Immunoglobulin M type of autoantibodies to oxidized low-density lipoprotein has an inverse relation to carotid artery atherosclerosis.

abstract：:Although the postoperative hemodynamic and echocardiographic features of idiopathic hypertrophic subaortic stenosis have been studied, the expected consistent postoperative thinning of the interventricular septum has not been reported. In this study, the short-term effects of septal myectomy were evaluated in 16 patie...

journal_title：Circulation

authors： Schapira JN,Stemple DR,Martin RP,Rakowski H,Stinson EB,Popp RL

更新日期：1978-11-01 00:00:00

abstract：BACKGROUND:Prolonged metabolic abnormalities have been demonstrated previously in postischemic myocardium, including relative increases in glucose uptake and abnormal fatty acid kinetics. However, quantitative metabolic information is limited, and the time course of changes in MVO2 in postischemic myocardium is unknown...

journal_title：Circulation

authors： Buxton DB,Mody FV,Krivokapich J,Phelps ME,Schelbert HR

更新日期：1992-05-01 00:00:00

abstract：:All physicians increasingly will encounter patients who have implanted cardioverter-defibrillators (ICDs) for protection from ventricular arrhythmias. This advisory provides a concise summary relevant to the assessment and management of patients with ICDs, including those who present to primary care or emergency depar...

journal_title：Circulation

authors： Stevenson WG,Chaitman BR,Ellenbogen KA,Epstein AE,Gross WL,Hayes DL,Strickberger SA,Sweeney MO,Subcommittee on Electrocardiography and Arrhythmias of the American Heart Association Council on Clinical Cardiology.,Heart Rhythm Society.

更新日期：2004-12-21 00:00:00

abstract：:A technique is described to control recurrent or sustained supraventricular tachycardia associated with rapid ventricular rates following open heart surgery. The technique utilizes a pair of temporarily implanted atrial epicardial wire electrodes to pace the heart. In one group of patients with recurrent atrial flutte...

journal_title：Circulation

authors： Waldo AL,MacLean WA,Karp RB,Kouchoukos NT,James TN

更新日期：1976-08-01 00:00:00

abstract：:Ten subjects with normal hemodynamics were studied during elective cardiac catheterization with right and left heart multisensor micromanometry to assess hemodynamic responses to the Mueller maneuver. Simultaneous right and left circulatory hemodynamics and left ventricular, pulmonary arterial, and aortic pressures we...

journal_title：Circulation

authors： Condos WR Jr,Latham RD,Hoadley SD,Pasipoularides A

更新日期：1987-11-01 00:00:00

abstract：:To define the mechanisms of unexpected cardiac arrest in advanced heart failure, we reviewed the causes of cardiac arrest as established from electrocardiographic monitoring and from clinical and autopsy data in patients hospitalized for cardiac transplantation evaluation and management of advanced heart failure (mean...

journal_title：Circulation

authors： Luu M,Stevenson WG,Stevenson LW,Baron K,Walden J

更新日期：1989-12-01 00:00:00

abstract：BACKGROUND:Mild oxidation of LDL enhances its atherogenic potential and induces a synergistic interaction with serotonin (5HT) on vascular smooth muscle cell (VSMC) proliferation. Because of its complex chemical nature, the mitogenic components of mildly oxidized LDL (moxLDL) remain unclear. METHODS AND RESULTS:We exa...

journal_title：Circulation

authors： Watanabe T,Pakala R,Koba S,Katagiri T,Benedict CR

更新日期：2001-03-13 00:00:00

abstract：BACKGROUND:Pulmonary arterial hypertension (PAH) remains a concern in patients with β-thalassemia major (TM) and intermedia (TI); however, studies evaluating its prevalence and risk factors using systematic confirmation on right heart catheterization are lacking. METHODS AND RESULTS:This was a multicenter cross-sectio...

journal_title：Circulation

authors： Derchi G,Galanello R,Bina P,Cappellini MD,Piga A,Lai ME,Quarta A,Casu G,Perrotta S,Pinto V,Musallam KM,Forni GL,Webthal Pulmonary Arterial Hypertension Group*.

更新日期：2014-01-21 00:00:00

abstract：BACKGROUND:Drug-coated balloons (DCBs) have shown promise in improving the outcomes for patients with peripheral artery disease. We compared a paclitaxel-coated balloon with percutaneous transluminal angioplasty (PTA) for the treatment of symptomatic superficial femoral and popliteal artery disease. METHODS AND RESULT...

journal_title：Circulation

authors： Tepe G,Laird J,Schneider P,Brodmann M,Krishnan P,Micari A,Metzger C,Scheinert D,Zeller T,Cohen DJ,Snead DB,Alexander B,Landini M,Jaff MR,IN.PACT SFA Trial Investigators.

