Journal of the American Geriatrics Society

    pub_type: 杂志文章,评审

    doi:10.1111/jgs.13248

    authors: Hickman SE,Keevern E,Hammes BJ

    更新日期:2015-02-01 00:00:00

  • Patterns of change in depression after stroke.

    abstract:OBJECTIVES:To provide estimates of change in depressive symptoms and determine how changes in depressive symptom influence recovery of functional status. DESIGN:Prospective cohort study. SETTING:Eleven inpatient medical rehabilitation facilities located across the United States. PARTICIPANTS:Five hundred forty-four ...

    journal_title:Journal of the American Geriatrics Society

    pub_type: 杂志文章,多中心研究

    doi:10.1111/j.1532-5415.2010.03266.x

    authors: Ostir GV,Berges IM,Ottenbacher A,Ottenbacher KJ

    更新日期:2011-02-01 00:00:00

  • Mild cognitive impairment is associated with poorer decision-making in community-based older persons.

    abstract:OBJECTIVE:To test the hypothesis that mild cognitive impairment (MCI) is associated with poorer financial and healthcare decision-making. DESIGN:Community-based epidemiological cohort study. SETTING:Communities throughout northeastern Illinois. PARTICIPANTS:Older persons without dementia from the Rush Memory and Agi...

    journal_title:Journal of the American Geriatrics Society

    pub_type: 杂志文章

    doi:10.1111/jgs.13346

    authors: Han SD,Boyle PA,James BD,Yu L,Bennett DA

    更新日期:2015-04-01 00:00:00

  • Home automated external defibrillators in a geriatric population: a brief discussion of the evidence.

    abstract::The literature has identified significant successes in cardiac resuscitation with the use of automated external defibrillators (AEDs) in public areas. As of September 2004, the Food and Drug Administration has authorized the purchase of these devices by the general public without a prescription. For the practicing ger...

    journal_title:Journal of the American Geriatrics Society

    pub_type: 杂志文章,评审

    doi:10.1111/j.1532-5415.2005.00569.x

    authors: Peery CA,Galanos AN

    更新日期:2006-01-01 00:00:00

  • Patient-related predictors of rehabilitation use for community-dwelling older Americans.

    abstract:OBJECTIVE:To determine patient factors that predict use of physical or occupational therapy (PT/OT) services by elderly people. DESIGN:Time-series study of the relationship of PT/OT use to a variety of characteristics present at baseline. PARTICIPANTS:Eight-hundred nine community-dwelling men and women aged 65 and ol...

    journal_title:Journal of the American Geriatrics Society

    pub_type: 杂志文章

    doi:10.1111/j.1532-5415.1992.tb02131.x

    authors: Mayer-Oakes SA,Hoenig H,Atchison KA,Lubben JE,De Jong F,Schweitzer SO

    更新日期:1992-04-01 00:00:00

  • Troublesome and disruptive behaviors in dementia. Relationships to diagnosis and disease severity.

    abstract::Patients with dementia often manifest troublesome and disruptive behaviors in addition to intellectual impairments. This study evaluated behavioral disturbances in 126 demented patients examined sequentially, using questionnaires administered to primary caregivers to quantify the types and severity of behavioral distu...

    journal_title:Journal of the American Geriatrics Society

    pub_type: 杂志文章

    doi:10.1111/j.1532-5415.1988.tb04260.x

    authors: Swearer JM,Drachman DA,O'Donnell BF,Mitchell AL

    更新日期:1988-09-01 00:00:00

  • Predicting intellectual level from the Mini-Mental State Examination.

    abstract::The Mini-Mental State Examination and the WAIS-R were administered to 105 patients in the early stages of Alzheimer's disease. MMSE scores correlated 0.83 with full scale IQ, which indicates that the MMSE may be a reasonable alternative measure of overall intellectual functioning in Alzheimer patients, for whom more e...

