Stabilization of atherosclerotic plaques by blockade of macrophage migration inhibitory factor after vascular injury in apolipoprotein E-deficient mice.

abstract：:Coronary artery bypass surgery with or without aneurysmectomy has been used to treat patients with angiographically defined left ventricular aneurysm. To evaluate whether surgery benefits such patients, we analyzed the data from 1131 patients who were enrolled in the registry of the Coronary Artery Surgery Study. Four...

journal_title：Circulation

authors： Faxon DP,Myers WO,McCabe CH,Davis KB,Schaff HV,Wilson JW,Ryan TJ

更新日期：1986-07-01 00:00:00

abstract：:A case history of a 46-year-old Negro male was presented with rheumatic aortic insufficiency, angina pectoris, and possible subacute bacterial endocarditis. While hospitalized, the patient developed angina pectoris associated with micturition. This was not accompanied by a change in blood pressure, pulse, or increase ...

journal_title：Circulation

authors： Morris JJ,McIntosh HD

更新日期：1963-01-01 00:00:00

abstract：:Patients with heart failure frequently exhibit abnormal skeletal muscle metabolic responses to exercise, as assessed with 31P NMR. To investigate whether these metabolic abnormalities are due to intrinsic skeletal muscle changes, we performed gastrocnemius muscle biopsies on 22 patients with heart failure (peak VO2, 1...

journal_title：Circulation

authors： Mancini DM,Coyle E,Coggan A,Beltz J,Ferraro N,Montain S,Wilson JR

更新日期：1989-11-01 00:00:00

abstract：BACKGROUND:It is recommended that comatose survivors of out-of-hospital cardiac arrest should be cooled to 32° to 34°C for 12 to 24 hours. However, the optimal level of cooling is unknown. The aim of this pilot study was to obtain initial data on the effect of different levels of hypothermia. We hypothesized that deepe...

journal_title：Circulation

authors： Lopez-de-Sa E,Rey JR,Armada E,Salinas P,Viana-Tejedor A,Espinosa-Garcia S,Martinez-Moreno M,Corral E,Lopez-Sendon J

更新日期：2012-12-11 00:00:00

abstract：BACKGROUND:Cystic kidneys and vascular aneurysms are clinical manifestations seen in patients with polycystic kidney disease, a cilia-associated pathology (ciliopathy). Survivin overexpression is associated with cancer, but the clinical pathology associated with survivin downregulation or knockout has never been studie...

journal_title：Circulation

authors： Aboualaiwi WA,Muntean BS,Ratnam S,Joe B,Liu L,Booth RL,Rodriguez I,Herbert BS,Bacallao RL,Fruttiger M,Mak TW,Zhou J,Nauli SM

更新日期：2014-02-11 00:00:00

abstract：:Two-dimensional echocardiography can provide serial cross-sectional images of the left ventricular cavity. We examined whether such serial images from steady-state ejecting hearts would allow three-dimensional reconstruction and accurate volume estimation without major geometric assumptions. Cross-circulated, paced do...

journal_title：Circulation

authors： Eaton LW,Maughan WL,Shoukas AA,Weiss JL

更新日期：1979-08-01 00:00:00

abstract：BACKGROUND:Arterial grafts for CABG have been used increasingly, and the radial artery (RA) has become a preferable graft, secondary to the internal mammary artery (IMA). In the present study, we investigated and compared NO release and endothelium-derived hyperpolarizing factor (EDHF)-mediated hyperpolarization for IM...

journal_title：Circulation

authors： He GW,Liu ZG

更新日期：2001-09-18 00:00:00

abstract：:To compare acute effects of nitroglycerin (0.8 mg sublingually), nifedipine (5 ng/kg/min i.v.) and metoprolol (0.15 mg/kg i.v.) on normal, ischemic and scarred myocardial segments in man, we performed simultaneous hemodynamic and radionuclide measurements of left ventricular functions. Sixteen patients with isolated l...

journal_title：Circulation

authors： Pfisterer M,Glaus L,Burkart F

更新日期：1983-02-01 00:00:00

abstract：BACKGROUND:Household air pollution is the third largest risk factor for global disease burden, but direct links with cardiovascular disease mortality are limited. This study aimed to evaluate the relationship between household fuel use and cardiovascular disease mortality. METHODS AND RESULTS:The Golestan Cohort Study...

journal_title：Circulation

authors： Mitter SS,Vedanthan R,Islami F,Pourshams A,Khademi H,Kamangar F,Abnet CC,Dawsey SM,Pharoah PD,Brennan P,Fuster V,Boffetta P,Malekzadeh R

更新日期：2016-06-14 00:00:00

abstract：BACKGROUND:Cardiac tamponade is associated with fatal outcomes for patients with acute type A aortic dissection, and the presence of cardiac tamponade should prompt urgent aortic repair. However, treatment of the patient with critical cardiac tamponade who cannot survive until surgery remains unclear. We analyzed our e...

journal_title：Circulation

authors： Hayashi T,Tsukube T,Yamashita T,Haraguchi T,Matsukawa R,Kozawa S,Ogawa K,Okita Y

