Immunohistochemical determination of HER-2/neu in malignant melanoma.

abstract：BACKGROUND:Due to the longer life expectancy of the world's population, the number of elderly cirrhotic patients undergoing surgery for hepatocellular carcinoma (HCC) is increasing. Our study evaluates the benefits of hepatic resections for HCC in cirrhotic patients aged over 65, analysing the early and long-term surgi...

journal_title：Anticancer research

authors： Mercantini P,Corigliano N,Lucandri G,Balducci G,Amodio PM,Ramacciato G,Ziparo V

更新日期：2002-11-01 00:00:00

abstract：:The purpose of the present study was to compare the therapeutic efficacy of the alpha-emitter Astatine-211 with the beta-emitter Iodine-131 bound to the specific monoclonal antibody MOv18. The measurements were performed in an ovarian cancer cell line (NIH:OVCAR 3) growing intraperitoneally in nude mice. Two weeks aft...

journal_title：Anticancer research

authors： Andersson H,Palm S,Lindegren S,Bäck T,Jacobsson L,Leser G,Horvath G

更新日期：2001-01-01 00:00:00

abstract：:Game theory can be a powerful tool for generating testable hypotheses concerning biological systems. We present a simple game that has many features analogous to a developing cellular system. The game mimics random turning on of genes in cells. Despite the randomness explicit in the mechanism, the game nonetheless res...

journal_title：Anticancer research

authors： Root-Bernstein RS,Bernstein MI

更新日期：1999-11-01 00:00:00

abstract：BACKGROUND/AIM:We investigated the effect of aspirin on colorectal cancer (CRC) risk among subgroups of women with and without risk factors for CRC. PATIENTS AND METHODS:Using data from the Women's Health Initiative, we estimated hazard ratios for CRC in association with aspirin use, with stratifications by cardiovasc...

journal_title：Anticancer research

authors： Seaton ME,Peters U,Johnson KC,Kooperberg C,Bafford A,Zubair N

更新日期：2019-09-01 00:00:00

abstract：:Development of multidrug-resistance (MDR) remains a major cause of failure in the treatment of cancer with chemotherapeutic agents. In our efforts to explore alternative treatment regimens for multidrug-resistant tumors we have examined the sensitivity of MDR tumor cell lines to lymphokine activated killer (LAK) cells...

journal_title：Anticancer research

authors： Gautam SC,Chikkala NF,Lewis I,Grabowski DR,Finke JH,Ganapathi R

更新日期：1992-05-01 00:00:00

abstract：PURPOSE:To investigate the optimal duration of oral HCFU administration for minimization of side effects induced by long-term administration. PATIENTS AND METHODS:In total, 155 patients allocated to two groups of different duration of the therapy were reviewed: twice or three times per day doses of oral HCFU (8 mg/Kg ...

journal_title：Anticancer research

authors： Ito K,Kato T,Koike A,Miura K,Yamaguchi A,Sakou T,Takagi H

更新日期：2000-11-01 00:00:00

abstract：BACKGROUND:In the present study, we examined the relationships between microsatellite status and Ki-67 labeling index, a proliferative marker, in colorectal cancers in order to clarify the common biological profiles of familial and sporadic cases of MSI (microsatellite inability)-positive tumors. PATIENTS AND METHODS:...

journal_title：Anticancer research

authors： Takagi S,Kumagai S,Kinouchi Y,Hiwatashi N,Nagashima F,Takahashi S,Shimosegawa T

更新日期：2002-11-01 00:00:00

abstract：:Rats were inoculated subcutaneously into both flanks with a transplantable adenocarcinoma of the colon. They were treated intravenously with either 5-FUrd (5-fluorouridine) or 5-FdUrd (5-fluoro-2'-deoxyuridine) with or without addition of dipyridamole 20 and 30 min later, respectively, for 3 consecutive days. Dipyrida...

journal_title：Anticancer research

authors： el Hag IA,Roos G,Jönsson PE,Stenram U

更新日期：1990-01-01 00:00:00

abstract：:Over 600 analogues of mitomycin C (MMC) have been made in the past and more recently a number of Mitomycin A (MMA) derivatives have been prepared. Since many of the MMA type had the same organic side chain at the 7-position as previously prepared MMC analogues it was of interest to see if the biological effects of MMC...

journal_title：Anticancer research

authors： Bradner WT,Remers WA,Vyas DM

更新日期：1989-07-01 00:00:00

abstract：:Our previous work showed that low-power wide-band millimeter waves (MMW) inhibit the growth of the MCF-7 human breast carcinoma cell line, also causing a marked reduction of the density of microvilli at the apical membrane of the MCF-7 cells, as revealed by scanning electron microscopy. The aim of the present work was...

journal_title：Anticancer research

authors： Beneduci A,Chidichimo G,Tripepi S,Perrotta E

更新日期：2005-03-01 00:00:00

abstract：:P53 mutation, through defects in repairing DNA damages, is associated with genomic instability. In 24 adult patients with relapsed acute lymphoblastic leukemia (ALL), the status of the p53 gene at different stages was serially followed by cytogenetic and polymerase-chain reaction/single strand conformation polymorphis...