    journal_title:Journal of the American Geriatrics Society

    pub_type: 杂志文章

    doi:10.1111/j.1532-5415.1988.tb04020.x

    authors: Farber JF,Schmitt FA,Logue PE

    更新日期:1988-06-01 00:00:00

  • Attitudes toward self-determined death: a survey of primary care physicians.

    abstract:OBJECTIVE:To survey physicians to determine whether sociodemographic and practice-related variables are predictive of their attitudes toward suicide. DESIGN:Mailed questionnnaire survey. SETTING:Monroe County, New York. PARTICIPANTS:A 50 percent random sample of practicing primary care physicians. Of 186 potential r...

    journal_title:Journal of the American Geriatrics Society

    pub_type: 杂志文章

    doi:10.1111/j.1532-5415.1995.tb05814.x

    authors: Duberstein PR,Conwell Y,Cox C,Podgorski CA,Glazer RS,Caine ED

    更新日期:1995-04-01 00:00:00

  • High arterial pulse wave velocity is a risk factor for falls in community-dwelling older people.

    abstract:OBJECTIVES:To examine whether arterial stiffness is a risk factor for falls in community-dwelling older people. DESIGN:Prospective cohort study. SETTING:Community population, Sydney, Australia. PARTICIPANTS:Community-dwelling older adults (mean age 79.8±4.4, 52.2% female; N=481). MEASUREMENTS:Carotid-femoral pulse ...

    journal_title:Journal of the American Geriatrics Society

    pub_type: 杂志文章

    doi:10.1111/jgs.12931

    authors: Wong AK,Lord SR,Trollor JN,Sturnieks DL,Delbaere K,Menant J,Brodaty H,Sachdev PS,Close JC

    更新日期:2014-08-01 00:00:00

  • Gender differences in the behavioral manifestations of Alzheimer's disease.

    abstract:OBJECTIVE:To examine the relationship between gender and specific types of behavior problems that occur in patients with Alzheimer's disease. DESIGN:This was an observational study using the Dementia Behavior Disturbance Scale to quantify and define behavioral problems encountered by caregivers. Multiple regressions w...

    journal_title:Journal of the American Geriatrics Society

    pub_type: 杂志文章

    doi:10.1111/j.1532-5415.1996.tb01447.x

    authors: Ott BR,Tate CA,Gordon NM,Heindel WC

    更新日期:1996-05-01 00:00:00

  • Understanding the reasons for the underuse of pneumococcal vaccination by community-dwelling older African Americans.

    abstract:OBJECTIVES:To understand the potential roles of various patient and provider factors in the underuse of pneumococcal vaccination in Medicare-eligible older African Americans. DESIGN:The Cardiovascular Health Study. SETTING:Four U.S. states. PARTICIPANTS:Seven hundred ninety-five pairs of community-dwelling Medicare-...

    journal_title:Journal of the American Geriatrics Society

    pub_type: 杂志文章,多中心研究

    doi:10.1111/j.1532-5415.2010.03181.x

    authors: Jones LG,Zhang Y,Ahmed MI,Ekundayo OJ,Akhter S,Sawyer P,Aban I,Sims RV,Ahmed A

    更新日期:2010-12-01 00:00:00

  • Effect of individualized social activity on sleep in nursing home residents with dementia.

    abstract:OBJECTIVES:To test the efficacy of an individualized social activity intervention (ISAI) on decreasing daytime sleep, improving nighttime sleep, and lowering the day/night sleep ratio and to determine its cost. DESIGN:Pretest/posttest randomized with an experimental and control group. SETTING:Seven nursing homes. PA...

    journal_title:Journal of the American Geriatrics Society

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1111/j.1532-5415.2005.53460.x

    authors: Richards KC,Beck C,O'Sullivan PS,Shue VM

    更新日期:2005-09-01 00:00:00

  • Severe impairment of dietary folate utilization in the elderly.

    abstract::Absorption of folates, vitamin B6, pantothenate, and riboflavin from a natural food source (yeast) and from synthetic folylmonoglutamate was studied in 24 elderly subjects (age range, 73 to 101 years) and in 12 healthy younger subjects (age range, 24 to 42 years). All subjects absorbed riboflavin, vitamin B6, and pant...