更新日期：2012-09-11 00:00:00

abstract：BACKGROUND:There is no consensus on how, when, or at what intensity exercise should be performed after heart transplantation (HTx). We have recently shown that high-intensity interval training (HIT) is safe, well tolerated, and efficacious in the maintenance state after HTx, but studies have not investigated HIT effect...

journal_title：Circulation

authors： Nytrøen K,Rolid K,Andreassen AK,Yardley M,Gude E,Dahle DO,Bjørkelund E,Relbo Authen A,Grov I,Philip Wigh J,Have Dall C,Gustafsson F,Karason K,Gullestad L

更新日期：2019-05-07 00:00:00

abstract：BACKGROUND:Inhaled nitric oxide (iNO) has been used to assess the vasodilator capacity of the pulmonary vascular bed in children with congenital heart disease and elevated pulmonary vascular resistance. Inhaled iloprost is a pulmonary vasodilator for the long-term treatment of pulmonary hypertension (PHT). Because thes...

journal_title：Circulation

authors： Rimensberger PC,Spahr-Schopfer I,Berner M,Jaeggi E,Kalangos A,Friedli B,Beghetti M

更新日期：2001-01-30 00:00:00

abstract：:Inherited thoracic aortopathies denote a group of congenital conditions that predispose to disease of the thoracic aorta. Aortic wall weakness and abnormal aortic hemodynamic profiles predispose these patients to dilatation of the thoracic aorta, which is generally silent but can precipitate aortic dissection or ruptu...

journal_title：Circulation

authors： Fletcher AJ,Syed MBJ,Aitman TJ,Newby DE,Walker NL

更新日期：2020-05-12 00:00:00

abstract：:The time of acute myocardial infarction was determined in all 1,741 patients of the ISAM (Intravenous Streptokinase in Acute Myocardial Infarction) Study, based on onset of clinical symptoms and evaluation of plasma CK-MB enzyme time-activity curves. The incidence of myocardial infarction was markedly increased betwee...

journal_title：Circulation

authors： Willich SN,Linderer T,Wegscheider K,Leizorovicz A,Alamercery I,Schröder R

更新日期：1989-10-01 00:00:00

abstract：BACKGROUND:The Bleeding Academic Research Consortium (BARC) has recently proposed a unified definition of bleeding in patients receiving antithrombotic therapy. We investigated the relationship between bleeding events as defined by BARC and 1-year mortality in patients undergoing percutaneous coronary intervention (PCI...

journal_title：Circulation

authors： Ndrepepa G,Schuster T,Hadamitzky M,Byrne RA,Mehilli J,Neumann FJ,Richardt G,Schulz S,Laugwitz KL,Massberg S,Schömig A,Kastrati A

更新日期：2012-03-20 00:00:00

abstract：:Coronary artery bypass grafts, angioplasty, and thrombolysis are beneficial procedures for patients with coronary artery disease. However, these procedures can fail by mechanisms related to interactions between platelets and the damaged arterial wall. An experimental model for studying some of the mechanisms of platel...

journal_title：Circulation

authors： Folts J

更新日期：1991-06-01 00:00:00

abstract：:Despite the clinical prevalence of paradoxic interventricular septal (IVS) motion, its pathogenesis remains unclear. To assess the influence of the end-diastolic transseptal pressure gradient, we studied eight open-chest dogs during right ventricular (RV) volume loading (induced by opening a Dacron shunt between the p...

journal_title：Circulation

authors： Kingma I,Tyberg JV,Smith ER

更新日期：1983-12-01 00:00:00

abstract：BACKGROUND:Peroxisome proliferator-activated receptor-gamma (PPAR-gamma) agonists inhibit vascular smooth muscle proliferation and migration and improve endothelial function. It is unknown whether PPAR-gamma agonists favorably modulate bone marrow (BM)-derived angiogenic progenitor cells (APCs) to promote endothelial l...

journal_title：Circulation

authors： Wang CH,Ciliberti N,Li SH,Szmitko PE,Weisel RD,Fedak PW,Al-Omran M,Cherng WJ,Li RK,Stanford WL,Verma S

更新日期：2004-03-23 00:00:00

abstract：:From January 1968 to June 1975 tricuspid regurgitation was encountered in 238 patients of a total of 1074 patients undergoing operations on the mitral valve. During this time tricuspid annuloplasty (TA) was performed in 137 patients and the tricuspid valve was replaced (TVR) in 101 patients. Comparison of hospital mor...

journal_title：Circulation

authors： Reed GE,Boyd AD,Spencer FC,Engelman RM,Isom OW,Cunningham JN Jr

更新日期：1976-12-01 00:00:00

abstract：BACKGROUND:The aim of this prospective, randomized study was to examine whether additional school exercise lessons would result in improved peak oxygen uptake (primary end point) and body mass index-standard deviation score, motor and coordinative abilities, circulating progenitor cells, and high-density lipoprotein ch...

journal_title：Circulation

authors： Walther C,Gaede L,Adams V,Gelbrich G,Leichtle A,Erbs S,Sonnabend M,Fikenzer K,Körner A,Kiess W,Bruegel M,Thiery J,Schuler G

更新日期：2009-12-01 00:00:00

abstract：BACKGROUND:For patients with in-hospital cardiac arrests attributable to nonshockable rhythms, delays in epinephrine administration beyond 5 minutes is associated with worse survival. However, the extent of hospital variation in delayed epinephrine administration and its effect on hospital-level outcomes is unknown. M...

journal_title：Circulation

authors： Khera R,Chan PS,Donnino M,Girotra S,American Heart Association’s Get With The Guidelines-Resuscitation Investigators.

