Abstract：
:This investigation was conducted to determine the ability of 201Tl brain SPECT with respect to preoperative prediction of lesional aggressiveness of meningioma. Fifty-nine lesions in 42 patients were examined. Early (15 min) and late (3 h) SPECT were obtained. Early uptake ratio (ER; lesion to normal brain average count ratio), late uptake ratio (LR) and the ratio of LR to ER (L/E ratio) were calculated. Twenty-three lesions exhibited malignant features based on histologic or clinical course such as recurrence or skull invasion. Both ER and LR of malignant meningiomas were significantly higher than those in thirty-six benign lesions. Benign lesions were classified into two groups for further analysis: meningotheliomatous type, which is the most common histology, and benign lesions other than the meningotheliomatous (other benign) type. ER in other benign type was lower than the meningotheliomatous and the malignant type. LR afforded differentiation of the malignant type from the two benign types. These two benign types could be distinguished on the basis of the L/E ratio. These results indicate that high pre-operative ER and LR values in patients with meningioma are indicators of the aggressiveness of lesions, i.e., malignant meningioma, recurrence or skull invasion.
journal_name
Ann Nucl Medjournal_title
Annals of nuclear medicineauthors
Kinuya K,Ohashi M,Itoh S,Sakai S,Yamamoto K,Kakuda K,Nobata K,Terahata S,Taki S,Kinuya Sdoi
10.1007/BF03006435subject
Has Abstractpub_date
2003-09-01 00:00:00pages
463-7issue
6eissn
0914-7187issn
1864-6433journal_volume
17pub_type
临床试验,杂志文章abstract：:Iodine-131 metaiodobenzylguanidine ((131)I-MIBG) therapy is an effective treatment for patients with malignant paraganglioma for which surgical resection is not indicated. We performed high-dose (131)I-MIBG therapy on two patients with malignant paraganglioma and multiple bone metastases. The bone metastases were diag...
journal_title：Annals of nuclear medicine
pub_type： 杂志文章
doi：10.1007/s12149-007-0020-4
更新日期：2007-07-01 00:00:00
abstract：OBJECTIVE:This study aims to clarify the effect of renal function on 2-[(18)F] fluoro-2-deoxy-D-glucose positron emission tomography (FDG-PET) imaging and determine the clinical significance of renal function in this setting. We compared FDG distribution between normal volunteers and patients with suspected renal failu...
journal_title：Annals of nuclear medicine
pub_type： 杂志文章
doi：10.1007/s12149-007-0012-4
更新日期：2007-06-01 00:00:00
abstract：OBJECTIVE:The potential of positron emission tomography/computed tomography using 62Cu-diacetyl-bis (N4-methylthiosemicarbazone) (62Cu-ATSM PET/CT), which was originally developed as a hypoxic tracer, to predict therapeutic resistance and prognosis has been reported in various cancers. Our purpose was to investigate pr...
journal_title：Annals of nuclear medicine
pub_type： 临床试验,杂志文章
doi：10.1007/s12149-018-1241-4
更新日期：2018-05-01 00:00:00
abstract：BACKGROUND:Exact localization of recurrent iodine-negative thyroid cancer is mandatory, since surgery is the only curative therapy option in patients with iodine-negative tumor tissue. The aim of this study was to evaluate the impact of (18)F-FDG-PET/CT as a routine diagnostic tool on clinical management in patients wi...
journal_title：Annals of nuclear medicine
pub_type： 杂志文章
doi：10.1007/s12149-011-0545-4
更新日期：2012-01-01 00:00:00
abstract：OBJECTIVE:To assess the role of serial FLT-PET scans during early neoadjuvant treatment as a prognostic marker of response to treatment and survival. METHODS:This study is a prospective cohort study which draws from a larger original study which examined the utility of FLT-PET imaging across multiple cancers. Our coho...