更新日期：2015-02-03 00:00:00

abstract：BACKGROUND:Acetylsalicylic acid (ASA), or aspirin, plus clopidogrel is becoming the standard antithrombotic treatment in people with coronary disease. Novel approaches such as the use of platelet-selective nitric oxide (NO) donors may provide additional protection against thrombosis. We evaluated the antithrombotic pro...

journal_title：Circulation

authors： Vilahur G,Segalés E,Salas E,Badimon L

更新日期：2004-09-21 00:00:00

abstract：:Cardiac allograft vasculopathy (CAV) remains a troublesome long-term complication of heart transplantation. It is manifested by a unique and unusually accelerated form of coronary disease affecting both intramural and epicardial coronary arteries and veins.CAV is characterized by vascular injury induced by a variety o...

journal_title：Circulation

authors： Weis M,von Scheidt W

更新日期：1997-09-16 00:00:00

abstract：BACKGROUND:Application of pyruvate was shown to improve contractile function in isolated animal myocardium and hemodynamics in patients with congestive heart failure. We assessed the influence of pyruvate on systolic and diastolic myocardial function and its subcellular mode of action in isolated myocardium from end-st...

journal_title：Circulation

authors： Hasenfuss G,Maier LS,Hermann HP,Lüers C,Hünlich M,Zeitz O,Janssen PM,Pieske B

更新日期：2002-01-15 00:00:00

abstract：:A new two-dimensional echocardiographic technique was developed to detect peripheral right coronary aneurysms in Kawasaki disease. Because the main stem of the right coronary artery runs along the tricuspid valve ring and the posterior interventricular groove, these regions were examined for coronary aneurysms using t...

journal_title：Circulation

authors： Yoshida H,Maeda T,Funabashi T,Nakaya S,Takabatake S,Taniguchi N

更新日期：1982-05-01 00:00:00

abstract：BACKGROUND:Adrenergic activation is thought to be an important determinant of outcome in subjects with chronic heart failure (CHF), but baseline or serial changes in adrenergic activity have not been previously investigated in a large patient sample treated with a powerful antiadrenergic agent. METHODS AND RESULTS:Sys...

journal_title：Circulation

authors： Bristow MR,Krause-Steinrauf H,Nuzzo R,Liang CS,Lindenfeld J,Lowes BD,Hattler B,Abraham WT,Olson L,Krueger S,Thaneemit-Chen S,Hare JM,Loeb HS,Domanski MJ,Eichhorn EJ,Zelis R,Lavori P

更新日期：2004-09-14 00:00:00

abstract：:The endothelin (ET) system is comprised of 4 active ETs, with ET-1 being the predominant isoform in the cardiovascular system. Because of the potent vasoconstricting and mitogenic effects of ET-1 and its involvement in various cardiovascular diseases, blockade of the ET receptor has received considerable attention. ET...

journal_title：Circulation

authors： Rich S,McLaughlin VV

更新日期：2003-11-04 00:00:00

abstract：:We assessed the reversibility of functional and morphological changes of arterialized vein segments by returning them to the venous circulation. Thirteen dogs underwent right carotid and femoral veno-arterial grafting. After 12 weeks, veno-arterial grafts were removed for contractility (norepinephrine [NE] and 5-hydro...

journal_title：Circulation

authors： Fann JI,Sokoloff MH,Sarris GE,Yun KL,Kosek JC,Miller DC

更新日期：1990-11-01 00:00:00

abstract：BACKGROUND:In patients with atrial fibrillation, intracardiac atrial defibrillation causes discomfort. An easily applicable, short-acting analgesic and anxiolytic drug would increase acceptability of this new treatment mode. METHODS AND RESULTS:In a double-blind, placebo-controlled manner, the effect of intranasal but...

journal_title：Circulation

authors： Timmermans C,Rodriguez LM,Ayers GM,Lambert H,Smeets JL,Vlaeyen JW,Albert A,Wellens HJ

更新日期：1999-04-13 00:00:00

abstract：BACKGROUND:Since myocardial blood flow changes dynamically after reperfusion and since both hyperemia and impairment in microvascular function exist within the acutely reperfused bed, we sought to investigate the role of myocardial contrast echocardiography (MCE) in (1) defining the temporal variability in perfusion pa...

journal_title：Circulation

authors： Villanueva FS,Glasheen WP,Sklenar J,Kaul S

更新日期：1993-12-01 00:00:00

abstract：BACKGROUND:Cyclooxygenase (COX)-2 contributes to vascular smooth muscle cell (VSMC) proliferation induced by tumor necrosis factor (TNF) and angiotensin II. The present study demonstrates, however, that depending on prevailing conditions, COX-2-derived prostanoids may also inhibit VSMC proliferation. METHODS AND RESUL...

journal_title：Circulation

authors： Haider A,Lee I,Grabarek J,Darzynkiewicz Z,Ferreri NR

更新日期：2003-08-26 00:00:00

abstract：:Disorders associated with the overproduction or delayed clearance of beta-very low density lipoprotein and low density lipoprotein (LDL) are strikingly related to premature coronary artery disease. There are five recognized classes of LDL-lowering drugs, each acting through different basic mechanisms. The increased pr...

