Abstract:
PURPOSE:To report a patient with Neisseria meningitidis endophthalmitis without associated meningitis with full visual recovery, with early detection of the microorganism using polymerase chain reaction (PCR) analysis. DESIGN:Retrospective, observational case report. PARTICIPANTS:One patient with endogenous endophthalmitis. METHODS:Polymerase chain reaction analysis and culture of the intraocular fluid sample. Polymerase chain reaction analysis was performed with a universal (16S rRNA) primer set to detect bacterial DNA, and subsequently a specific probe was used to detect Neisseria species DNA. RESULTS:The 16S rRNA primers detected bacterial DNA, the specific probe detected Neisseria species DNA, and culture was positive for Neisseria meningitidis serotype C. CONCLUSIONS:A universal bacterial PCR can be very helpful for the diagnosis of endogenous bacterial endophthalmitis at an early stage of the disease.
journal_name
Ophthalmologyjournal_title
Ophthalmologyauthors
Kerkhoff FT,van der Zee A,Bergmans AM,Rothova Adoi
10.1016/S0161-6420(03)00834-0subject
Has Abstractpub_date
2003-11-01 00:00:00pages
2134-6issue
11eissn
0161-6420issn
1549-4713pii
S0161-6420(03)00834-0journal_volume
110pub_type
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