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Differential modulation of the antifungal activity of amphotericin B by natural and ent-cholesterol.

Abstract：

:The addition of exogenous ent-cholesterol suppressed the antifungal activity of the amphotericin B when added to cultures of Candida albicans, but to a lesser extent than natural cholesterol. There were no detectable differences between added 2a or 2b on the antifungal activities of jaspamide or bengazole A, two unrelated antifungal natural products.

journal_name

Bioorg Med Chem Lett

journal_title

Bioorganic & medicinal chemistry letters

authors

Richter RK,Mickus DE,Rychnovsky SD,Molinski TF

doi

10.1016/j.bmcl.2003.10.018

subject

Has Abstract

pub_date

2004-01-05 00:00:00

pages

115-8

issue

1

eissn

0960-894X

issn

1464-3405

pii

S0960894X03010564

journal_volume

14

pub_type

杂志文章

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