    journal_title:Journal of the American Geriatrics Society

    pub_type: 杂志文章

    doi:10.1111/j.1532-5415.1978.tb01962.x

    authors: Baker H,Jaslow SP,Frank O

    更新日期:1978-05-01 00:00:00

  • Prevalence and correlates of recognized depression in U.S. nursing homes.

    abstract:OBJECTIVES:To provide descriptive epidemiological information on identified depression in nursing home residents. DESIGN:Survey of the 1996 Medical Expenditure Panel Survey-Nursing Home Component (MEPS-NHC). SETTING:Nine hundred fifty-one nursing facilities. PARTICIPANTS:Three thousand seven hundred ten noncomatose ...

    journal_title:Journal of the American Geriatrics Society

    pub_type: 杂志文章

    doi:10.1046/j.1532-5415.2003.51458.x

    authors: Jones RN,Marcantonio ER,Rabinowitz T

    更新日期:2003-10-01 00:00:00

  • Differences in oncologist communication across age groups and contributions to adjuvant decision outcomes.

    abstract::The objective of this study was to assess potential age-related differences in oncologist communication during conversations about adjuvant therapy decisions and subsequent patient decision outcomes. Communication was observed between a cross-section of female patients aged 40 to 80 with early-stage breast cancer (n=1...

    journal_title:Journal of the American Geriatrics Society

    pub_type: 杂志文章,随机对照试验

    doi:10.1111/j.1532-5415.2009.02512.x

    authors: Step MM,Siminoff LA,Rose JH

    更新日期:2009-11-01 00:00:00

  • Comparison of outcomes and the use of multimodality therapy in young and elderly people undergoing surgical resection of pancreatic cancer.

    abstract:OBJECTIVES:To compare outcomes and the use of multimodality therapy in young and elderly people with pancreatic cancer undergoing surgical resection. DESIGN:Retrospective, single-institution study. SETTING:National Cancer Institute/National Comprehensive Cancer Network cancer center. PARTICIPANTS:Two hundred three i...

    journal_title:Journal of the American Geriatrics Society

    pub_type: 杂志文章

    doi:10.1111/j.1532-5415.2011.03785.x

    authors: Barbas AS,Turley RS,Ceppa EP,Reddy SK,Blazer DG 3rd,Clary BM,Pappas TN,Tyler DS,White RR,Lagoo SA

    更新日期:2012-02-01 00:00:00

  • Suboptimal prescribing in elderly outpatients: potentially harmful drug-drug and drug-disease combinations.

    abstract:OBJECTIVES:To assess the prevalence and correlates of potentially harmful drug-drug combinations and drug-disease combinations prescribed for elderly patients at outpatient settings. DESIGN:Retrospective analysis of the 1995-2000 National Ambulatory Medical Care Survey (NAMCS) and the National Hospital Ambulatory Medi...

    journal_title:Journal of the American Geriatrics Society

    pub_type: 杂志文章

    doi:10.1111/j.1532-5415.2005.53112.x

    authors: Zhan C,Correa-de-Araujo R,Bierman AS,Sangl J,Miller MR,Wickizer SW,Stryer D

    更新日期:2005-02-01 00:00:00

  • Cost-Effectiveness and Public Health Effect of Influenza Vaccine Strategies for U.S. Elderly Adults.

    abstract:OBJECTIVES:To compare the cost-effectiveness of four influenza vaccines available in the United States for persons aged 65 and older: trivalent inactivated influenza vaccine (IIV3), quadrivalent inactivated influenza vaccine (IIV4), a more-expensive high-dose IIV3, and a newly approved adjuvanted IIV3. DESIGN:Cost-eff...

    journal_title:Journal of the American Geriatrics Society

    pub_type: 杂志文章

    doi:10.1111/jgs.14323

    authors: Raviotta JM,Smith KJ,DePasse J,Brown ST,Shim E,Nowalk MP,Zimmerman RK

    更新日期:2016-10-01 00:00:00

  • Clinico-neuropathological correlation of Alzheimer's disease in a community-based case series.

