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3-Methoxycarbonyl-5-nitrophenyl boronic acid: high affinity diol recognition at neutral pH.

Abstract：

:Several boronic acids were screened for their ability to bind to diols. 3-methoxycarbonyl-5-nitrophenyl boronic acid bound to both a catechol dye as well as fructose with a comparable affinity to that of an ortho-methylamino substituted boronic acid. This work suggests a greater role for appropriately functionalized electron deficient boronic acids in diol and carbohydrate recognition.

journal_name

Bioorg Med Chem Lett

journal_title

Bioorganic & medicinal chemistry letters

authors

Mulla HR,Agard NJ,Basu A

doi

10.1016/j.bmcl.2003.10.017

subject

Has Abstract

pub_date

2004-01-05 00:00:00

pages

25-7

issue

1

eissn

0960-894X

issn

1464-3405

pii

S0960894X03011016

journal_volume

14

pub_type

杂志文章

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