更新日期：2016-12-20 00:00:00

abstract：:In a study of aerobically perfused rat hearts, the in situ photoactivation (530-590 nm) of rose bengal (a process that leads to the production of singlet oxygen and superoxide) has been shown to lead to the rapid development of electrocardiographic abnormalities and arrhythmias. With rose bengal concentrations of 1,00...

journal_title：Circulation

authors： Kusama Y,Bernier M,Hearse DJ

更新日期：1989-11-01 00:00:00

abstract：:Retrograde coronary artery flow was observed angiographically in 43 patients with aortic stenosis and/or regurgitation. In the 24 patients with pure or predominant aortic stenosis, retrograde flow was seen in all 24 during end-systole. In the eight patients with pure aortic regurgitation, retrograde flow was seen main...

journal_title：Circulation

authors： Carroll RJ,Falsetti HL

更新日期：1976-09-01 00:00:00

abstract：:The present study was performed to determine whether positron emission tomography (PET) performed after i.v. 11C-palmitate permits detection and characterization of nontransmural myocardial infarction. PET was performed after the i.v. injection of 11C-palmitate in 10 normal subjects, 24 patients with initial nontransm...

journal_title：Circulation

authors： Geltman EM,Biello D,Welch MJ,Ter-Pogossian MM,Roberts R,Sobel BE

更新日期：1982-04-01 00:00:00

abstract：BACKGROUND:Autosomal dominant hypercholesterolemia (ADH) is characterized by elevated low-density lipoprotein cholesterol levels and premature cardiovascular disease. Mutations in the genes encoding for low-density lipoprotein receptor (LDLR), apolipoprotein B (APOB), and proprotein convertase subtilisin/kexin 9 (PCSK9...

journal_title：Circulation

authors： van der Graaf A,Avis HJ,Kusters DM,Vissers MN,Hutten BA,Defesche JC,Huijgen R,Fouchier SW,Wijburg FA,Kastelein JJ,Wiegman A

更新日期：2011-03-22 00:00:00

abstract：BACKGROUND:Previous studies have demonstrated that induction of heat shock protein (HSP) 72 by whole-body hyperthermia reduces infarct size in an in vivo model of ischemia and reperfusion. Furthermore, hearts obtained from transgenic mice that overexpress HSP72 demonstrate improved functional recovery and decreased inf...

journal_title：Circulation

authors： Hutter JJ,Mestril R,Tam EK,Sievers RE,Dillmann WH,Wolfe CL

更新日期：1996-09-15 00:00:00

abstract：:Congestive heart failure is often preceded by a latent or preclinical phase in which patients are relatively asymptomatic. During this period, there is neuroendocrine activation, left ventricular dysfunction, and remodeling of the heart. The extent to which these activities are interrelated is unclear, but it appears ...

journal_title：Circulation

authors： Francis GS,McDonald KM,Cohn JN

更新日期：1993-05-01 00:00:00

abstract：BACKGROUND:Doxycycline has been shown to effectively inhibit aneurysm formation in animal models of abdominal aortic aneurysm. Although this effect is ascribed to matrix metalloproteinase-9 inhibition, such an effect is unclear in human studies. We reevaluated the effect of doxycycline on aortic wall protease content i...

journal_title：Circulation

authors： Lindeman JH,Abdul-Hussien H,van Bockel JH,Wolterbeek R,Kleemann R

更新日期：2009-04-28 00:00:00

abstract：BACKGROUND:HMG CoA reductase inhibitors (or statins), a new class of lipid-lowering compounds, have raised expectations for more widespread use than that of the older lipid-lowering drugs. Not only are they more effective in lowering LDL cholesterol, but they are better tolerated as well. No data exist concerning the e...

journal_title：Circulation

authors： Furberg CD,Adams HP Jr,Applegate WB,Byington RP,Espeland MA,Hartwell T,Hunninghake DB,Lefkowitz DS,Probstfield J,Riley WA

更新日期：1994-10-01 00:00:00

abstract：BACKGROUND:Biventricular direct cardiac compression (DCC) has the potential to support the failing heart without the complications associated with a blood/device interface encountered with the use of current ventricular assist devices. A clinically designed DCC device that provides compression pressure around the base ...

journal_title：Circulation

authors： Artrip JH,Yi GH,Levin HR,Burkhoff D,Wang J

更新日期：1999-11-09 00:00:00