journal_title：Anticancer research

authors： Tang JL,Tien HF,Lin MT,Chen PJ,Chen YC

更新日期：1998-03-01 00:00:00

abstract：:The model of human malignant tumors, heterotransplanted and passaged into athymic nude mice, proved to be a valuable tool for nutritional oncology. It showed that several human tumors proliferate in distinct dependence on the available vitamin B6. A surplus of the vitamin causes enhancement of growth. Proliferation is...

journal_title：Anticancer research

authors： Fortmeyer HP,Timm C,Blum U,Wenisch HJ,Förster H

更新日期：1988-07-01 00:00:00

abstract：BACKGROUND:MicroRNAs (miRNAs), which are endogenously expressed regulatory noncoding RNAs, have an altered expression in tumor tissues. MiRNAs regulate cancer-related processes such as cell growth and tissue differentiation, and therefore, might function as oncogenes or tumor-suppressor genes. The aim of our study was ...

journal_title：Anticancer research

authors： Pesta M,Klecka J,Kulda V,Topolcan O,Hora M,Eret V,Ludvikova M,Babjuk M,Novak K,Stolz J,Holubec L

更新日期：2010-09-01 00:00:00

abstract：:African-American women with breast cancer consistently show a shortened survival when compared with Caucasians with breast cancer, however it is not clear whether this is due to socioeconomic factors or to racial differences in tumor biology. Cyclin D1 overexpression has been demonstrated in 60-80% of female breast ca...

journal_title：Anticancer research

authors： Joe AK,Arber N,Bose S,Heitjan D,Zhang Y,Weinstein IB,Hibshoosh H

更新日期：2001-09-01 00:00:00

abstract：:Mouthwashes are widespread used to treat halitosis or minor oral infections. Adverse effects of mouthwashes were recognized, e.g. desquamation of the oral mucosa and stomatitis. The acute toxicity of mouthwashes was tested in an in vitro system, the pollen tube growth test (PTG-test). In the PTG-test the acute toxicit...

journal_title：Anticancer research

authors： Friedrich RE,Kristen U

更新日期：1999-07-01 00:00:00

abstract：BACKGROUND/AIM:The aim of this study was to analyze the pretreatment cytokeratin serum levels in head and neck squamous cell carcinoma (HNSCC) by three assays in relation to selected clinicopathological characteristics in an effort to find diagnostic/prognostic biomarkers for HNSCC and determine the best assay. PATIEN...

journal_title：Anticancer research

authors： Kalfert D,Ludvik J,Kucera R,Topolcan O,Celakovsky P,Pesta M,Kholova I,Plzak J,Ludvikova M

更新日期：2019-09-01 00:00:00

abstract：:Exposure of human promyelocytic leukemic HL-60 cells to millimolar concentration of sodium ascorbate induced apoptotic cell death. The extent of apoptosis induction was a positive function of temperature at the time of exposure. The incorporation of [1-14C] ascorbic acid into the cytosolic fraction of HL-60 cells was ...

journal_title：Anticancer research

authors： Amano Y,Sakagami H,Tanaka T,Yamanaka Y,Nishimoto Y,Yamaguchi M,Takeda M

更新日期：1998-07-01 00:00:00

abstract：:Peptides extracted from tumor cells after mild acid treatment can function as antigenic epitopes when presented by cultured dendritic cells. Peptides were extracted from four tumors syngeneic to C3H mice, three weakly immunogenic tumors (FSA, MCAK, HCA) and one non-immunogenic tumor (NFSA). Dendritic cells pulsed with...

journal_title：Anticancer research

authors： Ribas A,Bui LA,Butterfield LH,Vollmer CM,Jilani SM,Dissette VB,Glaspy JA,McBride WH,Economou JS

更新日期：1999-03-01 00:00:00

abstract：:The triphenylmethane derivative, aurintricarboxylic acid (ATA), but not aurin, is a potent inhibitor of angiogenesis in the chick chorioallantoic membrane. ATA alone showed potent anti-angiogenic activity in a dose-related manner. The presence of heparin or bFGF decreased the anti-angiogenic activity of ATA. ATA also ...

journal_title：Anticancer research

authors： Gagliardi AR,Collins DC

更新日期：1994-03-01 00:00:00

abstract：BACKGROUND:Oxaliplatin (L-OHP), active in a wide range of human and animal tumours, also CDDP-resistant, possesses unique molecular characteristics of action. However, the mechanisms by which the damage induced by L-OHP triggers a death signal are not yet fully defined. MATERIALS AND METHODS:After L-OHP treatment of t...

journal_title：Anticancer research

authors： Marchetti P,Galla DA,Russo FP,Ricevuto E,Flati V,Porzio G,Ficorella C,Cifone MG

更新日期：2004-01-01 00:00:00

abstract：:Mutations affecting the mechanistic target of rapamycin (MTOR) signalling pathway are frequent in human cancer and have been identified in up to 15% of pancreatic neuroendocrine tumours (NETs). Grade A evidence supports the efficacy of MTOR inhibition with everolimus in pancreatic NETs. Although a significant proporti...