journal_title：Annals of nuclear medicine
pub_type： 临床试验,杂志文章
doi：10.1007/s12149-019-01345-w
更新日期：2019-06-01 00:00:00
abstract：OBJECTIVE:In this study, the feasibility and kinetic characteristics of the (68)Ga-NOTA-RGD, a recently developed RGD peptide agent, were investigated for atherosclerosis imaging in comparison with (18)FDG. METHODS:ApoE(-/-) mice were fed a high-fat diet for more than 20 weeks. To evaluate the feasibility, tissue upta...
journal_title：Annals of nuclear medicine
pub_type： 杂志文章
doi：10.1007/s12149-013-0757-x
更新日期：2013-11-01 00:00:00
abstract：BACKGROUND:Rest thallium-201 (201Tl) myocardial perfusion imaging has been widely used for evaluation of myocardial ischemia/viability after myocardial infarction, but the ideal timing for imaging after injection to maximally estimate viability is not well established. METHODS:Thirty-six patients with myocardial infar...
journal_title：Annals of nuclear medicine
pub_type： 临床试验,杂志文章
doi：10.1007/BF02985586
更新日期：2006-01-01 00:00:00
abstract：PURPOSE:The aim of this study is to specify the precise role of bone scintigraphy and serum CEA and CA 15-3 assays in the monitoring of breast cancers in order to optimize their use and to determine whether it is possible to guide the prescription of bone scan by the use of CEA and CA 15-3 assays in the monitoring of b...
journal_title：Annals of nuclear medicine
pub_type： 杂志文章
doi：10.1007/BF02984567
更新日期：2004-09-01 00:00:00
abstract：:We report a functional neuroimaging study of a patient clinically diagnosed with Korsakoff syndrome. Positron emission tomography (PET) with the 15O inhalation method showed decreased regional cerebral blood flow (rCBF) and decreased regional cerebral metabolic ratio for oxygen (rCMRO2) in the bilateral fronto-tempora...
journal_title：Annals of nuclear medicine
pub_type： 杂志文章
doi：10.1007/BF03164755
更新日期：1997-02-01 00:00:00
abstract：:The aim of this study is to re-evaluate and clarify the diagnostic role of ventilation/perfusion lung scintigraphy in Japan, now that single-detector-row helical CT and multidetector-row CT are available in clinical practice. The Respiratory Nuclear Medicine Working Group of the Japanese Society of Nuclear Medicine di...
journal_title：Annals of nuclear medicine
pub_type： 杂志文章
doi：10.1007/BF02988632
更新日期：2002-12-01 00:00:00
abstract：:To evaluate two methods for decreasing and/or diluting the FDG activity in the urinary system, five rats were intraperitoneally given 1,000 micrograms/g of L-lysine 4 times, starting from 60 minutes before iv injection of FDG, and then at 30-minute intervals for 90 minutes. Five rats were used as controls. In a furose...
journal_title：Annals of nuclear medicine
pub_type： 杂志文章
doi：10.1007/BF03164766
更新日期：1997-08-01 00:00:00
abstract：BACKGROUND:The aim of the study was to compare widely used ordered subset expectation maximisation (OSEM) algorithm with a new Bayesian penalised likelihood (BPL) Q.Clear algorithm in 18F-PSMA-1007 PET/CT. METHODS:We retrospectively assessed 25 18F-PSMA-1007 PET/CT scans with both OSEM and Q.Clear reconstructions avai...
journal_title：Annals of nuclear medicine
pub_type： 杂志文章
doi：10.1007/s12149-019-01433-x
更新日期：2020-03-01 00:00:00
abstract：OBJECTIVE:The purpose of this study was to investigate the diagnostic performance of postoperative fluorine-18 fluoro-2-deoxy-D-glucose ((18)F-FDG) positron emission tomography/computed tomography (PET/CT) as a surveillance modality for advanced gastric cancer patients who were asymptomatic and negative by conventional...
journal_title：Annals of nuclear medicine
pub_type： 杂志文章
doi：10.1007/s12149-014-0871-4
更新日期：2014-10-01 00:00:00
abstract：:A method has been described to optimize the cutoff frequency of the Butterworth filter for brain SPECT imaging. Since a computer simulation study has demonstrated that separation between an object signal and the random noise in projection images in a spatial-frequency domain is influenced by the total number of counts...