    abstract:OBJECTIVES:Most clinico-neuropathological correlative studies of Alzheimer's Disease (AD) are based on research cohorts that are not necessarily generalizable to patients seen in the general medical community. In this study, we examine the accuracy of the criteria used in diagnosing AD in a community-based case series ...

    journal_title:Journal of the American Geriatrics Society

    pub_type: 杂志文章

    doi:10.1111/j.1532-5415.1999.tb02571.x

    authors: Lim A,Tsuang D,Kukull W,Nochlin D,Leverenz J,McCormick W,Bowen J,Teri L,Thompson J,Peskind ER,Raskind M,Larson EB

    更新日期:1999-05-01 00:00:00

  • Proton Pump Inhibitors and Risk of Mild Cognitive Impairment and Dementia.

    abstract:OBJECTIVES:To examine the risk associated with the use of proton pump inhibitors (PPIs) of conversion to mild cognitive impairment (MCI), dementia, and specifically Alzheimer's disease (AD). DESIGN:Observational, longitudinal study. SETTING:Tertiary academic Alzheimer's Disease Centers funded by the National Institut...

    journal_title:Journal of the American Geriatrics Society

    pub_type: 杂志文章

    doi:10.1111/jgs.14956

    authors: Goldstein FC,Steenland K,Zhao L,Wharton W,Levey AI,Hajjar I

    更新日期:2017-09-01 00:00:00

  • The elderly patient in the coronary care unit. II. Incidence and treatment of arrhythmias.

    abstract::In 1976, 130 patients aged 70 or older were admitted to the Coronary Care Unit (CCU) at Toronto Western Hospital. Arrhythmias were noted in all but 24 percent. Digoxin was given to 53 patients, lidocaine to 24, propranolol to 28, and quinidine to 11. In 2 patients, cardioversion by direct current was required for supr...

    journal_title:Journal of the American Geriatrics Society

    pub_type: 杂志文章

    doi:10.1111/j.1532-5415.1979.tb06032.x

    authors: Berman ND

    更新日期:1979-05-01 00:00:00

  • Assessment of cognitive, psychiatric, and behavioral disturbances in patients with dementia: the Neurobehavioral Rating Scale.

    abstract:OBJECTIVE:To assess the validity of the Neurobehavioral Rating Scale (NRS) in patients with Alzheimer's disease (AD) or multi-infarct dementia (MID) and to characterize the cognitive, psychiatric, and behavioral disturbances that occur in these patients. DESIGN:Cross-sectional evaluation. SETTING:West Los Angeles VAM...

    journal_title:Journal of the American Geriatrics Society

    pub_type: 杂志文章

    doi:10.1111/j.1532-5415.1992.tb02101.x

    authors: Sultzer DL,Levin HS,Mahler ME,High WM,Cummings JL

    更新日期:1992-06-01 00:00:00

  • In-hospital use of continence aids and new-onset urinary incontinence in adults aged 70 and older.

    abstract:OBJECTIVES:To describe the types of continence aids that older adults hospitalized in acute medical units use and to test the association between use of continence aids and development of new urinary incontinence (UI) at discharge. DESIGN:Prospective cohort study. SETTING:A 900-bed teaching hospital in Israel. PARTI...

    journal_title:Journal of the American Geriatrics Society

    pub_type: 杂志文章

    doi:10.1111/j.1532-5415.2011.03413.x

    authors: Zisberg A,Sinoff G,Gur-Yaish N,Admi H,Shadmi E

    更新日期:2011-06-01 00:00:00

  • Calcium homeostasis of an elderly population upon admission to a nursing home.

    abstract:OBJECTIVE:To evaluate the skeletal health, calcium, and vitamin D homeostasis of patients upon their entry to a long-term-care facility. Factors that could contribute to the risk of future osteoporotic fractures were also evaluated. DESIGN:Cross-sectional study. PATIENTS:Two hundred eighty-seven consecutive admission...