journal_title：Circulation

authors： Levy RI,Troendle AJ,Fattu JM

更新日期：1993-04-01 00:00:00

abstract：BACKGROUND:A complete understanding of fluid mechanics in Fontan physiology includes knowledge of the caval contributions to right (RPA) and left (LPA) pulmonary arterial blood flow, total systemic venous return, and relative blood flow to each lung. METHODS AND RESULTS:Ten Fontan patients underwent cine MRI. Three ci...

journal_title：Circulation

authors： Fogel MA,Weinberg PM,Rychik J,Hubbard A,Jacobs M,Spray TL,Haselgrove J

更新日期：1999-03-09 00:00:00

abstract：:Between 1970 and 1987, 112 patients were diagnosed as having thromboangiitis obliterans (TAO). The age was 42 +/- 11 years (mean +/- SD; range, 20-75 years); 23% were women, and 7% were more than 60 years old when they were first diagnosed. Ischemic ulcerations were present in 85 (76%) patients: 24 (28%) patients with...

journal_title：Circulation

authors： Olin JW,Young JR,Graor RA,Ruschhaupt WF,Bartholomew JR

更新日期：1990-11-01 00:00:00

abstract：BACKGROUND:Lymphatic network and chemokine-mediated signals are essential for leukocyte traffic during the proximal steps of alloimmune response. We aimed to determine the role of lymphatic vessels and their principal growth signaling pathway, vascular endothelial growth factor (VEGF)-C/D/VEGFR-3, during acute and chro...

journal_title：Circulation

authors： Nykänen AI,Sandelin H,Krebs R,Keränen MA,Tuuminen R,Kärpänen T,Wu Y,Pytowski B,Koskinen PK,Ylä-Herttuala S,Alitalo K,Lemström KB

更新日期：2010-03-30 00:00:00

abstract：:Organ donor scarcity has resulted in an increasing number of long-distance cardiac allograft procurements. The effect on short-term (90-day) survival and cardiac function was assessed in a consecutive series of 167 heart transplants performed between April 1981 and July 1988. During that time, total allograft ischemic...

journal_title：Circulation

authors： Pflugfelder PW,Thomson D,Singh NR,Menkis AH,McKenzie FN,Kostuk WJ

更新日期：1989-11-01 00:00:00

abstract：:We studied 14 patients to determine whether sustained-release diltiazem is a satisfactory long-term substitute for the combination of propranolol plus hydrochlorothiazide (HCTZ), control phase, in the treatment of systemic hypertension with coexisting chronic stable angina pectoris. All patients had either one- or two...

journal_title：Circulation

authors： Kawanishi DT,Reid CL,Gonzales A,O'Rourke RA,Rahimtoola SH

更新日期：1989-12-01 00:00:00

abstract：:Patients with aortic stenosis develop widely variable patterns of left ventricular hypertrophy and dysfunction. We postulated that coronary atherosclerosis (CAD) may be associated with impaired left ventricular function and chamber dilatation in patients with aortic stenosis. Left ventricular mass and volumes were qua...

journal_title：Circulation

authors： Vekshtein VI,Alexander RW,Yeung AC,Plappert T,Sutton MG,Ganz P,Selwyn AP,Bittl JA

更新日期：1990-12-01 00:00:00

abstract：BACKGROUND:Proto-oncogenes have been implicated in the pathogenesis of gene-mediated myocardial remodeling. In the human heart, however, it has not been clarified whether these proto-oncogenes are related to contractile impairment and structural alteration of the myocardium. The present study is designed to investigate...

journal_title：Circulation

authors： Taketani S,Sawa Y,Taniguchi K,Mitsuno M,Kawaguchi N,Onishi S,Matsuda H

更新日期：1997-11-04 00:00:00

abstract：BACKGROUND:High-speed rotational atherectomy uses a diamond-coated, elliptical burr to abrade occlusive atherosclerosis, especially noncompliant calcified plaque. METHODS AND RESULTS:Intravascular ultrasound (IVUS) was used to analyze 28 patients after atherectomy. Arteries treated and imaged were left main (three), l...

journal_title：Circulation

authors： Mintz GS,Potkin BN,Keren G,Satler LF,Pichard AD,Kent KM,Popma JJ,Leon MB

更新日期：1992-11-01 00:00:00

abstract：BACKGROUND:Thrombolytic therapy of acute myocardial infarction (AMI) is evolving toward bolus administration. Derivatization of proteins with polyethylene glycol (PEG) may reduce their clearance. METHODS AND RESULTS:A staphylokinase (SakSTAR) variant with 12 amino acid substitutions to reduce its antigenicity, SakSTAR...

journal_title：Circulation

authors： Collen D,Sinnaeve P,Demarsin E,Moreau H,De Maeyer M,Jespers L,Laroche Y,Van de Werf F

更新日期：2000-10-10 00:00:00

abstract：:The two new 99m (99mTc) labeled myocardial perfusion agents, 99mTc-Sestamibi and 99mTc-Teboroxime, are now available for routine clinical application. Both agents allow assessment of ejection fraction by the first-pass technique at rest or during exercise, thus providing additional information not available with thall...

journal_title：Circulation

authors： Berman DS,Kiat H,Maddahi J

更新日期：1991-09-01 00:00:00