journal_title：Annals of nuclear medicine
pub_type： 杂志文章
doi：10.1007/BF03164571
更新日期：1993-05-01 00:00:00
abstract：:A 39-year-old woman with acute cholecystitis and gallstones underwent laparoscopic cholecystectomy. She suffered from recurrent episodes of cholangitis due to injury of the major bile ducts during laparoscopic cholecystectomy. Hepatobiliary scintigraphy with Tc-99m Sn-N-pyridoxyl-5-methyltryptophan was performed. Alth...
journal_title：Annals of nuclear medicine
pub_type： 杂志文章
doi：10.1007/BF02988702
更新日期：2000-10-01 00:00:00
abstract：OBJECTIVE:To demonstrate the effect of clinicopathological factors on 68Ga-PSMA-11 PET/CT positivity at the time of biochemical recurrence (BCR) of localized prostate cancer (PCa) following definitive therapy. METHODS:We retrospectively reviewed our institutional database for PCa patients who had BCR and subsequently ...
journal_title：Annals of nuclear medicine
pub_type： 杂志文章
doi：10.1007/s12149-019-01340-1
更新日期：2019-05-01 00:00:00
abstract：OBJECTIVES:Nowadays, the number of primary studies on fluorodeoxyglucose (FDG) positron emission tomography/computed tomography (PET/CT) has been increasing rapidly. Thus, we updated meta-analysis to evaluate the test performance of FDG PET/CT for nodal staging in non-small cell lung cancer (NSCLC) including the most r...
journal_title：Annals of nuclear medicine
pub_type： 杂志文章,meta分析
doi：10.1007/s12149-015-0958-6
更新日期：2015-06-01 00:00:00
abstract：:We evaluated the potential of sodium [1-(11)C]hexanoate (11C-HA) as a radiopharmaceutical with which to assess oxidative metabolism of the brain by PET. 11C-HA, sodium [1-(14)C]acetate and [3H]deoxyglucose were simultaneously injected into mice under control, hypoxic and starving conditions. In the control, the brain ...
journal_title：Annals of nuclear medicine
pub_type： 杂志文章
doi：10.1007/BF03165404
更新日期：1996-05-01 00:00:00
abstract：OBJECTIVE:To investigate the potential role of Tc-99m depreotide (Tc-DEPR) in the preoperative lymph node (N) staging of non-small-cell lung cancer (NSCLC). METHODS:Sixty-one patients with NSCLC at the potentially operable stage were enrolled and underwent scintigraphy before surgery (n=56) or mediastinoscopy (n=5). I...
journal_title：Annals of nuclear medicine
pub_type： 杂志文章
doi：10.1007/s12149-014-0839-4
更新日期：2014-06-01 00:00:00
abstract：OBJECTIVE:Although extensive work has been done on cigarette smoking and its effects on pulmonary function, there are limited number of studies on water-pipe smoking. The effects of water-pipe smoking on health are not widely investigated. The aim of this study was to determine the effects of water-pipe smoking on pulm...
journal_title：Annals of nuclear medicine
pub_type： 临床试验,杂志文章
doi：10.1007/BF02984465
更新日期：2004-06-01 00:00:00
abstract：:We conducted a study of rCBF in the primary visual cortex of visually impaired subjects who have not been subjected to external stimulation for a long period, by means of 123I-IMP SPECT and MRI. The four subjects had lost their sight due to brain tumors (n = 2), glaucoma (n = 1) and trauma (n = 1). 123I-IMP SPECT show...
journal_title：Annals of nuclear medicine
pub_type： 杂志文章
doi：10.1007/BF03164976
更新日期：1995-05-01 00:00:00
abstract：:Tuberculosis peritonitis is a rare manifestation of extrapulmonary tuberculosis. The results of gallium-67 scintigraphy of three patients with tuberculosis peritonitis were reviewed to assess its usefulness in the diagnosis of this condition. Tuberculosis peritonitis was associated with diffuse or focal abdominal loca...