    journal_title:Journal of the American Geriatrics Society

    pub_type: 杂志文章

    doi:10.1111/j.1532-5415.1993.tb06452.x

    authors: Komar L,Nieves J,Cosman F,Rubin A,Shen V,Lindsay R

    更新日期:1993-10-01 00:00:00

  • Electronic Medication Administration Records in Long-Term Care Facilities: A Scoping Review.

    abstract:OBJECTIVES:To map the extent, range, and nature of research on the effectiveness, level of use, and perceptions about electronic medication administration records (eMARs) in long-term care facilities (LTCFs) and identify gaps in current knowledge and priority areas for future research. DESIGN:Scoping review of quantit...

    journal_title:Journal of the American Geriatrics Society

    pub_type: 杂志文章,评审

    doi:10.1111/jgs.15384

    authors: Fuller AEC,Guirguis LM,Sadowski CA,Makowsky MJ

    更新日期:2018-07-01 00:00:00

  • African-American and white caregivers of older adults with dementia: differences in depressive symptomatology and psychotropic drug use.

    abstract:OBJECTIVES:To examine relationships between race and psychotropic drug use (antidepressant, antianxiety, sedative/hypnotic agents) in informal caregivers with symptoms of depression who provide care for elderly relatives with progressive dementia. Whether racial differences in medication use relate to racial difference...

    journal_title:Journal of the American Geriatrics Society

    pub_type: 杂志文章

    doi:10.1111/j.1532-5415.2005.53155.x

    authors: Sleath B,Thorpe J,Landerman LR,Doyle M,Clipp E

    更新日期:2005-03-01 00:00:00

  • Handgrip strength and mortality in older Mexican Americans.

    abstract:OBJECTIVES:To examine the association between handgrip strength and mortality in older Mexican American men and women. DESIGN:A 5-year prospective cohort study. SETTING:Five southwestern states: Texas, New Mexico, Colorado, Arizona, and California. PARTICIPANTS:A population-based sample of 2,488 noninstitutionalized...

    journal_title:Journal of the American Geriatrics Society

    pub_type: 杂志文章

    doi:10.1046/j.1532-5415.2002.50312.x

    authors: Al Snih S,Markides KS,Ray L,Ostir GV,Goodwin JS

    更新日期:2002-07-01 00:00:00

  • Mortality Risk Along the Frailty Spectrum: Data from the National Health and Nutrition Examination Survey 1999 to 2004.

    abstract:OBJECTIVES:To determine the relationship between frailty and overall and cardiovascular mortality. DESIGN:Longitudinal mortality analysis. SETTING:National Health and Nutrition Examination Survey (NHANES) 1999-2004. PARTICIPANTS:Community-dwelling older adults aged 60 and older (N = 4,984; mean age 71.1 ± 0.19, 56% ...

    journal_title:Journal of the American Geriatrics Society

    pub_type: 杂志文章

    doi:10.1111/jgs.15220

    authors: Crow RS,Lohman MC,Titus AJ,Bruce ML,Mackenzie TA,Bartels SJ,Batsis JA

    更新日期:2018-03-01 00:00:00

  • The significance of age-related enlargement of the cerebral ventricles in healthy men and women measured by quantitative computed X-ray tomography.

    abstract:OBJECTIVE:(1) To establish the range of cerebral atrophy across the adult age spectrum in optimally healthy, rigorously evaluated individuals. (2) To determine, across the age spectrum, the relation of gender and cerebral atrophy (as measured by ventricular enlargement) to cognitive function. DESIGN:Cross-sectional co...

    journal_title:Journal of the American Geriatrics Society

    pub_type: 杂志文章

    doi:10.1111/j.1532-5415.1992.tb02073.x

    authors: Kaye JA,DeCarli C,Luxenberg JS,Rapoport SI

    更新日期:1992-03-01 00:00:00