journal_title：Anticancer research

authors： Backman S,Norlén O,Eriksson B,Skogseid B,Stålberg P,Crona J

更新日期：2017-02-01 00:00:00

abstract：BACKGROUND:Concurrent chemoradiotherapy (CCRT) is used to treat advanced head and neck cancer. The accuracy of evaluating lymph nodes metastases following CCRT is important for subsequent therapy. PATIENTS AND METHODS:Patients were divided into two groups, the complete response (CR) and the non-CR groups, as determine...

journal_title：Anticancer research

authors： Nishimura G,Matsuda H,Taguchi T,Takahashi M,Komatsu M,Sano D,Sakuma N,Arai Y,Takahashi H

更新日期：2012-02-01 00:00:00

abstract：:In the clinical setting, administration of high daily or bolus doses of vitamin D is often solely based on 25-hydroxyvitamin D [25(OH)D] testing. This review summarizes the evidence of the effect of vitamin D on cardiovascular disease (CVD). Meta-analyses of randomized controlled trials (RCTs) have demonstrated that C...

journal_title：Anticancer research

authors： Zittermann A,Pilz S

更新日期：2019-09-01 00:00:00

abstract：:Renal cell carcinoma (RCC) is one of the few tumour types metastatic to the pancreas. In order to evaluate the outcome following resection of pancreatic metastases of RCC a retrospective review of surgical patients was performed. The initial histopathological staging, disease-free interval, surgical outcome and surviv...

journal_title：Anticancer research

authors： Schauer M,Vogelsang H,Siewert JR

更新日期：2008-01-01 00:00:00

abstract：:Urinary gonadotropin peptide (UGP) has been measured in gynecological and urological cancers, but its usefulness in the diagnosis of cancers of digestive organs has not been investigated. In this report, UGP was measured by sandwich enzyme immunoassay in 311 patients, including 166 patients with cancers of digestive o...

journal_title：Anticancer research

authors： Motoo Y,Watanabe H,Yamaguchi Y,Mouri I,Fujii T,Yamakawa O,Satomura Y,Okai T,Sawabu N

更新日期：1996-07-01 00:00:00

abstract：BACKGROUND:3-Chloro-4-(dichloromethyl)-5-hydroxy-2(5H)-furanone (MX), a disinfection by-product in chlorinated drinking water, induces follicular tumors in thyroid glands in Wistar rats. The mechanisms of the MX-induced thyroid gland tumorigenesis are not known. MATERIALS AND METHODS:The expressions of p53 (primary an...

journal_title：Anticancer research

authors： Hakulinen P,Kosma VM,Komulainen H

更新日期：2002-03-01 00:00:00

abstract：BACKGROUND:Cancer stem cells (CSCs) are tumour-initiating cells with self-renewal properties and chemo/radio-resistance. Regulatory T-cells (Tregs) influence CSCs through several mechanisms. In different solid tumours, the presence of both cell populations correlated with poor survival. In vulvar cancer, little is know...

journal_title：Anticancer research

authors： Napoletano C,Bellati F,Ruscito I,Pernice M,Zizzari IG,Caponnetto S,Tomao F,Frigerio L,Liberati M,Rughetti A,Caserta D,Panici PB,Nuti M

更新日期：2016-10-01 00:00:00

abstract：BACKGROUND/AIM:This study assessed the toxicity and activity of biweekly docetaxel and S-1 combination therapy in elderly patients with advanced gastric cancer. PATIENTS AND METHODS:One-hundred and thirteen patients were enrolled: 35 were 75 years old or more. The objective response rate, toxicity, progression-free su...

journal_title：Anticancer research

authors： Kunisaki C,Takahashi M,Ono HA,Hasegawa S,Tsuchida K,Oshima T,Ota M,Fukushima T,Tokuhisa M,Izumisawa Y,Takagawa R,Kimura J,Kosaka T,Makino H,Akiyama H,Endo I

更新日期：2013-02-01 00:00:00

abstract：UNLABELLED:Malignant pleural mesothelioma is a rare tumour. A three-modal strategy, comprising of surgery, radiotherapy and chemotherapy has been shown to be essential for appropriate management. Current literature evidences the importance of radiation therapy in the adjuvant setting for local control of the disease, a...

journal_title：Anticancer research

authors： Takanen S,Resuli B,Graziano V,Parisi A,Lisi R,Raffetto N,Tombolini V

更新日期：2012-04-01 00:00:00

abstract：BACKGROUND:Carcinoma of the ampulla of Vater is an infrequent tumor that can be diagnosed, early. PATIENTS AND METHODS:Twenty-four patients with histologically proven carcinoma of the ampulla of Vater were retrospectively studied and their data were analyzed. RESULTS:Most common presenting symptoms were jaundice (67%...

journal_title：Anticancer research

authors： Mouzas IA,Skordilis P,Frangiadakis N,Leondidis C,Alexandrakis G,Potamianos S,Kouroumalis E,Manousos ON

更新日期：1999-09-01 00:00:00