journal_title：Annals of nuclear medicine
pub_type： 杂志文章
doi：10.1007/BF03164860
更新日期：1999-06-01 00:00:00
abstract：:Nerve growth factor (NGF) exerts various actions on neuronal and non-neuronal tissues and has potential therapeutic utility, but difficulties in using the whole protein have stimulated interest in small NGF fragments. We radioiodinated a small cyclic peptide derived from NGF using the Bolton-Hunter method [125I-C(92-9...
journal_title：Annals of nuclear medicine
pub_type： 杂志文章
doi：10.1007/BF03026817
更新日期：2006-10-01 00:00:00
abstract：OBJECTIVE:Variable uptake of 2-deoxy-2-[18F]fluoro-D-glucose (FDG) has been noticed in positron emission tomography (PET) studies of gastric carcinoma patients, with low uptake occurring especially in some particular histological subtypes and early carcinomas. But this phenomenon has not been adequately explained. The ...
journal_title：Annals of nuclear medicine
pub_type： 杂志文章
doi：10.1007/BF02984657
更新日期：2006-11-01 00:00:00
abstract：BACKGROUND:ECG-gated myocardial perfusion SPECT is widely applied to diagnose ischemic heart disease, and such findings are useful to predict patient prognosis. However, Japan does not have a database that correlates SPECT image findings with the prognosis of patients who have ischemic heart disease. METHODS:A large-s...
journal_title：Annals of nuclear medicine
pub_type： 杂志文章,多中心研究
doi：10.1007/BF03027430
更新日期：2006-04-01 00:00:00
abstract：OBJECTIVE:One of the major causes of diabetes and obesity is abnormality in glucose metabolism and glucose uptake in the muscle and adipose tissue based on an insufficient action of insulin. Therefore, many of the drug discovery programs are based on the concept of stimulating glucose uptake in these tissues. Improveme...
journal_title：Annals of nuclear medicine
pub_type： 杂志文章
doi：10.1007/s12149-017-1169-0
更新日期：2017-06-01 00:00:00
abstract：:This case report illustrates the dynamic and static renal scintigraphic images of a patient with an unusual large diverticulum of the renal pelvis. The initial diagnosis by intravenous pyelography (IVP) and ultrasonographic (US) examination was a renal pelvic diverticulum of the left kidney, and the patient was referr...
journal_title：Annals of nuclear medicine
pub_type： 杂志文章
doi：10.1007/BF02985963
更新日期：2004-12-01 00:00:00
abstract：AIM:Computer-aided diagnosis (CAD) software for bone scintigrams have recently been introduced as a clinical quality assurance tool. The purpose of this study was to compare the diagnostic accuracy of two CAD systems, one based on a European and one on a Japanese training database, in a group of bone scans from Japanes...
journal_title：Annals of nuclear medicine
pub_type： 杂志文章
doi：10.1007/s12149-012-0620-5
更新日期：2012-10-01 00:00:00
abstract：OBJECTS:The purpose was to evaluate the correlation of the pre-treatment hematological parameters with metabolic parameters of primary tumor in baseline 18F-FDG PET/CT in patients with colorectal cancer (CRC) and estimate the prognostic value of both. METHODS:We retrospectively investigated 231 patients with CRC who u...
journal_title：Annals of nuclear medicine
pub_type： 杂志文章
doi：10.1007/s12149-018-1299-z
更新日期：2019-01-01 00:00:00
abstract：OBJECTIVE:We investigated the prevalence and clinical significance of incidental focal 18F-FDG uptake in the frontal process of the maxilla, mimicking malignancy on PET/CT. METHODS:From a total of 32,834 patients who underwent 18F-FDG PET/CT, patients with focal uptake in the frontal process of the maxilla were select...
journal_title：Annals of nuclear medicine
pub_type： 杂志文章
doi：10.1007/s12149-016-1103-x
更新日期：2016-11-01 00:00:00
